H2N2V1, PubMed, Curation, bibRecord, 000086

Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in Eastern China.

Identifieur interne : 000086 ( PubMed/Curation ); précédent : 000085; suivant : 000087

Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in Eastern China.

Source :

Scientific reports [ 2045-2322 ] ; 2014.

RBID : pubmed:25533850

Descripteurs français

KwdFr :
- Animaux, Anticorps antiviraux (immunologie), Anticorps antiviraux (sang), Canards (immunologie), Canards (sang), Canards (virologie), Chine, Grippe chez les oiseaux (immunologie), Grippe chez les oiseaux (sang), Grippe chez les oiseaux (virologie), Humains, Maladies de la volaille (immunologie), Maladies de la volaille (sang), Maladies de la volaille (virologie), Sous-type H2N2 du virus de la grippe A (génétique), Sous-type H2N2 du virus de la grippe A (immunologie), Sous-type H2N2 du virus de la grippe A (isolement et purification).
MESH :
- génétique : Sous-type H2N2 du virus de la grippe A.
- immunologie : Anticorps antiviraux, Canards, Grippe chez les oiseaux, Maladies de la volaille, Sous-type H2N2 du virus de la grippe A.
- isolement et purification : Sous-type H2N2 du virus de la grippe A.
- sang : Anticorps antiviraux, Canards, Grippe chez les oiseaux, Maladies de la volaille.
- virologie : Canards, Grippe chez les oiseaux, Maladies de la volaille.
- Animaux, Chine, Humains.
Wicri :
- geographic : République populaire de Chine.

English descriptors

KwdEn :
- Animals, Antibodies, Viral (blood), Antibodies, Viral (immunology), China, Ducks (blood), Ducks (immunology), Ducks (virology), Humans, Influenza A Virus, H2N2 Subtype (genetics), Influenza A Virus, H2N2 Subtype (immunology), Influenza A Virus, H2N2 Subtype (isolation & purification), Influenza in Birds (blood), Influenza in Birds (immunology), Influenza in Birds (virology), Poultry Diseases (blood), Poultry Diseases (immunology), Poultry Diseases (virology).
MESH :
- chemical , blood : Antibodies, Viral.
- chemical , immunology : Antibodies, Viral.
- geographic : China.
- blood : Ducks, Influenza in Birds, Poultry Diseases.
- genetics : Influenza A Virus, H2N2 Subtype.
- immunology : Ducks, Influenza A Virus, H2N2 Subtype, Influenza in Birds, Poultry Diseases.
- isolation & purification : Influenza A Virus, H2N2 Subtype.
- virology : Ducks, Influenza in Birds, Poultry Diseases.
- Animals, Humans.

Abstract

While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infection. We report the isolation of a novel influenza A virus (H2N2) cultured in 2013 from a healthy domestic duck at a live poultry market in Wuxi City, China. Sequence data revealed that the novel H2N2 virus was similar to Eurasian avian lineage avian influenza viruses, the virus had been circulating for ≥ two years among poultry, had an increase in α2,6 binding affinity, and was not highly pathogenic. Approximately 9% of 100 healthy chickens sampled from the same area had elevated antibodies against the H2 antigen. Fortunately, there was sparse serological evidence that the virus was infecting poultry workers or had adapted to infect other mammals. These findings suggest that a novel H2N2 virus has been circulating among domestic poultry in Wuxi City, China and has some has increased human receptor affinity. It seems wise to conduct better surveillance for novel influenza viruses at Chinese live bird markets.

