Prenatal influenza exposure and cardiovascular events in adulthood
Identifieur interne : 000985 ( Pmc/Curation ); précédent : 000984; suivant : 000986Prenatal influenza exposure and cardiovascular events in adulthood
Auteurs : Noelle M. Cocoros [États-Unis] ; Timothy L. Lash [États-Unis] ; Al Ozonoff [États-Unis] ; Mette N Rgaard [Danemark] ; Alfred Demaria [États-Unis] ; Viggo Andreasen [Danemark] ; Henrik Toft S Rensen [Danemark]Source :
- Influenza and Other Respiratory Viruses [ 1750-2640 ] ; 2013.
Abstract
This study examined the association between prenatal exposure to pandemic influenza and cardiovascular events in adulthood.
Using Danish surveillance data to identify months when influenza activity was highest during three previous pandemics (1918, 1957, and 1968), persons were defined as exposed/unexposed based on whether they were
Information from Danish national registries on all persons with a Civil Personal Registry number and birthdates in 1915 through 1922, 1954 through 1960, and 1966 through 1972 was collected.
Crude incidence rate ratios (IRRs) were calculated per pandemic. Generalized linear models were fit to estimate IRRs adjusted for sex.
For acute MI, sex-adjusted IRRs for persons
There was generally no evidence of an association between prenatal influenza exposure and acute MI or stroke in adulthood. However, survivor bias and left truncation of outcomes for the 1918 pandemic are possible, and the current young ages of persons included in the analyses for the 1957 and 1968 pandemics may warrant later re-evaluation.
Url:
DOI: 10.1111/irv.12202
PubMed: 24373293
PubMed Central: 4177801
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000985
Links to Exploration step
PMC:4177801Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Prenatal influenza exposure and cardiovascular events in adulthood</title>
<author><name sortKey="Cocoros, Noelle M" sort="Cocoros, Noelle M" uniqKey="Cocoros N" first="Noelle M" last="Cocoros">Noelle M. Cocoros</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Massachusetts Department of Public Health, Bureau of Infectious Disease</institution>
<addr-line>Jamaica Plain, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Jamaica Plain, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lash, Timothy L" sort="Lash, Timothy L" uniqKey="Lash T" first="Timothy L" last="Lash">Timothy L. Lash</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Epidemiology, Rollins School of Public Health, Emory University</institution>
<addr-line>Atlanta, GA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Atlanta, GA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ozonoff, Al" sort="Ozonoff, Al" uniqKey="Ozonoff A" first="Al" last="Ozonoff">Al Ozonoff</name>
<affiliation wicri:level="1"><nlm:aff id="au3"><institution>Center for Patient Safety and Quality Research, Program for Patient Safety and Quality, Boston Children's Hospital</institution>
<addr-line>Boston, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Boston, MA</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="au4"><institution>Department of Pediatrics, Harvard Medical School</institution>
<addr-line>Boston, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="N Rgaard, Mette" sort="N Rgaard, Mette" uniqKey="N Rgaard M" first="Mette" last="N Rgaard">Mette N Rgaard</name>
<affiliation wicri:level="1"><nlm:aff id="au5"><institution>Department of Clinical Epidemiology, Aarhus University Hospital</institution>
<addr-line>Aarhus, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Aarhus</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Demaria, Alfred" sort="Demaria, Alfred" uniqKey="Demaria A" first="Alfred" last="Demaria">Alfred Demaria</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Massachusetts Department of Public Health, Bureau of Infectious Disease</institution>
<addr-line>Jamaica Plain, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Jamaica Plain, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andreasen, Viggo" sort="Andreasen, Viggo" uniqKey="Andreasen V" first="Viggo" last="Andreasen">Viggo Andreasen</name>
