Serum cholesterol and the progression of Parkinson's disease: results from DATATOP.
Identifieur interne : 000340 ( Ncbi/Checkpoint ); précédent : 000339; suivant : 000341Serum cholesterol and the progression of Parkinson's disease: results from DATATOP.
Auteurs : Xuemei Huang [États-Unis] ; Peggy Auinger ; Shirley Eberly ; David Oakes ; Michael Schwarzschild ; Alberto Ascherio ; Richard Mailman ; Honglei ChenSource :
- PloS one ; 2011.
English descriptors
- KwdEn :
- Antioxidants (therapeutic use), Cholesterol (blood), Disease Progression, Endpoint Determination, Female, Humans, Male, Middle Aged, Parkinson Disease (blood), Parkinson Disease (drug therapy), Parkinson Disease (pathology), Proportional Hazards Models, Randomized Controlled Trials as Topic, Selegiline (therapeutic use), Tocopherols (therapeutic use).
- MESH :
- chemical , blood : Cholesterol.
- chemical , therapeutic use : Antioxidants, Selegiline, Tocopherols.
- blood : Parkinson Disease.
- drug therapy : Parkinson Disease.
- pathology : Parkinson Disease.
- Disease Progression, Endpoint Determination, Female, Humans, Male, Middle Aged, Proportional Hazards Models, Randomized Controlled Trials as Topic.
Abstract
Recent studies have suggested that higher serum cholesterol may be associated with lower occurrence of Parkinson's disease (PD). This study is to test the hypothesis that higher serum cholesterol correlates with slower PD progression.
DOI: 10.1371/journal.pone.0022854
PubMed: 21853051
Affiliations:
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pubmed:21853051Le document en format XML
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<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Pennsylvania State University-Milton Hershey Medical Center, Hershey, Pennsylvania, United States of America. Xuemei@psu.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Pennsylvania State University-Milton Hershey Medical Center, Hershey, Pennsylvania</wicri:regionArea>
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<author><name sortKey="Auinger, Peggy" sort="Auinger, Peggy" uniqKey="Auinger P" first="Peggy" last="Auinger">Peggy Auinger</name>
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<author><name sortKey="Eberly, Shirley" sort="Eberly, Shirley" uniqKey="Eberly S" first="Shirley" last="Eberly">Shirley Eberly</name>
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<author><name sortKey="Oakes, David" sort="Oakes, David" uniqKey="Oakes D" first="David" last="Oakes">David Oakes</name>
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<author><name sortKey="Schwarzschild, Michael" sort="Schwarzschild, Michael" uniqKey="Schwarzschild M" first="Michael" last="Schwarzschild">Michael Schwarzschild</name>
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<author><name sortKey="Ascherio, Alberto" sort="Ascherio, Alberto" uniqKey="Ascherio A" first="Alberto" last="Ascherio">Alberto Ascherio</name>
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<author><name sortKey="Mailman, Richard" sort="Mailman, Richard" uniqKey="Mailman R" first="Richard" last="Mailman">Richard Mailman</name>
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<author><name sortKey="Chen, Honglei" sort="Chen, Honglei" uniqKey="Chen H" first="Honglei" last="Chen">Honglei Chen</name>
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<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Pennsylvania State University-Milton Hershey Medical Center, Hershey, Pennsylvania, United States of America. Xuemei@psu.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Pennsylvania State University-Milton Hershey Medical Center, Hershey, Pennsylvania</wicri:regionArea>
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<author><name sortKey="Auinger, Peggy" sort="Auinger, Peggy" uniqKey="Auinger P" first="Peggy" last="Auinger">Peggy Auinger</name>
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<author><name sortKey="Eberly, Shirley" sort="Eberly, Shirley" uniqKey="Eberly S" first="Shirley" last="Eberly">Shirley Eberly</name>
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<author><name sortKey="Oakes, David" sort="Oakes, David" uniqKey="Oakes D" first="David" last="Oakes">David Oakes</name>
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<author><name sortKey="Schwarzschild, Michael" sort="Schwarzschild, Michael" uniqKey="Schwarzschild M" first="Michael" last="Schwarzschild">Michael Schwarzschild</name>
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<author><name sortKey="Ascherio, Alberto" sort="Ascherio, Alberto" uniqKey="Ascherio A" first="Alberto" last="Ascherio">Alberto Ascherio</name>
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<author><name sortKey="Mailman, Richard" sort="Mailman, Richard" uniqKey="Mailman R" first="Richard" last="Mailman">Richard Mailman</name>
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<author><name sortKey="Chen, Honglei" sort="Chen, Honglei" uniqKey="Chen H" first="Honglei" last="Chen">Honglei Chen</name>
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<series><title level="j">PloS one</title>
<idno type="e-ISSN">1932-6203</idno>
<imprint><date when="2011" type="published">2011</date>
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<term>Disease Progression</term>
<term>Endpoint Determination</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (blood)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (pathology)</term>
<term>Proportional Hazards Models</term>
<term>Randomized Controlled Trials as Topic</term>
<term>Selegiline (therapeutic use)</term>
<term>Tocopherols (therapeutic use)</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Cholesterol</term>
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<term>Selegiline</term>
<term>Tocopherols</term>
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<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
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<keywords scheme="MESH" xml:lang="en"><term>Disease Progression</term>
<term>Endpoint Determination</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Proportional Hazards Models</term>
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<front><div type="abstract" xml:lang="en">Recent studies have suggested that higher serum cholesterol may be associated with lower occurrence of Parkinson's disease (PD). This study is to test the hypothesis that higher serum cholesterol correlates with slower PD progression.</div>
</front>
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<region><li>Pennsylvanie</li>
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<tree><noCountry><name sortKey="Ascherio, Alberto" sort="Ascherio, Alberto" uniqKey="Ascherio A" first="Alberto" last="Ascherio">Alberto Ascherio</name>
<name sortKey="Auinger, Peggy" sort="Auinger, Peggy" uniqKey="Auinger P" first="Peggy" last="Auinger">Peggy Auinger</name>
<name sortKey="Chen, Honglei" sort="Chen, Honglei" uniqKey="Chen H" first="Honglei" last="Chen">Honglei Chen</name>
<name sortKey="Eberly, Shirley" sort="Eberly, Shirley" uniqKey="Eberly S" first="Shirley" last="Eberly">Shirley Eberly</name>
<name sortKey="Mailman, Richard" sort="Mailman, Richard" uniqKey="Mailman R" first="Richard" last="Mailman">Richard Mailman</name>
<name sortKey="Oakes, David" sort="Oakes, David" uniqKey="Oakes D" first="David" last="Oakes">David Oakes</name>
<name sortKey="Schwarzschild, Michael" sort="Schwarzschild, Michael" uniqKey="Schwarzschild M" first="Michael" last="Schwarzschild">Michael Schwarzschild</name>
</noCountry>
<country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Huang, Xuemei" sort="Huang, Xuemei" uniqKey="Huang X" first="Xuemei" last="Huang">Xuemei Huang</name>
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