Lymphatic filariasis in Uganda: baseline investigations in Lira, Soroti and Katakwi districts
Identifieur interne : 002843 ( Istex/Checkpoint ); précédent : 002842; suivant : 002844Lymphatic filariasis in Uganda: baseline investigations in Lira, Soroti and Katakwi districts
Auteurs : Ambrose W. Onapa [Ouganda] ; Paul E. Simonsen [Danemark] ; Erling M. Pedersen [Danemark] ; David O. Okello [Ouganda]Source :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 2001.
Abstract
Baseline epidemiological investigations on lymphatic filariasis were conducted for the first time in Uganda in 3 communities in the districts of Lira (Alebtong area), Soroti (Lwala area) and Katakwi (Obalanga area), located to the north of Lake Kyoga at an altitude of 1000–1100 m above sea level. Individuals from the communities were examined, in April–August 1998, for Wuchereria bancrofti specific circulating antigen (by ICT card test), microfilaraemia (by counting chamber and stained blood-smear techniques) and chronic clinical manifestations of lymphatic filariasis. Endophilic mosquitoes were sampled and dissected for filarial larvae. Prevalences of circulating filarial antigen positivity were 29%, 18% and 30% in the Alebtong, Lwala and Obalanga communities, respectively. Microfilaria (mf) prevalences were 18%, 9% and 21%, and geometric mean mf intensities among mf-positive individuals were 306, 171 and 402 mf/mL blood, in the same communities. Examination of stained blood smears revealed mf of both W. bancrofti and Mansonella Perstans, but more than 80% of mf-positive individuals harboured the first of these parasites. Prevalences of hydrocoele in adult (⩾20 years) males were 28%, 7% and 17%, and prevalences of limb elephantiasis in adults were 9%, 4% and 4%, in the Alebtong, Lwala and Obalanga communities, respectively. Anopheles gambiae s.l. (mainly An. gambiae s.s.) and An. funestus were common in all 3 communities, and showed W. bancrofti infectivity rates of 1·1–1·7% and 1·3–2·9%, respectively. It is concluded that lymphatic filariasis is highly endemic in these high-altitude areas of Uganda, with An. gambiae s.l. and An. funestus being the main vectors.
Url:
DOI: 10.1016/S0035-9203(01)90145-2
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
ISTEX:EE2914883FDCCB002719F0247F634FF06BB7782BLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Lymphatic filariasis in Uganda: baseline investigations in Lira, Soroti and Katakwi districts</title>
<author><name sortKey="Onapa, Ambrose W" sort="Onapa, Ambrose W" uniqKey="Onapa A" first="Ambrose W." last="Onapa">Ambrose W. Onapa</name>
</author>
<author><name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name>
</author>
<author><name sortKey="Pedersen, Erling M" sort="Pedersen, Erling M" uniqKey="Pedersen E" first="Erling M." last="Pedersen">Erling M. Pedersen</name>
</author>
<author><name sortKey="Okello, David O" sort="Okello, David O" uniqKey="Okello D" first="David O." last="Okello">David O. Okello</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:EE2914883FDCCB002719F0247F634FF06BB7782B</idno>
<date when="2001" year="2001">2001</date>
<idno type="doi">10.1016/S0035-9203(01)90145-2</idno>
<idno type="url">https://api.istex.fr/document/EE2914883FDCCB002719F0247F634FF06BB7782B/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">006F68</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">006F68</idno>
<idno type="wicri:Area/Istex/Curation">006F68</idno>
<idno type="wicri:Area/Istex/Checkpoint">002843</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">002843</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Lymphatic filariasis in Uganda: baseline investigations in Lira, Soroti and Katakwi districts</title>
<author><name sortKey="Onapa, Ambrose W" sort="Onapa, Ambrose W" uniqKey="Onapa A" first="Ambrose W." last="Onapa">Ambrose W. Onapa</name>
<affiliation wicri:level="1"><country xml:lang="fr">Ouganda</country>
<wicri:regionArea>Vector Control Division, Ministry of Health, P.O. Box 1661, Kampala</wicri:regionArea>
<wicri:noRegion>Kampala</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name>
<affiliation></affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Danemark</country>
<wicri:regionArea>Danish Bilharziasis Laboratory, Jaegersborg Alle 1 D, 2920 Charlottenlund</wicri:regionArea>
<wicri:noRegion>2920 Charlottenlund</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">Danemark</country>
