Primary cutaneous angiosarcoma of the breast after breast trauma
Identifieur interne : 004005 ( Main/Merge ); précédent : 004004; suivant : 004006Primary cutaneous angiosarcoma of the breast after breast trauma
Auteurs : Ying Cao ; Laura Panos ; Robbie L. Graham ; Thornwell H. Parker ; Robert MennelSource :
- Proceedings (Baylor University. Medical Center) [ 0899-8280 ] ; 2012.
Abstract
Primary angiosarcoma of the breast is a rare malignant tumor. We report a case of breast primary cutaneous angiosarcoma in a patient with a strong family history of malignancy. For definitive diagnosis, a tissue biopsy is needed, with immunostaining for the presence of blood vessel endothelial markers CD31 and CD34. Total mastectomy is the preferred method of surgical treatment. Chemotherapy has not been shown to increase overall survival, but in some instances it may improve local control and disease-free survival. Surgery combined with radiation may increase local control, but patients at high risk of recurrence may benefit from adjuvant treatment as well. We discuss the potential benefits from various treatments for primary cutaneous breast angiosarcoma.
Url:
PubMed: 22275789
PubMed Central: 3246859
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PMC:3246859Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Primary angiosarcoma of the breast is a rare malignant tumor. We report a case of breast primary cutaneous angiosarcoma in a patient with a strong family history of malignancy. For definitive diagnosis, a tissue biopsy is needed, with immunostaining for the presence of blood vessel endothelial markers CD31 and CD34. Total mastectomy is the preferred method of surgical treatment. Chemotherapy has not been shown to increase overall survival, but in some instances it may improve local control and disease-free survival. Surgery combined with radiation may increase local control, but patients at high risk of recurrence may benefit from adjuvant treatment as well. We discuss the potential benefits from various treatments for primary cutaneous breast angiosarcoma.</p>
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