Beyond Antigenic Match: Possible Agent-Host and Immuno-epidemiological Influences on Influenza Vaccine Effectiveness During the 2015–2016 Season in Canada
Identifieur interne : 000258 ( Pmc/Checkpoint ); précédent : 000257; suivant : 000259Beyond Antigenic Match: Possible Agent-Host and Immuno-epidemiological Influences on Influenza Vaccine Effectiveness During the 2015–2016 Season in Canada
Auteurs : Danuta M. Skowronski ; Catharine Chambers ; Suzana Sabaiduc ; Gaston De Serres ; Anne-Luise Winter ; James A. Dickinson [Canada] ; Jonathan B. Gubbay [Canada] ; Steven J. Drews ; Christine Martineau ; Hugues Charest ; Mel Krajden ; Nathalie Bastien [Canada] ; Yan Li [Canada]Source :
- The Journal of Infectious Diseases [ 0022-1899 ] ; 2017.
Abstract
Vaccine effectiveness estimates for 2015–2016 seasonal influenza vaccine are reported from Canada. Findings suggest that agent-host and immuno-epidemiologic factors beyond antigenic match—including viral genomic variation, birth (immunological) cohort effects, repeat vaccination, and potential within-season waning immunity—may influence vaccine performance.
Url:
DOI: 10.1093/infdis/jix526
PubMed: 29029166
PubMed Central: 5853508
Affiliations:
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PMC:5853508Le document en format XML
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Skowronski</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0002">University of British Columbia, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Chambers, Catharine" sort="Chambers, Catharine" uniqKey="Chambers C" first="Catharine" last="Chambers">Catharine Chambers</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Sabaiduc, Suzana" sort="Sabaiduc, Suzana" uniqKey="Sabaiduc S" first="Suzana" last="Sabaiduc">Suzana Sabaiduc</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><affiliation><nlm:aff id="AF0003">Institut National de Santé Publique du Québec</nlm:aff></affiliation><affiliation><nlm:aff id="AF0004">Laval University, Québec</nlm:aff><wicri:noCountry code="subfield">Québec</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0005">Centre Hospitalier Universitaire de Québec, Québec</nlm:aff><wicri:noCountry code="subfield">Québec</wicri:noCountry></affiliation></author><author><name sortKey="Winter, Anne Luise" sort="Winter, Anne Luise" uniqKey="Winter A" first="Anne-Luise" last="Winter">Anne-Luise Winter</name><affiliation><nlm:aff id="AF0006">Public Health Ontario, Toronto</nlm:aff><wicri:noCountry code="subfield">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Dickinson, James A" sort="Dickinson, James A" uniqKey="Dickinson J" first="James A" last="Dickinson">James A. Dickinson</name><affiliation wicri:level="4"><nlm:aff id="AF0007">University of Calgary, Calgary</nlm:aff><orgName type="university">Université de Calgary</orgName><country>Canada</country><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B" last="Gubbay">Jonathan B. Gubbay</name><affiliation><nlm:aff id="AF0006">Public Health Ontario, Toronto</nlm:aff><wicri:noCountry code="subfield">Toronto</wicri:noCountry></affiliation><affiliation wicri:level="4"><nlm:aff id="AF0008">University of Toronto, Toronto</nlm:aff><orgName type="university">Université de Toronto</orgName><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Drews, Steven J" sort="Drews, Steven J" uniqKey="Drews S" first="Steven J" last="Drews">Steven J. Drews</name><affiliation><nlm:aff id="AF0009">Alberta Provincial Laboratory, Edmonton</nlm:aff><wicri:noCountry code="subfield">Edmonton</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0010">University of Alberta, Edmonton</nlm:aff><wicri:noCountry code="subfield">Edmonton</wicri:noCountry></affiliation></author><author><name sortKey="Martineau, Christine" sort="Martineau, Christine" uniqKey="Martineau C" first="Christine" last="Martineau">Christine Martineau</name><affiliation><nlm:aff id="AF0003">Institut National de Santé Publique du Québec</nlm:aff></affiliation></author><author><name sortKey="Charest, Hugues" sort="Charest, Hugues" uniqKey="Charest H" first="Hugues" last="Charest">Hugues Charest</name><affiliation><nlm:aff