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Radiochemotherapy including cisplatin alone versus cisplatin + 5-fluorouracil for locally advanced unresectable stage IV squamous cell carcinoma of the head and neck.

Identifieur interne : 003652 ( Ncbi/Curation ); précédent : 003651; suivant : 003653

Radiochemotherapy including cisplatin alone versus cisplatin + 5-fluorouracil for locally advanced unresectable stage IV squamous cell carcinoma of the head and neck.

Auteurs : Silke Tribius [Allemagne] ; Stefanie Kronemann ; Yasemin Kilic ; Ursula Schroeder ; Samer Hakim ; Steven E. Schild ; Dirk Rades

Source :

RBID : pubmed:19806333

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English descriptors

Abstract

The optimal radiochemotherapy regimen for advanced head-and-neck cancer is still debated. This nonrandomized study compares two cisplatin-based radiochemotherapy regimens in 128 patients with locally advanced unresectable stage IV squamous cell carcinoma of the head and neck (SCCHN).

DOI: 10.1007/s00066-009-1992-x
PubMed: 19806333

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Le document en format XML

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<nlm:affiliation>Department of Radiation Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.</nlm:affiliation>
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<name sortKey="Kilic, Yasemin" sort="Kilic, Yasemin" uniqKey="Kilic Y" first="Yasemin" last="Kilic">Yasemin Kilic</name>
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<title level="j">Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]</title>
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<term>Antineoplastic Combined Chemotherapy Protocols (adverse effects)</term>
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<term>Carcinoma, Squamous Cell (drug therapy)</term>
<term>Carcinoma, Squamous Cell (mortality)</term>
<term>Carcinoma, Squamous Cell (pathology)</term>
<term>Carcinoma, Squamous Cell (radiotherapy)</term>
<term>Chemotherapy, Adjuvant</term>
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<term>Cisplatin (adverse effects)</term>
<term>Combined Modality Therapy</term>
<term>Disease-Free Survival</term>
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<term>Drug Administration Schedule</term>
<term>Female</term>
<term>Fluorouracil (administration & dosage)</term>
<term>Fluorouracil (adverse effects)</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
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<term>Otorhinolaryngologic Neoplasms (mortality)</term>
<term>Otorhinolaryngologic Neoplasms (pathology)</term>
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<term>Retrospective Studies</term>
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<term>Carcinome épidermoïde (radiothérapie)</term>
<term>Carcinome épidermoïde (traitement médicamenteux)</term>
<term>Cisplatine (administration et posologie)</term>
<term>Cisplatine (effets indésirables)</term>
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<term>Fluorouracil (administration et posologie)</term>
<term>Fluorouracil (effets indésirables)</term>
<term>Fractionnement de la dose d'irradiation</term>
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<term>Lésions radio-induites (étiologie)</term>
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<term>Protocoles de polychimiothérapie antinéoplasique (effets indésirables)</term>
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<term>Survie sans rechute</term>
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<term>Tumeurs oto-rhino-laryngologiques (anatomopathologie)</term>
<term>Tumeurs oto-rhino-laryngologiques (mortalité)</term>
<term>Tumeurs oto-rhino-laryngologiques (radiothérapie)</term>
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<term>Études de suivi</term>
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<term>Carcinoma, Squamous Cell</term>
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<term>Lésions radio-induites</term>
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<term>Combined Modality Therapy</term>
<term>Disease-Free Survival</term>
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<term>Drug Administration Schedule</term>
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<term>Follow-Up Studies</term>
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<term>Analyse de survie</term>
<term>Association thérapeutique</term>
<term>Calendrier d'administration des médicaments</term>
<term>Femelle</term>
<term>Fractionnement de la dose d'irradiation</term>
<term>Humains</term>
<term>Mâle</term>
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<front>
<div type="abstract" xml:lang="en">The optimal radiochemotherapy regimen for advanced head-and-neck cancer is still debated. This nonrandomized study compares two cisplatin-based radiochemotherapy regimens in 128 patients with locally advanced unresectable stage IV squamous cell carcinoma of the head and neck (SCCHN).</div>
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