<affiliation wicri:level="1"><nlm:aff id="au6"><institution>Department of Science, Systems, and Models, Roskilde University</institution>
<addr-line>Roskilde, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Roskilde</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="S Rensen, Henrik Toft" sort="S Rensen, Henrik Toft" uniqKey="S Rensen H" first="Henrik Toft" last="S Rensen">Henrik Toft S Rensen</name>
<affiliation wicri:level="1"><nlm:aff id="au5"><institution>Department of Clinical Epidemiology, Aarhus University Hospital</institution>
<addr-line>Aarhus, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Aarhus</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24373293</idno>
<idno type="pmc">4177801</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177801</idno>
<idno type="RBID">PMC:4177801</idno>
<idno type="doi">10.1111/irv.12202</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">000985</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000985</idno>
<idno type="wicri:Area/Pmc/Curation">000985</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000985</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Prenatal influenza exposure and cardiovascular events in adulthood</title>
<author><name sortKey="Cocoros, Noelle M" sort="Cocoros, Noelle M" uniqKey="Cocoros N" first="Noelle M" last="Cocoros">Noelle M. Cocoros</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Massachusetts Department of Public Health, Bureau of Infectious Disease</institution>
<addr-line>Jamaica Plain, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Jamaica Plain, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lash, Timothy L" sort="Lash, Timothy L" uniqKey="Lash T" first="Timothy L" last="Lash">Timothy L. Lash</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>Department of Epidemiology, Rollins School of Public Health, Emory University</institution>
<addr-line>Atlanta, GA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Atlanta, GA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ozonoff, Al" sort="Ozonoff, Al" uniqKey="Ozonoff A" first="Al" last="Ozonoff">Al Ozonoff</name>
<affiliation wicri:level="1"><nlm:aff id="au3"><institution>Center for Patient Safety and Quality Research, Program for Patient Safety and Quality, Boston Children's Hospital</institution>
<addr-line>Boston, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Boston, MA</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="au4"><institution>Department of Pediatrics, Harvard Medical School</institution>
<addr-line>Boston, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="N Rgaard, Mette" sort="N Rgaard, Mette" uniqKey="N Rgaard M" first="Mette" last="N Rgaard">Mette N Rgaard</name>
<affiliation wicri:level="1"><nlm:aff id="au5"><institution>Department of Clinical Epidemiology, Aarhus University Hospital</institution>
<addr-line>Aarhus, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Aarhus</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Demaria, Alfred" sort="Demaria, Alfred" uniqKey="Demaria A" first="Alfred" last="Demaria">Alfred Demaria</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Massachusetts Department of Public Health, Bureau of Infectious Disease</institution>
<addr-line>Jamaica Plain, MA, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Jamaica Plain, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andreasen, Viggo" sort="Andreasen, Viggo" uniqKey="Andreasen V" first="Viggo" last="Andreasen">Viggo Andreasen</name>
<affiliation wicri:level="1"><nlm:aff id="au6"><institution>Department of Science, Systems, and Models, Roskilde University</institution>
<addr-line>Roskilde, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Roskilde</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="S Rensen, Henrik Toft" sort="S Rensen, Henrik Toft" uniqKey="S Rensen H" first="Henrik Toft" last="S Rensen">Henrik Toft S Rensen</name>
<affiliation wicri:level="1"><nlm:aff id="au5"><institution>Department of Clinical Epidemiology, Aarhus University Hospital</institution>
<addr-line>Aarhus, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Aarhus</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Influenza and Other Respiratory Viruses</title>