id="AF0003">Institut National de Santé Publique du Québec</nlm:aff></affiliation></author><author><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0002">University of British Columbia, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><affiliation wicri:level="1"><nlm:aff id="AF0011">National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg</wicri:regionArea><wicri:noRegion>Winnipeg</wicri:noRegion></affiliation></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><affiliation wicri:level="1"><nlm:aff id="AF0011">National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg</wicri:regionArea><wicri:noRegion>Winnipeg</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">29029166</idno><idno type="pmc">5853508</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853508</idno><idno type="RBID">PMC:5853508</idno><idno type="doi">10.1093/infdis/jix526</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">000A11</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000A11</idno><idno type="wicri:Area/Pmc/Curation">000A11</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000A11</idno><idno type="wicri:Area/Pmc/Checkpoint">000258</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000258</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Beyond Antigenic Match: Possible Agent-Host and Immuno-epidemiological Influences on Influenza Vaccine Effectiveness During the 2015–2016 Season in Canada</title><author><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M" last="Skowronski">Danuta M. Skowronski</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0002">University of British Columbia, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Chambers, Catharine" sort="Chambers, Catharine" uniqKey="Chambers C" first="Catharine" last="Chambers">Catharine Chambers</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Sabaiduc, Suzana" sort="Sabaiduc, Suzana" uniqKey="Sabaiduc S" first="Suzana" last="Sabaiduc">Suzana Sabaiduc</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><affiliation><nlm:aff id="AF0003">Institut National de Santé Publique du Québec</nlm:aff></affiliation><affiliation><nlm:aff id="AF0004">Laval University, Québec</nlm:aff><wicri:noCountry code="subfield">Québec</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0005">Centre Hospitalier Universitaire de Québec, Québec</nlm:aff><wicri:noCountry code="subfield">Québec</wicri:noCountry></affiliation></author><author><name sortKey="Winter, Anne Luise" sort="Winter, Anne Luise" uniqKey="Winter A" first="Anne-Luise" last="Winter">Anne-Luise Winter</name><affiliation><nlm:aff id="AF0006">Public Health Ontario, Toronto</nlm:aff><wicri:noCountry code="subfield">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Dickinson, James A" sort="Dickinson, James A" uniqKey="Dickinson J" first="James A" last="Dickinson">James A. Dickinson</name><affiliation wicri:level="4"><nlm:aff id="AF0007">University of Calgary, Calgary</nlm:aff><orgName type="university">Université de Calgary</orgName><country>Canada</country><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B" last="Gubbay">Jonathan B. Gubbay</name><affiliation><nlm:aff id="AF0006">Public Health Ontario, Toronto</nlm:aff><wicri:noCountry code="subfield">Toronto</wicri:noCountry></affiliation><affiliation wicri:level="4"><nlm:aff id="AF0008">University of Toronto, Toronto</nlm:aff><orgName type="university">Université de Toronto</orgName><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Drews, Steven J" sort="Drews, Steven J" uniqKey="Drews S" first="Steven J" last="Drews">Steven J. Drews</name><affiliation><nlm:aff id="AF0009">Alberta Provincial Laboratory, Edmonton</nlm:aff><wicri:noCountry code="subfield">Edmonton</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0010">University of Alberta, Edmonton</nlm:aff><wicri:noCountry code="subfield">Edmonton</wicri:noCountry></affiliation></author><author><name sortKey="Martineau, Christine" sort="Martineau, Christine" uniqKey="Martineau C" first="Christine" last="Martineau">Christine Martineau</name><affiliation><nlm:aff id="AF0003">Institut National de Santé Publique du