Bacteriological studies of blood, tissue fluid, lymph and lymph nodes in patients with acute dermatolymphangioadenitis (DLA) in course of ‘filarial’ lymphedema
Identifieur interne : 00AF20 ( Main/Exploration ); précédent : 00AF19; suivant : 00AF21Bacteriological studies of blood, tissue fluid, lymph and lymph nodes in patients with acute dermatolymphangioadenitis (DLA) in course of ‘filarial’ lymphedema
Auteurs : W. L Olszewski [Pologne] ; S. Jamal [Inde] ; G. Manokaran [Inde] ; S. Pani [Inde] ; V. Kumaraswami [Inde] ; U. Kubicka [Pologne] ; B. Lukomska [Pologne] ; F. M Tripathi [Inde] ; E. Swoboda [Pologne] ; F. Meisel-Mikolajczyk [Pologne] ; E. Stelmach [Pologne] ; M. Zaleska [Pologne]Source :
- Acta Tropica [ 0001-706X ] ; 1999.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Bactéries (), Bactéries (isolement et purification), Bactéries à Gram négatif (), Bactéries à Gram négatif (isolement et purification), Bactéries à Gram positif (), Bactéries à Gram positif (isolement et purification), Bactériémie (), Bactériémie (microbiologie), Biopsie, Femelle, Filariose lymphatique (), Filariose lymphatique (microbiologie), Humains, Liquides biologiques (microbiologie), Lymphadénite (microbiologie), Lymphangite (microbiologie), Lymphe (microbiologie), Mâle, Noeuds lymphatiques (microbiologie), Peau (microbiologie).
- MESH :
- isolement et purification : Bactéries, Bactéries à Gram négatif, Bactéries à Gram positif.
- microbiologie : Bactériémie, Filariose lymphatique, Liquides biologiques, Lymphadénite, Lymphangite, Lymphe, Noeuds lymphatiques, Peau.
- Pascal (Inist)
- Wicri :
- geographic : Inde.
- topic : Association, Homme.
English descriptors
- KwdEn :
- Adenopathy, Adolescent, Adult, Association, Bacteremia (complications), Bacteremia (microbiology), Bacteria, Bacteria (classification), Bacteria (isolation & purification), Bacteriological investigation, Biopsy, Body Fluids (microbiology), Elephantiasis, Filarial (complications), Elephantiasis, Filarial (microbiology), Female, Filarial fever, Filariosis, Gram-Negative Bacteria (classification), Gram-Negative Bacteria (isolation & purification), Gram-Positive Bacteria (classification), Gram-Positive Bacteria (isolation & purification), Human, Humans, India, Lymph, Lymph (microbiology), Lymph Nodes (microbiology), Lymphadenitis (microbiology), Lymphangitis (microbiology), Lymphedema, Male, Middle Aged, Prevalence, Skin (microbiology).
- MESH :
- classification : Bacteria, Gram-Negative Bacteria, Gram-Positive Bacteria.
- complications : Bacteremia, Elephantiasis, Filarial.
- isolation & purification : Bacteria, Gram-Negative Bacteria, Gram-Positive Bacteria.
- microbiology : Bacteremia, Body Fluids, Elephantiasis, Filarial, Lymph, Lymph Nodes, Lymphadenitis, Lymphangitis, Skin.
- Adolescent, Adult, Biopsy, Female, Humans, Male, Middle Aged.
