HLA and filariasis in Sri Lankans and Indians.
Identifieur interne : 00FF86 ( Main/Merge ); précédent : 00FF85; suivant : 00FF87HLA and filariasis in Sri Lankans and Indians.
Auteurs : S H Chan ; S. Dissanayake ; J W Mak ; M M Ismail ; G B Wee ; N. Srinivasan ; B H Soo ; V. ZamanSource :
- The Southeast Asian journal of tropical medicine and public health [ 0125-1562 ] ; 1984.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Antigènes HLA, Filarioses, Lymphoedème, Éléphantiasis.
- immunologie : Filarioses, Éléphantiasis.
- Femelle, Humains, Malaisie, Mâle, Population d'origine asiatique, Singapour, Sri Lanka, Susceptibilité à une maladie.
- Wicri :
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : HLA Antigens.
- geographic : Malaysia, Singapore, Sri Lanka.
- genetics : Elephantiasis, Filariasis, Lymphedema.
- immunology : Elephantiasis, Filariasis.
- Asian Continental Ancestry Group, Disease Susceptibility, Female, Humans, Male.
Abstract
Similar HLA association was found in patients with elephantiasis in Sri Lankans and Southern Indians. HLA-B15 was observed in 13/44 (30%) Sri Lankan patients with elephantiasis compared to 1/27 (4%) Sri Lankan controls (p = .0058; RR = 10.9) and in 5/8 (28%) Southern Indian elephantiasis compared to 10/101 (10%) Southern Indian controls (p = 0.04; RR = 3.5). In combining the data, the significance of the difference of the frequency of B15 between patients with elephantiasis and controls was even more marked (p = 0.00045; corrected p = 0.012; RR = 4.4).
PubMed: 6523169
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pubmed:6523169Le document en format XML
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<author><name sortKey="Chan, S H" sort="Chan, S H" uniqKey="Chan S" first="S H" last="Chan">S H Chan</name>
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<author><name sortKey="Dissanayake, S" sort="Dissanayake, S" uniqKey="Dissanayake S" first="S" last="Dissanayake">S. Dissanayake</name>
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<author><name sortKey="Mak, J W" sort="Mak, J W" uniqKey="Mak J" first="J W" last="Mak">J W Mak</name>
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<author><name sortKey="Ismail, M M" sort="Ismail, M M" uniqKey="Ismail M" first="M M" last="Ismail">M M Ismail</name>
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<author><name sortKey="Wee, G B" sort="Wee, G B" uniqKey="Wee G" first="G B" last="Wee">G B Wee</name>
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<author><name sortKey="Srinivasan, N" sort="Srinivasan, N" uniqKey="Srinivasan N" first="N" last="Srinivasan">N. Srinivasan</name>
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<author><name sortKey="Soo, B H" sort="Soo, B H" uniqKey="Soo B" first="B H" last="Soo">B H Soo</name>
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<author><name sortKey="Zaman, V" sort="Zaman, V" uniqKey="Zaman V" first="V" last="Zaman">V. Zaman</name>
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<author><name sortKey="Mak, J W" sort="Mak, J W" uniqKey="Mak J" first="J W" last="Mak">J W Mak</name>
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<author><name sortKey="Ismail, M M" sort="Ismail, M M" uniqKey="Ismail M" first="M M" last="Ismail">M M Ismail</name>
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<author><name sortKey="Wee, G B" sort="Wee, G B" uniqKey="Wee G" first="G B" last="Wee">G B Wee</name>
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<author><name sortKey="Soo, B H" sort="Soo, B H" uniqKey="Soo B" first="B H" last="Soo">B H Soo</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Asian Continental Ancestry Group</term>
<term>Disease Susceptibility</term>
<term>Elephantiasis (genetics)</term>
<term>Elephantiasis (immunology)</term>
<term>Female</term>
<term>Filariasis (genetics)</term>
<term>Filariasis (immunology)</term>
<term>HLA Antigens (genetics)</term>
<term>Humans</term>
<term>Lymphedema (genetics)</term>
<term>Malaysia</term>
<term>Male</term>
<term>Singapore</term>
<term>Sri Lanka</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Antigènes HLA (génétique)</term>
<term>Femelle</term>
<term>Filarioses (génétique)</term>
<term>Filarioses (immunologie)</term>
<term>Humains</term>
<term>Lymphoedème (génétique)</term>
<term>Malaisie</term>
<term>Mâle</term>
<term>Population d'origine asiatique</term>
<term>Singapour</term>
<term>Sri Lanka</term>
<term>Susceptibilité à une maladie</term>
<term>Éléphantiasis (génétique)</term>
<term>Éléphantiasis (immunologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>HLA Antigens</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Malaysia</term>
<term>Singapore</term>
<term>Sri Lanka</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Elephantiasis</term>
<term>Filariasis</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Antigènes HLA</term>
<term>Filarioses</term>
<term>Lymphoedème</term>
<term>Éléphantiasis</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Filarioses</term>
<term>Éléphantiasis</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis</term>
<term>Filariasis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Asian Continental Ancestry Group</term>
<term>Disease Susceptibility</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Femelle</term>
<term>Humains</term>
<term>Malaisie</term>
<term>Mâle</term>
<term>Population d'origine asiatique</term>
<term>Singapour</term>
<term>Sri Lanka</term>
<term>Susceptibilité à une maladie</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Malaisie</term>
<term>Singapour</term>
<term>Sri Lanka</term>
</keywords>
</textClass>
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<front><div type="abstract" xml:lang="en">Similar HLA association was found in patients with elephantiasis in Sri Lankans and Southern Indians. HLA-B15 was observed in 13/44 (30%) Sri Lankan patients with elephantiasis compared to 1/27 (4%) Sri Lankan controls (p = .0058; RR = 10.9) and in 5/8 (28%) Southern Indian elephantiasis compared to 10/101 (10%) Southern Indian controls (p = 0.04; RR = 3.5). In combining the data, the significance of the difference of the frequency of B15 between patients with elephantiasis and controls was even more marked (p = 0.00045; corrected p = 0.012; RR = 4.4).</div>
</front>
</TEI>
</record>
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