Integrity of Narrow Epithelial Tubes in the C. elegans Excretory System Requires a Transient Luminal Matrix
Identifieur interne : 000F50 ( Main/Exploration ); précédent : 000F49; suivant : 000F51Integrity of Narrow Epithelial Tubes in the C. elegans Excretory System Requires a Transient Luminal Matrix
Auteurs : Hasreet K. Gill [États-Unis] ; Jennifer D. Cohen [États-Unis] ; Jesus Ayala-Figueroa [États-Unis] ; Rachel Forman-Rubinsky [États-Unis] ; Corey Poggioli [États-Unis] ; Kevin Bickard [États-Unis] ; Jean M. Parry [États-Unis] ; Pu Pu [États-Unis] ; David H. Hall [États-Unis] ; Meera V. Sundaram [États-Unis]Source :
- PLoS Genetics [ 1553-7390 ] ; 2016.
Abstract
Most epithelial cells secrete a glycoprotein-rich apical extracellular matrix that can have diverse but still poorly understood roles in development and physiology. Zona Pellucida (ZP) domain glycoproteins are common constituents of these matrices, and their loss in humans is associated with a number of diseases. Understanding of the functions, organization and regulation of apical matrices has been hampered by difficulties in imaging them both
Url:
DOI: 10.1371/journal.pgen.1006205
PubMed: 27482894
PubMed Central: 4970718
Affiliations:
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Excretory System Requires a Transient Luminal Matrix</title>
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Excretory System Requires a Transient Luminal Matrix</title>
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<front><div type="abstract" xml:lang="en"><p>Most epithelial cells secrete a glycoprotein-rich apical extracellular matrix that can have diverse but still poorly understood roles in development and physiology. Zona Pellucida (ZP) domain glycoproteins are common constituents of these matrices, and their loss in humans is associated with a number of diseases. Understanding of the functions, organization and regulation of apical matrices has been hampered by difficulties in imaging them both <italic>in vivo</italic>
and <italic>ex vivo</italic>
. We identified the PAN-Apple, mucin and ZP domain glycoprotein LET-653 as an early and transient apical matrix component that shapes developing epithelia in <italic>C</italic>
. <italic>elegans</italic>
. LET-653 has modest effects on shaping of the vulva and epidermis, but is essential to prevent lumen fragmentation in the very narrow, unicellular excretory duct tube. We were able to image the transient LET-653 matrix by both live confocal imaging and transmission electron microscopy. Structure/function and fluorescence recovery after photobleaching studies revealed that LET-653 exists in two separate luminal matrix pools, a loose fibrillar matrix in the central core of the lumen, to which it binds dynamically via its PAN domains, and an apical-membrane-associated matrix, to which it binds stably via its ZP domain. The PAN domains are both necessary and sufficient to confer a cyclic pattern of duct lumen localization that precedes each molt, while the ZP domain is required for lumen integrity. Ectopic expression of full-length LET-653, but not the PAN domains alone, could expand lumen diameter in the developing gut tube, where LET-653 is not normally expressed. Together, these data support a model in which the PAN domains regulate the ability of the LET-653 ZP domain to interact with other factors at the apical membrane, and this ZP domain interaction promotes expansion and maintenance of lumen diameter. These data identify a transient apical matrix component present prior to cuticle secretion in <italic>C</italic>
. <italic>elegans</italic>
, demonstrate critical roles for this matrix component in supporting lumen integrity within narrow bore tubes such as those found in the mammalian microvasculature, and reveal functional importance of the evolutionarily conserved ZP domain in this tube protecting activity.</p>
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</author>
<author><name sortKey="Slaaf, Dw" uniqKey="Slaaf D">DW Slaaf</name>
</author>
<author><name sortKey="Vink, H" uniqKey="Vink H">H Vink</name>
</author>
<author><name sortKey="Van Zandvoort, Ma" uniqKey="Van Zandvoort M">MA van Zandvoort</name>
</author>
<author><name sortKey="Oude Egbrink, Mg" uniqKey="Oude Egbrink M">MG oude Egbrink</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tarbell, Jm" uniqKey="Tarbell J">JM Tarbell</name>
</author>
<author><name sortKey="Simon, Si" uniqKey="Simon S">SI Simon</name>
</author>
<author><name sortKey="Curry, Fr" uniqKey="Curry F">FR Curry</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Plaza, S" uniqKey="Plaza S">S Plaza</name>
</author>
<author><name sortKey="Chanut Delalande, H" uniqKey="Chanut Delalande H">H Chanut-Delalande</name>
</author>
<author><name sortKey="Fernandes, I" uniqKey="Fernandes I">I Fernandes</name>