Abstract
Filarial lymphedema is complicated by frequent episodes of dermatolymphangioadenitis (DLA). Severe systemic symptoms during attacks of DLA resemble those of septicemia. The question we asked was whether bacterial isolates can be found in the peripheral blood of patients during the episodes of DLA. Out of 100 patients referred to us with ‘filarial’ lymphedema 14 displayed acute and five subacute symptoms of DLA. All were on admission blood microfilariae negative but had a positive test in the past. Blood bacterial isolates were found in nine cases, four acute (21%) and five subacute (26%). In 10 acute cases blood cultures were found negative. Six blood isolates belonged to Bacilli, four to Cocci and one was Sarcina. To identify the sites of origin of bacterial dissemination, swabs taken from the calf skin biopsy wounds and tissue fluid, lymph and lymph node specimens were cultured. Swabs from the calf skin biopsy wound contained isolates in nine (47%) cases. They were Bacilli in nine, Cocci in three, Acinetobacter and Erwinia in two cases. Tissue fluid was collected from 10 patients and contained Bacilli in four (40%) and Staphylococci in three (30%). Lymph was drained in four patients and contained isolates in all samples (100%). They were Staphylococcusepidermis, xylosus and aureus, Acinetobacter, Bacillussubtilis and Sarcina. Three lymph nodes were biopsied and contained Staphylococcus chromogenes, xylosus, Enterococcus and Bacilluscereus. In six cases the same phenotypically defined species of bacteria were found in blood and limb tissues or fluids. In the ‘control’ group of patients with lymphedema without acute or subacute changes all blood cultures were negative. Interestingly, swabs from biopsy wound of these patients contained isolates in 80%, tissue fluid in 68%, lymph in 70% and lymph nodes in 58% of cases. In healthy controls, tissue fluid did not contain bacteria, and lymph isolates were found only in 12% of cases. This study demonstrates that patients with acute episodes of DLA reveal bacteriemia in a high percentage of cases. Diversity of blood and tissue bacterial isolates in these patients points to a breakdown of the skin immune barrier in lymphedema and subsequently indiscriminate bacterial colonization of deep tissues and spread to an blood circulation.
Url:
DOI: 10.1016/S0001-706X(99)00029-7
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 005C48
- to stream Istex, to step Curation: 005C48
- to stream Istex, to step Checkpoint: 003841
- to stream Main, to step Merge: 00B538
- to stream PascalFrancis, to step Corpus: 000959
- to stream PascalFrancis, to step Curation: 000001
- to stream PascalFrancis, to step Checkpoint: 000A09
- to stream Main, to step Merge: 00B651
- to stream PubMed, to step Corpus: 004B82
- to stream PubMed, to step Curation: 004B82
- to stream PubMed, to step Checkpoint: 004B82
- to stream Ncbi, to step Merge: 000207
- to stream Ncbi, to step Curation: 000207
- to stream Ncbi, to step Checkpoint: 000207
- to stream Main, to step Merge: 00B052
- to stream Main, to step Curation: 00AF20
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Bacteriological studies of blood, tissue fluid, lymph and lymph nodes in patients with acute dermatolymphangioadenitis (DLA) in course of ‘filarial’ lymphedema</title>
<author><name sortKey="Olszewski, W L" sort="Olszewski, W L" uniqKey="Olszewski W" first="W. L" last="Olszewski">W. L Olszewski</name>
</author>
<author><name sortKey="Jamal, S" sort="Jamal, S" uniqKey="Jamal S" first="S" last="Jamal">S. Jamal</name>
</author>
<author><name sortKey="Manokaran, G" sort="Manokaran, G" uniqKey="Manokaran G" first="G" last="Manokaran">G. Manokaran</name>
</author>
<author><name sortKey="Pani, S" sort="Pani, S" uniqKey="Pani S" first="S" last="Pani">S. Pani</name>
</author>
<author><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name>
</author>
<author><name sortKey="Kubicka, U" sort="Kubicka, U" uniqKey="Kubicka U" first="U" last="Kubicka">U. Kubicka</name>