</affiliation>
</author>
<author><name sortKey="Pedersen, Erling M" sort="Pedersen, Erling M" uniqKey="Pedersen E" first="Erling M." last="Pedersen">Erling M. Pedersen</name>
<affiliation wicri:level="1"><country xml:lang="fr">Danemark</country>
<wicri:regionArea>Danish Bilharziasis Laboratory, Jaegersborg Alle 1 D, 2920 Charlottenlund</wicri:regionArea>
<wicri:noRegion>2920 Charlottenlund</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Okello, David O" sort="Okello, David O" uniqKey="Okello D" first="David O." last="Okello">David O. Okello</name>
<affiliation wicri:level="1"><country xml:lang="fr">Ouganda</country>
<wicri:regionArea>Clinical Epidemiology Unit, Makerere University Medical School, P. O. Box 7072, Kampala</wicri:regionArea>
<wicri:noRegion>Kampala</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Transactions of the Royal Society of Tropical Medicine and Hygiene</title>
<title level="j" type="abbrev">TRSTMH</title>
<idno type="ISSN">0035-9203</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="2001">2001</date>
<biblScope unit="volume">95</biblScope>
<biblScope unit="issue">2</biblScope>
<biblScope unit="page" from="161">161</biblScope>
<biblScope unit="page" to="167">167</biblScope>
</imprint>
<idno type="ISSN">0035-9203</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0035-9203</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Baseline epidemiological investigations on lymphatic filariasis were conducted for the first time in Uganda in 3 communities in the districts of Lira (Alebtong area), Soroti (Lwala area) and Katakwi (Obalanga area), located to the north of Lake Kyoga at an altitude of 1000–1100 m above sea level. Individuals from the communities were examined, in April–August 1998, for Wuchereria bancrofti specific circulating antigen (by ICT card test), microfilaraemia (by counting chamber and stained blood-smear techniques) and chronic clinical manifestations of lymphatic filariasis. Endophilic mosquitoes were sampled and dissected for filarial larvae. Prevalences of circulating filarial antigen positivity were 29%, 18% and 30% in the Alebtong, Lwala and Obalanga communities, respectively. Microfilaria (mf) prevalences were 18%, 9% and 21%, and geometric mean mf intensities among mf-positive individuals were 306, 171 and 402 mf/mL blood, in the same communities. Examination of stained blood smears revealed mf of both W. bancrofti and Mansonella Perstans, but more than 80% of mf-positive individuals harboured the first of these parasites. Prevalences of hydrocoele in adult (⩾20 years) males were 28%, 7% and 17%, and prevalences of limb elephantiasis in adults were 9%, 4% and 4%, in the Alebtong, Lwala and Obalanga communities, respectively. Anopheles gambiae s.l. (mainly An. gambiae s.s.) and An. funestus were common in all 3 communities, and showed W. bancrofti infectivity rates of 1·1–1·7% and 1·3–2·9%, respectively. It is concluded that lymphatic filariasis is highly endemic in these high-altitude areas of Uganda, with An. gambiae s.l. and An. funestus being the main vectors.</div>
</front>
</TEI>
<affiliations><list><country><li>Danemark</li>
<li>Ouganda</li>
</country>
</list>
<tree><country name="Ouganda"><noRegion><name sortKey="Onapa, Ambrose W" sort="Onapa, Ambrose W" uniqKey="Onapa A" first="Ambrose W." last="Onapa">Ambrose W. Onapa</name>
</noRegion>
<name sortKey="Okello, David O" sort="Okello, David O" uniqKey="Okello D" first="David O." last="Okello">David O. Okello</name>
</country>
<country name="Danemark"><noRegion><name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name>
</noRegion>
<name sortKey="Pedersen, Erling M" sort="Pedersen, Erling M" uniqKey="Pedersen E" first="Erling M." last="Pedersen">Erling M. Pedersen</name>
<name sortKey="Simonsen, Paul E" sort="Simonsen, Paul E" uniqKey="Simonsen P" first="Paul E." last="Simonsen">Paul E. Simonsen</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Istex/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002843 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 002843 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Istex |étape= Checkpoint |type= RBID |clé= ISTEX:EE2914883FDCCB002719F0247F634FF06BB7782B |texte= Lymphatic filariasis in Uganda: baseline investigations in Lira, Soroti and Katakwi districts }}
This area was generated with Dilib version V0.6.31. |