</author>
<author><name sortKey="Wassarman, Pm" uniqKey="Wassarman P">PM Wassarman</name>
</author>
<author><name sortKey="Payre, F" uniqKey="Payre F">F Payre</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Johansson, Me" uniqKey="Johansson M">ME Johansson</name>
</author>
<author><name sortKey="Sjovall, H" uniqKey="Sjovall H">H Sjovall</name>
</author>
<author><name sortKey="Hansson, Gc" uniqKey="Hansson G">GC Hansson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Luschnig, S" uniqKey="Luschnig S">S Luschnig</name>
</author>
<author><name sortKey="Uv, A" uniqKey="Uv A">A Uv</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Herzog, Bh" uniqKey="Herzog B">BH Herzog</name>
</author>
<author><name sortKey="Fu, J" uniqKey="Fu J">J Fu</name>
</author>
<author><name sortKey="Xia, L" uniqKey="Xia L">L Xia</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tran, Dt" uniqKey="Tran D">DT Tran</name>
</author>
<author><name sortKey="Ten Hagen, Kg" uniqKey="Ten Hagen K">KG Ten Hagen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Henderson Toth, Ce" uniqKey="Henderson Toth C">CE Henderson-Toth</name>
</author>
<author><name sortKey="Jahnsen, Ed" uniqKey="Jahnsen E">ED Jahnsen</name>
</author>
<author><name sortKey="Jamarani, R" uniqKey="Jamarani R">R Jamarani</name>
</author>
<author><name sortKey="Al Roubaie, S" uniqKey="Al Roubaie S">S Al-Roubaie</name>
</author>
<author><name sortKey="Jones, Ea" uniqKey="Jones E">EA Jones</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Meder, D" uniqKey="Meder D">D Meder</name>
</author>
<author><name sortKey="Shevchenko, A" uniqKey="Shevchenko A">A Shevchenko</name>
</author>
<author><name sortKey="Simons, K" uniqKey="Simons K">K Simons</name>
</author>
<author><name sortKey="Fullekrug, J" uniqKey="Fullekrug J">J Fullekrug</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xia, L" uniqKey="Xia L">L Xia</name>
</author>
<author><name sortKey="Ju, T" uniqKey="Ju T">T Ju</name>
</author>
<author><name sortKey="Westmuckett, A" uniqKey="Westmuckett A">A Westmuckett</name>
</author>
<author><name sortKey="An, G" uniqKey="An G">G An</name>
</author>
<author><name sortKey="Ivanciu, L" uniqKey="Ivanciu L">L Ivanciu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Doyonnas, R" uniqKey="Doyonnas R">R Doyonnas</name>
</author>
<author><name sortKey="Kershaw, Db" uniqKey="Kershaw D">DB Kershaw</name>
</author>
<author><name sortKey="Duhme, C" uniqKey="Duhme C">C Duhme</name>
</author>
<author><name sortKey="Merkens, H" uniqKey="Merkens H">H Merkens</name>
</author>
<author><name sortKey="Chelliah, S" uniqKey="Chelliah S">S Chelliah</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schacht, V" uniqKey="Schacht V">V Schacht</name>
</author>
<author><name sortKey="Ramirez, Mi" uniqKey="Ramirez M">MI Ramirez</name>
</author>
<author><name sortKey="Hong, Yk" uniqKey="Hong Y">YK Hong</name>
</author>
<author><name sortKey="Hirakawa, S" uniqKey="Hirakawa S">S Hirakawa</name>
</author>
<author><name sortKey="Feng, D" uniqKey="Feng D">D Feng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Takeda, T" uniqKey="Takeda T">T Takeda</name>
</author>
<author><name sortKey="Go, Wy" uniqKey="Go W">WY Go</name>
</author>
<author><name sortKey="Orlando, Ra" uniqKey="Orlando R">RA Orlando</name>
</author>
<author><name sortKey="Farquhar, Mg" uniqKey="Farquhar M">MG Farquhar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Strilic, B" uniqKey="Strilic B">B Strilic</name>
</author>
<author><name sortKey="Eglinger, J" uniqKey="Eglinger J">J Eglinger</name>
</author>
<author><name sortKey="Krieg, M" uniqKey="Krieg M">M Krieg</name>
</author>
<author><name sortKey="Zeeb, M" uniqKey="Zeeb M">M Zeeb</name>
</author>
<author><name sortKey="Axnick, J" uniqKey="Axnick J">J Axnick</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Martin Villar, E" uniqKey="Martin Villar E">E Martin-Villar</name>
</author>
<author><name sortKey="Megias, D" uniqKey="Megias D">D Megias</name>
</author>
<author><name sortKey="Castel, S" uniqKey="Castel S">S Castel</name>
</author>
<author><name sortKey="Yurrita, Mm" uniqKey="Yurrita M">MM Yurrita</name>
</author>
<author><name sortKey="Vilaro, S" uniqKey="Vilaro S">S Vilaro</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Orlando, Ra" uniqKey="Orlando R">RA Orlando</name>
</author>
<author><name sortKey="Takeda, T" uniqKey="Takeda T">T Takeda</name>
</author>
<author><name sortKey="Zak, B" uniqKey="Zak B">B Zak</name>
</author>
<author><name sortKey="Schmieder, S" uniqKey="Schmieder S">S Schmieder</name>
</author>
<author><name sortKey="Benoit, Vm" uniqKey="Benoit V">VM Benoit</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Herzog, Bh" uniqKey="Herzog B">BH Herzog</name>
</author>
<author><name sortKey="Fu, J" uniqKey="Fu J">J Fu</name>
</author>
