Pandemic versus epidemic influenza mortality : A pattern of changing age distribution
Identifieur interne : 001B76 ( Main/Merge ); précédent : 001B75; suivant : 001B77Pandemic versus epidemic influenza mortality : A pattern of changing age distribution
Auteurs : L. Simonsen [États-Unis] ; M. J. Clarke [États-Unis] ; L. B. Schonberger [États-Unis] ; N. H. Arden [États-Unis] ; N. J. Cox [États-Unis] ; K. Fukuda [États-Unis]Source :
- The Journal of infectious diseases [ 0022-1899 ] ; 1998.
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English descriptors
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Abstract
Almost all deaths related to current influenza epidemics occur among the elderly. However, mortality was greatest among the young during the 1918-1919 pandemic. This study compared the age distribution of influenza-related deaths in the United States during this century's three influenza A pandemics with that of the following epidemics. Half of influenza-related deaths during the 1968-1969 influenza A (H3N2) pandemic and large proportions of influenza-related deaths during the 1957-1958 influenza A (H2N2) and the 1918-1919 influenza A (H1N1) pandemics occurred among persons <65 years old. However, this group accounted for decrementally smaller proportions of deaths during the first decade following each pandemic. A model suggested that this mortality pattern may be explained by selective acquisition of protection against fatal illness among younger persons. The large proportion of influenza-related deaths during each pandemic and the following decade among persons <65 years old should be considered in planning for pandemics.
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Pascal:98-0406849Le document en format XML
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<front><div type="abstract" xml:lang="en">Almost all deaths related to current influenza epidemics occur among the elderly. However, mortality was greatest among the young during the 1918-1919 pandemic. This study compared the age distribution of influenza-related deaths in the United States during this century's three influenza A pandemics with that of the following epidemics. Half of influenza-related deaths during the 1968-1969 influenza A (H3N2) pandemic and large proportions of influenza-related deaths during the 1957-1958 influenza A (H2N2) and the 1918-1919 influenza A (H1N1) pandemics occurred among persons <65 years old. However, this group accounted for decrementally smaller proportions of deaths during the first decade following each pandemic. A model suggested that this mortality pattern may be explained by selective acquisition of protection against fatal illness among younger persons. The large proportion of influenza-related deaths during each pandemic and the following decade among persons <65 years old should be considered in planning for pandemics.</div>
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