</author>
<author><name sortKey="Lukomska, B" sort="Lukomska, B" uniqKey="Lukomska B" first="B" last="Lukomska">B. Lukomska</name>
</author>
<author><name sortKey="Tripathi, F M" sort="Tripathi, F M" uniqKey="Tripathi F" first="F. M" last="Tripathi">F. M Tripathi</name>
</author>
<author><name sortKey="Swoboda, E" sort="Swoboda, E" uniqKey="Swoboda E" first="E" last="Swoboda">E. Swoboda</name>
</author>
<author><name sortKey="Meisel Mikolajczyk, F" sort="Meisel Mikolajczyk, F" uniqKey="Meisel Mikolajczyk F" first="F" last="Meisel-Mikolajczyk">F. Meisel-Mikolajczyk</name>
</author>
<author><name sortKey="Stelmach, E" sort="Stelmach, E" uniqKey="Stelmach E" first="E" last="Stelmach">E. Stelmach</name>
</author>
<author><name sortKey="Zaleska, M" sort="Zaleska, M" uniqKey="Zaleska M" first="M" last="Zaleska">M. Zaleska</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:C535ADCA81C224AFC0F09C9E518132C914E3740A</idno>
<date when="1999" year="1999">1999</date>
<idno type="doi">10.1016/S0001-706X(99)00029-7</idno>
<idno type="url">https://api.istex.fr/document/C535ADCA81C224AFC0F09C9E518132C914E3740A/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">005C48</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">005C48</idno>
<idno type="wicri:Area/Istex/Curation">005C48</idno>
<idno type="wicri:Area/Istex/Checkpoint">003841</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">003841</idno>
<idno type="wicri:doubleKey">0001-706X:1999:Olszewski W:bacteriological:studies:of</idno>
<idno type="wicri:Area/Main/Merge">00B538</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:00-0017323</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000959</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000001</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000A09</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000A09</idno>
<idno type="wicri:doubleKey">0001-706X:1999:Olszewski W:bacteriological:studies:of</idno>
<idno type="wicri:Area/Main/Merge">00B651</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:10546838</idno>
<idno type="wicri:Area/PubMed/Corpus">004B82</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004B82</idno>
<idno type="wicri:Area/PubMed/Curation">004B82</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">004B82</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004B82</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">004B82</idno>
<idno type="wicri:Area/Ncbi/Merge">000207</idno>
<idno type="wicri:Area/Ncbi/Curation">000207</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000207</idno>
<idno type="wicri:doubleKey">0001-706X:1999:Olszewski W:bacteriological:studies:of</idno>
<idno type="wicri:Area/Main/Merge">00B052</idno>
<idno type="wicri:Area/Main/Curation">00AF20</idno>
<idno type="wicri:Area/Main/Exploration">00AF20</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Bacteriological studies of blood, tissue fluid, lymph and lymph nodes in patients with acute dermatolymphangioadenitis (DLA) in course of ‘filarial’ lymphedema</title>
<author><name sortKey="Olszewski, W L" sort="Olszewski, W L" uniqKey="Olszewski W" first="W. L" last="Olszewski">W. L Olszewski</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pologne</country>
<wicri:regionArea>The Norwegian Radium Hospital, Oslo, Norway and Department of Surgical Research, Medical Research Center, Polish Academy of Sciences, 5 Pawinski Str., 12106 Warsaw</wicri:regionArea>
<wicri:noRegion>12106 Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jamal, S" sort="Jamal, S" uniqKey="Jamal S" first="S" last="Jamal">S. Jamal</name>
<affiliation wicri:level="1"><country xml:lang="fr">Inde</country>
<wicri:regionArea>Thanjavur Medical College, Thanjavur</wicri:regionArea>
<wicri:noRegion>Thanjavur</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Manokaran, G" sort="Manokaran, G" uniqKey="Manokaran G" first="G" last="Manokaran">G. Manokaran</name>