<author><name sortKey="Wilson, Sj" uniqKey="Wilson S">SJ Wilson</name>
</author>
<author><name sortKey="Hess, Pr" uniqKey="Hess P">PR Hess</name>
</author>
<author><name sortKey="Sen, A" uniqKey="Sen A">A Sen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lane, Mc" uniqKey="Lane M">MC Lane</name>
</author>
<author><name sortKey="Koehl, Ma" uniqKey="Koehl M">MA Koehl</name>
</author>
<author><name sortKey="Wilt, F" uniqKey="Wilt F">F Wilt</name>
</author>
<author><name sortKey="Keller, R" uniqKey="Keller R">R Keller</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hwang, Hy" uniqKey="Hwang H">HY Hwang</name>
</author>
<author><name sortKey="Olson, Sk" uniqKey="Olson S">SK Olson</name>
</author>
<author><name sortKey="Esko, Jd" uniqKey="Esko J">JD Esko</name>
</author>
<author><name sortKey="Horvitz, Hr" uniqKey="Horvitz H">HR Horvitz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Syed, Za" uniqKey="Syed Z">ZA Syed</name>
</author>
<author><name sortKey="Bouge, Al" uniqKey="Bouge A">AL Bouge</name>
</author>
<author><name sortKey="Byri, S" uniqKey="Byri S">S Byri</name>
</author>
<author><name sortKey="Chavoshi, Tm" uniqKey="Chavoshi T">TM Chavoshi</name>
</author>
<author><name sortKey="Tang, E" uniqKey="Tang E">E Tang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Husain, N" uniqKey="Husain N">N Husain</name>
</author>
<author><name sortKey="Pellikka, M" uniqKey="Pellikka M">M Pellikka</name>
</author>
<author><name sortKey="Hong, H" uniqKey="Hong H">H Hong</name>
</author>
<author><name sortKey="Klimentova, T" uniqKey="Klimentova T">T Klimentova</name>
</author>
<author><name sortKey="Choe, Km" uniqKey="Choe K">KM Choe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tonning, A" uniqKey="Tonning A">A Tonning</name>
</author>
<author><name sortKey="Hemphala, J" uniqKey="Hemphala J">J Hemphala</name>
</author>
<author><name sortKey="Tang, E" uniqKey="Tang E">E Tang</name>
</author>
<author><name sortKey="Nannmark, U" uniqKey="Nannmark U">U Nannmark</name>
</author>
<author><name sortKey="Samakovlis, C" uniqKey="Samakovlis C">C Samakovlis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Devine, Wp" uniqKey="Devine W">WP Devine</name>
</author>
<author><name sortKey="Lubarsky, B" uniqKey="Lubarsky B">B Lubarsky</name>
</author>
<author><name sortKey="Shaw, K" uniqKey="Shaw K">K Shaw</name>
</author>
<author><name sortKey="Luschnig, S" uniqKey="Luschnig S">S Luschnig</name>
</author>
<author><name sortKey="Messina, L" uniqKey="Messina L">L Messina</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jazwinska, A" uniqKey="Jazwinska A">A Jazwinska</name>
</author>
<author><name sortKey="Ribeiro, C" uniqKey="Ribeiro C">C Ribeiro</name>
</author>
<author><name sortKey="Affolter, M" uniqKey="Affolter M">M Affolter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dong, B" uniqKey="Dong B">B Dong</name>
</author>
<author><name sortKey="Hannezo, E" uniqKey="Hannezo E">E Hannezo</name>
</author>
<author><name sortKey="Hayashi, S" uniqKey="Hayashi S">S Hayashi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bilandzic, M" uniqKey="Bilandzic M">M Bilandzic</name>
</author>
<author><name sortKey="Stenvers, Kl" uniqKey="Stenvers K">KL Stenvers</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rampoldi, L" uniqKey="Rampoldi L">L Rampoldi</name>
</author>
<author><name sortKey="Scolari, F" uniqKey="Scolari F">F Scolari</name>
</author>
<author><name sortKey="Amoroso, A" uniqKey="Amoroso A">A Amoroso</name>
</author>
<author><name sortKey="Ghiggeri, G" uniqKey="Ghiggeri G">G Ghiggeri</name>
</author>
<author><name sortKey="Devuyst, O" uniqKey="Devuyst O">O Devuyst</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Roggenbuck, D" uniqKey="Roggenbuck D">D Roggenbuck</name>
</author>
<author><name sortKey="Hausdorf, G" uniqKey="Hausdorf G">G Hausdorf</name>
</author>
<author><name sortKey="Martinez Gamboa, L" uniqKey="Martinez Gamboa L">L Martinez-Gamboa</name>
</author>
<author><name sortKey="Reinhold, D" uniqKey="Reinhold D">D Reinhold</name>
</author>
<author><name sortKey="Buttner, T" uniqKey="Buttner T">T Buttner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ten Dijke, P" uniqKey="Ten Dijke P">P ten Dijke</name>
</author>
<author><name sortKey="Goumans, Mj" uniqKey="Goumans M">MJ Goumans</name>
</author>
<author><name sortKey="Pardali, E" uniqKey="Pardali E">E Pardali</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sundaram, Mv" uniqKey="Sundaram M">MV Sundaram</name>
</author>
<author><name sortKey="Cohen, Jd" uniqKey="Cohen J">JD Cohen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bar, T" uniqKey="Bar T">T Bar</name>
</author>
<author><name sortKey="Guldner, Fh" uniqKey="Guldner F">FH Guldner</name>
</author>
<author><name sortKey="Wolff, Jr" uniqKey="Wolff J">JR Wolff</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Govani, Fs" uniqKey="Govani F">FS Govani</name>
