Prostaglandins, rheumatoid arthritis, fibrin and lymphoedema.
Identifieur interne : 00FC79 ( Main/Exploration ); précédent : 00FC78; suivant : 00FC80Prostaglandins, rheumatoid arthritis, fibrin and lymphoedema.
Auteurs : M K Jasani ; C S BachSource :
- Agents and actions. Supplements [ 0379-0363 ] ; 1979.
Descripteurs français
- KwdFr :
- Animaux, Anti-inflammatoires (pharmacologie), Fibrine (physiologie), Indométacine (pharmacologie), Inhibiteurs des cyclooxygénases, Lapins, Lymphocytes (), Lymphocytes (physiologie), Lymphoedème (physiopathologie), Polyarthrite rhumatoïde (physiopathologie), Prostaglandines (physiologie), Transplantation de peau, Transplantation homologue.
- MESH :
- pharmacologie : Anti-inflammatoires, Indométacine.
- physiologie : Fibrine, Lymphocytes, Prostaglandines.
- physiopathologie : Lymphoedème, Polyarthrite rhumatoïde.
- Animaux, Inhibiteurs des cyclooxygénases, Lapins, Lymphocytes, Transplantation de peau, Transplantation homologue.
English descriptors
- KwdEn :
- Animals, Anti-Inflammatory Agents (pharmacology), Arthritis, Rheumatoid (physiopathology), Cyclooxygenase Inhibitors, Fibrin (physiology), Indomethacin (pharmacology), Lymphedema (physiopathology), Lymphocytes (drug effects), Lymphocytes (physiology), Prostaglandins (physiology), Rabbits, Skin Transplantation, Transplantation, Homologous.
- MESH :
- chemical , pharmacology : Anti-Inflammatory Agents, Indomethacin.
- chemical , physiology : Fibrin, Prostaglandins.
- drug effects : Lymphocytes.
- physiology : Lymphocytes.
- physiopathology : Arthritis, Rheumatoid, Lymphedema.
- Animals, Cyclooxygenase Inhibitors, Rabbits, Skin Transplantation, Transplantation, Homologous.
Abstract
Rheumatoid joint swelling is in part due to lymphoedema accompanying extravascular (E-V) deposition of fibrin. Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin (ASA), phenylbutazone (PBZ) and indomethacin (INDO) which share the ability to inhibit prostaglandin synthetase fail to prevent fibrinous lymphoedema occurring in rabbit skin homografts in association with the presence of sensitised lymphocytes. The data highlight the need to define whether or not prostaglandins promote lymphocytic fibrinous lymphoedema.
PubMed: 115258
Affiliations:
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Le document en format XML
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<term>Anti-Inflammatory Agents (pharmacology)</term>
<term>Arthritis, Rheumatoid (physiopathology)</term>
<term>Cyclooxygenase Inhibitors</term>
<term>Fibrin (physiology)</term>
<term>Indomethacin (pharmacology)</term>
<term>Lymphedema (physiopathology)</term>
<term>Lymphocytes (drug effects)</term>
<term>Lymphocytes (physiology)</term>
<term>Prostaglandins (physiology)</term>
<term>Rabbits</term>
<term>Skin Transplantation</term>
<term>Transplantation, Homologous</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Anti-inflammatoires (pharmacologie)</term>
<term>Fibrine (physiologie)</term>
<term>Indométacine (pharmacologie)</term>
<term>Inhibiteurs des cyclooxygénases</term>
<term>Lapins</term>
<term>Lymphocytes ()</term>
<term>Lymphocytes (physiologie)</term>
<term>Lymphoedème (physiopathologie)</term>
<term>Polyarthrite rhumatoïde (physiopathologie)</term>
<term>Prostaglandines (physiologie)</term>
<term>Transplantation de peau</term>
<term>Transplantation homologue</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Inflammatory Agents</term>
<term>Indomethacin</term>
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<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Fibrin</term>
<term>Prostaglandins</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Lymphocytes</term>
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<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Anti-inflammatoires</term>
<term>Indométacine</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Fibrine</term>
<term>Lymphocytes</term>
<term>Prostaglandines</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Lymphocytes</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Lymphoedème</term>
<term>Polyarthrite rhumatoïde</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Arthritis, Rheumatoid</term>
<term>Lymphedema</term>
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<term>Cyclooxygenase Inhibitors</term>
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<term>Transplantation, Homologous</term>
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<term>Inhibiteurs des cyclooxygénases</term>
<term>Lapins</term>
<term>Lymphocytes</term>
<term>Transplantation de peau</term>
<term>Transplantation homologue</term>
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<front><div type="abstract" xml:lang="en">Rheumatoid joint swelling is in part due to lymphoedema accompanying extravascular (E-V) deposition of fibrin. Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin (ASA), phenylbutazone (PBZ) and indomethacin (INDO) which share the ability to inhibit prostaglandin synthetase fail to prevent fibrinous lymphoedema occurring in rabbit skin homografts in association with the presence of sensitised lymphocytes. The data highlight the need to define whether or not prostaglandins promote lymphocytic fibrinous lymphoedema.</div>
</front>
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<name sortKey="Jasani, M K" sort="Jasani, M K" uniqKey="Jasani M" first="M K" last="Jasani">M K Jasani</name>
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