LymphedemaV1, Main, Exploration, bibRecord, 001980

Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic

Identifieur interne : 001980 ( Main/Exploration ); précédent : 001979; suivant : 001981

Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic

Auteurs : Gregory S. Noland ; Stephen Blount ; Manuel Gonzalez

Source :

The American Journal of Tropical Medicine and Hygiene [ 0002-9637 ] ; 2015.

RBID : PMC:4674248

Descripteurs français

KwdFr :
- Albendazole (usage thérapeutique), Diéthylcarbamazine (usage thérapeutique), Enfant, Enfant d'âge préscolaire, Enquêtes de santé, Femelle, Filaricides (usage thérapeutique), Filariose lymphatique (), Filariose lymphatique (traitement médicamenteux), Filariose lymphatique (épidémiologie), Humains, Immunochromatographie, Mâle, République dominicaine (épidémiologie), Éradication de maladie ().
MESH :
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Albendazole, Diéthylcarbamazine, Filaricides.
- épidémiologie : Filariose lymphatique, République dominicaine.
- Enfant, Enfant d'âge préscolaire, Enquêtes de santé, Femelle, Filariose lymphatique, Humains, Immunochromatographie, Mâle, Éradication de maladie.
Wicri :
- geographic : République dominicaine.

English descriptors

KwdEn :
- Albendazole (therapeutic use), Child, Child, Preschool, Diethylcarbamazine (therapeutic use), Disease Eradication (methods), Dominican Republic (epidemiology), Elephantiasis, Filarial (drug therapy), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (prevention & control), Female, Filaricides (therapeutic use), Health Surveys, Humans, Immunochromatography, Male.
MESH :
- chemical , therapeutic use : Albendazole, Diethylcarbamazine, Filaricides.
- geographic , epidemiology : Dominican Republic.
- drug therapy : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial.
- methods : Disease Eradication.
- prevention & control : Elephantiasis, Filarial.
- Child, Child, Preschool, Female, Health Surveys, Humans, Immunochromatography, Male.

Abstract

The Dominican Republic is one of four remaining countries in the Americas with lymphatic filariasis (LF). Annual mass drug administration (MDA) with albendazole and diethylcarbamazine was conducted in La Ciénaga, an impoverished urban barrio in Santo Domingo, from 2004 to 2006. Eight years after the last MDA, a transmission assessment survey (TAS) was conducted in November–December 2014 to determine if LF transmission remains absent. Of 815 first and second grade primary school students (mean age: 6.51 years; range 5–9) tested by immunochromatographic test (ICT), zero (0.0%) were positive. This is below the TAS critical cutoff of nine, indicating that the area “passed” TAS and that transmission remains interrupted in La Ciénaga. Importantly, this also provides evidence that three rounds of effective (> 65% coverage) MDA, likely aided by environmental improvements and periodic school-based albendazole monotherapy MDA, achieved interruption of LF transmission from a relatively low-transmission setting.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674248

DOI: 10.4269/ajtmh.15-0204
PubMed: 26503279
PubMed Central: 4674248

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>The Dominican Republic is one of four remaining countries in the Americas with lymphatic filariasis (LF). Annual mass drug administration (MDA) with albendazole and diethylcarbamazine was conducted in La Ciénaga, an impoverished urban <italic>barrio</italic>
 in Santo Domingo, from 2004 to 2006. Eight years after the last MDA, a transmission assessment survey (TAS) was conducted in November–December 2014 to determine if LF transmission remains absent. Of 815 first and second grade primary school students (mean age: 6.51 years; range 5–9) tested by immunochromatographic test (ICT), zero (0.0%) were positive. This is below the TAS critical cutoff of nine, indicating that the area “passed” TAS and that transmission remains interrupted in La Ciénaga. Importantly, this also provides evidence that three rounds of effective (> 65% coverage) MDA, likely aided by environmental improvements and periodic school-based albendazole monotherapy MDA, achieved interruption of LF transmission from a relatively low-transmission setting.</p>
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Serveur d'exploration sur le lymphœdème

Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic

Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.