Québec</nlm:aff></affiliation></author><author><name sortKey="Charest, Hugues" sort="Charest, Hugues" uniqKey="Charest H" first="Hugues" last="Charest">Hugues Charest</name><affiliation><nlm:aff id="AF0003">Institut National de Santé Publique du Québec</nlm:aff></affiliation></author><author><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><affiliation><nlm:aff id="AF0001">British Columbia Centre for Disease Control, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation><affiliation><nlm:aff id="AF0002">University of British Columbia, Vancouver</nlm:aff><wicri:noCountry code="subfield">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><affiliation wicri:level="1"><nlm:aff id="AF0011">National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg</wicri:regionArea><wicri:noRegion>Winnipeg</wicri:noRegion></affiliation></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><affiliation wicri:level="1"><nlm:aff id="AF0011">National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg</wicri:regionArea><wicri:noRegion>Winnipeg</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Journal of Infectious Diseases</title><idno type="ISSN">0022-1899</idno><idno type="eISSN">1537-6613</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Vaccine effectiveness estimates for 2015–2016 seasonal influenza vaccine are reported from Canada. Findings suggest that agent-host and immuno-epidemiologic factors beyond antigenic match—including viral genomic variation, birth (immunological) cohort effects, repeat vaccination, and potential within-season waning immunity—may influence vaccine performance.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM Skowronski</name></author><author><name sortKey="Chambers, C" uniqKey="Chambers C">C Chambers</name></author><author><name sortKey="Sabaiduc, S" uniqKey="Sabaiduc S">S Sabaiduc</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Epperson, S" uniqKey="Epperson S">S Epperson</name></author><author><name sortKey="Blanton, L" uniqKey="Blanton L">L Blanton</name></author><author><name sortKey="Kniss, K" uniqKey="Kniss K">K 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Kissling</name></author><author><name sortKey="Reuss, A" uniqKey="Reuss A">A Reuss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Flannery, B" uniqKey="Flannery B">B Flannery</name></author><author><name sortKey="Chung, J" uniqKey="Chung J">J Chung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ambrose, C" uniqKey="Ambrose C">C Ambrose</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pebody, R" uniqKey="Pebody R">R Pebody</name></author><author><name sortKey="Warburton, F" uniqKey="Warburton F">F Warburton</name></author><author><name sortKey="Ellis, J" uniqKey="Ellis J">J Ellis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tate, Md" uniqKey="Tate M">MD Tate</name></author><author><name sortKey="Job, Er" uniqKey="Job E">ER Job</name></author><author><name sortKey="Deng, Ym" uniqKey="Deng Y">YM Deng</name></author><author><name sortKey="Gunalan, V" uniqKey="Gunalan V">V Gunalan</name></author><author><name sortKey="Maurer Stroh, S" uniqKey="Maurer Stroh S">S Maurer-Stroh</name></author><author><name sortKey="Reading, Pc" uniqKey="Reading P">PC Reading</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kissling, E" uniqKey="Kissling E">E Kissling</name></author><author><name sortKey="Valenciano, M" uniqKey="Valenciano M">M Valenciano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jimenez Jorge, S" uniqKey="Jimenez Jorge S">S Jiménez-Jorge</name></author><author><name sortKey="Savulescu, C" uniqKey="Savulescu C">C Savulescu</name></author><author><name sortKey="Pozo, F" uniqKey="Pozo F">F Pozo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gostic, Km" uniqKey="Gostic K">KM Gostic</name></author><author><name sortKey="Ambrose, M" uniqKey="Ambrose M">M Ambrose</name></author><author><name sortKey="Worobey, M" uniqKey="Worobey M">M Worobey</name></author><author><name sortKey="Lloyd Smith, Jo" uniqKey="Lloyd Smith J">JO Lloyd-Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Te Beest, De" uniqKey="Te Beest D">DE Te Beest</name></author><author><name