Sequelae following axillary lymph node dissection for breast cancer
Identifieur interne : 007F66 ( Main/Merge ); précédent : 007F65; suivant : 007F67Sequelae following axillary lymph node dissection for breast cancer
Auteurs : George H. Sakorofas [Grèce] ; George Peros [Grèce] ; Luigi Cataliotti [Grèce]Source :
- Expert review of anticancer therapy [ 1473-7140 ] ; 2006.
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Abstract
Axillary lymph node dissection (ALND) has a central role in the surgical management of breast cancer; however, it is associated with a potentially significant morbidity. Although post-ALND complications are often minor, in some cases they can persist for a long time following surgery, thereby affecting the quality of life of breast cancer survivors. Seroma formation and altered sensation of the upper limb are the two most common complications following ALND. Lymphedema is the most common potentially severe long-term complication following ALND. Major post-ALND complications (such as injury or thrombosis of the axillary vein and injury to the motor nerves of the axilla) are extremely rare. Meticulous surgical technique and careful selection of patients for postoperative radiation therapy are mandatory to prevent significant morbidity following ALND. The introduction of the technique of sentinel lymph node biopsy in clinical practice has resulted in a significant reduction in the incidence of post-ALND complications.
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Sakorofas</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Attikon University Hospital, 4th Department of Surgery, Athens University, Medical School, Arkadias 19-21</s1><s2>11526, Athens</s2><s3>GRC</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Peros, George" sort="Peros, George" uniqKey="Peros G" first="George" last="Peros">George Peros</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Attikon University Hospital, 4th Department of Surgery, Athens University, Medical School, Arkadias 19-21</s1><s2>11526, Athens</s2><s3>GRC</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Cataliotti, Luigi" sort="Cataliotti, Luigi" uniqKey="Cataliotti L" first="Luigi" last="Cataliotti">Luigi Cataliotti</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Attikon University Hospital, 4th Department of Surgery, Athens University, Medical School, Arkadias 19-21</s1><s2>11526, Athens</s2><s3>GRC</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">07-0018677</idno><date when="2006">2006</date><idno type="stanalyst">PASCAL 07-0018677 INIST</idno><idno type="RBID">Pascal:07-0018677</idno><idno type="wicri:Area/PascalFrancis/Corpus">000501</idno><idno type="wicri:Area/PascalFrancis/Curation">000459</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000506</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000506</idno><idno type="wicri:doubleKey">1473-7140:2006:Sakorofas G:sequelae:following:axillary</idno><idno type="wicri:Area/Main/Merge">007F66</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Sequelae following axillary lymph node dissection for breast cancer</title><author><name sortKey="Sakorofas, George H" sort="Sakorofas, George H" uniqKey="Sakorofas G" first="George H." last="Sakorofas">George H. Sakorofas</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Attikon University Hospital, 4th Department of Surgery, Athens University, Medical School, Arkadias 19-21</s1><s2>11526, Athens</s2><s3>GRC</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Peros, George" sort="Peros, George" uniqKey="Peros G" first="George" last="Peros">George Peros</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Attikon University Hospital, 4th Department of Surgery, Athens University, Medical School, Arkadias 19-21</s1><s2>11526, Athens</s2><s3>GRC</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Cataliotti, Luigi" sort="Cataliotti, Luigi" uniqKey="Cataliotti L" first="Luigi" last="Cataliotti">Luigi Cataliotti</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Attikon University Hospital, 4th Department of Surgery, Athens University, Medical School, Arkadias 19-21</s1><s2>11526, Athens</s2><s3>GRC</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Expert review of anticancer therapy</title><title level="j" type="abbreviated">Expert rev. anticancer ther.</title><idno type="ISSN">1473-7140</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Expert review of anticancer therapy</title><title level="j" type="abbreviated">Expert rev. anticancer ther.</title><idno type="ISSN">1473-7140</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Axillary ganglion</term><term>Breast cancer</term><term>Complication</term><term>Lymphadenectomy</term><term>Lymphedema</term><term>Morbidity</term><term>Pain</term><term>Quality of life</term><term>Relapse</term><term>Seroma</term><term>Treatment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Ganglion axillaire</term><term>Lymphadénectomie</term><term>Complication</term><term>Lymphoedème</term><term>Morbidité</term><term>Douleur</term><term>Qualité vie</term><term>Récidive</term><term>Traitement</term><term>Cancer du sein</term><term>Sérome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Axillary lymph node dissection (ALND) has a central role in the surgical management of breast cancer; however, it is associated with a potentially significant morbidity. Although post-ALND complications are often minor, in some cases they can persist for a long time following surgery, thereby affecting the quality of life of breast cancer survivors. Seroma formation and altered sensation of the upper limb are the two most common complications following ALND. Lymphedema is the most common potentially severe long-term complication following ALND. Major post-ALND complications (such as injury or thrombosis of the axillary vein and injury to the motor nerves of the axilla) are extremely rare. Meticulous surgical technique and careful selection of patients for postoperative radiation therapy are mandatory to prevent significant morbidity following ALND. The introduction of the technique of sentinel lymph node biopsy in clinical practice has resulted in a significant reduction in the incidence of post-ALND complications.</div></front></TEI><affiliations><list><country><li>Grèce</li></country><region><li>Attique (région)</li></region><settlement><li>Athènes</li></settlement></list><tree><country name="Grèce"><region name="Attique (région)"><name sortKey="Sakorofas, George H" sort="Sakorofas, George H" uniqKey="Sakorofas G" first="George H." last="Sakorofas">George H. Sakorofas</name></region><name sortKey="Cataliotti, Luigi" sort="Cataliotti, Luigi" uniqKey="Cataliotti L" first="Luigi" last="Cataliotti">Luigi Cataliotti</name><name sortKey="Peros, George" sort="Peros, George" uniqKey="Peros G" first="George" last="Peros">George Peros</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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