Genotypic characterization and clinical evaluation of an influenza A/Texas/1/77 (H3N2)-like recombinant: RIT 4199
Identifieur interne : 000C14 ( Istex/Corpus ); précédent : 000C13; suivant : 000C15Genotypic characterization and clinical evaluation of an influenza A/Texas/1/77 (H3N2)-like recombinant: RIT 4199
Auteurs : G. Florent ; A. Hay ; M. Lobmann ; D. Jovanovic ; A. DalemSource :
- Journal of Biological Standardization [ 0092-1157 ] ; 1979.
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Abstract
The RIT 4199 (H2N2) strain was obtained by recombination of PR/8/34 (H0N1) and A/Alaska/5/77 (H2N2) isolates. Its genetic composition was determined by RNA-RNA hybridization and by identification by gel electrophoresis of the double-stranded RNA formed.The RIT 4199 was inoculated intranasally to 27 seronegative volunteers at a dose of 107−3 EID50. The results show that it is suitable for live vaccine strain.
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DOI: 10.1016/S0092-1157(79)80010-4
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ISTEX:A8F949B7362717F9214900A62A1DC643E1BC7BBBLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genotypic characterization and clinical evaluation of an influenza A/Texas/1/77 (H3N2)-like recombinant: RIT 4199</title><author><name sortKey="Florent, G" sort="Florent, G" uniqKey="Florent G" first="G." last="Florent">G. Florent</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author><author><name sortKey="Hay, A" sort="Hay, A" uniqKey="Hay A" first="A." last="Hay">A. Hay</name><affiliation><mods:affiliation>Division of Virology, National Institute for Medical Research, Mill Hill, London NW7, England</mods:affiliation></affiliation></author><author><name sortKey="Lobmann, M" sort="Lobmann, M" uniqKey="Lobmann M" first="M." last="Lobmann">M. Lobmann</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author><author><name sortKey="Jovanovic, D" sort="Jovanovic, D" uniqKey="Jovanovic D" first="D." last="Jovanovic">D. Jovanovic</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author><author><name sortKey="Dalem, A" sort="Dalem, A" uniqKey="Dalem A" first="A." last="Dalem">A. Dalem</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A8F949B7362717F9214900A62A1DC643E1BC7BBB</idno><date when="1979" year="1979">1979</date><idno type="doi">10.1016/S0092-1157(79)80010-4</idno><idno type="url">https://api.istex.fr/ark:/67375/6H6-1X52D3H2-G/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000C14</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000C14</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Genotypic characterization and clinical evaluation of an influenza A/Texas/1/77 (H3N2)-like recombinant: RIT 4199</title><author><name sortKey="Florent, G" sort="Florent, G" uniqKey="Florent G" first="G." last="Florent">G. Florent</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author><author><name sortKey="Hay, A" sort="Hay, A" uniqKey="Hay A" first="A." last="Hay">A. Hay</name><affiliation><mods:affiliation>Division of Virology, National Institute for Medical Research, Mill Hill, London NW7, England</mods:affiliation></affiliation></author><author><name sortKey="Lobmann, M" sort="Lobmann, M" uniqKey="Lobmann M" first="M." last="Lobmann">M. Lobmann</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author><author><name sortKey="Jovanovic, D" sort="Jovanovic, D" uniqKey="Jovanovic D" first="D." last="Jovanovic">D. Jovanovic</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author><author><name sortKey="Dalem, A" sort="Dalem, A" uniqKey="Dalem A" first="A." last="Dalem">A. Dalem</name><affiliation><mods:affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Biological Standardization</title><title level="j" type="abbrev">JBSTD</title><idno type="ISSN">0092-1157</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1979">1979</date><biblScope unit="volume">7</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="361">361</biblScope><biblScope unit="page" to="368">368</biblScope></imprint><idno type="ISSN">0092-1157</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0092-1157</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>First group</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The RIT 4199 (H2N2) strain was obtained by recombination of PR/8/34 (H0N1) and A/Alaska/5/77 (H2N2) isolates. Its genetic composition was determined by RNA-RNA hybridization and by identification by gel electrophoresis of the double-stranded RNA formed.The RIT 4199 was inoculated intranasally to 27 seronegative volunteers at a dose of 107−3 EID50. The results show that it is suitable for live vaccine strain.