<affiliation wicri:level="1"><country xml:lang="fr">Inde</country>
<wicri:regionArea>Apollo Hospitals, Madras</wicri:regionArea>
<wicri:noRegion>Madras</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pani, S" sort="Pani, S" uniqKey="Pani S" first="S" last="Pani">S. Pani</name>
<affiliation wicri:level="1"><country xml:lang="fr">Inde</country>
<wicri:regionArea>Vector Control Research Center, ICMR, Pondicherry</wicri:regionArea>
<wicri:noRegion>Pondicherry</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name>
<affiliation wicri:level="1"><country xml:lang="fr">Inde</country>
<wicri:regionArea>Tuberculosis Research Center, ICMR, Madras</wicri:regionArea>
<wicri:noRegion>Madras</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kubicka, U" sort="Kubicka, U" uniqKey="Kubicka U" first="U" last="Kubicka">U. Kubicka</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pologne</country>
<wicri:regionArea>The Norwegian Radium Hospital, Oslo, Norway and Department of Surgical Research, Medical Research Center, Polish Academy of Sciences, 5 Pawinski Str., 12106 Warsaw</wicri:regionArea>
<wicri:noRegion>12106 Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lukomska, B" sort="Lukomska, B" uniqKey="Lukomska B" first="B" last="Lukomska">B. Lukomska</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pologne</country>
<wicri:regionArea>The Norwegian Radium Hospital, Oslo, Norway and Department of Surgical Research, Medical Research Center, Polish Academy of Sciences, 5 Pawinski Str., 12106 Warsaw</wicri:regionArea>
<wicri:noRegion>12106 Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tripathi, F M" sort="Tripathi, F M" uniqKey="Tripathi F" first="F. M" last="Tripathi">F. M Tripathi</name>
<affiliation wicri:level="1"><country xml:lang="fr">Inde</country>
<wicri:regionArea>Banaras Hindu University, Varanasi</wicri:regionArea>
<wicri:noRegion>Varanasi</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Swoboda, E" sort="Swoboda, E" uniqKey="Swoboda E" first="E" last="Swoboda">E. Swoboda</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Clinical Bacteriology, Medical Academy, Warsaw</wicri:regionArea>
<wicri:noRegion>Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Meisel Mikolajczyk, F" sort="Meisel Mikolajczyk, F" uniqKey="Meisel Mikolajczyk F" first="F" last="Meisel-Mikolajczyk">F. Meisel-Mikolajczyk</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Clinical Bacteriology, Medical Academy, Warsaw</wicri:regionArea>
<wicri:noRegion>Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stelmach, E" sort="Stelmach, E" uniqKey="Stelmach E" first="E" last="Stelmach">E. Stelmach</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pologne</country>
<wicri:regionArea>The Norwegian Radium Hospital, Oslo, Norway and Department of Surgical Research, Medical Research Center, Polish Academy of Sciences, 5 Pawinski Str., 12106 Warsaw</wicri:regionArea>
<wicri:noRegion>12106 Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zaleska, M" sort="Zaleska, M" uniqKey="Zaleska M" first="M" last="Zaleska">M. Zaleska</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pologne</country>
<wicri:regionArea>The Norwegian Radium Hospital, Oslo, Norway and Department of Surgical Research, Medical Research Center, Polish Academy of Sciences, 5 Pawinski Str., 12106 Warsaw</wicri:regionArea>
<wicri:noRegion>12106 Warsaw</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Acta Tropica</title>
<title level="j" type="abbrev">ACTROP</title>
<idno type="ISSN">0001-706X</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="1999">1999</date>
<biblScope unit="volume">73</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="217">217</biblScope>
<biblScope unit="page" to="224">224</biblScope>
</imprint>
<idno type="ISSN">0001-706X</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0001-706X</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenopathy</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Association</term>
