Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls
Identifieur interne : 000156 ( PascalFrancis/Corpus ); précédent : 000155; suivant : 000157Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls
Auteurs : William Ondo ; Deborah Warrior ; Averell Overby ; Janine Calmes ; Nancy Hendersen ; Sharon Olson ; Joseph JankovicSource :
- Archives of neurology : (Chicago) [ 0003-9942 ] ; 2000.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder that is frequently mistaken for Parkinson's disease (PD) in its early stages. Objective: To compare balance measures using computerized posturography in patients with early PSP and early PD. Methods: We performed computerized posturography (SMART Balance Master; NeuroCom International, Inc, Clackamas, Ore) in 20 patients with clinically diagnosed mild to moderate PSP (ambulatory) and compared results with those from 20 patients with PD of similar age and disease duration who were not receiving medications, and from 20 healthy age- and sex-matched controls. Sensory organization testing (SOT), limits of stability (LOS), and toes-up perturbations (4° at 50° per second) were tested while receiving and not receiving a combination of oral carbidopa (25 mg) and levodopa (250 mg) in the PSP group. Clinical assessment included Unified Parkinson's Disease Rating Scale, Performance-oriented assessments, and functional reach. Results: When compared with the PD and control groups, total LOS time (P<.001) and path sway (P<.001) were significantly prolonged in PSP. Total SOT showed significantly worse scores in PSP compared with PD and control groups (F2.57=29.6; P<.001). Univariate follow-up tests comparing PSP and PD showed differences in the following conditions: eyes open and visual sway (P=.003), eyes open and platform sway (P=.003), eyes closed and platform sway (P<.001), and eyes open and platform and visual sway (P<.001), Medium- and long-latency responses to perturbation were similar, but a larger number in the PSP group lacked short-latency responses (x2=11.3; P=.002). Levodopa administration did not significantly improve any aspect of posturography testing in PSP. In differentiating PSP from PD, LOS time and SOT condition of eyes open and platform and visual sway were nearly 100% sensitive and 100% specific (canonical correlation, 0.91). Conclusions: Computerized posturography testing reliably differentiated early PSP from early PD and age-matched controls. The PSP group demonstrated severely contracted limits of stability with probable deficits in motor programming. Results of SOT in PSP suggested a vestibular pattern and overreliance on visual cues, even when incorrect. The absence of short-latency responses (monosynaptic reflex arch) suggests an additional disturbance in the spinal cord or peripheral nervous system.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
|
|---|
Format Inist (serveur)
| NO : | PASCAL 00-0520598 INIST |
|---|---|
| ET : | Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls |
| AU : | ONDO (William); WARRIOR (Deborah); OVERBY (Averell); CALMES (Janine); HENDERSEN (Nancy); OLSON (Sharon); JANKOVIC (Joseph) |
| AF : | Department of Neurology, Baylor College of Medicine/Houston, Tex/Etats-Unis (1 aut., 7 aut.); School of Physical Therapy, Texas Women's University/Denton/Etats-Unis (2 aut., 4 aut., 6 aut.); Department of Physical Therapy, Ohio University School of Medicine/Athens/Etats-Unis (3 aut.); Physical Therapy Section, Madigan Army Medical Center/Tacoma, Wash/Etats-Unis (5 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | Archives of neurology : (Chicago); ISSN 0003-9942; Coden ARNEAS; Etats-Unis; Da. 2000; Vol. 57; No. 10; Pp. 1464-1469; Bibl. 28 ref. |
| LA : | Anglais |