</author>
<author><name sortKey="Shovlin, Cl" uniqKey="Shovlin C">CL Shovlin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Draheim, Km" uniqKey="Draheim K">KM Draheim</name>
</author>
<author><name sortKey="Fisher, Os" uniqKey="Fisher O">OS Fisher</name>
</author>
<author><name sortKey="Boggon, Tj" uniqKey="Boggon T">TJ Boggon</name>
</author>
<author><name sortKey="Calderwood, Da" uniqKey="Calderwood D">DA Calderwood</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Haffner, C" uniqKey="Haffner C">C Haffner</name>
</author>
<author><name sortKey="Malik, R" uniqKey="Malik R">R Malik</name>
</author>
<author><name sortKey="Dichgans, M" uniqKey="Dichgans M">M Dichgans</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Feihl, F" uniqKey="Feihl F">F Feihl</name>
</author>
<author><name sortKey="Liaudet, L" uniqKey="Liaudet L">L Liaudet</name>
</author>
<author><name sortKey="Levy, Bi" uniqKey="Levy B">BI Levy</name>
</author>
<author><name sortKey="Waeber, B" uniqKey="Waeber B">B Waeber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Perez Gil, J" uniqKey="Perez Gil J">J Perez-Gil</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Buechner, M" uniqKey="Buechner M">M Buechner</name>
</author>
<author><name sortKey="Hall, Dh" uniqKey="Hall D">DH Hall</name>
</author>
<author><name sortKey="Bhatt, H" uniqKey="Bhatt H">H Bhatt</name>
</author>
<author><name sortKey="Hedgecock, Em" uniqKey="Hedgecock E">EM Hedgecock</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mancuso, Vp" uniqKey="Mancuso V">VP Mancuso</name>
</author>
<author><name sortKey="Parry, Jm" uniqKey="Parry J">JM Parry</name>
</author>
<author><name sortKey="Storer, L" uniqKey="Storer L">L Storer</name>
</author>
<author><name sortKey="Poggioli, C" uniqKey="Poggioli C">C Poggioli</name>
</author>
<author><name sortKey="Nguyen, Kc" uniqKey="Nguyen K">KC Nguyen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nelson, Fk" uniqKey="Nelson F">FK Nelson</name>
</author>
<author><name sortKey="Albert, Ps" uniqKey="Albert P">PS Albert</name>
</author>
<author><name sortKey="Riddle, Dl" uniqKey="Riddle D">DL Riddle</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Page, Ap" uniqKey="Page A">AP Page</name>
</author>
<author><name sortKey="Johnstone, Il" uniqKey="Johnstone I">IL Johnstone</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kalamajski, S" uniqKey="Kalamajski S">S Kalamajski</name>
</author>
<author><name sortKey="Oldberg, A" uniqKey="Oldberg A">A Oldberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jones, Sj" uniqKey="Jones S">SJ Jones</name>
</author>
<author><name sortKey="Baillie, Dl" uniqKey="Baillie D">DL Baillie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sundaram, Mv" uniqKey="Sundaram M">MV Sundaram</name>
</author>
<author><name sortKey="Buechner, M" uniqKey="Buechner M">M Buechner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nelson, Fk" uniqKey="Nelson F">FK Nelson</name>
</author>
<author><name sortKey="Riddle, Dl" uniqKey="Riddle D">DL Riddle</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stone, Ce" uniqKey="Stone C">CE Stone</name>
</author>
<author><name sortKey="Hall, Dh" uniqKey="Hall D">DH Hall</name>
</author>
<author><name sortKey="Sundaram, Mv" uniqKey="Sundaram M">MV Sundaram</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Abdus Saboor, I" uniqKey="Abdus Saboor I">I Abdus-Saboor</name>
</author>
<author><name sortKey="Mancuso, Vp" uniqKey="Mancuso V">VP Mancuso</name>
</author>
<author><name sortKey="Murray, Ji" uniqKey="Murray J">JI Murray</name>
</author>
<author><name sortKey="Palozola, K" uniqKey="Palozola K">K Palozola</name>
</author>
<author><name sortKey="Norris, C" uniqKey="Norris C">C Norris</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tordai, H" uniqKey="Tordai H">H Tordai</name>
</author>
<author><name sortKey="Banyai, L" uniqKey="Banyai L">L Banyai</name>
</author>
<author><name sortKey="Patthy, L" uniqKey="Patthy L">L Patthy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fernandes, I" uniqKey="Fernandes I">I Fernandes</name>
</author>
<author><name sortKey="Chanut Delalande, H" uniqKey="Chanut Delalande H">H Chanut-Delalande</name>
</author>
<author><name sortKey="Ferrer, P" uniqKey="Ferrer P">P Ferrer</name>
</author>
<author><name sortKey="Latapie, Y" uniqKey="Latapie Y">Y Latapie</name>
</author>
<author><name sortKey="Waltzer, L" uniqKey="Waltzer L">L Waltzer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jovine, L" uniqKey="Jovine L">L Jovine</name>
</author>
<author><name sortKey="Qi, H" uniqKey="Qi H">H Qi</name>
</author>
<author><name sortKey="Williams, Z" uniqKey="Williams Z">Z Williams</name>
</author>
<author><name sortKey="Litscher, E" uniqKey="Litscher E">E Litscher</name>
</author>