<term>Bacteremia (complications)</term>
<term>Bacteremia (microbiology)</term>
<term>Bacteria</term>
<term>Bacteria (classification)</term>
<term>Bacteria (isolation & purification)</term>
<term>Bacteriological investigation</term>
<term>Biopsy</term>
<term>Body Fluids (microbiology)</term>
<term>Elephantiasis, Filarial (complications)</term>
<term>Elephantiasis, Filarial (microbiology)</term>
<term>Female</term>
<term>Filarial fever</term>
<term>Filariosis</term>
<term>Gram-Negative Bacteria (classification)</term>
<term>Gram-Negative Bacteria (isolation & purification)</term>
<term>Gram-Positive Bacteria (classification)</term>
<term>Gram-Positive Bacteria (isolation & purification)</term>
<term>Human</term>
<term>Humans</term>
<term>India</term>
<term>Lymph</term>
<term>Lymph (microbiology)</term>
<term>Lymph Nodes (microbiology)</term>
<term>Lymphadenitis (microbiology)</term>
<term>Lymphangitis (microbiology)</term>
<term>Lymphedema</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prevalence</term>
<term>Skin (microbiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bactéries ()</term>
<term>Bactéries (isolement et purification)</term>
<term>Bactéries à Gram négatif ()</term>
<term>Bactéries à Gram négatif (isolement et purification)</term>
<term>Bactéries à Gram positif ()</term>
<term>Bactéries à Gram positif (isolement et purification)</term>
<term>Bactériémie ()</term>
<term>Bactériémie (microbiologie)</term>
<term>Biopsie</term>
<term>Femelle</term>
<term>Filariose lymphatique ()</term>
<term>Filariose lymphatique (microbiologie)</term>
<term>Humains</term>
<term>Liquides biologiques (microbiologie)</term>
<term>Lymphadénite (microbiologie)</term>
<term>Lymphangite (microbiologie)</term>
<term>Lymphe (microbiologie)</term>
<term>Mâle</term>
<term>Noeuds lymphatiques (microbiologie)</term>
<term>Peau (microbiologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Bacteria</term>
<term>Gram-Negative Bacteria</term>
<term>Gram-Positive Bacteria</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Bacteremia</term>
<term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Bacteria</term>
<term>Gram-Negative Bacteria</term>
<term>Gram-Positive Bacteria</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Bactéries</term>
<term>Bactéries à Gram négatif</term>
<term>Bactéries à Gram positif</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Bactériémie</term>
<term>Filariose lymphatique</term>
<term>Liquides biologiques</term>
<term>Lymphadénite</term>
<term>Lymphangite</term>
<term>Lymphe</term>
<term>Noeuds lymphatiques</term>
<term>Peau</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Bacteremia</term>
<term>Body Fluids</term>
<term>Elephantiasis, Filarial</term>
<term>Lymph</term>
<term>Lymph Nodes</term>
<term>Lymphadenitis</term>
<term>Lymphangitis</term>
<term>Skin</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Biopsy</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Adénopathie</term>
<term>Association</term>
<term>Bactéries</term>
<term>Bactéries à Gram négatif</term>
<term>Bactéries à Gram positif</term>
<term>Bactériémie</term>
<term>Biopsie</term>
<term>Exploration bactériologique</term>
<term>Femelle</term>
<term>Filariose</term>
<term>Filariose lymphatique</term>
<term>Homme</term>
<term>Humains</term>
<term>Inde</term>
<term>Lymphoedème</term>
<term>Mâle</term>
<term>Prévalence</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Inde</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Association</term>