DOI: 10.1038/srep07588
PubMed: 25533850

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<author><name sortKey="Sang, Xiao Yu" sort="Sang, Xiao Yu" uniqKey="Sang X" first="Xiao-Yu" last="Sang">Xiao-Yu Sang</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in Eastern China.</title>
<author><name sortKey="Ma, Mai Juan" sort="Ma, Mai Juan" uniqKey="Ma M" first="Mai-Juan" last="Ma">Mai-Juan Ma</name>
<affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071</wicri:regionArea>
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<author><name sortKey="Yang, Xiao Xian" sort="Yang, Xiao Xian" uniqKey="Yang X" first="Xiao-Xian" last="Yang">Xiao-Xian Yang</name>
<affiliation wicri:level="1"><nlm:affiliation>1] State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China [2] School of Public Health, Central South University, Changsha, Hunan, 410000 P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>1] State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China [2] School of Public Health, Central South University, Changsha, Hunan</wicri:regionArea>
</affiliation>
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<author><name sortKey="Qian, Yan Hua" sort="Qian, Yan Hua" uniqKey="Qian Y" first="Yan-Hua" last="Qian">Yan-Hua Qian</name>
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<wicri:regionArea>Wuxi Center for Disease Control and Prevention, Wuxi, 214023</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhao, Si Yan" sort="Zhao, Si Yan" uniqKey="Zhao S" first="Si-Yan" last="Zhao">Si-Yan Zhao</name>
<affiliation wicri:level="1"><nlm:affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122</wicri:regionArea>
</affiliation>
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<author><name sortKey="Hua, Sha" sort="Hua, Sha" uniqKey="Hua S" first="Sha" last="Hua">Sha Hua</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, P. R. China [2] University of Chinese Academy of Sciences, Beijing, 100049, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>1] Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, P. R. China [2] University of Chinese Academy of Sciences, Beijing, 100049</wicri:regionArea>
</affiliation>
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<author><name sortKey="Wang, Tie Cheng" sort="Wang, Tie Cheng" uniqKey="Wang T" first="Tie-Cheng" last="Wang">Tie-Cheng Wang</name>
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<author><name sortKey="Chen, Shan Hui" sort="Chen, Shan Hui" uniqKey="Chen S" first="Shan-Hui" last="Chen">Shan-Hui Chen</name>
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<author><name sortKey="Ma, Guang Yuan" sort="Ma, Guang Yuan" uniqKey="Ma G" first="Guang-Yuan" last="Ma">Guang-Yuan Ma</name>
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<author><name sortKey="Sang, Xiao Yu" sort="Sang, Xiao Yu" uniqKey="Sang X" first="Xiao-Yu" last="Sang">Xiao-Yu Sang</name>
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<author><name sortKey="Liu, Lin Na" sort="Liu, Lin Na" uniqKey="Liu L" first="Lin-Na" last="Liu">Lin-Na Liu</name>
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<author><name sortKey="Wu, Ai Ping" sort="Wu, Ai Ping" uniqKey="Wu A" first="Ai-Ping" last="Wu">Ai-Ping Wu</name>
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<author><name sortKey="Jiang, Tai Jiao" sort="Jiang, Tai Jiao" uniqKey="Jiang T" first="Tai-Jiao" last="Jiang">Tai-Jiao Jiang</name>
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<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
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<author><name sortKey="Gao, Yu Wei" sort="Gao, Yu Wei" uniqKey="Gao Y" first="Yu-Wei" last="Gao">Yu-Wei Gao</name>
<affiliation wicri:level="1"><nlm:affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122</wicri:regionArea>
</affiliation>
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<author><name sortKey="Gray, Gregory C" sort="Gray, Gregory C" uniqKey="Gray G" first="Gregory C" last="Gray">Gregory C. Gray</name>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Duke Infectious Disease &Duke Health Institute, Duke University Medical Center, Durham, NC, 27710</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhao, Teng" sort="Zhao, Teng" uniqKey="Zhao T" first="Teng" last="Zhao">Teng Zhao</name>
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<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ling, Xia" sort="Ling, Xia" uniqKey="Ling X" first="Xia" last="Ling">Xia Ling</name>
<affiliation wicri:level="1"><nlm:affiliation>Wuxi Center for Disease Control and Prevention, Wuxi, 214023, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
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<author><name sortKey="Wang, Jing Lin" sort="Wang, Jing Lin" uniqKey="Wang J" first="Jing-Lin" last="Wang">Jing-Lin Wang</name>
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<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
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<author><name sortKey="Lu, Bing" sort="Lu, Bing" uniqKey="Lu B" first="Bing" last="Lu">Bing Lu</name>
<affiliation wicri:level="1"><nlm:affiliation>Wuxi Center for Disease Control and Prevention, Wuxi, 214023, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Wuxi Center for Disease Control and Prevention, Wuxi, 214023</wicri:regionArea>
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<author><name sortKey="Qian, Jun" sort="Qian, Jun" uniqKey="Qian J" first="Jun" last="Qian">Jun Qian</name>