| EA : | Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder that is frequently mistaken for Parkinson's disease (PD) in its early stages. Objective: To compare balance measures using computerized posturography in patients with early PSP and early PD. Methods: We performed computerized posturography (SMART Balance Master; NeuroCom International, Inc, Clackamas, Ore) in 20 patients with clinically diagnosed mild to moderate PSP (ambulatory) and compared results with those from 20 patients with PD of similar age and disease duration who were not receiving medications, and from 20 healthy age- and sex-matched controls. Sensory organization testing (SOT), limits of stability (LOS), and toes-up perturbations (4° at 50° per second) were tested while receiving and not receiving a combination of oral carbidopa (25 mg) and levodopa (250 mg) in the PSP group. Clinical assessment included Unified Parkinson's Disease Rating Scale, Performance-oriented assessments, and functional reach. Results: When compared with the PD and control groups, total LOS time (P<.001) and path sway (P<.001) were significantly prolonged in PSP. Total SOT showed significantly worse scores in PSP compared with PD and control groups (F2.57=29.6; P<.001). Univariate follow-up tests comparing PSP and PD showed differences in the following conditions: eyes open and visual sway (P=.003), eyes open and platform sway (P=.003), eyes closed and platform sway (P<.001), and eyes open and platform and visual sway (P<.001), Medium- and long-latency responses to perturbation were similar, but a larger number in the PSP group lacked short-latency responses (x2=11.3; P=.002). Levodopa administration did not significantly improve any aspect of posturography testing in PSP. In differentiating PSP from PD, LOS time and SOT condition of eyes open and platform and visual sway were nearly 100% sensitive and 100% specific (canonical correlation, 0.91). Conclusions: Computerized posturography testing reliably differentiated early PSP from early PD and age-matched controls. The PSP group demonstrated severely contracted limits of stability with probable deficits in motor programming. Results of SOT in PSP suggested a vestibular pattern and overreliance on visual cues, even when incorrect. The absence of short-latency responses (monosynaptic reflex arch) suggests an additional disturbance in the spinal cord or peripheral nervous system. |
| CC : | 002B17G |
| FD : | Ophtalmoplégie supranucléaire; Parkinson maladie; Stade précoce; Posturographie; Etude comparative; Homme |
| FG : | Oeil pathologie; Oculomotricité syndrome; Système nerveux pathologie; Système nerveux central pathologie; Tronc cérébral syndrome; Encéphale pathologie; Maladie dégénérative; Extrapyramidal syndrome |
| ED : | Supranuclear ophthalmoplegia; Parkinson disease; Early stage; Posturography; Comparative study; Human |
| EG : | Eye disease; Oculomotor syndrome; Nervous system diseases; Central nervous system disease; Brain stem syndrome; Cerebral disorder; Degenerative disease; Extrapyramidal syndrome |
| SD : | Oftalmoplejía supranuclear; Parkinson enfermedad; Estadio precoz; Posturografía; Estudio comparativo; Hombre |
| LO : | INIST-2048B.354000092734010090 |
| ID : | 00-0520598 |
Links to Exploration step
Pascal:00-0520598Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls</title><author><name sortKey="Ondo, William" sort="Ondo, William" uniqKey="Ondo W" first="William" last="Ondo">William Ondo</name><affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Baylor College of Medicine</s1><s2>Houston, Tex</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Warrior, Deborah" sort="Warrior, Deborah" uniqKey="Warrior D" first="Deborah" last="Warrior">Deborah Warrior</name><affiliation><inist:fA14 i1="02"><s1>School of Physical Therapy, Texas Women's University</s1><s2>Denton</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Overby, Averell" sort="Overby, Averell" uniqKey="Overby A" first="Averell" last="Overby">Averell Overby</name><affiliation><inist:fA14 i1="03"><s1>Department of Physical Therapy, Ohio University School of Medicine</s1><s2>Athens</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Calmes, Janine" sort="Calmes, Janine" uniqKey="Calmes J" first="Janine" last="Calmes">Janine Calmes</name><affiliation><inist:fA14 i1="02"><s1>School of Physical Therapy, Texas Women's University</s1><s2>Denton</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Hendersen, Nancy" sort="Hendersen, Nancy" uniqKey="Hendersen N" first="Nancy" last="Hendersen">Nancy Hendersen</name><affiliation><inist:fA14 i1="04"><s1>Physical Therapy Section, Madigan Army Medical Center</s1><s2>Tacoma, Wash</s2><s3>USA</s3><sZ>5 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Olson, Sharon" sort="Olson, Sharon" uniqKey="Olson S" first="Sharon" last="Olson">Sharon Olson</name><affiliation><inist:fA14 