Angiosarcoma of the forearm definitively treated by hyperfractionated irradiation.
Identifieur interne : 004B59 ( Ncbi/Curation ); précédent : 004B58; suivant : 004B60Angiosarcoma of the forearm definitively treated by hyperfractionated irradiation.
Auteurs : N A Janjan ; T. Anderson ; R. Siegel ; D. HackbarthSource :
- American journal of clinical oncology [ 0277-3732 ] ; 1990.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Hémangiosarcome, Tumeurs des tissus mous.
- radiothérapie : Hémangiosarcome, Tumeurs des tissus mous.
- Adulte, Avant-bras, Doigts, Dosimétrie en radiothérapie, Humains, Mâle.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Hemangiosarcoma, Soft Tissue Neoplasms.
- radiotherapy : Hemangiosarcoma, Soft Tissue Neoplasms.
- Adult, Fingers, Forearm, Humans, Male, Radiotherapy Dosage.
Abstract
A case report of an angiosarcoma treated definitively with hyperfractionated irradiation is presented. Radial and ulnar aspects of the proximal forearm, wrist, and digits were diffusely involved on angiography. Hyperfractionated irradiation totaling 7,440 cGy was delivered to the entire circumference of the hand, forearm, and distal 5 cm of the arm; a confluent dry erythema without moist desquamation was observed at completion of therapy. No significant local or systemic toxicity was noted with the administration of an Adriamycin-containing adjuvant chemotherapy regimen following irradiation. Local regional control at 2 years is documented both clinically and by angiographic examination and the patient otherwise is free of disease. Function remains excellent with no lymphedema or joint fibrosis observed and grip strength of treated and untreated hands is comparable at 35 pounds. For patients refusing amputation or who are otherwise inoperable, hyperfractionated irradiation provides a therapeutic option.
PubMed: 2239804
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N A Janjan<affiliation><nlm:affiliation>Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee 53226.</nlm:affiliation>
<wicri:noCountry code="subField">Milwaukee 53226</wicri:noCountry>
</affiliation>
Le document en format XML
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<author><name sortKey="Siegel, R" sort="Siegel, R" uniqKey="Siegel R" first="R" last="Siegel">R. Siegel</name>
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<author><name sortKey="Janjan, N A" sort="Janjan, N A" uniqKey="Janjan N" first="N A" last="Janjan">N A Janjan</name>
<affiliation><nlm:affiliation>Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee 53226.</nlm:affiliation>
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<series><title level="j">American journal of clinical oncology</title>
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<imprint><date when="1990" type="published">1990</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Fingers</term>
<term>Forearm</term>
<term>Hemangiosarcoma (diagnosis)</term>
<term>Hemangiosarcoma (radiotherapy)</term>
<term>Humans</term>
<term>Male</term>
<term>Radiotherapy Dosage</term>
<term>Soft Tissue Neoplasms (diagnosis)</term>
<term>Soft Tissue Neoplasms (radiotherapy)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Avant-bras</term>
<term>Doigts</term>
<term>Dosimétrie en radiothérapie</term>
<term>Humains</term>
<term>Hémangiosarcome (diagnostic)</term>
<term>Hémangiosarcome (radiothérapie)</term>
<term>Mâle</term>
<term>Tumeurs des tissus mous (diagnostic)</term>
<term>Tumeurs des tissus mous (radiothérapie)</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hemangiosarcoma</term>
<term>Soft Tissue Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Hémangiosarcome</term>
<term>Tumeurs des tissus mous</term>
</keywords>
<keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Hemangiosarcoma</term>
<term>Soft Tissue Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Hémangiosarcome</term>
<term>Tumeurs des tissus mous</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Fingers</term>
<term>Forearm</term>
<term>Humans</term>
<term>Male</term>
<term>Radiotherapy Dosage</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Avant-bras</term>
<term>Doigts</term>
<term>Dosimétrie en radiothérapie</term>
<term>Humains</term>
<term>Mâle</term>
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<front><div type="abstract" xml:lang="en">A case report of an angiosarcoma treated definitively with hyperfractionated irradiation is presented. Radial and ulnar aspects of the proximal forearm, wrist, and digits were diffusely involved on angiography. Hyperfractionated irradiation totaling 7,440 cGy was delivered to the entire circumference of the hand, forearm, and distal 5 cm of the arm; a confluent dry erythema without moist desquamation was observed at completion of therapy. No significant local or systemic toxicity was noted with the administration of an Adriamycin-containing adjuvant chemotherapy regimen following irradiation. Local regional control at 2 years is documented both clinically and by angiographic examination and the patient otherwise is free of disease. Function remains excellent with no lymphedema or joint fibrosis observed and grip strength of treated and untreated hands is comparable at 35 pounds. For patients refusing amputation or who are otherwise inoperable, hyperfractionated irradiation provides a therapeutic option.</div>
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