Boosting Heterosubtypic Neutralization Antibodies in Recipients of 2009 Pandemic H1N1 Influenza Vaccine
Identifieur interne : 000707 ( Ncbi/Curation ); précédent : 000706; suivant : 000708Boosting Heterosubtypic Neutralization Antibodies in Recipients of 2009 Pandemic H1N1 Influenza Vaccine
Auteurs : Chao Qiu ; Yang Huang [République populaire de Chine] ; Qian Wang [République populaire de Chine] ; Di Tian ; Wanju Zhang ; Yunwen Hu ; Zhenghong Yuan ; Xiaoyan Zhang ; Jianqing XuSource :
- Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America [ 1058-4838 ] ; 2011.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Animaux, Anticorps antiviraux (sang), Anticorps neutralisants (sang), Chine, Femelle, Grippe humaine (), Humains, Immunoglobuline G (sang), Mâle, Souris, Sous-type H1N1 du virus de la grippe A (immunologie), Sous-type H2N2 du virus de la grippe A (immunologie), Sous-type H3N2 du virus de la grippe A (immunologie), Sous-type H5N1 du virus de la grippe A (immunologie), Tests de neutralisation (), Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (immunologie).
- MESH :
- administration et posologie : Vaccins antigrippaux.
- immunologie : Sous-type H1N1 du virus de la grippe A, Sous-type H2N2 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A, Sous-type H5N1 du virus de la grippe A, Vaccins antigrippaux.
- sang : Anticorps antiviraux, Anticorps neutralisants, Immunoglobuline G.
- Adulte, Adulte d'âge moyen, Animaux, Chine, Femelle, Grippe humaine, Humains, Mâle, Souris, Tests de neutralisation.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Adult, Animals, Antibodies, Neutralizing (blood), Antibodies, Viral (blood), China, Female, Humans, Immunoglobulin G (blood), Influenza A Virus, H1N1 Subtype (immunology), Influenza A Virus, H2N2 Subtype (immunology), Influenza A Virus, H3N2 Subtype (immunology), Influenza A Virus, H5N1 Subtype (immunology), Influenza Vaccines (administration & dosage), Influenza Vaccines (immunology), Influenza, Human (prevention & control), Male, Mice, Middle Aged, Neutralization Tests (methods).
- MESH :
- chemical , administration & dosage : Influenza Vaccines.
- chemical , blood : Antibodies, Neutralizing, Antibodies, Viral, Immunoglobulin G.
- chemical , immunology : Influenza Vaccines.
- geographic : China.
- immunology : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H2N2 Subtype, Influenza A Virus, H3N2 Subtype, Influenza A Virus, H5N1 Subtype.
- methods : Neutralization Tests.
- prevention & control : Influenza, Human.
- Adult, Animals, Female, Humans, Male, Mice, Middle Aged.
Abstract
Our data demonstrated that the inoculation with vaccine derived from the 2009 pandemic influenza raised vigorous neutralization antibodies against both cognate H1N1 and heterotypic influenza viruses. This observation has important implication for vaccine development.
Url:
DOI: 10.1093/cid/cir753
PubMed: 22052887
PubMed Central: 3243653
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<front><div type="abstract" xml:lang="en"><p>Our data demonstrated that the inoculation with vaccine derived from the 2009 pandemic influenza raised vigorous neutralization antibodies against both cognate H1N1 and heterotypic influenza viruses. This observation has important implication for vaccine development.</p>
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