<author><name sortKey="Wassarman, Pm" uniqKey="Wassarman P">PM Wassarman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sapio, Mr" uniqKey="Sapio M">MR Sapio</name>
</author>
<author><name sortKey="Hilliard, Ma" uniqKey="Hilliard M">MA Hilliard</name>
</author>
<author><name sortKey="Cermola, M" uniqKey="Cermola M">M Cermola</name>
</author>
<author><name sortKey="Favre, R" uniqKey="Favre R">R Favre</name>
</author>
<author><name sortKey="Bazzicalupo, P" uniqKey="Bazzicalupo P">P Bazzicalupo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zielinska, Df" uniqKey="Zielinska D">DF Zielinska</name>
</author>
<author><name sortKey="Gnad, F" uniqKey="Gnad F">F Gnad</name>
</author>
<author><name sortKey="Schropp, K" uniqKey="Schropp K">K Schropp</name>
</author>
<author><name sortKey="Wisniewski, Jr" uniqKey="Wisniewski J">JR Wisniewski</name>
</author>
<author><name sortKey="Mann, M" uniqKey="Mann M">M Mann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Letunic, I" uniqKey="Letunic I">I Letunic</name>
</author>
<author><name sortKey="Doerks, T" uniqKey="Doerks T">T Doerks</name>
</author>
<author><name sortKey="Bork, P" uniqKey="Bork P">P Bork</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eisenhaber, B" uniqKey="Eisenhaber B">B Eisenhaber</name>
</author>
<author><name sortKey="Bork, P" uniqKey="Bork P">P Bork</name>
</author>
<author><name sortKey="Eisenhaber, F" uniqKey="Eisenhaber F">F Eisenhaber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brunati, M" uniqKey="Brunati M">M Brunati</name>
</author>
<author><name sortKey="Perucca, S" uniqKey="Perucca S">S Perucca</name>
</author>
<author><name sortKey="Han, L" uniqKey="Han L">L Han</name>
</author>
<author><name sortKey="Cattaneo, A" uniqKey="Cattaneo A">A Cattaneo</name>
</author>
<author><name sortKey="Consolato, F" uniqKey="Consolato F">F Consolato</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jovine, L" uniqKey="Jovine L">L Jovine</name>
</author>
<author><name sortKey="Qi, H" uniqKey="Qi H">H Qi</name>
</author>
<author><name sortKey="Williams, Z" uniqKey="Williams Z">Z Williams</name>
</author>
<author><name sortKey="Litscher, Es" uniqKey="Litscher E">ES Litscher</name>
</author>
<author><name sortKey="Wassarman, Pm" uniqKey="Wassarman P">PM Wassarman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lin, Sj" uniqKey="Lin S">SJ Lin</name>
</author>
<author><name sortKey="Hu, Y" uniqKey="Hu Y">Y Hu</name>
</author>
<author><name sortKey="Zhu, J" uniqKey="Zhu J">J Zhu</name>
</author>
<author><name sortKey="Woodruff, Tk" uniqKey="Woodruff T">TK Woodruff</name>
</author>
<author><name sortKey="Jardetzky, Ts" uniqKey="Jardetzky T">TS Jardetzky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schaeffer, C" uniqKey="Schaeffer C">C Schaeffer</name>
</author>
<author><name sortKey="Santambrogio, S" uniqKey="Santambrogio S">S Santambrogio</name>
</author>
<author><name sortKey="Perucca, S" uniqKey="Perucca S">S Perucca</name>
</author>
<author><name sortKey="Casari, G" uniqKey="Casari G">G Casari</name>
</author>
<author><name sortKey="Rampoldi, L" uniqKey="Rampoldi L">L Rampoldi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liegeois, S" uniqKey="Liegeois S">S Liegeois</name>
</author>
<author><name sortKey="Benedetto, A" uniqKey="Benedetto A">A Benedetto</name>
</author>
<author><name sortKey="Michaux, G" uniqKey="Michaux G">G Michaux</name>
</author>
<author><name sortKey="Belliard, G" uniqKey="Belliard G">G Belliard</name>
</author>
<author><name sortKey="Labouesse, M" uniqKey="Labouesse M">M Labouesse</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Parry, Jm" uniqKey="Parry J">JM Parry</name>
</author>
<author><name sortKey="Sundaram, Mv" uniqKey="Sundaram M">MV Sundaram</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Priess, Jr" uniqKey="Priess J">JR Priess</name>
</author>
<author><name sortKey="Hirsh, Di" uniqKey="Hirsh D">DI Hirsh</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chisholm, Ad" uniqKey="Chisholm A">AD Chisholm</name>
</author>
<author><name sortKey="Hsiao, Ti" uniqKey="Hsiao T">TI Hsiao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Herman, T" uniqKey="Herman T">T Herman</name>
</author>
<author><name sortKey="Hartwieg, E" uniqKey="Hartwieg E">E Hartwieg</name>
</author>
<author><name sortKey="Horvitz, Hr" uniqKey="Horvitz H">HR Horvitz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Farooqui, S" uniqKey="Farooqui S">S Farooqui</name>
</author>
<author><name sortKey="Pellegrino, Mw" uniqKey="Pellegrino M">MW Pellegrino</name>
</author>
<author><name sortKey="Rimann, I" uniqKey="Rimann I">I Rimann</name>
</author>
<author><name sortKey="Morf, Mk" uniqKey="Morf M">MK Morf</name>
</author>
<author><name sortKey="Muller, L" uniqKey="Muller L">L Muller</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Olson, Sk" uniqKey="Olson S">SK Olson</name>