sortKey="De Bruin, E" uniqKey="De Bruin E">E de Bruin</name></author><author><name sortKey="Imholz, S" uniqKey="Imholz S">S Imholz</name></author><author><name sortKey="Koopmans, M" uniqKey="Koopmans M">M Koopmans</name></author><author><name sortKey="Van Boven, M" uniqKey="Van Boven M">M van Boven</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Monto, As" uniqKey="Monto A">AS Monto</name></author><author><name sortKey="Malosh, Re" uniqKey="Malosh R">RE Malosh</name></author><author><name sortKey="Petrie, Jg" uniqKey="Petrie J">JG Petrie</name></author><author><name sortKey="Martin, Et" uniqKey="Martin E">ET Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM Skowronski</name></author><author><name sortKey="Hottes, Ts" uniqKey="Hottes T">TS Hottes</name></author><author><name sortKey="Mcelhaney, Je" uniqKey="Mcelhaney J">JE McElhaney</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM Skowronski</name></author><author><name sortKey="Chambers, C" uniqKey="Chambers C">C Chambers</name></author><author><name sortKey="Sabaiduc, S" uniqKey="Sabaiduc S">S Sabaiduc</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM Skowronski</name></author><author><name sortKey="Hamelin, Me" uniqKey="Hamelin M">ME Hamelin</name></author><author><name sortKey="Janjua, Nz" uniqKey="Janjua N">NZ Janjua</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM Skowronski</name></author><author><name sortKey="Hottes, Ts" uniqKey="Hottes T">TS Hottes</name></author><author><name sortKey="De Serres, G" uniqKey="De Serres G">G De Serres</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tricco, Ac" uniqKey="Tricco A">AC Tricco</name></author><author><name sortKey="Chit, A" uniqKey="Chit A">A Chit</name></author><author><name sortKey="Soobiah, C" uniqKey="Soobiah C">C Soobiah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM Skowronski</name></author><author><name sortKey="Chambers, C" uniqKey="Chambers C">C Chambers</name></author><author><name sortKey="De Serres, G" uniqKey="De Serres G">G De Serres</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Robertson, Js" uniqKey="Robertson J">JS Robertson</name></author><author><name sortKey="Naeve, Cw" uniqKey="Naeve C">CW Naeve</name></author><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author><author><name sortKey="Bootman, Js" uniqKey="Bootman J">JS Bootman</name></author><author><name sortKey="Newman, R" uniqKey="Newman R">R Newman</name></author><author><name sortKey="Schild, Gc" uniqKey="Schild G">GC Schild</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">J. Infect. Dis</journal-id><journal-id journal-id-type="publisher-id">jid</journal-id><journal-title-group><journal-title>The Journal of Infectious Diseases</journal-title></journal-title-group><issn pub-type="ppub">0022-1899</issn><issn pub-type="epub">1537-6613</issn><publisher><publisher-name>Oxford University Press</publisher-name><publisher-loc>US</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">29029166</article-id><article-id pub-id-type="pmc">5853508</article-id><article-id pub-id-type="doi">10.1093/infdis/jix526</article-id><article-id pub-id-type="publisher-id">jix526</article-id><article-categories><subj-group subj-group-type="heading"><subject>Major Articles and Brief Reports</subject><subj-group subj-group-type="category-toc-heading"><subject>Viruses</subject></subj-group></subj-group></article-categories><title-group><article-title>Beyond Antigenic Match: Possible Agent-Host and Immuno-epidemiological Influences on Influenza Vaccine Effectiveness During the 2015–2016 Season in Canada</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Skowronski</surname><given-names>Danuta M</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="corresp" rid="c1"></xref><pmc-comment>Danuta.Skowronski@bccdc.ca </pmc-comment>
