Angiosarcoma of the forearm definitively treated by hyperfractionated irradiation.
Identifieur interne : 005C51 ( PubMed/Corpus ); précédent : 005C50; suivant : 005C52Angiosarcoma of the forearm definitively treated by hyperfractionated irradiation.
Auteurs : N A Janjan ; T. Anderson ; R. Siegel ; D. HackbarthSource :
- American journal of clinical oncology [ 0277-3732 ] ; 1990.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Hemangiosarcoma, Soft Tissue Neoplasms.
- radiotherapy : Hemangiosarcoma, Soft Tissue Neoplasms.
- Adult, Fingers, Forearm, Humans, Male, Radiotherapy Dosage.
Abstract
A case report of an angiosarcoma treated definitively with hyperfractionated irradiation is presented. Radial and ulnar aspects of the proximal forearm, wrist, and digits were diffusely involved on angiography. Hyperfractionated irradiation totaling 7,440 cGy was delivered to the entire circumference of the hand, forearm, and distal 5 cm of the arm; a confluent dry erythema without moist desquamation was observed at completion of therapy. No significant local or systemic toxicity was noted with the administration of an Adriamycin-containing adjuvant chemotherapy regimen following irradiation. Local regional control at 2 years is documented both clinically and by angiographic examination and the patient otherwise is free of disease. Function remains excellent with no lymphedema or joint fibrosis observed and grip strength of treated and untreated hands is comparable at 35 pounds. For patients refusing amputation or who are otherwise inoperable, hyperfractionated irradiation provides a therapeutic option.
PubMed: 2239804
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pubmed:2239804Le document en format XML
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Hackbarth</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1990">1990</date><idno type="RBID">pubmed:2239804</idno><idno type="pmid">2239804</idno><idno type="wicri:Area/PubMed/Corpus">005C51</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005C51</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Angiosarcoma of the forearm definitively treated by hyperfractionated irradiation.</title><author><name sortKey="Janjan, N A" sort="Janjan, N A" uniqKey="Janjan N" first="N A" last="Janjan">N A Janjan</name><affiliation><nlm:affiliation>Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee 53226.</nlm:affiliation></affiliation></author><author><name sortKey="Anderson, T" sort="Anderson, T" uniqKey="Anderson T" first="T" last="Anderson">T. Anderson</name></author><author><name sortKey="Siegel, R" sort="Siegel, R" uniqKey="Siegel R" first="R" last="Siegel">R. Siegel</name></author><author><name sortKey="Hackbarth, D" sort="Hackbarth, D" uniqKey="Hackbarth D" first="D" last="Hackbarth">D. Hackbarth</name></author></analytic><series><title level="j">American journal of clinical oncology</title><idno type="ISSN">0277-3732</idno><imprint><date when="1990" type="published">1990</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Fingers</term><term>Forearm</term><term>Hemangiosarcoma (diagnosis)</term><term>Hemangiosarcoma (radiotherapy)</term><term>Humans</term><term>Male</term><term>Radiotherapy Dosage</term><term>Soft Tissue Neoplasms (diagnosis)</term><term>Soft Tissue Neoplasms (radiotherapy)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hemangiosarcoma</term><term>Soft Tissue Neoplasms</term></keywords><keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Hemangiosarcoma</term><term>Soft Tissue Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Fingers</term><term>Forearm</term><term>Humans</term><term>Male</term><term>Radiotherapy Dosage</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A case report of an angiosarcoma treated definitively with hyperfractionated irradiation is presented. Radial and ulnar aspects of the proximal forearm, wrist, and digits were diffusely involved on angiography. Hyperfractionated irradiation totaling 7,440 cGy was delivered to the entire circumference of the hand, forearm, and distal 5 cm of the arm; a confluent dry erythema without moist desquamation was observed at completion of therapy. No significant local or systemic toxicity was noted with the administration of an Adriamycin-containing adjuvant chemotherapy regimen following irradiation. Local regional control at 2 years is documented both clinically and by angiographic examination and the patient otherwise is free of disease. Function remains excellent with no lymphedema or joint fibrosis observed and grip strength of treated and untreated hands is comparable at 35 pounds. For patients refusing amputation or who are otherwise inoperable, hyperfractionated irradiation provides a therapeutic option.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2239804</PMID><DateCreated><Year>1990</Year><Month>12</Month><Day>04</Day></DateCreated><DateCompleted><Year>1990</Year><Month>12</Month><Day>04</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0277-3732</ISSN><JournalIssue CitedMedium="Print"><Volume>13</Volume><Issue>6</Issue><PubDate><Year>1990</Year><Month>Dec</Month></PubDate></JournalIssue><Title>American journal of clinical oncology</Title><ISOAbbreviation>Am. J. Clin. Oncol.</ISOAbbreviation></Journal><ArticleTitle>Angiosarcoma of the forearm definitively treated by hyperfractionated irradiation.</ArticleTitle><Pagination><MedlinePgn>489-94</MedlinePgn></Pagination><Abstract><AbstractText>A case report of an angiosarcoma treated definitively with hyperfractionated irradiation is presented. Radial and ulnar aspects of the proximal forearm, wrist, and digits were diffusely involved on angiography. Hyperfractionated irradiation totaling 7,440 cGy was delivered to the entire circumference of the hand, forearm, and distal 5 cm of the arm; a confluent dry erythema without moist desquamation was observed at completion of therapy. No significant local or systemic toxicity was noted with the administration of an Adriamycin-containing adjuvant chemotherapy regimen following irradiation. Local regional control at 2 years is documented both clinically and by angiographic examination and the patient otherwise is free of disease. Function remains excellent with no lymphedema or joint fibrosis observed and grip strength of treated and untreated hands is comparable at 35 pounds. For patients refusing amputation or who are otherwise inoperable, hyperfractionated irradiation provides a therapeutic option.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Janjan</LastName><ForeName>N A</ForeName><Initials>NA</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee 53226.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anderson</LastName><ForeName>T</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Siegel</LastName><ForeName>R</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Hackbarth</LastName><ForeName>D</ForeName><Initials>D</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Am J Clin Oncol</MedlineTA><NlmUniqueID>8207754</NlmUniqueID><ISSNLinking>0277-3732</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005385" MajorTopicYN="N">Fingers</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005542" MajorTopicYN="Y">Forearm</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006394" MajorTopicYN="N">Hemangiosarcoma</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000532" MajorTopicYN="Y">radiotherapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011879" MajorTopicYN="N">Radiotherapy Dosage</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012983" MajorTopicYN="N">Soft Tissue Neoplasms</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000532" MajorTopicYN="Y">radiotherapy</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1990</Year><Month>12</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1990</Year><Month>12</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1990</Year><Month>12</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2239804</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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