<idno type="ISSN">1750-2640</idno>
<idno type="eISSN">1750-2659</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Objectives</title>
<p>This study examined the association between prenatal exposure to pandemic influenza and cardiovascular events in adulthood.</p>
</sec>
<sec><title>Design</title>
<p>Using Danish surveillance data to identify months when influenza activity was highest during three previous pandemics (1918, 1957, and 1968), persons were defined as exposed/unexposed based on whether they were <italic>in utero</italic>
during peak months of one of the pandemics. Episodes of acute myocardial infarction (MI) and stroke were identified in the Danish National Registry of Patients covering all Danish hospitals since 1977.</p>
</sec>
<sec><title>Setting/Sample</title>
<p>Information from Danish national registries on all persons with a Civil Personal Registry number and birthdates in 1915 through 1922, 1954 through 1960, and 1966 through 1972 was collected.</p>
</sec>
<sec><title>Main outcome measures</title>
<p>Crude incidence rate ratios (IRRs) were calculated per pandemic. Generalized linear models were fit to estimate IRRs adjusted for sex.</p>
</sec>
<sec><title>Results</title>
<p>For acute MI, sex-adjusted IRRs for persons <italic>in uter</italic>
o during peaks of the 1918, 1957, and 1968 pandemics, compared with those born afterward, were 1·02 (95% confidence interval (CI): 0·99, 1·05), 0·96 (95% CI: 0·87, 1·05), and 1·18 (95% CI: 0·96, 1·45), respectively. For stroke, the corresponding IRRs were 0·99 (95% CI: 0·97, 1·02), 0·99 (95% CI: 0·92, 1·05), and 0·85 (95% CI: 0·77, 0·94), respectively.</p>
</sec>
<sec><title>Conclusions</title>
<p>There was generally no evidence of an association between prenatal influenza exposure and acute MI or stroke in adulthood. However, survivor bias and left truncation of outcomes for the 1918 pandemic are possible, and the current young ages of persons included in the analyses for the 1957 and 1968 pandemics may warrant later re-evaluation.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Mcneil, S" uniqKey="Mcneil S">S McNeil</name>
</author>
<author><name sortKey="Halperin, B" uniqKey="Halperin B">B Halperin</name>
</author>
<author><name sortKey="Macdonald, N" uniqKey="Macdonald N">N MacDonald</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Neuzil, Km" uniqKey="Neuzil K">KM Neuzil</name>
</author>
<author><name sortKey="Reed, Gw" uniqKey="Reed G">GW Reed</name>
</author>
<author><name sortKey="Mitchel, Ef" uniqKey="Mitchel E">EF Mitchel</name>
</author>
<author><name sortKey="Simonsen, L" uniqKey="Simonsen L">L Simonsen</name>
</author>
<author><name sortKey="Griffin, Mr" uniqKey="Griffin M">MR Griffin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jain, S" uniqKey="Jain S">S Jain</name>
</author>
<author><name sortKey="Kamimoto, L" uniqKey="Kamimoto L">L Kamimoto</name>
</author>
<author><name sortKey="Bramley, Am" uniqKey="Bramley A">AM Bramley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jamieson, Dj" uniqKey="Jamieson D">DJ Jamieson</name>
</author>
<author><name sortKey="Honein, Ma" uniqKey="Honein M">MA Honein</name>
</author>
<author><name sortKey="Rasmussen, Sa" uniqKey="Rasmussen S">SA Rasmussen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Louie, Jk" uniqKey="Louie J">JK Louie</name>
</author>
<author><name sortKey="Acosta, M" uniqKey="Acosta M">M Acosta</name>
</author>
<author><name sortKey="Winter, K" uniqKey="Winter K">K Winter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Woolston, Wj" uniqKey="Woolston W">WJ Woolston</name>
</author>
<author><name sortKey="Conley, Do" uniqKey="Conley D">DO Conley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Harris, Jw" uniqKey="Harris J">JW Harris</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Freeman, Dw" uniqKey="Freeman D">DW Freeman</name>
</author>
<author><name sortKey="Barno, A" uniqKey="Barno A">A Barno</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bloom Feshbach, K" uniqKey="Bloom Feshbach K">K Bloom-Feshbach</name>
</author>