</contrib><contrib contrib-type="author"><name><surname>Chambers</surname><given-names>Catharine</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Sabaiduc</surname><given-names>Suzana</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>De Serres</surname><given-names>Gaston</given-names></name><xref ref-type="aff" rid="AF0003">3</xref><xref ref-type="aff" rid="AF0004">4</xref><xref ref-type="aff" rid="AF0005">5</xref></contrib><contrib contrib-type="author"><name><surname>Winter</surname><given-names>Anne-Luise</given-names></name><xref ref-type="aff" rid="AF0006">6</xref></contrib><contrib contrib-type="author"><name><surname>Dickinson</surname><given-names>James A</given-names></name><xref ref-type="aff" rid="AF0007">7</xref></contrib><contrib contrib-type="author"><name><surname>Gubbay</surname><given-names>Jonathan B</given-names></name><xref ref-type="aff" rid="AF0006">6</xref><xref ref-type="aff" rid="AF0008">8</xref></contrib><contrib contrib-type="author"><name><surname>Drews</surname><given-names>Steven J</given-names></name><xref ref-type="aff" rid="AF0009">9</xref><xref ref-type="aff" rid="AF0010">10</xref></contrib><contrib contrib-type="author"><name><surname>Martineau</surname><given-names>Christine</given-names></name><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Charest</surname><given-names>Hugues</given-names></name><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Krajden</surname><given-names>Mel</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Bastien</surname><given-names>Nathalie</given-names></name><xref ref-type="aff" rid="AF0011">11</xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Yan</given-names></name><xref ref-type="aff" rid="AF0011">11</xref></contrib></contrib-group><aff id="AF0001"><label>1</label>British Columbia Centre for Disease Control, Vancouver</aff><aff id="AF0002"><label>2</label>University of British Columbia, Vancouver</aff><aff id="AF0003"><label>3</label>Institut National de Santé Publique du Québec</aff><aff id="AF0004"><label>4</label>Laval University, Québec</aff><aff id="AF0005"><label>5</label>Centre Hospitalier Universitaire de Québec, Québec</aff><aff id="AF0006"><label>6</label>Public Health Ontario, Toronto</aff><aff id="AF0008"><label>8</label>University of Toronto, Toronto</aff><aff id="AF0007"><label>7</label>University of Calgary, Calgary</aff><aff id="AF0009"><label>9</label>Alberta Provincial Laboratory, Edmonton</aff><aff id="AF0010"><label>10</label>University of Alberta, Edmonton</aff><aff id="AF0011"><label>11</label>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada</aff><author-notes><corresp id="c1">Correspondence: D. M. Skowronski MD, FRCPC, BC Centre for Disease Control, 655 W 12th Ave, Vancouver, British Columbia, Canada V5Z 4R4 (<email>Danuta.Skowronski@bccdc.ca</email>).</corresp></author-notes><pub-date pub-type="ppub"><day>15</day><month>12</month><year>2017</year></pub-date><pub-date pub-type="epub" iso-8601-date="2017-10-04"><day>04</day><month>10</month><year>2017</year></pub-date><pub-date pub-type="pmc-release"><day>04</day><month>10</month><year>2017</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>216</volume><issue>12</issue><fpage>1487</fpage><lpage>1500</lpage><permissions><copyright-statement>© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.</copyright-statement><copyright-year>2017</copyright-year><license license-type="cc-by-nc-nd" xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/">http://creativecommons.org/licenses/by-nc-nd/4.0/</ext-link>), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com</license-p></license></permissions><self-uri xlink:href="jix526.pdf"></self-uri><related-article id="d35e209" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/infdis/jix527"></related-article><abstract abstract-type="teaser"><p>Vaccine effectiveness estimates for 2015–2016 seasonal influenza vaccine are reported from Canada. Findings suggest that agent-host and immuno-epidemiologic factors beyond antigenic match—including viral genomic variation, birth (immunological) cohort effects, repeat vaccination, and potential within-season waning immunity—may influence vaccine performance.</p></abstract><abstract><title>Abstract</title><sec id="s1"><title>Background</title><p>Vaccine effectiveness (VE) estimates for 2015–2016 seasonal influenza vaccine are reported from Canada’s Sentinel Practitioner Surveillance Network (SPSN). This season was characterized by a delayed 2009 pandemic influenza A(H1N1) virus (A[H1N1]pdm09) epidemic and concurrent influenza B(Victoria) virus activity. Potential influences on VE beyond antigenic match are explored, including viral genomic variation, birth cohort effects, prior vaccination, and epidemic period.