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Systematic genetic analysis of the PITX3 gene in patients with Parkinson disease.

Identifieur interne : 000325 ( Ncbi/Curation ); précédent : 000324; suivant : 000326

Systematic genetic analysis of the PITX3 gene in patients with Parkinson disease.

Auteurs : Yi Guo [République populaire de Chine] ; Wei Le ; Joseph Jankovic [États-Unis] ; Hua Yang ; Hong Xu ; Wen Xie ; Zhi Song ; Hao Deng

Source :

RBID : pubmed:21469209

English descriptors

Abstract

Paired-like homodomain transcription factor 3 has been found to be important for the differentiation and survival of midbrain dopaminergic neurons.

DOI: 10.1002/mds.23693
PubMed: 21469209

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pubmed:21469209

Le document en format XML

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<nlm:affiliation>Center for Experimental Medicine and Department of Neurology, the Third Xiangya Hospital, and Department of Physiology, Xiangya Medical School, Central South University, Changsha, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Center for Experimental Medicine and Department of Neurology, the Third Xiangya Hospital, and Department of Physiology, Xiangya Medical School, Central South University, Changsha</wicri:regionArea>
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<country>États-Unis</country>
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<name sortKey="Yang, Hua Rong" sort="Yang, Hua Rong" uniqKey="Yang H" first="Hua" last="Yang">Hua Yang</name>
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<name sortKey="Xu, Hong Bo" sort="Xu, Hong Bo" uniqKey="Xu H" first="Hong" last="Xu">Hong Xu</name>
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<name sortKey="Xie, Wen Jie" sort="Xie, Wen Jie" uniqKey="Xie W" first="Wen" last="Xie">Wen Xie</name>
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<name sortKey="Song, Zhi" sort="Song, Zhi" uniqKey="Song Z" first="Zhi" last="Song">Zhi Song</name>
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<nlm:affiliation>Center for Experimental Medicine and Department of Neurology, the Third Xiangya Hospital, and Department of Physiology, Xiangya Medical School, Central South University, Changsha, China.</nlm:affiliation>
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<name sortKey="Yang, Hua Rong" sort="Yang, Hua Rong" uniqKey="Yang H" first="Hua" last="Yang">Hua Yang</name>
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<name sortKey="Xu, Hong Bo" sort="Xu, Hong Bo" uniqKey="Xu H" first="Hong" last="Xu">Hong Xu</name>
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<name sortKey="Xie, Wen Jie" sort="Xie, Wen Jie" uniqKey="Xie W" first="Wen" last="Xie">Wen Xie</name>
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<name sortKey="Song, Zhi" sort="Song, Zhi" uniqKey="Song Z" first="Zhi" last="Song">Zhi Song</name>
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<name sortKey="Deng, Hao" sort="Deng, Hao" uniqKey="Deng H" first="Hao" last="Deng">Hao Deng</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Female</term>
<term>Gene Frequency</term>
<term>Genetic Association Studies</term>
<term>Genetic Predisposition to Disease (genetics)</term>
<term>Genotype</term>
<term>Homeodomain Proteins (genetics)</term>
<term>Humans</term>
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<term>Parkinson Disease (genetics)</term>
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<term>Homeodomain Proteins</term>
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<term>Genetic Predisposition to Disease</term>
<term>Parkinson Disease</term>
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<term>Case-Control Studies</term>
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<div type="abstract" xml:lang="en">Paired-like homodomain transcription factor 3 has been found to be important for the differentiation and survival of midbrain dopaminergic neurons.</div>
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