LymphedemaV1, PascalFrancis, Curation, bibRecord, 000108

Cutaneous angiosarcoma complicating morbid obesity

Identifieur interne : 000108 ( PascalFrancis/Curation ); précédent : 000107; suivant : 000109

Cutaneous angiosarcoma complicating morbid obesity

Auteurs : Muhammad Azam [États-Unis] ; M. Hossein Saboorian [États-Unis] ; Samuel Bieligk [États-Unis] ; Todd Smith [États-Unis] ; Kyle Molberg [États-Unis]

Source :

Archives of pathology & laboratory medicine : (1976) [ 0363-0153 ] ; 2001.

RBID : Pascal:01-0246996

Descripteurs français

Pascal (Inist)
- Angiosarcome, Peau, Obésité, Grave, Lymphoedème, Immunohistochimie, Exploration clinique, Etude cas, Adulte, Femelle, Sarcome, Etat nutritionnel.
Wicri :
- topic : Adulte.

English descriptors

KwdEn :
- Adult, Angiosarcoma, Case study, Clinical investigation, Female, Immunohistochemistry, Lymphedema, Nutritional status, Obesity, Sarcoma, Severe, Skin.

Abstract

. Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a multicentric, high-grade angiosarcoma with bilateral superficial inguinal lymph node metastases. Histologically, conventional vasoformative areas were admixed with poorly differentiated sheets of spindle and epithelioid cells. Factor VIII was focally positive (membranous), whereas CD31 showed robust, diffuse positivity (membranous and cytoplasmic). The initial margins of resection were negative, and no follow-up radiation or chemotherapy was given. Following a recurrence at the previous excision site, the patient died 7 months after the surgery. Postmortem examination revealed a widely metastatic tumor that involved multiple organ systems. We believe this is the second report of cutaneous angiosarcoma occurring in a chronically lymphedematous abdominal panniculus due to morbid obesity.