</author>
<author><name sortKey="Greenan, G" uniqKey="Greenan G">G Greenan</name>
</author>
<author><name sortKey="Desai, A" uniqKey="Desai A">A Desai</name>
</author>
<author><name sortKey="Muller Reichert, T" uniqKey="Muller Reichert T">T Muller-Reichert</name>
</author>
<author><name sortKey="Oegema, K" uniqKey="Oegema K">K Oegema</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mizuguchi, S" uniqKey="Mizuguchi S">S Mizuguchi</name>
</author>
<author><name sortKey="Uyama, T" uniqKey="Uyama T">T Uyama</name>
</author>
<author><name sortKey="Kitagawa, H" uniqKey="Kitagawa H">H Kitagawa</name>
</author>
<author><name sortKey="Nomura, Kh" uniqKey="Nomura K">KH Nomura</name>
</author>
<author><name sortKey="Dejima, K" uniqKey="Dejima K">K Dejima</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kelley, M" uniqKey="Kelley M">M Kelley</name>
</author>
<author><name sortKey="Yochem, J" uniqKey="Yochem J">J Yochem</name>
</author>
<author><name sortKey="Krieg, M" uniqKey="Krieg M">M Krieg</name>
</author>
<author><name sortKey="Calixto, A" uniqKey="Calixto A">A Calixto</name>
</author>
<author><name sortKey="Heiman, Mg" uniqKey="Heiman M">MG Heiman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Aronson, De" uniqKey="Aronson D">DE Aronson</name>
</author>
<author><name sortKey="Costantini, Lm" uniqKey="Costantini L">LM Costantini</name>
</author>
<author><name sortKey="Snapp, El" uniqKey="Snapp E">EL Snapp</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Han, L" uniqKey="Han L">L Han</name>
</author>
<author><name sortKey="Monne, M" uniqKey="Monne M">M Monne</name>
</author>
<author><name sortKey="Okumura, H" uniqKey="Okumura H">H Okumura</name>
</author>
<author><name sortKey="Schwend, T" uniqKey="Schwend T">T Schwend</name>
</author>
<author><name sortKey="Cherry, Al" uniqKey="Cherry A">AL Cherry</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Costa, M" uniqKey="Costa M">M Costa</name>
</author>
<author><name sortKey="Draper, Bw" uniqKey="Draper B">BW Draper</name>
</author>
<author><name sortKey="Priess, Jr" uniqKey="Priess J">JR Priess</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hendriks, Gj" uniqKey="Hendriks G">GJ Hendriks</name>
</author>
<author><name sortKey="Gaidatzis, D" uniqKey="Gaidatzis D">D Gaidatzis</name>
</author>
<author><name sortKey="Aeschimann, F" uniqKey="Aeschimann F">F Aeschimann</name>
</author>
<author><name sortKey="Grosshans, H" uniqKey="Grosshans H">H Grosshans</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cox, Gn" uniqKey="Cox G">GN Cox</name>
</author>
<author><name sortKey="Hirsh, D" uniqKey="Hirsh D">D Hirsh</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bender, Am" uniqKey="Bender A">AM Bender</name>
</author>
<author><name sortKey="Kirienko, Nv" uniqKey="Kirienko N">NV Kirienko</name>
</author>
<author><name sortKey="Olson, Sk" uniqKey="Olson S">SK Olson</name>
</author>
<author><name sortKey="Esko, Jd" uniqKey="Esko J">JD Esko</name>
</author>
<author><name sortKey="Fay, Ds" uniqKey="Fay D">DS Fay</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jentoft, N" uniqKey="Jentoft N">N Jentoft</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shogren, R" uniqKey="Shogren R">R Shogren</name>
</author>
<author><name sortKey="Gerken, Ta" uniqKey="Gerken T">TA Gerken</name>
</author>
<author><name sortKey="Jentoft, N" uniqKey="Jentoft N">N Jentoft</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jimenez Movilla, M" uniqKey="Jimenez Movilla M">M Jimenez-Movilla</name>
</author>
<author><name sortKey="Dean, J" uniqKey="Dean J">J Dean</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lillehoj, Ep" uniqKey="Lillehoj E">EP Lillehoj</name>
</author>
<author><name sortKey="Kato, K" uniqKey="Kato K">K Kato</name>
</author>
<author><name sortKey="Lu, W" uniqKey="Lu W">W Lu</name>
</author>
<author><name sortKey="Kim, Kc" uniqKey="Kim K">KC Kim</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Monne, M" uniqKey="Monne M">M Monne</name>
</author>
<author><name sortKey="Han, L" uniqKey="Han L">L Han</name>
</author>
<author><name sortKey="Schwend, T" uniqKey="Schwend T">T Schwend</name>
</author>
<author><name sortKey="Burendahl, S" uniqKey="Burendahl S">S Burendahl</name>
</author>
<author><name sortKey="Jovine, L" uniqKey="Jovine L">L Jovine</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilkin, Mb" uniqKey="Wilkin M">MB Wilkin</name>
</author>
<author><name sortKey="Becker, Mn" uniqKey="Becker M">MN Becker</name>
</author>
<author><name sortKey="Mulvey, D" uniqKey="Mulvey D">D Mulvey</name>
</author>
<author><name sortKey="Phan, I" uniqKey="Phan I">I Phan</name>
</author>
<author><name sortKey="Chao, A" uniqKey="Chao A">A Chao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcallister, Ka" uniqKey="Mcallister K">KA McAllister</name>
</author>
