Primary cutaneous angiosarcoma of the breast after breast trauma
Identifieur interne : 003153 ( Pmc/Curation ); précédent : 003152; suivant : 003154Primary cutaneous angiosarcoma of the breast after breast trauma
Auteurs : Ying Cao ; Laura Panos ; Robbie L. Graham ; Thornwell H. Parker ; Robert MennelSource :
- Proceedings (Baylor University. Medical Center) [ 0899-8280 ] ; 2012.
Abstract
Primary angiosarcoma of the breast is a rare malignant tumor. We report a case of breast primary cutaneous angiosarcoma in a patient with a strong family history of malignancy. For definitive diagnosis, a tissue biopsy is needed, with immunostaining for the presence of blood vessel endothelial markers CD31 and CD34. Total mastectomy is the preferred method of surgical treatment. Chemotherapy has not been shown to increase overall survival, but in some instances it may improve local control and disease-free survival. Surgery combined with radiation may increase local control, but patients at high risk of recurrence may benefit from adjuvant treatment as well. We discuss the potential benefits from various treatments for primary cutaneous breast angiosarcoma.
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PubMed: 22275789
PubMed Central: 3246859
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Primary cutaneous angiosarcoma of the breast after breast trauma</title><author><name sortKey="Cao, Ying" sort="Cao, Ying" uniqKey="Cao Y" first="Ying" last="Cao">Ying Cao</name></author><author><name sortKey="Panos, Laura" sort="Panos, Laura" uniqKey="Panos L" first="Laura" last="Panos">Laura Panos</name></author><author><name sortKey="Graham, Robbie L" sort="Graham, Robbie L" uniqKey="Graham R" first="Robbie L." last="Graham">Robbie L. Graham</name></author><author><name sortKey="Parker, Thornwell H" sort="Parker, Thornwell H" uniqKey="Parker T" first="Thornwell H." last="Parker">Thornwell H. Parker</name></author><author><name sortKey="Mennel, Robert" sort="Mennel, Robert" uniqKey="Mennel R" first="Robert" last="Mennel">Robert Mennel</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22275789</idno><idno type="pmc">3246859</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246859</idno><idno type="RBID">PMC:3246859</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">003154</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003154</idno><idno type="wicri:Area/Pmc/Curation">003153</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003153</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Primary cutaneous angiosarcoma of the breast after breast trauma</title><author><name sortKey="Cao, Ying" sort="Cao, Ying" uniqKey="Cao Y" first="Ying" last="Cao">Ying Cao</name></author><author><name sortKey="Panos, Laura" sort="Panos, Laura" uniqKey="Panos L" first="Laura" last="Panos">Laura Panos</name></author><author><name sortKey="Graham, Robbie L" sort="Graham, Robbie L" uniqKey="Graham R" first="Robbie L." last="Graham">Robbie L. Graham</name></author><author><name sortKey="Parker, Thornwell H" sort="Parker, Thornwell H" uniqKey="Parker T" first="Thornwell H." last="Parker">Thornwell H. Parker</name></author><author><name sortKey="Mennel, Robert" sort="Mennel, Robert" uniqKey="Mennel R" first="Robert" last="Mennel">Robert Mennel</name></author></analytic><series><title level="j">Proceedings (Baylor University. Medical Center)</title><idno type="ISSN">0899-8280</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Primary angiosarcoma of the breast is a rare malignant tumor. We report a case of breast primary cutaneous angiosarcoma in a patient with a strong family history of malignancy. For definitive diagnosis, a tissue biopsy is needed, with immunostaining for the presence of blood vessel endothelial markers CD31 and CD34. Total mastectomy is the preferred method of surgical treatment. Chemotherapy has not been shown to increase overall survival, but in some instances it may improve local control and disease-free survival. Surgery combined with radiation may increase local control, but patients at high risk of recurrence may benefit from adjuvant treatment as well. We discuss the potential benefits from various treatments for primary cutaneous breast angiosarcoma.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Proc (Bayl Univ Med Cent)</journal-id><journal-id journal-id-type="publisher-id">bumc</journal-id><journal-title-group><journal-title>Proceedings (Baylor University. Medical Center)</journal-title></journal-title-group><issn pub-type="ppub">0899-8280</issn><publisher><publisher-name>Baylor Health Care System</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22275789</article-id><article-id pub-id-type="pmc">3246859</article-id><article-id pub-id-type="publisher-id">bumc0025-0070</article-id><article-categories><subj-group subj-group-type="heading"><subject>Departments</subject><subj-group><subject>Baylor Sammons Cancer Center at Dallas Site Tumor Conference</subject></subj-group></subj-group></article-categories><title-group><article-title>Primary cutaneous angiosarcoma of the breast after breast trauma</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Cao</surname><given-names>Ying</given-names></name><degrees>MD, PhD</degrees></contrib><contrib contrib-type="author"><name><surname>Panos</surname><given-names>Laura</given-names></name><degrees>MS, CGC</degrees></contrib><contrib contrib-type="author"><name><surname>Graham</surname><given-names>Robbie L.</given-names></name><degrees>MD</degrees></contrib><contrib contrib-type="author"><name><surname>Parker</surname><given-names>Thornwell H.</given-names><suffix>III</suffix></name><degrees>MD</degrees></contrib><contrib contrib-type="author"><name><surname>Mennel</surname><given-names>Robert</given-names></name><degrees>MD</degrees></contrib></contrib-group><aff>From the Departments of Oncology (Cao, Panos, Mennel) and Pathology (Graham), Baylor Charles A. Sammons Cancer Center and Baylor University Medical Center at Dallas; and Skin Cancer Consultants, Dallas, Texas (Parker).</aff><author-notes><corresp><bold>Corresponding author:</bold> Ying Cao, MD, Fellow, Department of Oncology, Baylor Sammons Cancer Center at Baylor University Medical Center at Dallas, 3410 Worth Street, Dallas, Texas 75246 (e-mail: <email>Ying.Cao@BaylorHealth.edu</email>).</corresp></author-notes><pub-date pub-type="ppub"><month>1</month><year>2012</year></pub-date><volume>25</volume><issue>1</issue><fpage>70</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright © 2012, Baylor University Medical Center</copyright-statement><copyright-year>2012</copyright-year></permissions><abstract><p>Primary angiosarcoma of the breast is a rare malignant tumor. We report a case of breast primary cutaneous angiosarcoma in a patient with a strong family history of malignancy. For definitive diagnosis, a tissue biopsy is needed, with immunostaining for the presence of blood vessel endothelial markers CD31 and CD34. Total mastectomy is the preferred method of surgical treatment. Chemotherapy has not been shown to increase overall survival, but in some instances it may improve local control and disease-free survival. Surgery combined with radiation may increase local control, but patients at high risk of recurrence may benefit from adjuvant treatment as well. We discuss the potential benefits from various treatments for primary cutaneous breast angiosarcoma.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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