A01	`01`	`1`		`@0 0363-0153`
A02	`01`			`@0 APLMAS`
A03		`1`		`@0 Arch. pathol. lab. med. : (1976)`
A05				`@2 125`
A06				`@2 4`
A08	`01`	`1`	`ENG`	`@1 Cutaneous angiosarcoma complicating morbid obesity`
A11	`01`	`1`		`@1 AZAM (Muhammad)`
A11	`02`	`1`		`@1 SABOORIAN (M. Hossein)`
A11	`03`	`1`		`@1 BIELIGK (Samuel)`
A11	`04`	`1`		`@1 SMITH (Todd)`
A11	`05`	`1`		`@1 MOLBERG (Kyle)`
A14	`01`			`@1 Department of Pathology, The University of Texas Southwestern Medical Center @2 Dallas, Tex. @3 USA @Z 1 aut. @Z 2 aut. @Z 5 aut.`
A14	`02`			`@1 Department of Surgery, The University of Texas Southwestern Medical Center @2 Dallas, Tex. @3 USA @Z 3 aut. @Z 4 aut.`
A20				`@1 531-533`
A21				`@1 2001`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 2050 @5 354000098118530130`
A44				`@0 0000 @1 © 2001 INIST-CNRS. All rights reserved.`
A45				`@0 21 ref.`
A47	`01`	`1`		`@0 01-0246996`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Archives of pathology & laboratory medicine : (1976)`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 . Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a multicentric, high-grade angiosarcoma with bilateral superficial inguinal lymph node metastases. Histologically, conventional vasoformative areas were admixed with poorly differentiated sheets of spindle and epithelioid cells. Factor VIII was focally positive (membranous), whereas CD31 showed robust, diffuse positivity (membranous and cytoplasmic). The initial margins of resection were negative, and no follow-up radiation or chemotherapy was given. Following a recurrence at the previous excision site, the patient died 7 months after the surgery. Postmortem examination revealed a widely metastatic tumor that involved multiple organ systems. We believe this is the second report of cutaneous angiosarcoma occurring in a chronically lymphedematous abdominal panniculus due to morbid obesity.
C02	`01`	`X`		`@0 002B08A`
C03	`01`	`X`	`FRE`	`@0 Angiosarcome @5 01`
C03	`01`	`X`	`ENG`	`@0 Angiosarcoma @5 01`
C03	`01`	`X`	`SPA`	`@0 Angiosarcoma @5 01`
C03	`02`	`X`	`FRE`	`@0 Peau @5 02`
C03	`02`	`X`	`ENG`	`@0 Skin @5 02`
C03	`02`	`X`	`SPA`	`@0 Piel @5 02`
C03	`03`	`X`	`FRE`	`@0 Obésité @5 04`
C03	`03`	`X`	`ENG`	`@0 Obesity @5 04`
C03	`03`	`X`	`SPA`	`@0 Obesidad @5 04`
C03	`04`	`X`	`FRE`	`@0 Grave @5 05`
C03	`04`	`X`	`ENG`	`@0 Severe @5 05`
C03	`04`	`X`	`SPA`	`@0 Grave @5 05`
C03	`05`	`X`	`FRE`	`@0 Lymphoedème @5 07`
C03	`05`	`X`	`ENG`	`@0 Lymphedema @5 07`
C03	`05`	`X`	`SPA`	`@0 Linfedema @5 07`
C03	`06`	`X`	`FRE`	`@0 Immunohistochimie @5 10`
C03	`06`	`X`	`ENG`	`@0 Immunohistochemistry @5 10`
C03	`06`	`X`	`SPA`	`@0 Inmunohistoquímica @5 10`
C03	`07`	`X`	`FRE`	`@0 Exploration clinique @5 11`
C03	`07`	`X`	`ENG`	`@0 Clinical investigation @5 11`
C03	`07`	`X`	`SPA`	`@0 Exploración clínica @5 11`
C03	`08`	`X`	`FRE`	`@0 Etude cas @5 17`
C03	`08`	`X`	`ENG`	`@0 Case study @5 17`
C03	`08`	`X`	`SPA`	`@0 Estudio caso @5 17`
C03	`09`	`X`	`FRE`	`@0 Adulte @5 20`
C03	`09`	`X`	`ENG`	`@0 Adult @5 20`
C03	`09`	`X`	`SPA`	`@0 Adulto @5 20`
C03	`10`	`X`	`FRE`	`@0 Femelle @5 21`
C03	`10`	`X`	`ENG`	`@0 Female @5 21`
C03	`10`	`X`	`SPA`	`@0 Hembra @5 21`
C03	`11`	`X`	`FRE`	`@0 Sarcome @5 25`
C03	`11`	`X`	`ENG`	`@0 Sarcoma @5 25`
C03	`11`	`X`	`SPA`	`@0 Sarcoma @5 25`
C03	`12`	`X`	`FRE`	`@0 Etat nutritionnel @5 27`
C03	`12`	`X`	`ENG`	`@0 Nutritional status @5 27`
C03	`12`	`X`	`SPA`	`@0 Estado nutricional @5 27`
C07	`01`	`X`	`FRE`	`@0 Homme`
C07	`01`	`X`	`ENG`	`@0 Human`
C07	`01`	`X`	`SPA`	`@0 Hombre`
C07	`02`	`X`	`FRE`	`@0 Appareil circulatoire pathologie @5 37`
C07	`02`	`X`	`ENG`	`@0 Cardiovascular disease @5 37`
C07	`02`	`X`	`SPA`	`@0 Aparato circulatorio patología @5 37`
C07	`03`	`X`	`FRE`	`@0 Vaisseau sanguin pathologie @5 38`
C07	`03`	`X`	`ENG`	`@0 Vascular disease @5 38`
C07	`03`	`X`	`SPA`	`@0 Vaso sanguíneo patología @5 38`
C07	`04`	`X`	`FRE`	`@0 Tumeur maligne @5 39`
C07	`04`	`X`	`ENG`	`@0 Malignant tumor @5 39`
C07	`04`	`X`	`SPA`	`@0 Tumor maligno @5 39`
C07	`05`	`X`	`FRE`	`@0 Peau pathologie @5 40`
C07	`05`	`X`	`ENG`	`@0 Skin disease @5 40`
C07	`05`	`X`	`SPA`	`@0 Piel patología @5 40`
C07	`06`	`X`	`FRE`	`@0 Trouble nutrition @5 45`
C07	`06`	`X`	`ENG`	`@0 Nutrition disorder @5 45`
C07	`06`	`X`	`SPA`	`@0 Trastorno nutricíon @5 45`
C07	`07`	`X`	`FRE`	`@0 Lymphatique pathologie @5 54`
C07	`07`	`X`	`ENG`	`@0 Lymphatic vessel disease @5 54`
C07	`07`	`X`	`SPA`	`@0 Linfático patología @5 54`
C07	`08`	`X`	`FRE`	`@0 Anatomopathologie @5 61`
C07	`08`	`X`	`ENG`	`@0 Pathology @5 61`
C07	`08`	`X`	`SPA`	`@0 Anatomía patológica @5 61`
N21				`@1 169`

