Clinical and morphologic studies on the guinea pig eye infected with human influenza virus strains of different virulence.
Identifieur interne : 000E11 ( Ncbi/Curation ); précédent : 000E10; suivant : 000E12Clinical and morphologic studies on the guinea pig eye infected with human influenza virus strains of different virulence.
Auteurs : E E Rozina [Russie] ; O E Khudaverdyan ; Ghendon YuZSource :
- Acta virologica [ 0001-723X ] ; 1987.
Descripteurs français
- KwdFr :
- Animaux, Chambre antérieure du bulbe oculaire (anatomopathologie), Chambre antérieure du bulbe oculaire (microbiologie), Cochons d'Inde, Embryon de poulet, Infections à Orthomyxoviridae (anatomopathologie), Infections à Orthomyxoviridae (microbiologie), Oeil (anatomopathologie), Oeil (microbiologie), Uvéite (anatomopathologie), Uvéite (microbiologie), Uvéite antérieure (anatomopathologie), Uvéite antérieure (microbiologie), Virulence, Virus de la grippe A (pathogénicité).
- MESH :
- anatomopathologie : Chambre antérieure du bulbe oculaire, Infections à Orthomyxoviridae, Oeil, Uvéite, Uvéite antérieure.
- microbiologie : Chambre antérieure du bulbe oculaire, Infections à Orthomyxoviridae, Oeil, Uvéite, Uvéite antérieure.
- pathogénicité : Virus de la grippe A.
- Animaux, Cochons d'Inde, Embryon de poulet, Virulence.
English descriptors
- KwdEn :
- Animals, Anterior Chamber (microbiology), Anterior Chamber (pathology), Chick Embryo, Eye (microbiology), Eye (pathology), Guinea Pigs, Influenza A virus (pathogenicity), Orthomyxoviridae Infections (microbiology), Orthomyxoviridae Infections (pathology), Uveitis (microbiology), Uveitis (pathology), Uveitis, Anterior (microbiology), Uveitis, Anterior (pathology), Virulence.
- MESH :
- microbiology : Anterior Chamber, Eye, Orthomyxoviridae Infections, Uveitis, Uveitis, Anterior.
- pathogenicity : Influenza A virus.
- pathology : Anterior Chamber, Eye, Orthomyxoviridae Infections, Uveitis, Uveitis, Anterior.
- Animals, Chick Embryo, Guinea Pigs, Virulence.
Abstract
Human influenza virus serotypes H3N2 and H2N2 caused iridocyclitis and uveitis when inoculated at does of 10(6) 6.5 EID50 into the guinea pig eye anterior chamber. Virulent influenza virus strains and their attenuated variants prepared by passaging in chick embryos (CE) have been compared in this model. These studies showed that virulent viruses cause more severe damage in the eyes than the attenuated strains.
PubMed: 2892383
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pubmed:2892383Le document en format XML
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<country>Russie</country>
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<wicri:orgArea>Moscow Research Institute of Viral Preparations, U.S.S.R. Ministry of Health</wicri:orgArea>
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<series><title level="j">Acta virologica</title>
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<term>Anterior Chamber (microbiology)</term>
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<term>Chick Embryo</term>
<term>Eye (microbiology)</term>
<term>Eye (pathology)</term>
<term>Guinea Pigs</term>
<term>Influenza A virus (pathogenicity)</term>
<term>Orthomyxoviridae Infections (microbiology)</term>
<term>Orthomyxoviridae Infections (pathology)</term>
<term>Uveitis (microbiology)</term>
<term>Uveitis (pathology)</term>
<term>Uveitis, Anterior (microbiology)</term>
<term>Uveitis, Anterior (pathology)</term>
<term>Virulence</term>
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<term>Chambre antérieure du bulbe oculaire (anatomopathologie)</term>
<term>Chambre antérieure du bulbe oculaire (microbiologie)</term>
<term>Cochons d'Inde</term>
<term>Embryon de poulet</term>
<term>Infections à Orthomyxoviridae (anatomopathologie)</term>
<term>Infections à Orthomyxoviridae (microbiologie)</term>
<term>Oeil (anatomopathologie)</term>
<term>Oeil (microbiologie)</term>
<term>Uvéite (anatomopathologie)</term>
<term>Uvéite (microbiologie)</term>
<term>Uvéite antérieure (anatomopathologie)</term>
<term>Uvéite antérieure (microbiologie)</term>
<term>Virulence</term>
<term>Virus de la grippe A (pathogénicité)</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Chambre antérieure du bulbe oculaire</term>
<term>Infections à Orthomyxoviridae</term>
<term>Oeil</term>
<term>Uvéite</term>
<term>Uvéite antérieure</term>
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<term>Infections à Orthomyxoviridae</term>
<term>Oeil</term>
<term>Uvéite</term>
<term>Uvéite antérieure</term>
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<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Anterior Chamber</term>
<term>Eye</term>
<term>Orthomyxoviridae Infections</term>
<term>Uveitis</term>
<term>Uveitis, Anterior</term>
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<term>Eye</term>
<term>Orthomyxoviridae Infections</term>
<term>Uveitis</term>
<term>Uveitis, Anterior</term>
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<term>Chick Embryo</term>
<term>Guinea Pigs</term>
<term>Virulence</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Cochons d'Inde</term>
<term>Embryon de poulet</term>
<term>Virulence</term>
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<front><div type="abstract" xml:lang="en">Human influenza virus serotypes H3N2 and H2N2 caused iridocyclitis and uveitis when inoculated at does of 10(6) 6.5 EID50 into the guinea pig eye anterior chamber. Virulent influenza virus strains and their attenuated variants prepared by passaging in chick embryos (CE) have been compared in this model. These studies showed that virulent viruses cause more severe damage in the eyes than the attenuated strains.</div>
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