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Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy

Identifieur interne : 000161 ( Istex/Curation ); précédent : 000160; suivant : 000162

Common toxicity criteria: version 2.0. an improved reference for grading the acute effects of cancer treatment: impact on radiotherapy

Auteurs : Andy Trotti [États-Unis] ; Roger Byhardt [États-Unis] ; Joanne Stetz [États-Unis] ; Clement Gwede [États-Unis] ; Benjamin Corn [États-Unis] ; Karen Fu [États-Unis] ; Leonard Gunderson [États-Unis] ; Beryl Mccormick [États-Unis] ; Mitchell Morris [États-Unis] ; Tyvin Rich [États-Unis] ; William Shipley [États-Unis] ; Walter Curran [États-Unis]

Source :

RBID : ISTEX:036669930279CBD2A5ADDF9B4CF4F8CB7D9A7C21

English descriptors

Abstract

In 1997, the National Cancer Institute (NCI) led an effort to revise and expand the Common Toxicity Criteria (CTC) with the goal of integrating systemic agent, radiation, and surgical criteria into a comprehensive and standardized system. Representatives from the Radiation Therapy Oncology Group (RTOG) participated in this process in an effort to improve acute radiation related criteria and to achieve better clarity and consistency among modalities. CTC v. 2.0 replaces the previous NCI CTC and the RTOG Acute Radiation Morbidity Scoring Criteria and includes more than 260 individual adverse events with more than 100 of these applicable to acute radiation effects. One of the advantages of the revised criteria for radiation oncology is the opportunity to grade acute radiation effects not adequately captured under the previous RTOG system. A pilot study conducted by the RTOG indicated the new criteria are indeed more comprehensive and were preferred by research associates. CTC v. 2.0 represents an improvement in the evaluation and grading of acute toxicity for all modalities.

Url:
DOI: 10.1016/S0360-3016(99)00559-3

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ISTEX:036669930279CBD2A5ADDF9B4CF4F8CB7D9A7C21

Le document en format XML

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<div type="abstract" xml:lang="en">In 1997, the National Cancer Institute (NCI) led an effort to revise and expand the Common Toxicity Criteria (CTC) with the goal of integrating systemic agent, radiation, and surgical criteria into a comprehensive and standardized system. Representatives from the Radiation Therapy Oncology Group (RTOG) participated in this process in an effort to improve acute radiation related criteria and to achieve better clarity and consistency among modalities. CTC v. 2.0 replaces the previous NCI CTC and the RTOG Acute Radiation Morbidity Scoring Criteria and includes more than 260 individual adverse events with more than 100 of these applicable to acute radiation effects. One of the advantages of the revised criteria for radiation oncology is the opportunity to grade acute radiation effects not adequately captured under the previous RTOG system. A pilot study conducted by the RTOG indicated the new criteria are indeed more comprehensive and were preferred by research associates. CTC v. 2.0 represents an improvement in the evaluation and grading of acute toxicity for all modalities.</div>
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