<author><name sortKey="Grogg, Km" uniqKey="Grogg K">KM Grogg</name>
</author>
<author><name sortKey="Johnson, Dw" uniqKey="Johnson D">DW Johnson</name>
</author>
<author><name sortKey="Gallione, Cj" uniqKey="Gallione C">CJ Gallione</name>
</author>
<author><name sortKey="Baldwin, Ma" uniqKey="Baldwin M">MA Baldwin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tual Chalot, S" uniqKey="Tual Chalot S">S Tual-Chalot</name>
</author>
<author><name sortKey="Oh, Sp" uniqKey="Oh S">SP Oh</name>
</author>
<author><name sortKey="Arthur, Hm" uniqKey="Arthur H">HM Arthur</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chung, Yd" uniqKey="Chung Y">YD Chung</name>
</author>
<author><name sortKey="Zhu, J" uniqKey="Zhu J">J Zhu</name>
</author>
<author><name sortKey="Han, Y" uniqKey="Han Y">Y Han</name>
</author>
<author><name sortKey="Kernan, Mj" uniqKey="Kernan M">MJ Kernan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Andres, M" uniqKey="Andres M">M Andres</name>
</author>
<author><name sortKey="Turiegano, E" uniqKey="Turiegano E">E Turiegano</name>
</author>
<author><name sortKey="Gopfert, Mc" uniqKey="Gopfert M">MC Gopfert</name>
</author>
<author><name sortKey="Canal, I" uniqKey="Canal I">I Canal</name>
</author>
<author><name sortKey="Torroja, L" uniqKey="Torroja L">L Torroja</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Krause, C" uniqKey="Krause C">C Krause</name>
</author>
<author><name sortKey="Wolf, C" uniqKey="Wolf C">C Wolf</name>
</author>
<author><name sortKey="Hemphala, J" uniqKey="Hemphala J">J Hemphala</name>
</author>
<author><name sortKey="Samakovlis, C" uniqKey="Samakovlis C">C Samakovlis</name>
</author>
<author><name sortKey="Schuh, R" uniqKey="Schuh R">R Schuh</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Swanson, Le" uniqKey="Swanson L">LE Swanson</name>
</author>
<author><name sortKey="Yu, M" uniqKey="Yu M">M Yu</name>
</author>
<author><name sortKey="Nelson, Ks" uniqKey="Nelson K">KS Nelson</name>
</author>
<author><name sortKey="Laprise, P" uniqKey="Laprise P">P Laprise</name>
</author>
<author><name sortKey="Tepass, U" uniqKey="Tepass U">U Tepass</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schmidt Ott, Km" uniqKey="Schmidt Ott K">KM Schmidt-Ott</name>
</author>
<author><name sortKey="Mori, K" uniqKey="Mori K">K Mori</name>
</author>
<author><name sortKey="Li, Jy" uniqKey="Li J">JY Li</name>
</author>
<author><name sortKey="Kalandadze, A" uniqKey="Kalandadze A">A Kalandadze</name>
</author>
<author><name sortKey="Cohen, Dj" uniqKey="Cohen D">DJ Cohen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bernascone, I" uniqKey="Bernascone I">I Bernascone</name>
</author>
<author><name sortKey="Janas, S" uniqKey="Janas S">S Janas</name>
</author>
<author><name sortKey="Ikehata, M" uniqKey="Ikehata M">M Ikehata</name>
</author>
<author><name sortKey="Trudu, M" uniqKey="Trudu M">M Trudu</name>
</author>
<author><name sortKey="Corbelli, A" uniqKey="Corbelli A">A Corbelli</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brenner, S" uniqKey="Brenner S">S Brenner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Edgley, Ml" uniqKey="Edgley M">ML Edgley</name>
</author>
<author><name sortKey="Baillie, Dl" uniqKey="Baillie D">DL Baillie</name>
</author>
<author><name sortKey="Riddle, Dl" uniqKey="Riddle D">DL Riddle</name>
</author>
<author><name sortKey="Rose, Am" uniqKey="Rose A">AM Rose</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Koppen, M" uniqKey="Koppen M">M Koppen</name>
</author>
<author><name sortKey="Simske, Js" uniqKey="Simske J">JS Simske</name>
</author>
<author><name sortKey="Sims, Pa" uniqKey="Sims P">PA Sims</name>
</author>
<author><name sortKey="Firestein, Bl" uniqKey="Firestein B">BL Firestein</name>
</author>
<author><name sortKey="Hall, Dh" uniqKey="Hall D">DH Hall</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hunt Newbury, R" uniqKey="Hunt Newbury R">R Hunt-Newbury</name>
</author>
<author><name sortKey="Viveiros, R" uniqKey="Viveiros R">R Viveiros</name>
</author>
<author><name sortKey="Johnsen, R" uniqKey="Johnsen R">R Johnsen</name>
</author>
<author><name sortKey="Mah, A" uniqKey="Mah A">A Mah</name>
</author>
<author><name sortKey="Anastas, D" uniqKey="Anastas D">D Anastas</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Minevich, G" uniqKey="Minevich G">G Minevich</name>
</author>
<author><name sortKey="Park, Ds" uniqKey="Park D">DS Park</name>
</author>
<author><name sortKey="Blankenberg, D" uniqKey="Blankenberg D">D Blankenberg</name>
</author>
<author><name sortKey="Poole, Rj" uniqKey="Poole R">RJ Poole</name>
</author>
<author><name sortKey="Hobert, O" uniqKey="Hobert O">O Hobert</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Johnson, Ad" uniqKey="Johnson A">AD Johnson</name>
</author>
<author><name sortKey="Fitzsimmons, D" uniqKey="Fitzsimmons D">D Fitzsimmons</name>