</div></front></TEI><istex><corpusName>elsevier</corpusName><keywords><teeft><json:string>first group</json:string></teeft></keywords><author><json:item><name>G. Florent</name><affiliations><json:string>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</json:string></affiliations></json:item><json:item><name>A. Hay</name><affiliations><json:string>Division of Virology, National Institute for Medical Research, Mill Hill, London NW7, England</json:string></affiliations></json:item><json:item><name>M. Lobmann</name><affiliations><json:string>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</json:string></affiliations></json:item><json:item><name>D. Jovanovic</name><affiliations><json:string>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</json:string></affiliations></json:item><json:item><name>A. Dalem</name><affiliations><json:string>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</json:string></affiliations></json:item></author><articleId><json:string>79800104</json:string></articleId><arkIstex>ark:/67375/6H6-1X52D3H2-G</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>The RIT 4199 (H2N2) strain was obtained by recombination of PR/8/34 (H0N1) and A/Alaska/5/77 (H2N2) isolates. Its genetic composition was determined by RNA-RNA hybridization and by identification by gel electrophoresis of the double-stranded RNA formed.The RIT 4199 was inoculated intranasally to 27 seronegative volunteers at a dose of 107−3 EID50. 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Its genetic composition was determined by RNA-RNA hybridization and by identification by gel electrophoresis of the double-stranded RNA formed.The RIT 4199 was inoculated intranasally to 27 seronegative volunteers at a dose of 107−3 EID50. The results show that it is suitable for live vaccine strain.</p></abstract></profileDesc><revisionDesc><change when="1979">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-1X52D3H2-G/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier doc found" wicri:toSee="Elsevier, no converted or simple article"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 5.0.1//EN//XML" URI="art501.dtd" name="istex:docType"></istex:docType><istex:document><article version="5.0" xml:lang="en" docsubtype="fla"><item-info><jid>JBSTD</jid><aid>79800104</aid><ce:pii>S0092-1157(79)80010-4</ce:pii><ce:doi>10.1016/S0092-1157(79)80010-4</ce:doi><ce:copyright type="unknown" year="1979">The International Association of Biological Standardization</ce:copyright></item-info><head><ce:article-footnote><ce:label>*</ce:label><ce:note-para>Part of this study was supported by a grant from the Institut pour l'Encouragement de la Recherche Scientifique dans l'Industrie et l'Agriculture (I.R.S.I.A.).</ce:note-para></ce:article-footnote><ce:title>Genotypic characterization and clinical evaluation of an influenza A/Texas/1/77 (H<ce:inf loc="post">3</ce:inf>N<ce:inf loc="post">2</ce:inf>)-like recombinant: RIT 4199</ce:title><ce:author-group><ce:author><ce:given-name>G.</ce:given-name><ce:surname>Florent</ce:surname><ce:cross-ref refid="aff1">†</ce:cross-ref></ce:author><ce:author><ce:given-name>A.</ce:given-name><ce:surname>Hay</ce:surname><ce:cross-ref refid="aff2">‡</ce:cross-ref></ce:author><ce:author><ce:given-name>M.</ce:given-name><ce:surname>Lobmann</ce:surname><ce:cross-ref refid="aff1">†</ce:cross-ref></ce:author><ce:author><ce:given-name>D.</ce:given-name><ce:surname>Jovanovic</ce:surname><ce:cross-ref refid="aff1">†</ce:cross-ref></ce:author><ce:author><ce:given-name>A.</ce:given-name><ce:surname>Dalem</ce:surname><ce:cross-ref refid="aff1">†</ce:cross-ref></ce:author><ce:affiliation id="aff1"><ce:label>†</ce:label><ce:textfn>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</ce:textfn></ce:affiliation><ce:affiliation id="aff2"><ce:label>‡</ce:label><ce:textfn>Division of Virology, National Institute for Medical Research, Mill Hill, London NW7, England</ce:textfn></ce:affiliation></ce:author-group><ce:date-received day="16" month="3" year="1979"></ce:date-received><ce:abstract id="ab1" class="author" xml:lang="en"><ce:abstract-sec><ce:simple-para>The RIT 4199 (H<ce:inf loc="post">2</ce:inf>N<ce:inf loc="post">2</ce:inf>) strain was obtained by recombination of PR/8/34 (H<ce:inf loc="post">0</ce:inf>N<ce:inf loc="post">1</ce:inf>) and A/Alaska/5/77 (H<ce:inf loc="post">2</ce:inf>N<ce:inf loc="post">2</ce:inf>) isolates. Its genetic composition was determined by RNA-RNA hybridization and by identification by gel electrophoresis of the double-stranded RNA formed.