</p></sec><sec id="s2"><title>Methods</title><p>VE was estimated by a test-negative design comparing the adjusted odds ratio for influenza test positivity among vaccinated compared to unvaccinated participants. Vaccine-virus relatedness was assessed by gene sequencing and hemagglutination inhibition assay.</p></sec><sec id="s3"><title>Results</title><p>Analyses included 596 influenza A(H1N1)pdm09 and 305 B(Victoria) cases and 926 test-negative controls. A(H1N1)pdm09 viruses were considered antigenically related to vaccine (unchanged since 2009), despite phylogenetic clustering within emerging clade 6B.1. The adjusted VE against A(H1N1)pdm09 was 43% (95% confidence interval [CI], 25%–57%). Compared to other age groups, VE against A(H1N1)pdm09 was lower for adults born during 1957–1976 (25%; 95% CI, −16%–51%). The VE against A(H1N1)pdm09 was also lower for participants consecutively vaccinated during both the current and prior seasons (41%; 95% CI, 18%–57%) than for those vaccinated during the current season only (75%; 95% CI, 45%–88%), and the VE among participants presenting in March–April 2016 (19%; 95% CI, −15%–44%) was lower than that among those presenting during January–February 2016 (62%; 95% CI, 44%–74%). The adjusted VE for B(Victoria) viruses was 54% (95% CI, 32%–68%), despite lineage-level mismatch to B(Yamagata) vaccine. The further variation in VE as observed for A(H1N1)pdm09 was not observed for B(Victoria).</p></sec><sec id="s4"><title>Conclusions</title><p>Influenza VE findings may require consideration of other agent-host and immuno-epidemiologic influences on vaccine performance beyond antigenic match, including viral genomic variation, repeat vaccination, birth (immunological) cohort effects, and potential within-season waning of vaccine protection.</p></sec></abstract><kwd-group><kwd>Influenza</kwd><kwd>influenza vaccine</kwd><kwd>vaccine effectiveness</kwd><kwd>influenza A subtype</kwd><kwd>influenza B lineage</kwd><kwd>sequencing</kwd><kwd>hemagglutination inhibition</kwd><kwd>birth cohort effects</kwd><kwd>original antigenic sin</kwd><kwd>repeat vaccination</kwd></kwd-group><counts><page-count count="14"></page-count></counts></article-meta></front></pmc><affiliations><list><country><li>Canada</li></country><region><li>Alberta</li><li>Ontario</li></region><settlement><li>Calgary</li><li>Toronto</li></settlement><orgName><li>Université de Calgary</li><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Chambers, Catharine" sort="Chambers, Catharine" uniqKey="Chambers C" first="Catharine" last="Chambers">Catharine Chambers</name><name sortKey="Charest, Hugues" sort="Charest, Hugues" uniqKey="Charest H" first="Hugues" last="Charest">Hugues Charest</name><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><name sortKey="Drews, Steven J" sort="Drews, Steven J" uniqKey="Drews S" first="Steven J" last="Drews">Steven J. Drews</name><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><name sortKey="Martineau, Christine" sort="Martineau, Christine" uniqKey="Martineau C" first="Christine" last="Martineau">Christine Martineau</name><name sortKey="Sabaiduc, Suzana" sort="Sabaiduc, Suzana" uniqKey="Sabaiduc S" first="Suzana" last="Sabaiduc">Suzana Sabaiduc</name><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M" last="Skowronski">Danuta M. Skowronski</name><name sortKey="Winter, Anne Luise" sort="Winter, Anne Luise" uniqKey="Winter A" first="Anne-Luise" last="Winter">Anne-Luise Winter</name></noCountry><country name="Canada"><region name="Alberta"><name sortKey="Dickinson, James A" sort="Dickinson, James A" uniqKey="Dickinson J" first="James A" last="Dickinson">James A. Dickinson</name></region><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B" last="Gubbay">Jonathan B. Gubbay</name><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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