Surgical staging in carcinoma of the prostate: The RTOG experience
Identifieur interne : 010066 ( Main/Merge ); précédent : 010065; suivant : 010067Surgical staging in carcinoma of the prostate: The RTOG experience
Auteurs : M. V. Pilepich ; S. O. Asbell [États-Unis] ; G. S. Mulholland [États-Unis] ; T. Pajak [États-Unis]Source :
- The Prostate [ 0270-4137 ] ; 1984.
Abstract
One hundred thirty‐six patients with carcinoma of the prostate entered on phase III RTOG studies (RTOG 75–06 and RTOG 77–06) between 1976 and the end of 1980 underwent staging lymphadenectomy prior to irradiation. The operative reports and histological findings have been reviewed in order to determine the patterns of intrapelvic tumor spread and to correlate the type of surgical procedure and the extent of lymphatic dissection with the incidence and type of postirradiation complications (primarily genital and lower extremity lymphedema). The surgical procedures were classified into three categories according to extent: 1) biopsy only, 2) limited (diagnostic) dissection, and 3) complete (therapeutic) dissection. The incidence of postirradiation lymphedema was found to be strongly dependent upon the extent of dissection. Patients undergoing limited (diagnostic) dissection followed by pelvic irradiation have a 25–30% risk of developing this debilitating complication. In patients undergoing complete (therapeutic) dissection followed by pelvic irradiation lymphedema has been observed in 66% of cases.
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DOI: 10.1002/pros.2990050502
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Pajak</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">Philadelphie</settlement><region type="state">Pennsylvanie</region></placeName><wicri:orgArea>RTOG Headquarters</wicri:orgArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">The Prostate</title><title level="j" type="alt">PROSTATE, THE</title><idno type="ISSN">0270-4137</idno><idno type="eISSN">1097-0045</idno><imprint><biblScope unit="vol">5</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="471">471</biblScope><biblScope unit="page" to="476">476</biblScope><biblScope unit="page-count">6</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="1984">1984</date></imprint><idno type="ISSN">0270-4137</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0270-4137</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">One hundred thirty‐six patients with carcinoma of the prostate entered on phase III RTOG studies (RTOG 75–06 and RTOG 77–06) between 1976 and the end of 1980 underwent staging lymphadenectomy prior to irradiation. The operative reports and histological findings have been reviewed in order to determine the patterns of intrapelvic tumor spread and to correlate the type of surgical procedure and the extent of lymphatic dissection with the incidence and type of postirradiation complications (primarily genital and lower extremity lymphedema). The surgical procedures were classified into three categories according to extent: 1) biopsy only, 2) limited (diagnostic) dissection, and 3) complete (therapeutic) dissection. The incidence of postirradiation lymphedema was found to be strongly dependent upon the extent of dissection. Patients undergoing limited (diagnostic) dissection followed by pelvic irradiation have a 25–30% risk of developing this debilitating complication. In patients undergoing complete (therapeutic) dissection followed by pelvic irradiation lymphedema has been observed in 66% of cases.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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