Verrucous lesions arising in lymphedema and diabetic neuropathy: Elephantiasis nostras verrucosa or verrucous skin lesions on the feet of patients with diabetic neuropathy?
Identifieur interne : 000934 ( Main/Exploration ); précédent : 000933; suivant : 000935Verrucous lesions arising in lymphedema and diabetic neuropathy: Elephantiasis nostras verrucosa or verrucous skin lesions on the feet of patients with diabetic neuropathy?
Auteurs : Eri Hotta [Japon] ; Jun Asai [Japon] ; Yasutaro Okuzawa [Japon] ; Keiji Hanada [Japon] ; Tomoko Nomiyama [Japon] ; Hideya Takenaka [Japon] ; Norito Katoh [Japon]Source :
- The Journal of dermatology [ 1346-8138 ] ; 2016.
Descripteurs français
- KwdFr :
- Bas de contention, Humains, Hydrocortisone (administration et posologie), Lymphoedème (), Lymphoedème (anatomopathologie), Lymphoedème (étiologie), Mâle, Neuropathies diabétiques (), Neuropathies diabétiques (anatomopathologie), Pied diabétique (), Pied diabétique (anatomopathologie), Sujet âgé de 80 ans ou plus, Éléphantiasis (), Éléphantiasis (anatomopathologie), Éléphantiasis (étiologie).
- MESH :
- administration et posologie : Hydrocortisone.
- anatomopathologie : Lymphoedème, Neuropathies diabétiques, Pied diabétique, Éléphantiasis.
- étiologie : Lymphoedème, Éléphantiasis.
- Bas de contention, Humains, Lymphoedème, Mâle, Neuropathies diabétiques, Pied diabétique, Sujet âgé de 80 ans ou plus, Éléphantiasis.
English descriptors
- KwdEn :
- Aged, 80 and over, Diabetic Foot (complications), Diabetic Foot (pathology), Diabetic Neuropathies (complications), Diabetic Neuropathies (pathology), Elephantiasis (etiology), Elephantiasis (pathology), Elephantiasis (therapy), Humans, Hydrocortisone (administration & dosage), Lymphedema (etiology), Lymphedema (pathology), Lymphedema (therapy), Male, Stockings, Compression.
- MESH :
- chemical , administration & dosage : Hydrocortisone.
- complications : Diabetic Foot, Diabetic Neuropathies.
- etiology : Elephantiasis, Lymphedema.
- pathology : Diabetic Foot, Diabetic Neuropathies, Elephantiasis, Lymphedema.
- therapy : Elephantiasis, Lymphedema.
- Aged, 80 and over, Humans, Male, Stockings, Compression.
Abstract
Verrucous skin lesions on the feet in diabetic neuropathy (VSLDN) develop in areas with sensory loss in diabetic patients. Although various types of chronic stimulation, such as pressure or friction, are considered an important factor in the development of such lesions, the precise pathogenesis of VSLDN remains obscure, and there is currently no established treatment for this disease. Here, we present a case of VSLDN on the dorsum of the right foot. However, because lymphedema was also observed at the same site, this lesion could also be diagnosed as elephantiasis nostras verrucosa arising in diabetic neuropathy. The lesion was successfully treated with a combination of elastic stocking and mixed killed bacterial suspension and hydrocortisone ointment, which suggested that VSLDN might have been exacerbated by the pre-existing lymphedema. Because various types of chronic stimulation can trigger VSLDN, treatment plans should be devised on a case-by-case basis. Therefore, it is important to investigate the presence of factors that can induce or exacerbate chronic inflammatory stimulation, such as lymphedema in our case, in each patient with VSLDN.
DOI: 10.1111/1346-8138.13063
PubMed: 26281791
Affiliations:
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qualifier="administration & dosage" xml:lang="en"><term>Hydrocortisone</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Hydrocortisone</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Lymphoedème</term><term>Neuropathies diabétiques</term><term>Pied diabétique</term><term>Éléphantiasis</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Diabetic Foot</term><term>Diabetic Neuropathies</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Elephantiasis</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Diabetic Foot</term><term>Diabetic Neuropathies</term><term>Elephantiasis</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Elephantiasis</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term><term>Éléphantiasis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged, 80 and over</term><term>Humans</term><term>Male</term><term>Stockings, Compression</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Bas de contention</term><term>Humains</term><term>Lymphoedème</term><term>Mâle</term><term>Neuropathies diabétiques</term><term>Pied diabétique</term><term>Sujet âgé de 80 ans ou plus</term><term>Éléphantiasis</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Verrucous skin lesions on the feet in diabetic neuropathy (VSLDN) develop in areas with sensory loss in diabetic patients. Although various types of chronic stimulation, such as pressure or friction, are considered an important factor in the development of such lesions, the precise pathogenesis of VSLDN remains obscure, and there is currently no established treatment for this disease. Here, we present a case of VSLDN on the dorsum of the right foot. However, because lymphedema was also observed at the same site, this lesion could also be diagnosed as elephantiasis nostras verrucosa arising in diabetic neuropathy. The lesion was successfully treated with a combination of elastic stocking and mixed killed bacterial suspension and hydrocortisone ointment, which suggested that VSLDN might have been exacerbated by the pre-existing lymphedema. Because various types of chronic stimulation can trigger VSLDN, treatment plans should be devised on a case-by-case basis. Therefore, it is important to investigate the presence of factors that can induce or exacerbate chronic inflammatory stimulation, such as lymphedema in our case, in each patient with VSLDN.</div></front></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Hotta, Eri" sort="Hotta, Eri" uniqKey="Hotta E" first="Eri" last="Hotta">Eri Hotta</name></noRegion><name sortKey="Asai, Jun" sort="Asai, Jun" uniqKey="Asai J" first="Jun" last="Asai">Jun Asai</name><name sortKey="Hanada, Keiji" sort="Hanada, Keiji" uniqKey="Hanada K" first="Keiji" last="Hanada">Keiji Hanada</name><name sortKey="Katoh, Norito" sort="Katoh, Norito" uniqKey="Katoh N" first="Norito" last="Katoh">Norito Katoh</name><name sortKey="Nomiyama, Tomoko" sort="Nomiyama, Tomoko" uniqKey="Nomiyama T" first="Tomoko" last="Nomiyama">Tomoko Nomiyama</name><name sortKey="Okuzawa, Yasutaro" sort="Okuzawa, Yasutaro" uniqKey="Okuzawa Y" first="Yasutaro" last="Okuzawa">Yasutaro Okuzawa</name><name sortKey="Takenaka, Hideya" sort="Takenaka, Hideya" uniqKey="Takenaka H" first="Hideya" last="Takenaka">Hideya Takenaka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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