<author><name sortKey="Simonsen, L" uniqKey="Simonsen L">L Simonsen</name>
</author>
<author><name sortKey="Viboud, C" uniqKey="Viboud C">C Viboud</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="H Berg, S" uniqKey="H Berg S">S Håberg</name>
</author>
<author><name sortKey="Trogstad, L" uniqKey="Trogstad L">L Trogstad</name>
</author>
<author><name sortKey="Gunnes, N" uniqKey="Gunnes N">N Gunnes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hardy, Jmb" uniqKey="Hardy J">JMB Hardy</name>
</author>
<author><name sortKey="Azarowicz, En" uniqKey="Azarowicz E">EN Azarowicz</name>
</author>
<author><name sortKey="Mannini, A" uniqKey="Mannini A">A Mannini</name>
</author>
<author><name sortKey="Medearis, Dn" uniqKey="Medearis D">DN Medearis</name>
</author>
<author><name sortKey="Cooke, Re" uniqKey="Cooke R">RE Cooke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lieberman, Rw" uniqKey="Lieberman R">RW Lieberman</name>
</author>
<author><name sortKey="Bagdasarian, N" uniqKey="Bagdasarian N">N Bagdasarian</name>
</author>
<author><name sortKey="Thomas, D" uniqKey="Thomas D">D Thomas</name>
</author>
<author><name sortKey="Van De Ven, C" uniqKey="Van De Ven C">C Van De Ven</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stanwell Smith, R" uniqKey="Stanwell Smith R">R Stanwell-Smith</name>
</author>
<author><name sortKey="Parker, Am" uniqKey="Parker A">AM Parker</name>
</author>
<author><name sortKey="Chakraverty, P" uniqKey="Chakraverty P">P Chakraverty</name>
</author>
<author><name sortKey="Soltanpoor, N" uniqKey="Soltanpoor N">N Soltanpoor</name>
</author>
<author><name sortKey="Simpson, Cn" uniqKey="Simpson C">CN Simpson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Munoz, Fm" uniqKey="Munoz F">FM Munoz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yusuf, K" uniqKey="Yusuf K">K Yusuf</name>
</author>
<author><name sortKey="Soraisham, As" uniqKey="Soraisham A">AS Soraisham</name>
</author>
<author><name sortKey="Fonseca, K" uniqKey="Fonseca K">K Fonseca</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Adams, W" uniqKey="Adams W">W Adams</name>
</author>
<author><name sortKey="Kendell, Re" uniqKey="Kendell R">RE Kendell</name>
</author>
<author><name sortKey="Hare, Eh" uniqKey="Hare E">EH Hare</name>
</author>
<author><name sortKey="Munk Jorgensen, P" uniqKey="Munk Jorgensen P">P Munk-Jorgensen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kunugi, H" uniqKey="Kunugi H">H Kunugi</name>
</author>
<author><name sortKey="Nanko, S" uniqKey="Nanko S">S Nanko</name>
</author>
<author><name sortKey="Takei, N" uniqKey="Takei N">N Takei</name>
</author>
<author><name sortKey="Saito, K" uniqKey="Saito K">K Saito</name>
</author>
<author><name sortKey="Hayashi, N" uniqKey="Hayashi N">N Hayashi</name>
</author>
<author><name sortKey="Kazamatsuri, H" uniqKey="Kazamatsuri H">H Kazamatsuri</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="O Callaghan, E" uniqKey="O Callaghan E">E O'Callaghan</name>
</author>
<author><name sortKey="Sham, P" uniqKey="Sham P">P Sham</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Selten, J" uniqKey="Selten J">J Selten</name>
</author>
<author><name sortKey="Brown, As" uniqKey="Brown A">AS Brown</name>
</author>
<author><name sortKey="Moons, Kgm" uniqKey="Moons K">KGM Moons</name>
</author>
<author><name sortKey="Slaets, Jpj" uniqKey="Slaets J">JPJ Slaets</name>
</author>
<author><name sortKey="Susser, Es" uniqKey="Susser E">ES Susser</name>
</author>
<author><name sortKey="Kahn, Rs" uniqKey="Kahn R">RS Kahn</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Selten, J" uniqKey="Selten J">J Selten</name>
</author>
<author><name sortKey="Frissen, A" uniqKey="Frissen A">A Frissen</name>
</author>
<author><name sortKey="Lensvelt Mulders, G" uniqKey="Lensvelt Mulders G">G Lensvelt-Mulders</name>
</author>
<author><name sortKey="Morgan, Va" uniqKey="Morgan V">VA Morgan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Takei, N" uniqKey="Takei N">N Takei</name>
</author>
<author><name sortKey="Mortensen, Pb" uniqKey="Mortensen P">PB Mortensen</name>
</author>
<author><name sortKey="Klaening, U" uniqKey="Klaening U">U Klaening</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cohen, Aa" uniqKey="Cohen A">AA Cohen</name>