i1="02"><s1>School of Physical Therapy, Texas Women's University</s1><s2>Denton</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Baylor College of Medicine</s1><s2>Houston, Tex</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">00-0520598</idno><date when="2000">2000</date><idno type="stanalyst">PASCAL 00-0520598 INIST</idno><idno type="RBID">Pascal:00-0520598</idno><idno type="wicri:Area/PascalFrancis/Corpus">000156</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls</title><author><name sortKey="Ondo, William" sort="Ondo, William" uniqKey="Ondo W" first="William" last="Ondo">William Ondo</name><affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Baylor College of Medicine</s1><s2>Houston, Tex</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Warrior, Deborah" sort="Warrior, Deborah" uniqKey="Warrior D" first="Deborah" last="Warrior">Deborah Warrior</name><affiliation><inist:fA14 i1="02"><s1>School of Physical Therapy, Texas Women's University</s1><s2>Denton</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Overby, Averell" sort="Overby, Averell" uniqKey="Overby A" first="Averell" last="Overby">Averell Overby</name><affiliation><inist:fA14 i1="03"><s1>Department of Physical Therapy, Ohio University School of Medicine</s1><s2>Athens</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Calmes, Janine" sort="Calmes, Janine" uniqKey="Calmes J" first="Janine" last="Calmes">Janine Calmes</name><affiliation><inist:fA14 i1="02"><s1>School of Physical Therapy, Texas Women's University</s1><s2>Denton</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Hendersen, Nancy" sort="Hendersen, Nancy" uniqKey="Hendersen N" first="Nancy" last="Hendersen">Nancy Hendersen</name><affiliation><inist:fA14 i1="04"><s1>Physical Therapy Section, Madigan Army Medical Center</s1><s2>Tacoma, Wash</s2><s3>USA</s3><sZ>5 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Olson, Sharon" sort="Olson, Sharon" uniqKey="Olson S" first="Sharon" last="Olson">Sharon Olson</name><affiliation><inist:fA14 i1="02"><s1>School of Physical Therapy, Texas Women's University</s1><s2>Denton</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Baylor College of Medicine</s1><s2>Houston, Tex</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">Archives of neurology : (Chicago)</title><title level="j" type="abbreviated">Arch. neurol. : (Chic.)</title><idno type="ISSN">0003-9942</idno><imprint><date when="2000">2000</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Archives of neurology : (Chicago)</title><title level="j" type="abbreviated">Arch. neurol. : (Chic.)</title><idno type="ISSN">0003-9942</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Comparative study</term><term>Early stage</term><term>Human</term><term>Parkinson disease</term><term>Posturography</term><term>Supranuclear ophthalmoplegia</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Ophtalmoplégie supranucléaire</term><term>Parkinson maladie</term><term>Stade précoce</term><term>Posturographie</term><term>Etude comparative</term><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder that is frequently mistaken for Parkinson's disease (PD) in its early stages. Objective: To compare balance measures using computerized posturography in patients with early PSP and early PD. Methods: We performed computerized posturography (SMART Balance Master; NeuroCom International, Inc, Clackamas, Ore) in 20 patients with clinically diagnosed mild to moderate PSP (ambulatory) and compared results with those from 20 patients with PD of similar age and disease duration who were not receiving medications, and from 20 healthy age- and sex-matched controls. Sensory organization testing (SOT), limits of stability (LOS), and toes-up perturbations (4° at 50° per second) were tested while receiving and not receiving a combination of oral carbidopa (25 mg) and levodopa (250 mg) in the PSP group. Clinical assessment included Unified Parkinson's Disease Rating Scale, Performance-oriented assessments, and functional reach. Results: When compared with the PD and control groups, total LOS time (P<.001) and path sway (P<.001) were significantly prolonged in PSP. Total SOT showed significantly worse scores in PSP compared with PD and control groups (F<sub>2.57</sub>=29.6; P<.001). Univariate follow-up tests