Surgical staging in carcinoma of the prostate: The RTOG experience
Identifieur interne : 00F200 ( Main/Exploration ); précédent : 00F199; suivant : 00F201Surgical staging in carcinoma of the prostate: The RTOG experience
Auteurs : M. V. Pilepich ; S. O. Asbell [États-Unis] ; G. S. Mulholland [États-Unis] ; T. Pajak [États-Unis]Source :
- The Prostate [ 0270-4137 ] ; 1984.
Descripteurs français
- KwdFr :
- Attribution aléatoire, Biopsie, Carcinomes (), Carcinomes (anatomopathologie), Carcinomes (radiothérapie), Dosimétrie en radiothérapie, Humains, Lymphadénectomie, Lymphoedème (épidémiologie), Mâle, Métastase lymphatique, Noeuds lymphatiques (anatomopathologie), Stade de la tumeur, Tumeurs de la prostate (), Tumeurs de la prostate (anatomopathologie), Tumeurs de la prostate (radiothérapie), Études de suivi.
- MESH :
- anatomopathologie : Carcinomes, Noeuds lymphatiques, Tumeurs de la prostate.
- radiothérapie : Carcinomes, Tumeurs de la prostate.
- épidémiologie : Lymphoedème.
- Attribution aléatoire, Biopsie, Carcinomes, Dosimétrie en radiothérapie, Humains, Lymphadénectomie, Mâle, Métastase lymphatique, Stade de la tumeur, Tumeurs de la prostate, Études de suivi.
English descriptors
- KwdEn :
- Biopsy, Carcinoma (pathology), Carcinoma (radiotherapy), Carcinoma (surgery), Follow-Up Studies, Humans, Lymph Node Excision, Lymph Nodes (pathology), Lymphatic Metastasis, Lymphedema (epidemiology), Male, Neoplasm Staging, Prostatic Neoplasms (pathology), Prostatic Neoplasms (radiotherapy), Prostatic Neoplasms (surgery), Radiotherapy Dosage, Random Allocation.
- MESH :
- epidemiology : Lymphedema.
- pathology : Carcinoma, Lymph Nodes, Prostatic Neoplasms.
- radiotherapy : Carcinoma, Prostatic Neoplasms.
- surgery : Carcinoma, Prostatic Neoplasms.
- Biopsy, Follow-Up Studies, Humans, Lymph Node Excision, Lymphatic Metastasis, Male, Neoplasm Staging, Radiotherapy Dosage, Random Allocation.
Abstract
One hundred thirty‐six patients with carcinoma of the prostate entered on phase III RTOG studies (RTOG 75–06 and RTOG 77–06) between 1976 and the end of 1980 underwent staging lymphadenectomy prior to irradiation. The operative reports and histological findings have been reviewed in order to determine the patterns of intrapelvic tumor spread and to correlate the type of surgical procedure and the extent of lymphatic dissection with the incidence and type of postirradiation complications (primarily genital and lower extremity lymphedema). The surgical procedures were classified into three categories according to extent: 1) biopsy only, 2) limited (diagnostic) dissection, and 3) complete (therapeutic) dissection. The incidence of postirradiation lymphedema was found to be strongly dependent upon the extent of dissection. Patients undergoing limited (diagnostic) dissection followed by pelvic irradiation have a 25–30% risk of developing this debilitating complication. In patients undergoing complete (therapeutic) dissection followed by pelvic irradiation lymphedema has been observed in 66% of cases.
Url:
DOI: 10.1002/pros.2990050502
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">One hundred thirty‐six patients with carcinoma of the prostate entered on phase III RTOG studies (RTOG 75–06 and RTOG 77–06) between 1976 and the end of 1980 underwent staging lymphadenectomy prior to irradiation. The operative reports and histological findings have been reviewed in order to determine the patterns of intrapelvic tumor spread and to correlate the type of surgical procedure and the extent of lymphatic dissection with the incidence and type of postirradiation complications (primarily genital and lower extremity lymphedema). The surgical procedures were classified into three categories according to extent: 1) biopsy only, 2) limited (diagnostic) dissection, and 3) complete (therapeutic) dissection. The incidence of postirradiation lymphedema was found to be strongly dependent upon the extent of dissection. Patients undergoing limited (diagnostic) dissection followed by pelvic irradiation have a 25–30% risk of developing this debilitating complication. In patients undergoing complete (therapeutic) dissection followed by pelvic irradiation lymphedema has been observed in 66% of cases.</div>
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