</author>
<author><name sortKey="Tillinghast, J" uniqKey="Tillinghast J">J Tillinghast</name>
</author>
<author><name sortKey="Canudas Romo, V" uniqKey="Canudas Romo V">V Canudas-Romo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Almond, D" uniqKey="Almond D">D Almond</name>
</author>
<author><name sortKey="Mazumder, B" uniqKey="Mazumder B">B Mazumder</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mazumder, B" uniqKey="Mazumder B">B Mazumder</name>
</author>
<author><name sortKey="Almond, D" uniqKey="Almond D">D Almond</name>
</author>
<author><name sortKey="Park, K" uniqKey="Park K">K Park</name>
</author>
<author><name sortKey="Crimmins, Em" uniqKey="Crimmins E">EM Crimmins</name>
</author>
<author><name sortKey="Finch, Ce" uniqKey="Finch C">CE Finch</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Frank, L" uniqKey="Frank L">L Frank</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Rothman, K" uniqKey="Rothman K">K Rothman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Andreasen, V" uniqKey="Andreasen V">V Andreasen</name>
</author>
<author><name sortKey="Viboud, C" uniqKey="Viboud C">C Viboud</name>
</author>
<author><name sortKey="Simonsen, L" uniqKey="Simonsen L">L Simonsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Davis, Le" uniqKey="Davis L">LE Davis</name>
</author>
<author><name sortKey="Caldwell, Gg" uniqKey="Caldwell G">GG Caldwell</name>
</author>
<author><name sortKey="Lynch, Re" uniqKey="Lynch R">RE Lynch</name>
</author>
<author><name sortKey="Bailey, Re" uniqKey="Bailey R">RE Bailey</name>
</author>
<author><name sortKey="Chin, Tdy" uniqKey="Chin T">TDY Chin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dunn, Fl" uniqKey="Dunn F">FL Dunn</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Payne, L" uniqKey="Payne L">L Payne</name>
</author>
<author><name sortKey="Kuhlmann Berenzon, S" uniqKey="Kuhlmann Berenzon S">S Kühlmann-Berenzon</name>
</author>
<author><name sortKey="Ekdahl, K" uniqKey="Ekdahl K">K Ekdahl</name>
</author>
<author><name sortKey="Giesecke, J" uniqKey="Giesecke J">J Giesecke</name>
</author>
<author><name sortKey="Hogberg, L" uniqKey="Hogberg L">L Högberg</name>
</author>
<author><name sortKey="Penttinen, P" uniqKey="Penttinen P">P Penttinen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Steinhoff, Mc" uniqKey="Steinhoff M">MC Steinhoff</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Greenland, S" uniqKey="Greenland S">S Greenland</name>
</author>
<author><name sortKey="Lash, Tl" uniqKey="Lash T">TL Lash</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fox, Mp" uniqKey="Fox M">MP Fox</name>
</author>
<author><name sortKey="Lash, Tl" uniqKey="Lash T">TL Lash</name>
</author>
<author><name sortKey="Greenland, S" uniqKey="Greenland S">S Greenland</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Viboud, C" uniqKey="Viboud C">C Viboud</name>
</author>
<author><name sortKey="Grais, Re" uniqKey="Grais R">RE Grais</name>
</author>
<author><name sortKey="Lafont, Bap" uniqKey="Lafont B">BAP Lafont</name>
</author>
<author><name sortKey="Miller, Ma" uniqKey="Miller M">MA Miller</name>
</author>
<author><name sortKey="Simonsen, L" uniqKey="Simonsen L">L Simonsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Johnsen, Sp" uniqKey="Johnsen S">SP Johnsen</name>
</author>
<author><name sortKey="Overvad, K" uniqKey="Overvad K">K Overvad</name>
</author>
<author><name sortKey="S Rensen, Ht" uniqKey="S Rensen H">HT Sørensen</name>
</author>
<author><name sortKey="Tj Nneland, A" uniqKey="Tj Nneland A">A Tjønneland</name>
</author>
<author><name sortKey="Husted, Se" uniqKey="Husted S">SE Husted</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Krarup, L" uniqKey="Krarup L">L Krarup</name>
</author>
<author><name sortKey="Boysen, G" uniqKey="Boysen G">G Boysen</name>
</author>
<author><name sortKey="Janjua, H" uniqKey="Janjua H">H Janjua</name>
</author>
<author><name sortKey="Prescott, E" uniqKey="Prescott E">E Prescott</name>
</author>