comparing PSP and PD showed differences in the following conditions: eyes open and visual sway (P=.003), eyes open and platform sway (P=.003), eyes closed and platform sway (P<.001), and eyes open and platform and visual sway (P<.001), Medium- and long-latency responses to perturbation were similar, but a larger number in the PSP group lacked short-latency responses (x<sup>2</sup>=11.3; P=.002). Levodopa administration did not significantly improve any aspect of posturography testing in PSP. In differentiating PSP from PD, LOS time and SOT condition of eyes open and platform and visual sway were nearly 100% sensitive and 100% specific (canonical correlation, 0.91). Conclusions: Computerized posturography testing reliably differentiated early PSP from early PD and age-matched controls. The PSP group demonstrated severely contracted limits of stability with probable deficits in motor programming. Results of SOT in PSP suggested a vestibular pattern and overreliance on visual cues, even when incorrect. The absence of short-latency responses (monosynaptic reflex arch) suggests an additional disturbance in the spinal cord or peripheral nervous system.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0003-9942</s0></fA01><fA02 i1="01"><s0>ARNEAS</s0></fA02><fA03 i2="1"><s0>Arch. neurol. : (Chic.)</s0></fA03><fA05><s2>57</s2></fA05><fA06><s2>10</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls</s1></fA08><fA11 i1="01" i2="1"><s1>ONDO (William)</s1></fA11><fA11 i1="02" i2="1"><s1>WARRIOR (Deborah)</s1></fA11><fA11 i1="03" i2="1"><s1>OVERBY (Averell)</s1></fA11><fA11 i1="04" i2="1"><s1>CALMES (Janine)</s1></fA11><fA11 i1="05" i2="1"><s1>HENDERSEN (Nancy)</s1></fA11><fA11 i1="06" i2="1"><s1>OLSON (Sharon)</s1></fA11><fA11 i1="07" i2="1"><s1>JANKOVIC (Joseph)</s1></fA11><fA14 i1="01"><s1>Department of Neurology, Baylor College of Medicine</s1><s2>Houston, Tex</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ></fA14><fA14 i1="02"><s1>School of Physical Therapy, Texas Women's University</s1><s2>Denton</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ></fA14><fA14 i1="03"><s1>Department of Physical Therapy, Ohio University School of Medicine</s1><s2>Athens</s2><s3>USA</s3><sZ>3 aut.</sZ></fA14><fA14 i1="04"><s1>Physical Therapy Section, Madigan Army Medical Center</s1><s2>Tacoma, Wash</s2><s3>USA</s3><sZ>5 aut.</sZ></fA14><fA20><s1>1464-1469</s1></fA20><fA21><s1>2000</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>2048B</s2><s5>354000092734010090</s5></fA43><fA44><s0>0000</s0><s1>© 2000 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>28 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>00-0520598</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Archives of neurology : (Chicago)</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder that is frequently mistaken for Parkinson's disease (PD) in its early stages. Objective: To compare balance measures using computerized posturography in patients with early PSP and early PD. Methods: We performed computerized posturography (SMART Balance Master; NeuroCom International, Inc, Clackamas, Ore) in 20 patients with clinically diagnosed mild to moderate PSP (ambulatory) and compared results with those from 20 patients with PD of similar age and disease duration who were not receiving medications, and from 20 healthy age- and sex-matched controls. Sensory organization testing (SOT), limits of stability (LOS), and toes-up perturbations (4° at 50° per second) were tested while receiving and not receiving a combination of oral carbidopa (25 mg) and levodopa (250 mg) in the PSP group. Clinical assessment included Unified Parkinson's Disease Rating Scale, Performance-oriented assessments, and functional reach. Results: When compared with the PD and control groups, total LOS time (P<.001) and path sway (P<.001) were significantly prolonged in PSP. Total SOT showed significantly worse scores in PSP compared with PD and control groups (F<sub>2.57</sub>=29.6; P<.001). Univariate follow-up tests comparing PSP and PD showed differences in the following conditions: eyes open and visual sway (P=.003), eyes open and platform sway (P=.003), eyes closed and platform sway (P<.001), and eyes open and platform and visual sway (P<.001), Medium- and long-latency responses to perturbation