</ce:simple-para><ce:simple-para>The RIT 4199 was inoculated intranasally to 27 seronegative volunteers at a dose of 10<ce:sup loc="post">7−3</ce:sup> EID<ce:inf loc="post">50</ce:inf>. The results show that it is suitable for live vaccine strain.</ce:simple-para></ce:abstract-sec></ce:abstract></head><tail><ce:bibliography><ce:section-title>References</ce:section-title><ce:bibliography-sec><ce:bib-reference id="bib1"><ce:label>Beare, 1975</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Beare</ce:surname><ce:given-name>A.S.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Live viruses for immunization against influenza</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Progress of Medical Virology</sb:maintitle></sb:title><sb:volume-nr>20</sb:volume-nr></sb:series><sb:date>1975</sb:date></sb:issue><sb:pages><sb:first-page>49</sb:first-page><sb:last-page>83</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib2"><ce:label>Beare and Hall, 1971</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Beare</ce:surname><ce:given-name>A.S.</ce:given-name></sb:author><sb:author><ce:surname>Hall</ce:surname><ce:given-name>T.S.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Recombinant influenza A viruses as live vaccines for man</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Lancet</sb:maintitle></sb:title><sb:volume-nr>ii</sb:volume-nr></sb:series><sb:date>1971</sb:date></sb:issue><sb:pages><sb:first-page>1271</sb:first-page><sb:last-page>1273</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib3"><ce:label>Beare, et al, 1975</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Beare</ce:surname><ce:given-name>A.S.</ce:given-name></sb:author><sb:author><ce:surname>Schild</ce:surname><ce:given-name>G.C.</ce:given-name></sb:author><sb:author><ce:surname>Craig</ce:surname><ce:given-name>J.W.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Trials in man with live recombinants made from A/PR/8/34 (H<ce:inf loc="post">0</ce:inf>N<ce:inf loc="post">1</ce:inf>) and wild H<ce:inf loc="post">3</ce:inf>N<ce:inf loc="post">2</ce:inf> influenza viruses</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Lancet</sb:maintitle></sb:title><sb:volume-nr>ii</sb:volume-nr></sb:series><sb:date>1975</sb:date></sb:issue><sb:pages><sb:first-page>729</sb:first-page><sb:last-page>732</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib4"><ce:label>Callow and Beare, 1976</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Callow</ce:surname><ce:given-name>K.A.</ce:given-name></sb:author><sb:author><ce:surname>Beare</ce:surname><ce:given-name>A.S.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Measurement of antibody to influenza virus neuraminidase by single radial hemolysis in agarose gels</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Infection and Immunity</sb:maintitle></sb:title><sb:volume-nr>13</sb:volume-nr></sb:series><sb:date>1976</sb:date></sb:issue><sb:pages><sb:first-page>1</sb:first-page><sb:last-page>8</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib5"><ce:label>Delem and Jovanovic, 1978</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Delem</ce:surname><ce:given-name>A.</ce:given-name></sb:author><sb:author><ce:surname>Jovanovic</ce:surname><ce:given-name>D.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Correlation between rate of infection and pre-existing titer of serum antibody as determined by single radial hemolysis during an epidemic of influenza A/Victoria/3/75</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Journal of Infectious Diseases</sb:maintitle></sb:title><sb:volume-nr>137</sb:volume-nr></sb:series><sb:date>1978</sb:date></sb:issue><sb:pages><sb:first-page>194</sb:first-page><sb:last-page>196</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib6"><ce:label>Douglas and Betts, 1978</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Douglas</ce:surname><ce:given-name>R.G.</ce:given-name></sb:author><sb:author><ce:surname>Betts</ce:surname><ce:given-name>R.F.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Studies with live attenuated influenza vaccines</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>American Journal of Clinical Pathology</sb:maintitle></sb:title><sb:volume-nr>70</sb:volume-nr></sb:series><sb:issue-nr>suppl. 1</sb:issue-nr><sb:date>1978</sb:date></sb:issue><sb:pages><sb:first-page>153</sb:first-page><sb:last-page>158</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib7"><ce:label>Florent, 1977</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Florent</ce:surname><ce:given-name>G.