<affiliation wicri:level="1"><nlm:affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
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<author><name sortKey="Cao, Wu Chun" sort="Cao, Wu Chun" uniqKey="Cao W" first="Wu-Chun" last="Cao">Wu-Chun Cao</name>
<affiliation wicri:level="1"><nlm:affiliation>1] State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China [2] School of Public Health, Central South University, Changsha, Hunan, 410000 P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>1] State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China [2] School of Public Health, Central South University, Changsha, Hunan</wicri:regionArea>
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<series><title level="j">Scientific reports</title>
<idno type="eISSN">2045-2322</idno>
<imprint><date when="2014" type="published">2014</date>
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<term>Antibodies, Viral (blood)</term>
<term>Antibodies, Viral (immunology)</term>
<term>China</term>
<term>Ducks (blood)</term>
<term>Ducks (immunology)</term>
<term>Ducks (virology)</term>
<term>Humans</term>
<term>Influenza A Virus, H2N2 Subtype (genetics)</term>
<term>Influenza A Virus, H2N2 Subtype (immunology)</term>
<term>Influenza A Virus, H2N2 Subtype (isolation & purification)</term>
<term>Influenza in Birds (blood)</term>
<term>Influenza in Birds (immunology)</term>
<term>Influenza in Birds (virology)</term>
<term>Poultry Diseases (blood)</term>
<term>Poultry Diseases (immunology)</term>
<term>Poultry Diseases (virology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Anticorps antiviraux (immunologie)</term>
<term>Anticorps antiviraux (sang)</term>
<term>Canards (immunologie)</term>
<term>Canards (sang)</term>
<term>Canards (virologie)</term>
<term>Chine</term>
<term>Grippe chez les oiseaux (immunologie)</term>
<term>Grippe chez les oiseaux (sang)</term>
<term>Grippe chez les oiseaux (virologie)</term>
<term>Humains</term>
<term>Maladies de la volaille (immunologie)</term>
<term>Maladies de la volaille (sang)</term>
<term>Maladies de la volaille (virologie)</term>
<term>Sous-type H2N2 du virus de la grippe A (génétique)</term>
<term>Sous-type H2N2 du virus de la grippe A (immunologie)</term>
<term>Sous-type H2N2 du virus de la grippe A (isolement et purification)</term>
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</keywords>
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</keywords>
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<term>Influenza in Birds</term>
<term>Poultry Diseases</term>
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<term>Canards</term>
<term>Grippe chez les oiseaux</term>
<term>Maladies de la volaille</term>
<term>Sous-type H2N2 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Ducks</term>
<term>Influenza A Virus, H2N2 Subtype</term>
<term>Influenza in Birds</term>
<term>Poultry Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H2N2 Subtype</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H2N2 du virus de la grippe A</term>
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<term>Canards</term>
<term>Grippe chez les oiseaux</term>
<term>Maladies de la volaille</term>
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<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Canards</term>
<term>Grippe chez les oiseaux</term>
<term>Maladies de la volaille</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Ducks</term>
<term>Influenza in Birds</term>
<term>Poultry Diseases</term>
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<term>Humans</term>
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<term>Chine</term>
<term>Humains</term>
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<front><div type="abstract" xml:lang="en">While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infection. We report the isolation of a novel influenza A virus (H2N2) cultured in 2013 from a healthy domestic duck at a live poultry market in Wuxi City, China. Sequence data revealed that the novel H2N2 virus was similar to Eurasian avian lineage avian influenza viruses, the virus had been circulating for ≥ two years among poultry, had an increase in α2,6 binding affinity, and was not highly pathogenic. Approximately 9% of 100 healthy chickens sampled from the same area had elevated antibodies against the H2 antigen. Fortunately, there was sparse serological evidence that the virus was infecting poultry workers or had adapted to infect other mammals. These findings suggest that a novel H2N2 virus has been circulating among domestic poultry in Wuxi City, China and has some has increased human receptor affinity. It seems wise to conduct better surveillance for novel influenza viruses at Chinese live bird markets. </div>
</front>
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<DateCompleted><Year>2015</Year>
<Month>10</Month>
<Day>02</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2045-2322</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>4</Volume>
<PubDate><Year>2014</Year>
<Month>Dec</Month>
<Day>23</Day>
</PubDate>
</JournalIssue>
<Title>Scientific reports</Title>
<ISOAbbreviation>Sci Rep</ISOAbbreviation>
</Journal>
<ArticleTitle>Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in Eastern China.</ArticleTitle>
<Pagination><MedlinePgn>7588</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/srep07588</ELocationID>
