Feasibility study of axillary reverse mapping lymphoscintigraphy in carcinoma breast: A concept toward preventing lymphedema
Identifieur interne : 001063 ( Main/Merge ); précédent : 001062; suivant : 001064Feasibility study of axillary reverse mapping lymphoscintigraphy in carcinoma breast: A concept toward preventing lymphedema
Auteurs : Sunny J. Gandhi [Inde] ; C. Satish [Inde] ; Palaniswamy Shanmuga Sundaram [Inde] ; Padma Subramanyam [Inde] ; D. K. Vijaykumar [Inde]Source :
- Indian Journal of Nuclear Medicine : IJNM : The Official Journal of the Society of Nuclear Medicine, India [ 0972-3919 ] ; 2016.
Abstract
In the surgery of breast cancer, axillary reverse mapping (ARM) is the identification and preservation of arm draining lymph node (ARM node) during an axillary dissection. The assumption is that the ARM node is different from node draining breast and is unlikely to be involved even in the patients with axillary nodal metastases. If we can identify and preserve ARM node using lymphoscintigraphy; morbidity of lymphedema, as seen with axillary dissection, may be avoided.
Pathologically proven 50 breast cancer patients undergoing initial surgery (cTx-4, cN0-2, and Mx-0) were included in this study. Less than 37 MBq, 0.5 ml in equally divided doses of filtered 99mTc sulfur colloid was injected intradermally into the second and third web spaces. ARM nodes in the axilla were identified with the help of Gamma Probe intraoperatively; however, their location was noted with the reference to specific anatomical landmarks and sent for histopathological examination after excision.
The ARM node was successfully identified in 47/50 cases (sensitivity - 94%). In 40 out of 47 cases (85%), the location of the ARM node was found to lateral to the subscapular pedicle, above the second intercostobrachial nerve and just below the axillary vein. Of the 47 patients in whom ARM node/s were identified, metastasis was noted in 5 of them (10%). Four out of these 5 patients had the pN3 disease.
ARM node exists, and it is feasible to identify ARM node using radio isotope technique with an excellent sensitivity. ARM node seems to have a fairly constant location in more than 80% cases. It is involved with metastasis (10% cases) only when there are multiple lymph nodal metastases in the axilla.
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DOI: 10.4103/0972-3919.172341
PubMed: 26917887
PubMed Central: 4746858
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Feasibility study of axillary reverse mapping lymphoscintigraphy in carcinoma breast: A concept toward preventing lymphedema</title>
<author><name sortKey="Gandhi, Sunny J" sort="Gandhi, Sunny J" uniqKey="Gandhi S" first="Sunny J." last="Gandhi">Sunny J. Gandhi</name>
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<series><title level="j">Indian Journal of Nuclear Medicine : IJNM : The Official Journal of the Society of Nuclear Medicine, India</title>
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<front><div type="abstract" xml:lang="en"><sec id="st1"><title>Objective:</title>
<p>In the surgery of breast cancer, axillary reverse mapping (ARM) is the identification and preservation of arm draining lymph node (ARM node) during an axillary dissection. The assumption is that the ARM node is different from node draining breast and is unlikely to be involved even in the patients with axillary nodal metastases. If we can identify and preserve ARM node using lymphoscintigraphy; morbidity of lymphedema, as seen with axillary dissection, may be avoided.</p>
</sec>
<sec id="st2"><title>Materials and Methods:</title>
