Ecological Meta-Analysis of Density-Dependent Processes in the Transmission of Lymphatic Filariasis: Survival of Infected Vectors
Identifieur interne : 003546 ( Ncbi/Curation ); précédent : 003545; suivant : 003547Ecological Meta-Analysis of Density-Dependent Processes in the Transmission of Lymphatic Filariasis: Survival of Infected Vectors
Auteurs : Edwin Michael [Royaume-Uni] ; Lucy C. Snow [Royaume-Uni] ; Moses J. Bockarie [Royaume-Uni]Source :
- Journal of medical entomology [ 0022-2585 ] ; 2009.
Descripteurs français
- KwdFr :
- Aedes (parasitologie), Animaux, Anopheles (parasitologie), Culex (parasitologie), Culicidae (parasitologie), Densité de population, Filariose lymphatique (parasitologie), Filariose lymphatique (transmission), Humains, Larve, Vecteurs insectes (parasitologie), Wuchereria bancrofti (croissance et développement).
- MESH :
- croissance et développement : Wuchereria bancrofti.
- parasitologie : Aedes, Anopheles, Culex, Culicidae, Filariose lymphatique, Vecteurs insectes.
- transmission : Animaux, Densité de population, Filariose lymphatique, Humains, Larve.
English descriptors
- KwdEn :
- MESH :
- growth & development : Wuchereria bancrofti.
- parasitology : Aedes, Anopheles, Culex, Culicidae, Elephantiasis, Filarial, Insect Vectors.
- transmission : Elephantiasis, Filarial.
- Animals, Humans, Larva, Population Density.
Abstract
The survival rate of infected vectors represents one of the fundamental components that influence the transmission dynamics of mosquito-borne diseases. Despite the occurrence of a number of studies investigating mosquito survival after infection with filarial worms, there remains conflicting evidence from both laboratory and field experiments as to the existence and mechanism for parasite-induced mortality among filarial mosquitoes. Here, we used a mixed effects meta-analytical framework to combine the data from all available vector–human host blood feeding experiments to evaluate the evidence for the impact of parasite load on the mortality rates of the three major lymphatic filariasis transmitting mosquito genera,
Url:
PubMed: 19645292
PubMed Central: 2747083
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002779
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :002778
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :003759
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002D89
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :002D89
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002D89
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :003546
Links to Exploration step
PMC:2747083Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Ecological Meta-Analysis of Density-Dependent Processes in the Transmission of Lymphatic Filariasis: Survival of Infected Vectors</title>
<author><name sortKey="Michael, Edwin" sort="Michael, Edwin" uniqKey="Michael E" first="Edwin" last="Michael">Edwin Michael</name>
<affiliation wicri:level="1"><nlm:aff id="A1"> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG</wicri:regionArea>
<wicri:noRegion>London W2 1PG</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Snow, Lucy C" sort="Snow, Lucy C" uniqKey="Snow L" first="Lucy C." last="Snow">Lucy C. Snow</name>
<affiliation wicri:level="1"><nlm:aff id="A1"> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG</wicri:regionArea>
<wicri:noRegion>London W2 1PG</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2"> Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NE, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NE</wicri:regionArea>
<wicri:noRegion>Addlestone KT15 3NE</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bockarie, Moses J" sort="Bockarie, Moses J" uniqKey="Bockarie M" first="Moses J." last="Bockarie">Moses J. Bockarie</name>
<affiliation wicri:level="1"><nlm:aff id="A3"> Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA</wicri:regionArea>
<wicri:noRegion>Liverpool L3 5QA</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">19645292</idno>
<idno type="pmc">2747083</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747083</idno>
<idno type="RBID">PMC:2747083</idno>
<date when="2009">2009</date>
<idno type="wicri:Area/Pmc/Corpus">002779</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002779</idno>
<idno type="wicri:Area/Pmc/Curation">002778</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002778</idno>
<idno type="wicri:Area/Pmc/Checkpoint">003759</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">003759</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002D89</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002D89</idno>
<idno type="wicri:Area/PubMed/Curation">002D89</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002D89</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002D89</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002D89</idno>
<idno type="wicri:Area/Ncbi/Merge">003546</idno>
<idno type="wicri:Area/Ncbi/Curation">003546</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Ecological Meta-Analysis of Density-Dependent Processes in the Transmission of Lymphatic Filariasis: Survival of Infected Vectors</title>
<author><name sortKey="Michael, Edwin" sort="Michael, Edwin" uniqKey="Michael E" first="Edwin" last="Michael">Edwin Michael</name>
<affiliation wicri:level="1"><nlm:aff id="A1"> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG</wicri:regionArea>
<wicri:noRegion>London W2 1PG</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Snow, Lucy C" sort="Snow, Lucy C" uniqKey="Snow L" first="Lucy C." last="Snow">Lucy C. Snow</name>
<affiliation wicri:level="1"><nlm:aff id="A1"> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London W2 1PG</wicri:regionArea>
<wicri:noRegion>London W2 1PG</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2"> Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NE, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, New Haw, Addlestone KT15 3NE</wicri:regionArea>
<wicri:noRegion>Addlestone KT15 3NE</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bockarie, Moses J" sort="Bockarie, Moses J" uniqKey="Bockarie M" first="Moses J." last="Bockarie">Moses J. Bockarie</name>
<affiliation wicri:level="1"><nlm:aff id="A3"> Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea> Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA</wicri:regionArea>
<wicri:noRegion>Liverpool L3 5QA</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of medical entomology</title>
<idno type="ISSN">0022-2585</idno>
<imprint><date when="2009">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aedes (parasitology)</term>
<term>Animals</term>
<term>Anopheles (parasitology)</term>
<term>Culex (parasitology)</term>
<term>Culicidae (parasitology)</term>
<term>Elephantiasis, Filarial (parasitology)</term>
<term>Elephantiasis, Filarial (transmission)</term>
<term>Humans</term>
<term>Insect Vectors (parasitology)</term>
<term>Larva</term>
<term>Population Density</term>
<term>Wuchereria bancrofti (growth & development)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Aedes (parasitologie)</term>
<term>Animaux</term>
<term>Anopheles (parasitologie)</term>
<term>Culex (parasitologie)</term>
<term>Culicidae (parasitologie)</term>
<term>Densité de population</term>
<term>Filariose lymphatique (parasitologie)</term>
<term>Filariose lymphatique (transmission)</term>
<term>Humains</term>
<term>Larve</term>
<term>Vecteurs insectes (parasitologie)</term>
<term>Wuchereria bancrofti (croissance et développement)</term>
</keywords>
<keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Wuchereria bancrofti</term>
</keywords>
<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Wuchereria bancrofti</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Aedes</term>
<term>Anopheles</term>
<term>Culex</term>
<term>Culicidae</term>
<term>Filariose lymphatique</term>
<term>Vecteurs insectes</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Aedes</term>
<term>Anopheles</term>
<term>Culex</term>
<term>Culicidae</term>
<term>Elephantiasis, Filarial</term>
<term>Insect Vectors</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Humans</term>
<term>Larva</term>
<term>Population Density</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="fr"><term>Animaux</term>
<term>Densité de population</term>
<term>Filariose lymphatique</term>
<term>Humains</term>
<term>Larve</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">The survival rate of infected vectors represents one of the fundamental components that influence the transmission dynamics of mosquito-borne diseases. Despite the occurrence of a number of studies investigating mosquito survival after infection with filarial worms, there remains conflicting evidence from both laboratory and field experiments as to the existence and mechanism for parasite-induced mortality among filarial mosquitoes. Here, we used a mixed effects meta-analytical framework to combine the data from all available vector–human host blood feeding experiments to evaluate the evidence for the impact of parasite load on the mortality rates of the three major lymphatic filariasis transmitting mosquito genera, <italic>Culex</italic>
, <italic>Aedes</italic>
, and <italic>Anopheles</italic>
mosquitoes, over the extrinsic incubation period of parasitic infection. The results show that, despite the application of this approach, or in the case of <italic>Anopheles</italic>
using a convention fixed effects logistic regression analysis supplemented with additional survival analysis of longitudinal data, no strong association between mortality rate and microfilariae (mf) uptake for either of the three mosquito genera is apparent in the combined data. Instead, a key finding is that study effects played a more crucial role in determining the levels of mortality observed in these experimental studies. This was most revealing in the case of <italic>Culex</italic>
, given that the largest single study in terms of both the number of data points and range of mf intensities, in contrast to smaller studies, showed a significant positive association between mf intensity and mortality, indicating that in this genus at least, the detrimental effect of infection may be manifested only at the highest mf intakes. Although no density dependence in vector mortality was also observed for <italic>Aedes</italic>
, possibly because of the use of restricted human mf intensity range in previous studies, an intriguing finding was that a significantly higher overall mortality was observed for this genus over mf intake ranges that produced much less corresponding mortality in <italic>Culex</italic>
and <italic>Anopheles</italic>
. The results also indicate that currently very little can be said about the survival rate of <italic>Anopheles</italic>
mosquitoes infected with filarial worms because of the striking paucity of data for this genus. Further studies, using standardized methods and covering an appropriate range of mf uptake intensities and using study frameworks that allow the design and comparison of data from both experimental and field experiments, are clearly indicated if we are to reliably quantify the likely effect of filarial infection on vector survival.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003546 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 003546 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:2747083 |texte= Ecological Meta-Analysis of Density-Dependent Processes in the Transmission of Lymphatic Filariasis: Survival of Infected Vectors }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:19645292" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
![]() | This area was generated with Dilib version V0.6.31. | ![]() |