were similar, but a larger number in the PSP group lacked short-latency responses (x<sup>2</sup>=11.3; P=.002). Levodopa administration did not significantly improve any aspect of posturography testing in PSP. In differentiating PSP from PD, LOS time and SOT condition of eyes open and platform and visual sway were nearly 100% sensitive and 100% specific (canonical correlation, 0.91). Conclusions: Computerized posturography testing reliably differentiated early PSP from early PD and age-matched controls. The PSP group demonstrated severely contracted limits of stability with probable deficits in motor programming. Results of SOT in PSP suggested a vestibular pattern and overreliance on visual cues, even when incorrect. The absence of short-latency responses (monosynaptic reflex arch) suggests an additional disturbance in the spinal cord or peripheral nervous system.</s0></fC01><fC02 i1="01" i2="X"><s0>002B17G</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Ophtalmoplégie supranucléaire</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Supranuclear ophthalmoplegia</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Oftalmoplejía supranuclear</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Parkinson maladie</s0><s5>04</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Parkinson disease</s0><s5>04</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Parkinson enfermedad</s0><s5>04</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Stade précoce</s0><s5>16</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Early stage</s0><s5>16</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Estadio precoz</s0><s5>16</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Posturographie</s0><s5>17</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Posturography</s0><s5>17</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Posturografía</s0><s5>17</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Etude comparative</s0><s5>18</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Comparative study</s0><s5>18</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Estudio comparativo</s0><s5>18</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Homme</s0><s5>21</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Human</s0><s5>21</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Hombre</s0><s5>21</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Oeil pathologie</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Eye disease</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Ojo patología</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Oculomotricité syndrome</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Oculomotor syndrome</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Oculomotricidad síndrome</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Système nerveux pathologie</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>39</s5></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0><s5>40</s5></fC07><fC07 i1="05" i2="X" l="FRE"><s0>Tronc cérébral syndrome</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="ENG"><s0>Brain stem syndrome</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="SPA"><s0>Tallo encefalico sindrome</s0><s5>41</s5></fC07><fC07 i1="06" i2="X" l="FRE"><s0>Encéphale pathologie</s0><s5>42</s5></fC07><fC07 i1="06" i2="X" l="ENG"><s0>Cerebral disorder</s0><s5>42</s5></fC07><fC07 i1="06" i2="X" l="SPA"><s0>Encéfalo patología</s0><s5>42</s5></fC07><fC07 i1="07" i2="X" l="FRE"><s0>Maladie dégénérative</s0><s5>43</s5></fC07><fC07 i1="07" i2="X" l="ENG"><s0>Degenerative disease</s0><s5>43</s5></fC07><fC07 i1="07" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0><s5>43</s5></fC07><fC07 i1="08" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0><s5>48</s5></fC07><fC07 i1="08" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0><s5>48</s5></fC07><fC07 i1="08" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0><s5>48</s5></fC07><fN21><s1>346</s1></fN21></pA></standard><server><NO>PASCAL 00-0520598 INIST</NO><ET>Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls</ET><AU>ONDO (William); WARRIOR (Deborah); OVERBY (Averell); CALMES (Janine); HENDERSEN (Nancy); OLSON (Sharon); JANKOVIC (Joseph)</AU><AF>Department of Neurology, Baylor College of Medicine/Houston, Tex/Etats-Unis (1 aut., 7 aut.); School of Physical Therapy, Texas Women's University/Denton/Etats-Unis (2 aut., 4 aut., 6 aut.); Department of Physical Therapy, Ohio University School of Medicine/Athens/Etats-Unis (3 aut.); Physical Therapy Section, Madigan Army Medical Center/Tacoma, Wash/Etats-Unis (5 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>Archives of neurology : (Chicago); ISSN 0003-9942; Coden ARNEAS; Etats-Unis; Da. 2000; Vol. 57; No. 10; Pp. 1464-1469; Bibl. 28 ref.