<term>Homme</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Filarial lymphedema is complicated by frequent episodes of dermatolymphangioadenitis (DLA). Severe systemic symptoms during attacks of DLA resemble those of septicemia. The question we asked was whether bacterial isolates can be found in the peripheral blood of patients during the episodes of DLA. Out of 100 patients referred to us with ‘filarial’ lymphedema 14 displayed acute and five subacute symptoms of DLA. All were on admission blood microfilariae negative but had a positive test in the past. Blood bacterial isolates were found in nine cases, four acute (21%) and five subacute (26%). In 10 acute cases blood cultures were found negative. Six blood isolates belonged to Bacilli, four to Cocci and one was Sarcina. To identify the sites of origin of bacterial dissemination, swabs taken from the calf skin biopsy wounds and tissue fluid, lymph and lymph node specimens were cultured. Swabs from the calf skin biopsy wound contained isolates in nine (47%) cases. They were Bacilli in nine, Cocci in three, Acinetobacter and Erwinia in two cases. Tissue fluid was collected from 10 patients and contained Bacilli in four (40%) and Staphylococci in three (30%). Lymph was drained in four patients and contained isolates in all samples (100%). They were Staphylococcusepidermis, xylosus and aureus, Acinetobacter, Bacillussubtilis and Sarcina. Three lymph nodes were biopsied and contained Staphylococcus chromogenes, xylosus, Enterococcus and Bacilluscereus. In six cases the same phenotypically defined species of bacteria were found in blood and limb tissues or fluids. In the ‘control’ group of patients with lymphedema without acute or subacute changes all blood cultures were negative. Interestingly, swabs from biopsy wound of these patients contained isolates in 80%, tissue fluid in 68%, lymph in 70% and lymph nodes in 58% of cases. In healthy controls, tissue fluid did not contain bacteria, and lymph isolates were found only in 12% of cases. This study demonstrates that patients with acute episodes of DLA reveal bacteriemia in a high percentage of cases. Diversity of blood and tissue bacterial isolates in these patients points to a breakdown of the skin immune barrier in lymphedema and subsequently indiscriminate bacterial colonization of deep tissues and spread to an blood circulation.</div>
</front>
</TEI>
<affiliations><list><country><li>Inde</li>
<li>Pologne</li>
</country>
</list>
<tree><country name="Pologne"><noRegion><name sortKey="Olszewski, W L" sort="Olszewski, W L" uniqKey="Olszewski W" first="W. L" last="Olszewski">W. L Olszewski</name>
</noRegion>
<name sortKey="Kubicka, U" sort="Kubicka, U" uniqKey="Kubicka U" first="U" last="Kubicka">U. Kubicka</name>
<name sortKey="Lukomska, B" sort="Lukomska, B" uniqKey="Lukomska B" first="B" last="Lukomska">B. Lukomska</name>
<name sortKey="Meisel Mikolajczyk, F" sort="Meisel Mikolajczyk, F" uniqKey="Meisel Mikolajczyk F" first="F" last="Meisel-Mikolajczyk">F. Meisel-Mikolajczyk</name>
<name sortKey="Stelmach, E" sort="Stelmach, E" uniqKey="Stelmach E" first="E" last="Stelmach">E. Stelmach</name>
<name sortKey="Swoboda, E" sort="Swoboda, E" uniqKey="Swoboda E" first="E" last="Swoboda">E. Swoboda</name>
<name sortKey="Zaleska, M" sort="Zaleska, M" uniqKey="Zaleska M" first="M" last="Zaleska">M. Zaleska</name>
</country>
<country name="Inde"><noRegion><name sortKey="Jamal, S" sort="Jamal, S" uniqKey="Jamal S" first="S" last="Jamal">S. Jamal</name>
</noRegion>
<name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name>
<name sortKey="Manokaran, G" sort="Manokaran, G" uniqKey="Manokaran G" first="G" last="Manokaran">G. Manokaran</name>
<name sortKey="Pani, S" sort="Pani, S" uniqKey="Pani S" first="S" last="Pani">S. Pani</name>
<name sortKey="Tripathi, F M" sort="Tripathi, F M" uniqKey="Tripathi F" first="F. M" last="Tripathi">F. M Tripathi</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00AF20 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00AF20 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:C535ADCA81C224AFC0F09C9E518132C914E3740A |texte= Bacteriological studies of blood, tissue fluid, lymph and lymph nodes in patients with acute dermatolymphangioadenitis (DLA) in course of ‘filarial’ lymphedema }}
![]() | This area was generated with Dilib version V0.6.31. | ![]() |