<p>Pathologically proven 50 breast cancer patients undergoing initial surgery (cTx-4, cN0-2, and Mx-0) were included in this study. Less than 37 MBq, 0.5 ml in equally divided doses of filtered 99mTc sulfur colloid was injected intradermally into the second and third web spaces. ARM nodes in the axilla were identified with the help of Gamma Probe intraoperatively; however, their location was noted with the reference to specific anatomical landmarks and sent for histopathological examination after excision.</p>
</sec>
<sec id="st3"><title>Results:</title>
<p>The ARM node was successfully identified in 47/50 cases (sensitivity - 94%). In 40 out of 47 cases (85%), the location of the ARM node was found to lateral to the subscapular pedicle, above the second intercostobrachial nerve and just below the axillary vein. Of the 47 patients in whom ARM node/s were identified, metastasis was noted in 5 of them (10%). Four out of these 5 patients had the pN3 disease.</p>
</sec>
<sec id="st4"><title>Conclusion:</title>
<p>ARM node exists, and it is feasible to identify ARM node using radio isotope technique with an excellent sensitivity. ARM node seems to have a fairly constant location in more than 80% cases. It is involved with metastasis (10% cases) only when there are multiple lymph nodal metastases in the axilla.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Schrenk, P" uniqKey="Schrenk P">P Schrenk</name>
</author>
<author><name sortKey="Rieger, R" uniqKey="Rieger R">R Rieger</name>
</author>
<author><name sortKey="Shamiyeh, A" uniqKey="Shamiyeh A">A Shamiyeh</name>
</author>
<author><name sortKey="Wayand, W" uniqKey="Wayand W">W Wayand</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Haid, A" uniqKey="Haid A">A Haid</name>
</author>
<author><name sortKey="Koberle Wuhrer, R" uniqKey="Koberle Wuhrer R">R Köberle-Wührer</name>
</author>
<author><name sortKey="Knauer, M" uniqKey="Knauer M">M Knauer</name>
</author>
<author><name sortKey="Burtscher, J" uniqKey="Burtscher J">J Burtscher</name>
</author>
<author><name sortKey="Fritzsche, H" uniqKey="Fritzsche H">H Fritzsche</name>
</author>
<author><name sortKey="Peschina, W" uniqKey="Peschina W">W Peschina</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Swenson, Kk" uniqKey="Swenson K">KK Swenson</name>
</author>
<author><name sortKey="Nissen, Mj" uniqKey="Nissen M">MJ Nissen</name>
</author>
<author><name sortKey="Ceronsky, C" uniqKey="Ceronsky C">C Ceronsky</name>
</author>
<author><name sortKey="Swenson, L" uniqKey="Swenson L">L Swenson</name>
</author>
<author><name sortKey="Lee, Mw" uniqKey="Lee M">MW Lee</name>
</author>
<author><name sortKey="Tuttle, Tm" uniqKey="Tuttle T">TM Tuttle</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Blanchard, Dk" uniqKey="Blanchard D">DK Blanchard</name>
</author>
<author><name sortKey="Donohue, Jh" uniqKey="Donohue J">JH Donohue</name>
</author>
<author><name sortKey="Reynolds, C" uniqKey="Reynolds C">C Reynolds</name>
</author>
<author><name sortKey="Grant, Cs" uniqKey="Grant C">CS Grant</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schijven, Mp" uniqKey="Schijven M">MP Schijven</name>
</author>
<author><name sortKey="Vingerhoets, Aj" uniqKey="Vingerhoets A">AJ Vingerhoets</name>
</author>
<author><name sortKey="Rutten, Hj" uniqKey="Rutten H">HJ Rutten</name>
</author>
<author><name sortKey="Nieuwenhuijzen, Ga" uniqKey="Nieuwenhuijzen G">GA Nieuwenhuijzen</name>
</author>
<author><name sortKey="Roumen, Rm" uniqKey="Roumen R">RM Roumen</name>
</author>
<author><name sortKey="Van Bussel, Me" uniqKey="Van Bussel M">ME van Bussel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ronk, R" uniqKey="Ronk R">R Rönkä</name>
</author>
