Cutaneous angiosarcoma complicating morbid obesity
Identifieur interne : 00A136 ( Main/Exploration ); précédent : 00A135; suivant : 00A137Cutaneous angiosarcoma complicating morbid obesity
Auteurs : Muhammad Azam [États-Unis] ; M. Hossein Saboorian [États-Unis] ; Samuel Bieligk [États-Unis] ; Todd Smith [États-Unis] ; Kyle Molberg [États-Unis]Source :
- Archives of pathology & laboratory medicine : (1976) [ 0363-0153 ] ; 2001.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Adulte.
English descriptors
- KwdEn :
Abstract
. Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a multicentric, high-grade angiosarcoma with bilateral superficial inguinal lymph node metastases. Histologically, conventional vasoformative areas were admixed with poorly differentiated sheets of spindle and epithelioid cells. Factor VIII was focally positive (membranous), whereas CD31 showed robust, diffuse positivity (membranous and cytoplasmic). The initial margins of resection were negative, and no follow-up radiation or chemotherapy was given. Following a recurrence at the previous excision site, the patient died 7 months after the surgery. Postmortem examination revealed a widely metastatic tumor that involved multiple organ systems. We believe this is the second report of cutaneous angiosarcoma occurring in a chronically lymphedematous abdominal panniculus due to morbid obesity.
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000852
- to stream PascalFrancis, to step Curation: 000108
- to stream PascalFrancis, to step Checkpoint: 000850
- to stream Main, to step Merge: 00A608
- to stream Main, to step Curation: 00A136
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Cutaneous angiosarcoma complicating morbid obesity</title><author><name sortKey="Azam, Muhammad" sort="Azam, Muhammad" uniqKey="Azam M" first="Muhammad" last="Azam">Muhammad Azam</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Pathology, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Saboorian, M Hossein" sort="Saboorian, M Hossein" uniqKey="Saboorian M" first="M. Hossein" last="Saboorian">M. Hossein Saboorian</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Pathology, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Bieligk, Samuel" sort="Bieligk, Samuel" uniqKey="Bieligk S" first="Samuel" last="Bieligk">Samuel Bieligk</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Surgery, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Todd" sort="Smith, Todd" uniqKey="Smith T" first="Todd" last="Smith">Todd Smith</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Surgery, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Molberg, Kyle" sort="Molberg, Kyle" uniqKey="Molberg K" first="Kyle" last="Molberg">Kyle Molberg</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Pathology, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">01-0246996</idno><date when="2001">2001</date><idno type="stanalyst">PASCAL 01-0246996 INIST</idno><idno type="RBID">Pascal:01-0246996</idno><idno type="wicri:Area/PascalFrancis/Corpus">000852</idno><idno type="wicri:Area/PascalFrancis/Curation">000108</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000850</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000850</idno><idno type="wicri:doubleKey">0363-0153:2001:Azam M:cutaneous:angiosarcoma:complicating</idno><idno type="wicri:Area/Main/Merge">00A608</idno><idno type="wicri:Area/Main/Curation">00A136</idno><idno type="wicri:Area/Main/Exploration">00A136</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Cutaneous angiosarcoma complicating morbid obesity</title><author><name sortKey="Azam, Muhammad" sort="Azam, Muhammad" uniqKey="Azam M" first="Muhammad" last="Azam">Muhammad Azam</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Pathology, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Saboorian, M Hossein" sort="Saboorian, M Hossein" uniqKey="Saboorian M" first="M. Hossein" last="Saboorian">M. Hossein Saboorian</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Pathology, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Bieligk, Samuel" sort="Bieligk, Samuel" uniqKey="Bieligk S" first="Samuel" last="Bieligk">Samuel Bieligk</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Surgery, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Todd" sort="Smith, Todd" uniqKey="Smith T" first="Todd" last="Smith">Todd Smith</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Surgery, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author><author><name sortKey="Molberg, Kyle" sort="Molberg, Kyle" uniqKey="Molberg K" first="Kyle" last="Molberg">Kyle Molberg</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Pathology, The University of Texas Southwestern Medical Center</s1><s2>Dallas, Tex.</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Dallas, Tex.</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Archives of pathology & laboratory medicine : (1976)</title><title level="j" type="abbreviated">Arch. pathol. lab. med. : (1976)</title><idno type="ISSN">0363-0153</idno><imprint><date when="2001">2001</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Archives of pathology & laboratory medicine : (1976)</title><title level="j" type="abbreviated">Arch. pathol. lab. med. : (1976)</title><idno type="ISSN">0363-0153</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Angiosarcoma</term><term>Case study</term><term>Clinical investigation</term><term>Female</term><term>Immunohistochemistry</term><term>Lymphedema</term><term>Nutritional status</term><term>Obesity</term><term>Sarcoma</term><term>Severe</term><term>Skin</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Angiosarcome</term><term>Peau</term><term>Obésité</term><term>Grave</term><term>Lymphoedème</term><term>Immunohistochimie</term><term>Exploration clinique</term><term>Etude cas</term><term>Adulte</term><term>Femelle</term><term>Sarcome</term><term>Etat nutritionnel</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Adulte</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">. Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a multicentric, high-grade angiosarcoma with bilateral superficial inguinal lymph node metastases. Histologically, conventional vasoformative areas were admixed with poorly differentiated sheets of spindle and epithelioid cells. Factor VIII was focally positive (membranous), whereas CD31 showed robust, diffuse positivity (membranous and cytoplasmic). The initial margins of resection were negative, and no follow-up radiation or chemotherapy was given. Following a recurrence at the previous excision site, the patient died 7 months after the surgery. Postmortem examination revealed a widely metastatic tumor that involved multiple organ systems. We believe this is the second report of cutaneous angiosarcoma occurring in a chronically lymphedematous abdominal panniculus due to morbid obesity.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Azam, Muhammad" sort="Azam, Muhammad" uniqKey="Azam M" first="Muhammad" last="Azam">Muhammad Azam</name></noRegion><name sortKey="Bieligk, Samuel" sort="Bieligk, Samuel" uniqKey="Bieligk S" first="Samuel" last="Bieligk">Samuel Bieligk</name><name sortKey="Molberg, Kyle" sort="Molberg, Kyle" uniqKey="Molberg K" first="Kyle" last="Molberg">Kyle Molberg</name><name sortKey="Saboorian, M Hossein" sort="Saboorian, M Hossein" uniqKey="Saboorian M" first="M. Hossein" last="Saboorian">M. Hossein Saboorian</name><name sortKey="Smith, Todd" sort="Smith, Todd" uniqKey="Smith T" first="Todd" last="Smith">Todd Smith</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00A136 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00A136 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:01-0246996
|texte= Cutaneous angiosarcoma complicating morbid obesity
}}
| This area was generated with Dilib version V0.6.31. |  |