Immunodiagnosis of bancroftian filariasis.
Identifieur interne : 00DA14 ( Main/Exploration ); précédent : 00DA13; suivant : 00DA15Immunodiagnosis of bancroftian filariasis.
Auteurs : S A Romia [Égypte] ; A A Abou-Zakham ; H. Rezk ; A F Abou-ShadySource :
- Journal of the Egyptian Society of Parasitology [ 1110-0583 ] ; 1990.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Animaux, Anticorps antihelminthe (analyse), Filariose lymphatique (diagnostic), Filarioses (diagnostic), Humains, Technique d'immunofluorescence, Test ELISA, Tests d'hémagglutination, Valeur prédictive des tests, Wuchereria (immunologie), Wuchereria bancrofti (immunologie).
- MESH :
- analyse : Anticorps antihelminthe.
- diagnostic : Filariose lymphatique, Filarioses.
- immunologie : Wuchereria, Wuchereria bancrofti.
- Adulte, Adulte d'âge moyen, Animaux, Humains, Technique d'immunofluorescence, Test ELISA, Tests d'hémagglutination, Valeur prédictive des tests.
English descriptors
- KwdEn :
- Adult, Animals, Antibodies, Helminth (analysis), Elephantiasis, Filarial (diagnosis), Enzyme-Linked Immunosorbent Assay, Filariasis (diagnosis), Fluorescent Antibody Technique, Hemagglutination Tests, Humans, Middle Aged, Predictive Value of Tests, Wuchereria (immunology), Wuchereria bancrofti (immunology).
- MESH :
- chemical , analysis : Antibodies, Helminth.
- diagnosis : Elephantiasis, Filarial, Filariasis.
- immunology : Wuchereria, Wuchereria bancrofti.
- Adult, Animals, Enzyme-Linked Immunosorbent Assay, Fluorescent Antibody Technique, Hemagglutination Tests, Humans, Middle Aged, Predictive Value of Tests.
Abstract
The indirect fluorescent antibody test, the enzyme-linked immuno sorbent assay and the indirect haemagglutination test were evaluated in immunodiagnosis of bancroftian filariasis using W. bancrofti microfilarial antigens. The tests gave a higher positive reactions with microfilaraemic, clinical filarial and endemic normal sera respectively. Non-specific cross-reactions were common in the three tests, so immunodiagnosis should be preceded by stool examination. IFAT gave the highest sensitivity and specificity, while IHAT was the least one. ELISA is simple, sensitive and can be used in seroepidemiological studies.
PubMed: 2185319
Affiliations:
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Le document en format XML
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<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Filariasis (diagnosis)</term>
<term>Fluorescent Antibody Technique</term>
<term>Hemagglutination Tests</term>
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<term>Middle Aged</term>
<term>Predictive Value of Tests</term>
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<term>Anticorps antihelminthe (analyse)</term>
<term>Filariose lymphatique (diagnostic)</term>
<term>Filarioses (diagnostic)</term>
<term>Humains</term>
<term>Technique d'immunofluorescence</term>
<term>Test ELISA</term>
<term>Tests d'hémagglutination</term>
<term>Valeur prédictive des tests</term>
<term>Wuchereria (immunologie)</term>
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<term>Predictive Value of Tests</term>
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<term>Humains</term>
<term>Technique d'immunofluorescence</term>
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<term>Tests d'hémagglutination</term>
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<front><div type="abstract" xml:lang="en">The indirect fluorescent antibody test, the enzyme-linked immuno sorbent assay and the indirect haemagglutination test were evaluated in immunodiagnosis of bancroftian filariasis using W. bancrofti microfilarial antigens. The tests gave a higher positive reactions with microfilaraemic, clinical filarial and endemic normal sera respectively. Non-specific cross-reactions were common in the three tests, so immunodiagnosis should be preceded by stool examination. IFAT gave the highest sensitivity and specificity, while IHAT was the least one. ELISA is simple, sensitive and can be used in seroepidemiological studies.</div>
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