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>RNA-RNA hybridation between influenza viruses</sb:maintitle></sb:title></sb:contribution><sb:host><sb:edited-book><sb:book-series><sb:series><sb:title><sb:maintitle>Development in Biological Standardization</sb:maintitle></sb:title><sb:volume-nr>Vol. 39</sb:volume-nr></sb:series></sb:book-series><sb:date>1977</sb:date><sb:publisher><sb:name>Karger</sb:name><sb:location>Basel</sb:location></sb:publisher></sb:edited-book><sb:pages><sb:first-page>11</sb:first-page><sb:last-page>14</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib8"><ce:label>Florent, et al, 1977</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Florent</ce:surname><ce:given-name>G.</ce:given-name></sb:author><sb:author><ce:surname>Lobmann</ce:surname><ce:given-name>M.</ce:given-name></sb:author><sb:author><ce:surname>Beare</ce:surname><ce:given-name>A.S.</ce:given-name></sb:author><sb:author><ce:surname>Zygraich</ce:surname><ce:given-name>N.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>RNAs of influenza virus recombinants derived from parents of known virulence for man</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Archives of Virology</sb:maintitle></sb:title><sb:volume-nr>54</sb:volume-nr></sb:series><sb:date>1977</sb:date></sb:issue><sb:pages><sb:first-page>19</sb:first-page><sb:last-page>28</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib9"><ce:label>Hay, et al, 1977</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Hay</ce:surname><ce:given-name>A.J.</ce:given-name></sb:author><sb:author><ce:surname>Lomniczi</ce:surname><ce:given-name>B.</ce:given-name></sb:author><sb:author><ce:surname>Bellamy</ce:surname><ce:given-name>A.R.</ce:given-name></sb:author><sb:author><ce:surname>Skehel</ce:surname><ce:given-name>J.J.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Transcription of the influenza virus genome</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Virology</sb:maintitle></sb:title><sb:volume-nr>83</sb:volume-nr></sb:series><sb:date>1977</sb:date></sb:issue><sb:pages><sb:first-page>337</sb:first-page><sb:last-page>355</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib10"><ce:label>Lobmann, et al, 1977</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Lobmann</ce:surname><ce:given-name>M.</ce:given-name></sb:author><sb:author><ce:surname>Delem</ce:surname><ce:given-name>A.</ce:given-name></sb:author><sb:author><ce:surname>Jovanovic</ce:surname><ce:given-name>D.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Properties of A/Victoria/3/75 recombinants: development of an attenuated strain RIT 4050</sb:maintitle></sb:title></sb:contribution><sb:host><sb:edited-book><sb:book-series><sb:series><sb:title><sb:maintitle>Development in Biological Standardization</sb:maintitle></sb:title><sb:volume-nr>Vol. 39</sb:volume-nr></sb:series></sb:book-series><sb:date>1977</sb:date><sb:publisher><sb:name>Karger</sb:name><sb:location>Basel</sb:location></sb:publisher></sb:edited-book><sb:pages><sb:first-page>43</sb:first-page><sb:last-page>46</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib11"><ce:label>Palese, 1977</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Palese</ce:surname><ce:given-name>P.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>The genes of influenza virus</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Cell</sb:maintitle></sb:title><sb:volume-nr>10</sb:volume-nr></sb:series><sb:date>1977</sb:date></sb:issue><sb:pages><sb:first-page>1</sb:first-page><sb:last-page>10</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib12"><ce:label>Scholtissek, et al, 1976</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Scholtissek</ce:surname><ce:given-name>C.</ce:given-name></sb:author><sb:author><ce:surname>Harms</ce:surname><ce:given-name>E.</ce:given-name></sb:author><sb:author><ce:surname>Rodhe</ce:surname><ce:given-name>W.</ce:given-name></sb:author><sb:author><ce:surname>Orlich</ce:surname><ce:given-name>M.</ce:given-name></sb:author><sb:author><ce:surname>Rott</ce:surname><ce:given-name>R.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Correlation between RNA fragments of fowl plague virus and their corresponding gene functions</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Virology</sb:maintitle></sb:title><sb:volume-nr>74</sb:volume-nr></sb:series><sb:date>1976</sb:date></sb:issue><sb:pages><sb:first-page>332</sb:first-page><sb:last-page>344</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib13"><ce:label>Scholtissek and Rott, 1969a</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Scholtissek</ce:surname><ce:given-name>C.</ce:given-name></sb:author><sb:author><ce:surname>Rott</ce:surname><ce:given-name>R.