Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic
Identifieur interne : 000250 ( Pmc/Corpus ); précédent : 000249; suivant : 000251Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic
Auteurs : Gregory S. Noland ; Stephen Blount ; Manuel GonzalezSource :
- The American Journal of Tropical Medicine and Hygiene [ 0002-9637 ] ; 2015.
Abstract
The Dominican Republic is one of four remaining countries in the Americas with lymphatic filariasis (LF). Annual mass drug administration (MDA) with albendazole and diethylcarbamazine was conducted in La Ciénaga, an impoverished urban
Url:
DOI: 10.4269/ajtmh.15-0204
PubMed: 26503279
PubMed Central: 4674248
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic</title><author><name sortKey="Noland, Gregory S" sort="Noland, Gregory S" uniqKey="Noland G" first="Gregory S." last="Noland">Gregory S. Noland</name></author><author><name sortKey="Blount, Stephen" sort="Blount, Stephen" uniqKey="Blount S" first="Stephen" last="Blount">Stephen Blount</name></author><author><name sortKey="Gonzalez, Manuel" sort="Gonzalez, Manuel" uniqKey="Gonzalez M" first="Manuel" last="Gonzalez">Manuel Gonzalez</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26503279</idno><idno type="pmc">4674248</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674248</idno><idno type="RBID">PMC:4674248</idno><idno type="doi">10.4269/ajtmh.15-0204</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000250</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000250</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic</title><author><name sortKey="Noland, Gregory S" sort="Noland, Gregory S" uniqKey="Noland G" first="Gregory S." last="Noland">Gregory S. Noland</name></author><author><name sortKey="Blount, Stephen" sort="Blount, Stephen" uniqKey="Blount S" first="Stephen" last="Blount">Stephen Blount</name></author><author><name sortKey="Gonzalez, Manuel" sort="Gonzalez, Manuel" uniqKey="Gonzalez M" first="Manuel" last="Gonzalez">Manuel Gonzalez</name></author></analytic><series><title level="j">The American Journal of Tropical Medicine and Hygiene</title><idno type="ISSN">0002-9637</idno><idno type="eISSN">1476-1645</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The Dominican Republic is one of four remaining countries in the Americas with lymphatic filariasis (LF). Annual mass drug administration (MDA) with albendazole and diethylcarbamazine was conducted in La Ciénaga, an impoverished urban <italic>barrio</italic> in Santo Domingo, from 2004 to 2006. Eight years after the last MDA, a transmission assessment survey (TAS) was conducted in November–December 2014 to determine if LF transmission remains absent. Of 815 first and second grade primary school students (mean age: 6.51 years; range 5–9) tested by immunochromatographic test (ICT), zero (0.0%) were positive. This is below the TAS critical cutoff of nine, indicating that the area “passed” TAS and that transmission remains interrupted in La Ciénaga. Importantly, this also provides evidence that three rounds of effective (> 65% coverage) MDA, likely aided by environmental improvements and periodic school-based albendazole monotherapy MDA, achieved interruption of LF transmission from a relatively low-transmission setting.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Am J Trop Med Hyg</journal-id><journal-id journal-id-type="iso-abbrev">Am. J. Trop. Med. Hyg</journal-id><journal-id journal-id-type="publisher-id">tpmd</journal-id><journal-title-group><journal-title>The American Journal of Tropical Medicine and Hygiene</journal-title></journal-title-group><issn pub-type="ppub">0002-9637</issn><issn pub-type="epub">1476-1645</issn><publisher><publisher-name>The American Society of Tropical Medicine and Hygiene</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26503279</article-id><article-id pub-id-type="pmc">4674248</article-id><article-id pub-id-type="doi">10.4269/ajtmh.15-0204</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Post-Mass Drug Administration Transmission Assessment Survey for Elimination of Lymphatic Filariasis in La Ciénaga, Dominican Republic</article-title><alt-title alt-title-type="left-running-head">NOLAND AND OTHERS</alt-title><alt-title alt-title-type="right-running-head">POST-MDA LF TAS IN THE DOMINICAN REPUBLIC</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Noland</surname><given-names>Gregory S.</given-names></name><xref ref-type="corresp" rid="COR1">*</xref></contrib><contrib contrib-type="author"><name><surname>Blount</surname><given-names>Stephen</given-names></name></contrib><contrib contrib-type="author"><name><surname>Gonzalez</surname><given-names>Manuel</given-names></name></contrib></contrib-group><aff id="AFF1">The Carter Center, Atlanta, Georgia; Centro de Control de Enfermedades Tropicales, Santo Domingo, Dominican Republic</aff><author-notes><corresp id="COR1">*Address corresponding to Gregory S. Noland, The Carter Center, 453 Freedom Parkway, Atlanta, GA 30307. E-mail: <email>gregory.noland@cartercenter.org</email></corresp></author-notes><pub-date pub-type="ppub"><day>09</day><month>12</month><year>2015</year></pub-date><volume>93</volume><issue>6</issue><fpage>1292</fpage><lpage>1294</lpage><history><date date-type="received"><day>15</day><month>3</month><year>2015</year></date><date date-type="accepted"><day>22</day><month>7</month><year>2015</year></date></history><permissions><copyright-statement>©The American Society of Tropical Medicine and Hygiene</copyright-statement><copyright-year>2015</copyright-year></permissions><abstract><p>The Dominican Republic is one of four remaining countries in the Americas with lymphatic filariasis (LF). Annual mass drug administration (MDA) with albendazole and diethylcarbamazine was conducted in La Ciénaga, an impoverished urban <italic>barrio</italic> in Santo Domingo, from 2004 to 2006. Eight years after the last MDA, a transmission assessment survey (TAS) was conducted in November–December 2014 to determine if LF transmission remains absent. Of 815 first and second grade primary school students (mean age: 6.51 years; range 5–9) tested by immunochromatographic test (ICT), zero (0.0%) were positive. This is below the TAS critical cutoff of nine, indicating that the area “passed” TAS and that transmission remains interrupted in La Ciénaga. Importantly, this also provides evidence that three rounds of effective (> 65% coverage) MDA, likely aided by environmental improvements and periodic school-based albendazole monotherapy MDA, achieved interruption of LF transmission from a relatively low-transmission setting.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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