</author>
<author><name sortKey="Hagman, J" uniqKey="Hagman J">J Hagman</name>
</author>
<author><name sortKey="Chamberlin, Hm" uniqKey="Chamberlin H">HM Chamberlin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gilleard, Js" uniqKey="Gilleard J">JS Gilleard</name>
</author>
<author><name sortKey="Barry, Jd" uniqKey="Barry J">JD Barry</name>
</author>
<author><name sortKey="Johnstone, Il" uniqKey="Johnstone I">IL Johnstone</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mano, I" uniqKey="Mano I">I Mano</name>
</author>
<author><name sortKey="Straud, S" uniqKey="Straud S">S Straud</name>
</author>
<author><name sortKey="Driscoll, M" uniqKey="Driscoll M">M Driscoll</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Okkema, Pg" uniqKey="Okkema P">PG Okkema</name>
</author>
<author><name sortKey="Harrison, Sw" uniqKey="Harrison S">SW Harrison</name>
</author>
<author><name sortKey="Plunger, V" uniqKey="Plunger V">V Plunger</name>
</author>
<author><name sortKey="Aryana, A" uniqKey="Aryana A">A Aryana</name>
</author>
<author><name sortKey="Fire, A" uniqKey="Fire A">A Fire</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sarov, M" uniqKey="Sarov M">M Sarov</name>
</author>
<author><name sortKey="Murray, Ji" uniqKey="Murray J">JI Murray</name>
</author>
<author><name sortKey="Schanze, K" uniqKey="Schanze K">K Schanze</name>
</author>
<author><name sortKey="Pozniakovski, A" uniqKey="Pozniakovski A">A Pozniakovski</name>
</author>
<author><name sortKey="Niu, W" uniqKey="Niu W">W Niu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hall, Dh" uniqKey="Hall D">DH Hall</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Weimer, Rm" uniqKey="Weimer R">RM Weimer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Steentoft, C" uniqKey="Steentoft C">C Steentoft</name>
</author>
<author><name sortKey="Vakhrushev, Sy" uniqKey="Vakhrushev S">SY Vakhrushev</name>
</author>
<author><name sortKey="Joshi, Hj" uniqKey="Joshi H">HJ Joshi</name>
</author>
<author><name sortKey="Kong, Y" uniqKey="Kong Y">Y Kong</name>
</author>
<author><name sortKey="Vester Christensen, Mb" uniqKey="Vester Christensen M">MB Vester-Christensen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nakayama, K" uniqKey="Nakayama K">K Nakayama</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Suzuki, N" uniqKey="Suzuki N">N Suzuki</name>
</author>
<author><name sortKey="Toyoda, H" uniqKey="Toyoda H">H Toyoda</name>
</author>
<author><name sortKey="Sano, M" uniqKey="Sano M">M Sano</name>
</author>
<author><name sortKey="Nishiwaki, K" uniqKey="Nishiwaki K">K Nishiwaki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yachdav, G" uniqKey="Yachdav G">G Yachdav</name>
</author>
<author><name sortKey="Kloppmann, E" uniqKey="Kloppmann E">E Kloppmann</name>
</author>
<author><name sortKey="Kajan, L" uniqKey="Kajan L">L Kajan</name>
</author>
<author><name sortKey="Hecht, M" uniqKey="Hecht M">M Hecht</name>
</author>
<author><name sortKey="Goldberg, T" uniqKey="Goldberg T">T Goldberg</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
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</country>
<region><li>New Jersey</li>
<li>Pennsylvanie</li>
<li>État de New York</li>
</region>
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<tree><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Gill, Hasreet K" sort="Gill, Hasreet K" uniqKey="Gill H" first="Hasreet K." last="Gill">Hasreet K. Gill</name>
</region>
<name sortKey="Ayala Figueroa, Jesus" sort="Ayala Figueroa, Jesus" uniqKey="Ayala Figueroa J" first="Jesus" last="Ayala-Figueroa">Jesus Ayala-Figueroa</name>
<name sortKey="Bickard, Kevin" sort="Bickard, Kevin" uniqKey="Bickard K" first="Kevin" last="Bickard">Kevin Bickard</name>
<name sortKey="Cohen, Jennifer D" sort="Cohen, Jennifer D" uniqKey="Cohen J" first="Jennifer D." last="Cohen">Jennifer D. Cohen</name>
<name sortKey="Forman Rubinsky, Rachel" sort="Forman Rubinsky, Rachel" uniqKey="Forman Rubinsky R" first="Rachel" last="Forman-Rubinsky">Rachel Forman-Rubinsky</name>
<name sortKey="Hall, David H" sort="Hall, David H" uniqKey="Hall D" first="David H." last="Hall">David H. Hall</name>
<name sortKey="Parry, Jean M" sort="Parry, Jean M" uniqKey="Parry J" first="Jean M." last="Parry">Jean M. Parry</name>
<name sortKey="Parry, Jean M" sort="Parry, Jean M" uniqKey="Parry J" first="Jean M." last="Parry">Jean M. Parry</name>
<name sortKey="Poggioli, Corey" sort="Poggioli, Corey" uniqKey="Poggioli C" first="Corey" last="Poggioli">Corey Poggioli</name>
<name sortKey="Pu, Pu" sort="Pu, Pu" uniqKey="Pu P" first="Pu" last="Pu">Pu Pu</name>
<name sortKey="Sundaram, Meera V" sort="Sundaram, Meera V" uniqKey="Sundaram M" first="Meera V." last="Sundaram">Meera V. Sundaram</name>
</country>
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