<author><name sortKey="Truelsen, T" uniqKey="Truelsen T">T Truelsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mamelund, S" uniqKey="Mamelund S">S Mamelund</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rothman, Kj" uniqKey="Rothman K">KJ Rothman</name>
</author>
<author><name sortKey="Poole, C" uniqKey="Poole C">C Poole</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barker, Djp" uniqKey="Barker D">DJP Barker</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mone, Sm" uniqKey="Mone S">SM Mone</name>
</author>
<author><name sortKey="Gillman, Mw" uniqKey="Gillman M">MW Gillman</name>
</author>
<author><name sortKey="Miller, Tl" uniqKey="Miller T">TL Miller</name>
</author>
<author><name sortKey="Herman, Eh" uniqKey="Herman E">EH Herman</name>
</author>
<author><name sortKey="Lipshultz, Se" uniqKey="Lipshultz S">SE Lipshultz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rajaleid, K" uniqKey="Rajaleid K">K Rajaleid</name>
</author>
<author><name sortKey="Janszky, I" uniqKey="Janszky I">I Janszky</name>
</author>
<author><name sortKey="Hallqvist, J" uniqKey="Hallqvist J">J Hallqvist</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Samuelsson, A" uniqKey="Samuelsson A">A Samuelsson</name>
</author>
<author><name sortKey="Ohrn, I" uniqKey="Ohrn I">I Ohrn</name>
</author>
<author><name sortKey="Dahlgren, J" uniqKey="Dahlgren J">J Dahlgren</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Samuelsson, A" uniqKey="Samuelsson A">A Samuelsson</name>
</author>
<author><name sortKey="Alexanderson, C" uniqKey="Alexanderson C">C Alexanderson</name>
</author>
<author><name sortKey="Molne, J" uniqKey="Molne J">J Molne</name>
</author>
<author><name sortKey="Haraldsson, B" uniqKey="Haraldsson B">B Haraldsson</name>
</author>
<author><name sortKey="Hansell, P" uniqKey="Hansell P">P Hansell</name>
</author>
<author><name sortKey="Holmang, A" uniqKey="Holmang A">A Holmang</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Influenza Other Respir Viruses</journal-id>
<journal-id journal-id-type="iso-abbrev">Influenza Other Respir Viruses</journal-id>
<journal-id journal-id-type="publisher-id">irv</journal-id>
<journal-title-group><journal-title>Influenza and Other Respiratory Viruses</journal-title>
</journal-title-group>
<issn pub-type="ppub">1750-2640</issn>
<issn pub-type="epub">1750-2659</issn>
<publisher><publisher-name>Blackwell Publishing Ltd</publisher-name>
<publisher-loc>Oxford, UK</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">24373293</article-id>
<article-id pub-id-type="pmc">4177801</article-id>
<article-id pub-id-type="doi">10.1111/irv.12202</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Articles</subject>
</subj-group>
</article-categories>
<title-group><article-title>Prenatal influenza exposure and cardiovascular events in adulthood</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Cocoros</surname>
<given-names>Noelle M</given-names>
</name>
<xref ref-type="aff" rid="au1">a</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lash</surname>
<given-names>Timothy L</given-names>
</name>
<xref ref-type="aff" rid="au2">b</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ozonoff</surname>
<given-names>Al</given-names>
</name>
<xref ref-type="aff" rid="au3">c</xref>
<xref ref-type="aff" rid="au4">d</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nørgaard</surname>
<given-names>Mette</given-names>
</name>
<xref ref-type="aff" rid="au5">e</xref>
</contrib>
<contrib contrib-type="author"><name><surname>DeMaria</surname>
<given-names>Alfred</given-names>
<suffix>Jr</suffix>
</name>
<xref ref-type="aff" rid="au1">a</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Andreasen</surname>
<given-names>Viggo</given-names>
</name>
<xref ref-type="aff" rid="au6">f</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sørensen</surname>
<given-names>Henrik Toft</given-names>
</name>
<xref ref-type="aff" rid="au5">e</xref>
</contrib>
<aff id="au1"><label>a</label>
<institution>Massachusetts Department of Public Health, Bureau of Infectious Disease</institution>
<addr-line>Jamaica Plain, MA, USA</addr-line>
</aff>
<aff id="au2"><label>b</label>
<institution>Department of Epidemiology, Rollins School of Public Health, Emory University</institution>