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Pascal:01-0246996

Le document en format XML

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<author><name sortKey="Molberg, Kyle" sort="Molberg, Kyle" uniqKey="Molberg K" first="Kyle" last="Molberg">Kyle Molberg</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Cutaneous angiosarcoma complicating morbid obesity</title>
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<s2>Dallas, Tex.</s2>
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<author><name sortKey="Saboorian, M Hossein" sort="Saboorian, M Hossein" uniqKey="Saboorian M" first="M. Hossein" last="Saboorian">M. Hossein Saboorian</name>
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<author><name sortKey="Bieligk, Samuel" sort="Bieligk, Samuel" uniqKey="Bieligk S" first="Samuel" last="Bieligk">Samuel Bieligk</name>
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<author><name sortKey="Smith, Todd" sort="Smith, Todd" uniqKey="Smith T" first="Todd" last="Smith">Todd Smith</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Surgery, The University of Texas Southwestern Medical Center</s1>
<s2>Dallas, Tex.</s2>
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<author><name sortKey="Molberg, Kyle" sort="Molberg, Kyle" uniqKey="Molberg K" first="Kyle" last="Molberg">Kyle Molberg</name>
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<series><title level="j" type="main">Archives of pathology & laboratory medicine : (1976)</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Angiosarcoma</term>
<term>Case study</term>
<term>Clinical investigation</term>
<term>Female</term>
<term>Immunohistochemistry</term>
<term>Lymphedema</term>
<term>Nutritional status</term>
<term>Obesity</term>
<term>Sarcoma</term>
<term>Severe</term>
<term>Skin</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Angiosarcome</term>
<term>Peau</term>
<term>Obésité</term>
<term>Grave</term>
<term>Lymphoedème</term>
<term>Immunohistochimie</term>
<term>Exploration clinique</term>
<term>Etude cas</term>
<term>Adulte</term>
<term>Femelle</term>
<term>Sarcome</term>
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<front><div type="abstract" xml:lang="en">. Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a multicentric, high-grade angiosarcoma with bilateral superficial inguinal lymph node metastases. Histologically, conventional vasoformative areas were admixed with poorly differentiated sheets of spindle and epithelioid cells. Factor VIII was focally positive (membranous), whereas CD31 showed robust, diffuse positivity (membranous and cytoplasmic). The initial margins of resection were negative, and no follow-up radiation or chemotherapy was given. Following a recurrence at the previous excision site, the patient died 7 months after the surgery. Postmortem examination revealed a widely metastatic tumor that involved multiple organ systems. We believe this is the second report of cutaneous angiosarcoma occurring in a chronically lymphedematous abdominal panniculus due to morbid obesity.</div>
</front>
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<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
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<fA14 i1="02"><s1>Department of Surgery, The University of Texas Southwestern Medical Center</s1>
<s2>Dallas, Tex.</s2>
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<fC01 i1="01" l="ENG"><s0>. Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a multicentric, high-grade angiosarcoma with bilateral superficial inguinal lymph node metastases. Histologically, conventional vasoformative areas were admixed with poorly differentiated sheets of spindle and epithelioid cells. Factor VIII was focally positive (membranous), whereas CD31 showed robust, diffuse positivity (membranous and cytoplasmic). The initial margins of resection were negative, and no follow-up radiation or chemotherapy was given. Following a recurrence at the previous excision site, the patient died 7 months after the surgery. Postmortem examination revealed a widely metastatic tumor that involved multiple organ systems. We believe this is the second report of cutaneous angiosarcoma occurring in a chronically lymphedematous abdominal panniculus due to morbid obesity.</s0>
</fC01>
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<s5>04</s5>
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<fC03 i1="04" i2="X" l="FRE"><s0>Grave</s0>
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<s5>05</s5>
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<fC03 i1="04" i2="X" l="SPA"><s0>Grave</s0>
<s5>05</s5>
</fC03>
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<s5>07</s5>
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<s5>07</s5>
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<fC03 i1="07" i2="X" l="FRE"><s0>Exploration clinique</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Clinical investigation</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Exploración clínica</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Etude cas</s0>
<s5>17</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Case study</s0>
<s5>17</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Estudio caso</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Adulte</s0>
<s5>20</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Adult</s0>
<s5>20</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Adulto</s0>
<s5>20</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Femelle</s0>
<s5>21</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Female</s0>
<s5>21</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Hembra</s0>
<s5>21</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Sarcome</s0>
<s5>25</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Sarcoma</s0>
<s5>25</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Sarcoma</s0>
<s5>25</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Etat nutritionnel</s0>
<s5>27</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Nutritional status</s0>
<s5>27</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Estado nutricional</s0>
<s5>27</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Appareil circulatoire pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Cardiovascular disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Aparato circulatorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Vaisseau sanguin pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Vascular disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Vaso sanguíneo patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Tumeur maligne</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Malignant tumor</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Tumor maligno</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Peau pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Skin disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Piel patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Trouble nutrition</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Nutrition disorder</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Trastorno nutricíon</s0>
<s5>45</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Lymphatique pathologie</s0>
<s5>54</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Lymphatic vessel disease</s0>
<s5>54</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Linfático patología</s0>
<s5>54</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Anatomopathologie</s0>
<s5>61</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Pathology</s0>
<s5>61</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Anatomía patológica</s0>
<s5>61</s5>
</fC07>
<fN21><s1>169</s1>
</fN21>
</pA>
</standard>
</inist>
</record>

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   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
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   |clé=     Pascal:01-0246996
   |texte=   Cutaneous angiosarcoma complicating morbid obesity
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Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

	Serveur d'exploration sur le lymphœdème
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Serveur d'exploration sur le lymphœdème

Cutaneous angiosarcoma complicating morbid obesity

Cutaneous angiosarcoma complicating morbid obesity

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Descripteurs français

English descriptors

Abstract

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