Comparison of a 1-day and a 2-day protocol for lymphatic mapping and sentinel lymph node biopsy in patients with nonpalpable breast cancer
Identifieur interne : 006349 ( Main/Exploration ); précédent : 006348; suivant : 006350Comparison of a 1-day and a 2-day protocol for lymphatic mapping and sentinel lymph node biopsy in patients with nonpalpable breast cancer
Auteurs : S. Van Esser [Pays-Bas] ; M. Hobbelink [Pays-Bas] ; J. W. Van Isselt [Pays-Bas] ; W. P. Th. M. Mali [Pays-Bas] ; I. H. M. Borel Rinkes [Pays-Bas] ; R. Van Hillegersberg [Pays-Bas]Source :
- European Journal of Nuclear Medicine and Molecular Imaging [ 1619-7070 ] ; 2009.
Abstract
To compare the identification rate of the sentinel node in a 1-day protocol versus a 2-day protocol in patients with a nonpalpable breast carcinoma.
In the 1-day protocol an average dose of 120 MBq 99mTc-nanocolloid was injected intratumorally on the day of surgery, and in the 2-day protocol an average dose of 370 MBq 99mTc-nanocolloid was injected intratumorally the day before surgery. Both a gamma ray detection probe and patent blue were used to locate the sentinel node.
In 57 of 67 patients (85%) treated in the 1-day protocol and in 51 of 56 patients (91%) treated in the 2-day protocol the sentinel node was detected (
There was no significant difference in the identification rate of the sentinel node between the 1-day protocol and the 2-day protocol in patients diagnosed with a nonpalpable breast carcinoma.
Url:
DOI: 10.1007/s00259-009-1114-0
PubMed: 19319528
PubMed Central: 2724640
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><sec><title>Purpose</title>
<p>To compare the identification rate of the sentinel node in a 1-day protocol versus a 2-day protocol in patients with a nonpalpable breast carcinoma.</p>
</sec>
<sec><title>Methods</title>
<p>In the 1-day protocol an average dose of 120 MBq <sup>99m</sup>
Tc-nanocolloid was injected intratumorally on the day of surgery, and in the 2-day protocol an average dose of 370 MBq <sup>99m</sup>
Tc-nanocolloid was injected intratumorally the day before surgery. Both a gamma ray detection probe and patent blue were used to locate the sentinel node.</p>
</sec>
<sec><title>Results</title>
<p>In 57 of 67 patients (85%) treated in the 1-day protocol and in 51 of 56 patients (91%) treated in the 2-day protocol the sentinel node was detected (<italic>p</italic>
=0.311). Of the patients in the 1-day protocol and the 2-day protocol, respectively, 18 (27%) and 13 (23%) showed metastasis (<italic>p</italic>
=0.975)</p>
</sec>
<sec><title>Conclusion</title>
<p>There was no significant difference in the identification rate of the sentinel node between the 1-day protocol and the 2-day protocol in patients diagnosed with a nonpalpable breast carcinoma.</p>
</sec>
</div>
</front>
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