<Abstract><AbstractText>While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infection. We report the isolation of a novel influenza A virus (H2N2) cultured in 2013 from a healthy domestic duck at a live poultry market in Wuxi City, China. Sequence data revealed that the novel H2N2 virus was similar to Eurasian avian lineage avian influenza viruses, the virus had been circulating for ≥ two years among poultry, had an increase in α2,6 binding affinity, and was not highly pathogenic. Approximately 9% of 100 healthy chickens sampled from the same area had elevated antibodies against the H2 antigen. Fortunately, there was sparse serological evidence that the virus was infecting poultry workers or had adapted to infect other mammals. These findings suggest that a novel H2N2 virus has been circulating among domestic poultry in Wuxi City, China and has some has increased human receptor affinity. It seems wise to conduct better surveillance for novel influenza viruses at Chinese live bird markets. </AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ma</LastName>
<ForeName>Mai-Juan</ForeName>
<Initials>MJ</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yang</LastName>
<ForeName>Xiao-Xian</ForeName>
<Initials>XX</Initials>
<AffiliationInfo><Affiliation>1] State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China [2] School of Public Health, Central South University, Changsha, Hunan, 410000 P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Qian</LastName>
<ForeName>Yan-Hua</ForeName>
<Initials>YH</Initials>
<AffiliationInfo><Affiliation>Wuxi Center for Disease Control and Prevention, Wuxi, 214023, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhao</LastName>
<ForeName>Si-Yan</ForeName>
<Initials>SY</Initials>
<AffiliationInfo><Affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hua</LastName>
<ForeName>Sha</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>1] Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, P. R. China [2] University of Chinese Academy of Sciences, Beijing, 100049, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Tie-Cheng</ForeName>
<Initials>TC</Initials>
<AffiliationInfo><Affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Shan-Hui</ForeName>
<Initials>SH</Initials>
<AffiliationInfo><Affiliation>Wuxi Center for Disease Control and Prevention, Wuxi, 214023, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ma</LastName>
<ForeName>Guang-Yuan</ForeName>
<Initials>GY</Initials>
<AffiliationInfo><Affiliation>Wuxi Center for Disease Control and Prevention, Wuxi, 214023, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sang</LastName>
<ForeName>Xiao-Yu</ForeName>
<Initials>XY</Initials>
<AffiliationInfo><Affiliation>Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, 150001, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Lin-Na</ForeName>
<Initials>LN</Initials>
<AffiliationInfo><Affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wu</LastName>
<ForeName>Ai-Ping</ForeName>
<Initials>AP</Initials>
<AffiliationInfo><Affiliation>Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jiang</LastName>
<ForeName>Tai-Jiao</ForeName>
<Initials>TJ</Initials>
<AffiliationInfo><Affiliation>Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gao</LastName>
<ForeName>Yu-Wei</ForeName>
<Initials>YW</Initials>
<AffiliationInfo><Affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gray</LastName>
<ForeName>Gregory C</ForeName>
<Initials>GC</Initials>
<AffiliationInfo><Affiliation>Duke Infectious Disease &Duke Health Institute, Duke University Medical Center, Durham, NC, 27710, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhao</LastName>
<ForeName>Teng</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ling</LastName>
<ForeName>Xia</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>Wuxi Center for Disease Control and Prevention, Wuxi, 214023, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Jing-Lin</ForeName>
<Initials>JL</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lu</LastName>
<ForeName>Bing</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Wuxi Center for Disease Control and Prevention, Wuxi, 214023, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Qian</LastName>
<ForeName>Jun</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, 130122, P. R. China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cao</LastName>
<ForeName>Wu-Chun</ForeName>
<Initials>WC</Initials>
<AffiliationInfo><Affiliation>1] State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, P. R. China [2] School of Public Health, Central South University, Changsha, Hunan, 410000 P. R. China.</Affiliation>
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<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<Month>12</Month>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N" Type="Geographic">China</DescriptorName>
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</MeshHeading>
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<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D005585" MajorTopicYN="Y">Influenza in Birds</DescriptorName>
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	Serveur d'exploration H2N2
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Serveur d'exploration H2N2

Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in Eastern China.

Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in Eastern China.

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