<author><name sortKey="Von Smitten, K" uniqKey="Von Smitten K">K von Smitten</name>
</author>
<author><name sortKey="Tasmuth, T" uniqKey="Tasmuth T">T Tasmuth</name>
</author>
<author><name sortKey="Leidenius, M" uniqKey="Leidenius M">M Leidenius</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Leidenius, M" uniqKey="Leidenius M">M Leidenius</name>
</author>
<author><name sortKey="Leivonen, M" uniqKey="Leivonen M">M Leivonen</name>
</author>
<author><name sortKey="Vironen, J" uniqKey="Vironen J">J Vironen</name>
</author>
<author><name sortKey="Von Smitten, K" uniqKey="Von Smitten K">K von Smitten</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Boneti, C" uniqKey="Boneti C">C Boneti</name>
</author>
<author><name sortKey="Korourian, S" uniqKey="Korourian S">S Korourian</name>
</author>
<author><name sortKey="Bland, K" uniqKey="Bland K">K Bland</name>
</author>
<author><name sortKey="Cox, K" uniqKey="Cox K">K Cox</name>
</author>
<author><name sortKey="Adkins, Ll" uniqKey="Adkins L">LL Adkins</name>
</author>
<author><name sortKey="Henry Tillman, Rs" uniqKey="Henry Tillman R">RS Henry-Tillman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sappey, Pc" uniqKey="Sappey P">PC Sappey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Delamere, G" uniqKey="Delamere G">G Delamere</name>
</author>
<author><name sortKey="Poirier, P" uniqKey="Poirier P">P Poirier</name>
</author>
<author><name sortKey="Cuneo, B" uniqKey="Cuneo B">B Cuneo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rouviere, H" uniqKey="Rouviere H">H Rouviere</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Turner Warwick, Rt" uniqKey="Turner Warwick R">RT Turner-Warwick</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sobotta, J" uniqKey="Sobotta J">J Sobotta</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Suami, H" uniqKey="Suami H">H Suami</name>
</author>
<author><name sortKey="Taylor, Gi" uniqKey="Taylor G">GI Taylor</name>
</author>
<author><name sortKey="Pan, Wr" uniqKey="Pan W">WR Pan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nos, C" uniqKey="Nos C">C Nos</name>
</author>
<author><name sortKey="Kaufmann, G" uniqKey="Kaufmann G">G Kaufmann</name>
</author>
<author><name sortKey="Clough, Kb" uniqKey="Clough K">KB Clough</name>
</author>
<author><name sortKey="Collignon, Ma" uniqKey="Collignon M">MA Collignon</name>
</author>
<author><name sortKey="Zerbib, E" uniqKey="Zerbib E">E Zerbib</name>
</author>
<author><name sortKey="Cusumano, P" uniqKey="Cusumano P">P Cusumano</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Thompson, M" uniqKey="Thompson M">M Thompson</name>
</author>
<author><name sortKey="Korourian, S" uniqKey="Korourian S">S Korourian</name>
</author>
<author><name sortKey="Henry Tillman, R" uniqKey="Henry Tillman R">R Henry-Tillman</name>
</author>
<author><name sortKey="Adkins, L" uniqKey="Adkins L">L Adkins</name>
</author>
<author><name sortKey="Mumford, S" uniqKey="Mumford S">S Mumford</name>
</author>
<author><name sortKey="Westbrook, Kc" uniqKey="Westbrook K">KC Westbrook</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Casabona, F" uniqKey="Casabona F">F Casabona</name>
</author>
<author><name sortKey="Bogliolo, S" uniqKey="Bogliolo S">S Bogliolo</name>
</author>
<author><name sortKey="Valenzano Menada, M" uniqKey="Valenzano Menada M">M Valenzano Menada</name>
</author>
<author><name sortKey="Sala, P" uniqKey="Sala P">P Sala</name>
</author>
<author><name sortKey="Villa, G" uniqKey="Villa G">G Villa</name>
</author>
<author><name sortKey="Ferrero, S" uniqKey="Ferrero S">S Ferrero</name>
</author>
</analytic>
</biblStruct>
</listBibl>
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