Lymph-node staining with activated carbon CH40: a new method for axillary lymph-node dissection in breast cancer
Identifieur interne : 000350 ( Ncbi/Curation ); précédent : 000349; suivant : 000351Lymph-node staining with activated carbon CH40: a new method for axillary lymph-node dissection in breast cancer
Auteurs : Takashi Yokota ; Toshihiro Saito ; Yoichi Narushima ; Kazutsugu Iwamoto ; Masashi Iizuka ; Akeo Hagiwara ; Kiyoshi Sawai ; Shu Kikuchi ; Yasuo Kunii ; Hidemi YamauchiSource :
- Canadian Journal of Surgery [ 0008-428X ] ; 2000.
Abstract
To demonstrate the usefulness of activated carbon particles (CH40) as a vital staining dye for visualizing lymphatic vessels and lymph nodes in breast cancer.
A retrospective evaluation.
Department of Surgery in Sendai National Hospital, Japan, a 716-bed teaching hospital.
To identify as many lymph nodes as possible in the axillary fat, by which we might decrease the possibility of the presence of undetected metastatic nodes, an emulsion of activated carbon particles (CH40) was injected into the centre of the mammary gland, close to the tumour site, 3 days before radical surgery.
The number of lymph nodes found by the traditional method and by the CH40-injection method were recorded.
After injection, the CH40 was readily adsorbed into regional lymphatics and streamed along with the lymph flow to blacken regional lymph nodes. The CH40-guided method increased the mean number of nodes per case found in the axilla from 8.4, by the traditional method, to 14.0 nodes per case.
The use of the CH40 technique has two technical advantages; one is that it allows surgeons to locate the blackened lymph nodes at the time of surgery and the other is that it allows pathologists to look for the nodes in fatty tissue. Lymph-node dissection with the aid of activated carbon particles is inexpensive, easy to perform and enables the smallest lymph nodes to be easily recognized. CH40 is the technique of choice for the detection of axillary lymph nodes in cases where the number of lymph nodes detected by the traditional method is too small for accurate surgery. In conclusion, the present study demonstrates that CH40 could be an appropriate tool for more accurate staging of breast cancer axillary specimens.
Url:
PubMed: 10851412
PubMed Central: 3695160
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uniqKey="Hagiwara A" first="Akeo" last="Hagiwara">Akeo Hagiwara</name></author><author><name sortKey="Sawai, Kiyoshi" sort="Sawai, Kiyoshi" uniqKey="Sawai K" first="Kiyoshi" last="Sawai">Kiyoshi Sawai</name></author><author><name sortKey="Kikuchi, Shu" sort="Kikuchi, Shu" uniqKey="Kikuchi S" first="Shu" last="Kikuchi">Shu Kikuchi</name></author><author><name sortKey="Kunii, Yasuo" sort="Kunii, Yasuo" uniqKey="Kunii Y" first="Yasuo" last="Kunii">Yasuo Kunii</name></author><author><name sortKey="Yamauchi, Hidemi" sort="Yamauchi, Hidemi" uniqKey="Yamauchi H" first="Hidemi" last="Yamauchi">Hidemi Yamauchi</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">10851412</idno><idno type="pmc">3695160</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695160</idno><idno type="RBID">PMC:3695160</idno><date when="2000">2000</date><idno type="wicri:Area/Pmc/Corpus">002D26</idno><idno type="wicri:explorRef" wicri:stream="Pmc" 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uniqKey="Narushima Y" first="Yoichi" last="Narushima">Yoichi Narushima</name></author><author><name sortKey="Iwamoto, Kazutsugu" sort="Iwamoto, Kazutsugu" uniqKey="Iwamoto K" first="Kazutsugu" last="Iwamoto">Kazutsugu Iwamoto</name></author><author><name sortKey="Iizuka, Masashi" sort="Iizuka, Masashi" uniqKey="Iizuka M" first="Masashi" last="Iizuka">Masashi Iizuka</name></author><author><name sortKey="Hagiwara, Akeo" sort="Hagiwara, Akeo" uniqKey="Hagiwara A" first="Akeo" last="Hagiwara">Akeo Hagiwara</name></author><author><name sortKey="Sawai, Kiyoshi" sort="Sawai, Kiyoshi" uniqKey="Sawai K" first="Kiyoshi" last="Sawai">Kiyoshi Sawai</name></author><author><name sortKey="Kikuchi, Shu" sort="Kikuchi, Shu" uniqKey="Kikuchi S" first="Shu" last="Kikuchi">Shu Kikuchi</name></author><author><name sortKey="Kunii, Yasuo" sort="Kunii, Yasuo" uniqKey="Kunii Y" first="Yasuo" last="Kunii">Yasuo Kunii</name></author><author><name sortKey="Yamauchi, Hidemi" sort="Yamauchi, Hidemi" uniqKey="Yamauchi H" first="Hidemi" last="Yamauchi">Hidemi Yamauchi</name></author></analytic><series><title level="j">Canadian Journal of Surgery</title><idno type="ISSN">0008-428X</idno><idno type="eISSN">1488-2310</idno><imprint><date when="2000">2000</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objective</title><p>To demonstrate the usefulness of activated carbon particles (CH40) as a vital staining dye for visualizing lymphatic vessels and lymph nodes in breast cancer.</p></sec><sec><title>Design</title><p>A retrospective evaluation.</p></sec><sec><title>Setting</title><p>Department of Surgery in Sendai National Hospital, Japan, a 716-bed teaching hospital.</p></sec><sec><title>Methods</title><p>To identify as many lymph nodes as possible in the axillary fat, by which we might decrease the possibility of the presence of undetected metastatic nodes, an emulsion of activated carbon particles (CH40) was injected into the centre of the mammary gland, close to the tumour site, 3 days before radical surgery.</p></sec><sec><title>Main outcome measure</title><p>The number of lymph nodes found by the traditional method and by the CH40-injection method were recorded.</p></sec><sec><title>Results</title><p>After injection, the CH40 was readily adsorbed into regional lymphatics and streamed along with the lymph flow to blacken regional lymph nodes. The CH40-guided method increased the mean number of nodes per case found in the axilla from 8.4, by the traditional method, to 14.0 nodes per case.</p></sec><sec><title>Conclusions</title><p>The use of the CH40 technique has two technical advantages; one is that it allows surgeons to locate the blackened lymph nodes at the time of surgery and the other is that it allows pathologists to look for the nodes in fatty tissue. Lymph-node dissection with the aid of activated carbon particles is inexpensive, easy to perform and enables the smallest lymph nodes to be easily recognized. CH40 is the technique of choice for the detection of axillary lymph nodes in cases where the number of lymph nodes detected by the traditional method is too small for accurate surgery. In conclusion, the present study demonstrates that CH40 could be an appropriate tool for more accurate staging of breast cancer axillary specimens.</p></sec></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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