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Management of soft tissue sarcoma

Identifieur interne : 000143 ( Istex/Corpus ); précédent : 000142; suivant : 000144

Management of soft tissue sarcoma

Auteurs : M. E. Pitcher ; S. Fish ; S. Thomas

Source :

RBID : ISTEX:03188AADB95347E856A2C88C9E551D3361A6BC90

Abstract

A total of 485 patients with a proven or suspected diagnosis of soft tissue sarcoma were referred over a 3‐year period. Of these, 61 were referred for opinion only and 424 for definitive treatment. Overall there were 223 patients with primary soft tissue sarcoma and 84 with recurrent sarcoma, 84 with benign soft tissue tumours and 22 with non‐soft tissue sarcoma malignancy; 11 patients were referred with known metastatic disease. The commonest benign tumours mimicking soft tissue sarcoma were fibromatosis and benign intermuscular or intramuscular lipoma. The malignant tumours suspected clinically of being soft tissue sarcoma were bone tumours, lymphoma and metastatic carcinoma. Of the 172 patients with primary soft tissue sarcoma referred with a proven diagnosis this had been established by excision biopsy in 94 and open incision biopsy in 48. By contrast, of those undiagnosed at referral, 44 of 51 patients with soft tissue sarcoma had the diagnosis made by Tru‐cut core biopsy. Amputation was performed in four of 165 patients with primary extremity soft tissue sarcoma and in five of 54 with recurrent extremity sarcoma, giving an overall amputation rate of 4 per cent. It is proposed that the amputation rate for extremity soft tissue sarcoma can be reduced by the use of reconstructive procedures, particularly myocutaneous flaps to the proximal limbs and limb girdles, and free vascularized flaps to sites distal to the midthigh and midarm.

Url:
DOI: 10.1002/bjs.1800810817

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ISTEX:03188AADB95347E856A2C88C9E551D3361A6BC90

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<affiliation>Department of Surgery, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK</affiliation>
<affiliation>Department of Surgery, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK</affiliation>
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<typeOfResource>text</typeOfResource>
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<publisher>John Wiley & Sons, Ltd.</publisher>
<place>
<placeTerm type="text">Bristol</placeTerm>
</place>
<dateIssued encoding="w3cdtf">1994-08</dateIssued>
<dateValid encoding="w3cdtf">1993-12-21</dateValid>
<copyrightDate encoding="w3cdtf">1994</copyrightDate>
</originInfo>
<language>
<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<extent unit="tables">4</extent>
<extent unit="references">27</extent>
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<abstract lang="en">A total of 485 patients with a proven or suspected diagnosis of soft tissue sarcoma were referred over a 3‐year period. Of these, 61 were referred for opinion only and 424 for definitive treatment. Overall there were 223 patients with primary soft tissue sarcoma and 84 with recurrent sarcoma, 84 with benign soft tissue tumours and 22 with non‐soft tissue sarcoma malignancy; 11 patients were referred with known metastatic disease. The commonest benign tumours mimicking soft tissue sarcoma were fibromatosis and benign intermuscular or intramuscular lipoma. The malignant tumours suspected clinically of being soft tissue sarcoma were bone tumours, lymphoma and metastatic carcinoma. Of the 172 patients with primary soft tissue sarcoma referred with a proven diagnosis this had been established by excision biopsy in 94 and open incision biopsy in 48. By contrast, of those undiagnosed at referral, 44 of 51 patients with soft tissue sarcoma had the diagnosis made by Tru‐cut core biopsy. Amputation was performed in four of 165 patients with primary extremity soft tissue sarcoma and in five of 54 with recurrent extremity sarcoma, giving an overall amputation rate of 4 per cent. It is proposed that the amputation rate for extremity soft tissue sarcoma can be reduced by the use of reconstructive procedures, particularly myocutaneous flaps to the proximal limbs and limb girdles, and free vascularized flaps to sites distal to the midthigh and midarm.</abstract>
<relatedItem type="host">
<titleInfo>
<title>British Journal of Surgery</title>
</titleInfo>
<titleInfo type="abbreviated">
<title>Br J Surg</title>
</titleInfo>
<genre type="journal">journal</genre>
<subject>
<genre>article-category</genre>
<topic>Original Article</topic>
</subject>
<identifier type="ISSN">0007-1323</identifier>
<identifier type="eISSN">1365-2168</identifier>
<identifier type="DOI">10.1002/(ISSN)1365-2168</identifier>
<identifier type="PublisherID">BJS</identifier>
<part>
<date>1994</date>
<detail type="volume">
<caption>vol.</caption>
<number>81</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>8</number>
</detail>
<extent unit="pages">
<start>1136</start>
<end>1139</end>
<total>4</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">03188AADB95347E856A2C88C9E551D3361A6BC90</identifier>
<identifier type="DOI">10.1002/bjs.1800810817</identifier>
<identifier type="ArticleID">BJS1800810817</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 1994 British Journal of Surgery Society Ltd.</accessCondition>
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<recordContentSource>WILEY</recordContentSource>
<recordOrigin>John Wiley & Sons, Ltd.</recordOrigin>
</recordInfo>
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