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Clinical and morphologic studies on the guinea pig eye infected with human influenza virus strains of different virulence.

Identifieur interne : 002394 ( Main/Merge ); précédent : 002393; suivant : 002395

Clinical and morphologic studies on the guinea pig eye infected with human influenza virus strains of different virulence.

Auteurs : E E Rozina [Russie] ; O E Khudaverdyan ; Ghendon YuZ

Source :

RBID : pubmed:2892383

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English descriptors

Abstract

Human influenza virus serotypes H3N2 and H2N2 caused iridocyclitis and uveitis when inoculated at does of 10(6) 6.5 EID50 into the guinea pig eye anterior chamber. Virulent influenza virus strains and their attenuated variants prepared by passaging in chick embryos (CE) have been compared in this model. These studies showed that virulent viruses cause more severe damage in the eyes than the attenuated strains.

PubMed: 2892383

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pubmed:2892383

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<nlm:affiliation>Moscow Research Institute of Viral Preparations, U.S.S.R. Ministry of Health, Moscow.</nlm:affiliation>
<country>Russie</country>
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<term>Animals</term>
<term>Anterior Chamber (microbiology)</term>
<term>Anterior Chamber (pathology)</term>
<term>Chick Embryo</term>
<term>Eye (microbiology)</term>
<term>Eye (pathology)</term>
<term>Guinea Pigs</term>
<term>Influenza A virus (pathogenicity)</term>
<term>Orthomyxoviridae Infections (microbiology)</term>
<term>Orthomyxoviridae Infections (pathology)</term>
<term>Uveitis (microbiology)</term>
<term>Uveitis (pathology)</term>
<term>Uveitis, Anterior (microbiology)</term>
<term>Uveitis, Anterior (pathology)</term>
<term>Virulence</term>
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<term>Animaux</term>
<term>Chambre antérieure du bulbe oculaire (anatomopathologie)</term>
<term>Chambre antérieure du bulbe oculaire (microbiologie)</term>
<term>Cochons d'Inde</term>
<term>Embryon de poulet</term>
<term>Infections à Orthomyxoviridae (anatomopathologie)</term>
<term>Infections à Orthomyxoviridae (microbiologie)</term>
<term>Oeil (anatomopathologie)</term>
<term>Oeil (microbiologie)</term>
<term>Uvéite (anatomopathologie)</term>
<term>Uvéite (microbiologie)</term>
<term>Uvéite antérieure (anatomopathologie)</term>
<term>Uvéite antérieure (microbiologie)</term>
<term>Virulence</term>
<term>Virus de la grippe A (pathogénicité)</term>
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<term>Chambre antérieure du bulbe oculaire</term>
<term>Infections à Orthomyxoviridae</term>
<term>Oeil</term>
<term>Uvéite</term>
<term>Uvéite antérieure</term>
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<term>Chambre antérieure du bulbe oculaire</term>
<term>Infections à Orthomyxoviridae</term>
<term>Oeil</term>
<term>Uvéite</term>
<term>Uvéite antérieure</term>
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<keywords scheme="MESH" qualifier="microbiology" xml:lang="en">
<term>Anterior Chamber</term>
<term>Eye</term>
<term>Orthomyxoviridae Infections</term>
<term>Uveitis</term>
<term>Uveitis, Anterior</term>
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<term>Virus de la grippe A</term>
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<term>Anterior Chamber</term>
<term>Eye</term>
<term>Orthomyxoviridae Infections</term>
<term>Uveitis</term>
<term>Uveitis, Anterior</term>
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<term>Animals</term>
<term>Chick Embryo</term>
<term>Guinea Pigs</term>
<term>Virulence</term>
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<term>Animaux</term>
<term>Cochons d'Inde</term>
<term>Embryon de poulet</term>
<term>Virulence</term>
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