</SO><LA>Anglais</LA><EA>Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder that is frequently mistaken for Parkinson's disease (PD) in its early stages. Objective: To compare balance measures using computerized posturography in patients with early PSP and early PD. Methods: We performed computerized posturography (SMART Balance Master; NeuroCom International, Inc, Clackamas, Ore) in 20 patients with clinically diagnosed mild to moderate PSP (ambulatory) and compared results with those from 20 patients with PD of similar age and disease duration who were not receiving medications, and from 20 healthy age- and sex-matched controls. Sensory organization testing (SOT), limits of stability (LOS), and toes-up perturbations (4° at 50° per second) were tested while receiving and not receiving a combination of oral carbidopa (25 mg) and levodopa (250 mg) in the PSP group. Clinical assessment included Unified Parkinson's Disease Rating Scale, Performance-oriented assessments, and functional reach. Results: When compared with the PD and control groups, total LOS time (P<.001) and path sway (P<.001) were significantly prolonged in PSP. Total SOT showed significantly worse scores in PSP compared with PD and control groups (F<sub>2.57</sub>=29.6; P<.001). Univariate follow-up tests comparing PSP and PD showed differences in the following conditions: eyes open and visual sway (P=.003), eyes open and platform sway (P=.003), eyes closed and platform sway (P<.001), and eyes open and platform and visual sway (P<.001), Medium- and long-latency responses to perturbation were similar, but a larger number in the PSP group lacked short-latency responses (x<sup>2</sup>=11.3; P=.002). Levodopa administration did not significantly improve any aspect of posturography testing in PSP. In differentiating PSP from PD, LOS time and SOT condition of eyes open and platform and visual sway were nearly 100% sensitive and 100% specific (canonical correlation, 0.91). Conclusions: Computerized posturography testing reliably differentiated early PSP from early PD and age-matched controls. The PSP group demonstrated severely contracted limits of stability with probable deficits in motor programming. Results of SOT in PSP suggested a vestibular pattern and overreliance on visual cues, even when incorrect. The absence of short-latency responses (monosynaptic reflex arch) suggests an additional disturbance in the spinal cord or peripheral nervous system.</EA><CC>002B17G</CC><FD>Ophtalmoplégie supranucléaire; Parkinson maladie; Stade précoce; Posturographie; Etude comparative; Homme</FD><FG>Oeil pathologie; Oculomotricité syndrome; Système nerveux pathologie; Système nerveux central pathologie; Tronc cérébral syndrome; Encéphale pathologie; Maladie dégénérative; Extrapyramidal syndrome</FG><ED>Supranuclear ophthalmoplegia; Parkinson disease; Early stage; Posturography; Comparative study; Human</ED><EG>Eye disease; Oculomotor syndrome; Nervous system diseases; Central nervous system disease; Brain stem syndrome; Cerebral disorder; Degenerative disease; Extrapyramidal syndrome</EG><SD>Oftalmoplejía supranuclear; Parkinson enfermedad; Estadio precoz; Posturografía; Estudio comparativo; Hombre</SD><LO>INIST-2048B.354000092734010090</LO><ID>00-0520598</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/JankovicV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000156 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000156 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= JankovicV1
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:00-0520598
|texte= Computerized posturography analysis of Progressive supranuclear palsy: A case-control comparison with Parkinson's Disease and healthy controls
}}
| This area was generated with Dilib version V0.6.19. |  |