<addr-line>Atlanta, GA, USA</addr-line>
</aff>
<aff id="au3"><label>c</label>
<institution>Center for Patient Safety and Quality Research, Program for Patient Safety and Quality, Boston Children's Hospital</institution>
<addr-line>Boston, MA, USA</addr-line>
</aff>
<aff id="au4"><label>d</label>
<institution>Department of Pediatrics, Harvard Medical School</institution>
<addr-line>Boston, MA, USA</addr-line>
</aff>
<aff id="au5"><label>e</label>
<institution>Department of Clinical Epidemiology, Aarhus University Hospital</institution>
<addr-line>Aarhus, Denmark</addr-line>
</aff>
<aff id="au6"><label>f</label>
<institution>Department of Science, Systems, and Models, Roskilde University</institution>
<addr-line>Roskilde, Denmark</addr-line>
</aff>
</contrib-group>
<author-notes><corresp id="cor1">Noelle M. Cocoros, Massachusetts Department of Public Health, 305 South Street, Jamaica Plain, MA 02130, USA. E-mail: <email>noelle.cocoros@state.ma.us</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>1</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub"><day>07</day>
<month>11</month>
<year>2013</year>
</pub-date>
<volume>8</volume>
<issue>1</issue>
<fpage>83</fpage>
<lpage>90</lpage>
<history><date date-type="accepted"><day>21</day>
<month>9</month>
<year>2013</year>
</date>
</history>
<permissions><copyright-statement>© 2013 The Authors. <italic>Influenza and Other Respiratory Viruses</italic>
Published by John Wiley & Sons Ltd.</copyright-statement>
<copyright-year>2013</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><sec><title>Objectives</title>
<p>This study examined the association between prenatal exposure to pandemic influenza and cardiovascular events in adulthood.</p>
</sec>
<sec><title>Design</title>
<p>Using Danish surveillance data to identify months when influenza activity was highest during three previous pandemics (1918, 1957, and 1968), persons were defined as exposed/unexposed based on whether they were <italic>in utero</italic>
during peak months of one of the pandemics. Episodes of acute myocardial infarction (MI) and stroke were identified in the Danish National Registry of Patients covering all Danish hospitals since 1977.</p>
</sec>
<sec><title>Setting/Sample</title>
<p>Information from Danish national registries on all persons with a Civil Personal Registry number and birthdates in 1915 through 1922, 1954 through 1960, and 1966 through 1972 was collected.</p>
</sec>
<sec><title>Main outcome measures</title>
<p>Crude incidence rate ratios (IRRs) were calculated per pandemic. Generalized linear models were fit to estimate IRRs adjusted for sex.</p>
</sec>
<sec><title>Results</title>
<p>For acute MI, sex-adjusted IRRs for persons <italic>in uter</italic>
o during peaks of the 1918, 1957, and 1968 pandemics, compared with those born afterward, were 1·02 (95% confidence interval (CI): 0·99, 1·05), 0·96 (95% CI: 0·87, 1·05), and 1·18 (95% CI: 0·96, 1·45), respectively. For stroke, the corresponding IRRs were 0·99 (95% CI: 0·97, 1·02), 0·99 (95% CI: 0·92, 1·05), and 0·85 (95% CI: 0·77, 0·94), respectively.</p>
</sec>
<sec><title>Conclusions</title>
<p>There was generally no evidence of an association between prenatal influenza exposure and acute MI or stroke in adulthood. However, survivor bias and left truncation of outcomes for the 1918 pandemic are possible, and the current young ages of persons included in the analyses for the 1957 and 1968 pandemics may warrant later re-evaluation.</p>
</sec>
</abstract>
<kwd-group><kwd>Acute myocardial infarction</kwd>
<kwd>influenza</kwd>
<kwd>pandemic</kwd>
<kwd>stroke</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000985 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 000985 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= H2N2V1 |flux= Pmc |étape= Curation |type= RBID |clé= PMC:4177801 |texte= Prenatal influenza exposure and cardiovascular events in adulthood }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:24373293" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \ | NlmPubMed2Wicri -a H2N2V1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |