Lymphoedema/hypercalcaemia syndrome mediated by parathyroid-hormone-related protein.
Identifieur interne : 002242 ( Ncbi/Curation ); précédent : 002241; suivant : 002243Lymphoedema/hypercalcaemia syndrome mediated by parathyroid-hormone-related protein.
Auteurs : S. Braude [Royaume-Uni] ; A. Graham ; D. MitchellSource :
- Lancet (London, England) [ 0140-6736 ] ; 1991.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Hyperparathyroïdie.
- métabolisme : Protéines.
- sang : Hormone parathyroïdienne, Hypercalcémie, Lymphoedème.
- Adulte, Femelle, Humains, Hypercalcémie, Lymphoedème, Protéine apparentée à l'hormone parathyroïdienne, Syndrome.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Parathyroid Hormone.
- blood : Hypercalcemia, Lymphedema.
- complications : Hypercalcemia, Lymphedema.
- diagnosis : Hyperparathyroidism.
- chemical , metabolism : Proteins.
- Adult, Female, Humans, Parathyroid Hormone-Related Protein, Syndrome.
Abstract
A 24-year-old woman presented with a cryptogenic, hypercalcaemic syndrome with metastatic pulmonary calcification and leg and massive breast enlargement and bilateral chylous pleural effusions compatible with a generalised lymphatic abnormality. The patient's serum parathyroid hormone-related protein concentration was very high at a time when she was significantly hypercalcaemic, implying that the hypercalcaemia was mediated by this protein.
PubMed: 1670789
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pubmed:1670789Le document en format XML
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<affiliation wicri:level="3"><nlm:affiliation>Royal Brompton, National Heart Hospital, London, UK.</nlm:affiliation>
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<wicri:regionArea>Royal Brompton, National Heart Hospital, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
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<author><name sortKey="Graham, A" sort="Graham, A" uniqKey="Graham A" first="A" last="Graham">A. Graham</name>
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<author><name sortKey="Mitchell, D" sort="Mitchell, D" uniqKey="Mitchell D" first="D" last="Mitchell">D. Mitchell</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Lymphoedema/hypercalcaemia syndrome mediated by parathyroid-hormone-related protein.</title>
<author><name sortKey="Braude, S" sort="Braude, S" uniqKey="Braude S" first="S" last="Braude">S. Braude</name>
<affiliation wicri:level="3"><nlm:affiliation>Royal Brompton, National Heart Hospital, London, UK.</nlm:affiliation>
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<author><name sortKey="Mitchell, D" sort="Mitchell, D" uniqKey="Mitchell D" first="D" last="Mitchell">D. Mitchell</name>
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<series><title level="j">Lancet (London, England)</title>
<idno type="ISSN">0140-6736</idno>
<imprint><date when="1991" type="published">1991</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Female</term>
<term>Humans</term>
<term>Hypercalcemia (blood)</term>
<term>Hypercalcemia (complications)</term>
<term>Hyperparathyroidism (diagnosis)</term>
<term>Lymphedema (blood)</term>
<term>Lymphedema (complications)</term>
<term>Parathyroid Hormone (blood)</term>
<term>Parathyroid Hormone-Related Protein</term>
<term>Proteins (metabolism)</term>
<term>Syndrome</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Femelle</term>
<term>Hormone parathyroïdienne (sang)</term>
<term>Humains</term>
<term>Hypercalcémie ()</term>
<term>Hypercalcémie (sang)</term>
<term>Hyperparathyroïdie (diagnostic)</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (sang)</term>
<term>Protéine apparentée à l'hormone parathyroïdienne</term>
<term>Protéines (métabolisme)</term>
<term>Syndrome</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Parathyroid Hormone</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Hypercalcemia</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Hypercalcemia</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hyperparathyroidism</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Hyperparathyroïdie</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Hormone parathyroïdienne</term>
<term>Hypercalcémie</term>
<term>Lymphoedème</term>
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<term>Female</term>
<term>Humans</term>
<term>Parathyroid Hormone-Related Protein</term>
<term>Syndrome</term>
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<term>Femelle</term>
<term>Humains</term>
<term>Hypercalcémie</term>
<term>Lymphoedème</term>
<term>Protéine apparentée à l'hormone parathyroïdienne</term>
<term>Syndrome</term>
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<front><div type="abstract" xml:lang="en">A 24-year-old woman presented with a cryptogenic, hypercalcaemic syndrome with metastatic pulmonary calcification and leg and massive breast enlargement and bilateral chylous pleural effusions compatible with a generalised lymphatic abnormality. The patient's serum parathyroid hormone-related protein concentration was very high at a time when she was significantly hypercalcaemic, implying that the hypercalcaemia was mediated by this protein.</div>
</front>
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</record>
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