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Ribonucleic acid nucleotidyl transferase induced in chick fibroblast after infection with an influenza virus</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Journal of General Virology</sb:maintitle></sb:title><sb:volume-nr>4</sb:volume-nr></sb:series><sb:date>1969</sb:date></sb:issue><sb:pages><sb:first-page>125</sb:first-page><sb:last-page>137</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib14"><ce:label>Scholtissek and Rott, 1969b</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Scholtissek</ce:surname><ce:given-name>C.</ce:given-name></sb:author><sb:author><ce:surname>Rott</ce:surname><ce:given-name>R.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Hybridization studies with influenza virus RNA</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Virology</sb:maintitle></sb:title><sb:volume-nr>39</sb:volume-nr></sb:series><sb:date>1969</sb:date></sb:issue><sb:pages><sb:first-page>400</sb:first-page><sb:last-page>407</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib15"><ce:label>Scholtissek, et al, 1977</ce:label><sb:reference><sb:contribution langtype="en"><sb:authors><sb:author><ce:surname>Scholtissek</ce:surname><ce:given-name>C.</ce:given-name></sb:author><sb:author><ce:surname>Rott</ce:surname><ce:given-name>R.</ce:given-name></sb:author><sb:author><ce:surname>Orlich</ce:surname><ce:given-name>M.</ce:given-name></sb:author><sb:author><ce:surname>Harms</ce:surname><ce:given-name>E.</ce:given-name></sb:author><sb:author><ce:surname>Rhode</ce:surname><ce:given-name>W.</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Correlation of pathogenicity and gene constellation of an influenza A virus (Fowl plague) 1. Exchange of a single gene</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Virology</sb:maintitle></sb:title><sb:volume-nr>81</sb:volume-nr></sb:series><sb:date>1977</sb:date></sb:issue><sb:pages><sb:first-page>74</sb:first-page><sb:last-page>80</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference></ce:bibliography-sec></ce:bibliography></tail></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Genotypic characterization and clinical evaluation of an influenza A/Texas/1/77 (H3N2)-like recombinant: RIT 4199</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Genotypic characterization and clinical evaluation of an influenza A/Texas/1/77 (H</title></titleInfo><name type="personal"><namePart type="given">G.</namePart><namePart type="family">Florent</namePart><affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Hay</namePart><affiliation>Division of Virology, National Institute for Medical Research, Mill Hill, London NW7, England</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Lobmann</namePart><affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Jovanovic</namePart><affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Dalem</namePart><affiliation>Immuno-Biology Department and Clinical Research Department, Smith Kline-RIT, 1330 Rixensart, Belgium</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1979</dateIssued><copyrightDate encoding="w3cdtf">1979</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">The RIT 4199 (H2N2) strain was obtained by recombination of PR/8/34 (H0N1) and A/Alaska/5/77 (H2N2) isolates. Its genetic composition was determined by RNA-RNA hybridization and by identification by gel electrophoresis of the double-stranded RNA formed.The RIT 4199 was inoculated intranasally to 27 seronegative volunteers at a dose of 107−3 EID50. The results show that it is suitable for live vaccine strain.</abstract><note>Part of this study was supported by a grant from the Institut pour l'Encouragement de la Recherche Scientifique dans l'Industrie et l'Agriculture (I.R.S.I.A.).</note><relatedItem type="host"><titleInfo><title>Journal of Biological Standardization</title></titleInfo><titleInfo type="abbreviated"><title>JBSTD</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1979</dateIssued></originInfo><identifier type="ISSN">0092-1157</identifier><identifier type="PII">S0092-1157(79)X8001-8</identifier><part><date>1979</date><detail type="volume"><number>7</number><caption>vol.</caption></detail><detail type="issue"><number>4</number><caption>no.</caption></detail><extent unit="issue-pages"><start>275</start><end>407</end></extent><extent unit="pages"><start>361</start><end>368</end></extent></part></relatedItem><identifier type="istex">A8F949B7362717F9214900A62A1DC643E1BC7BBB</identifier><identifier type="ark">ark:/67375/6H6-1X52D3H2-G</identifier><identifier type="DOI">10.1016/S0092-1157(79)80010-4</identifier><identifier type="PII">S0092-1157(79)80010-4</identifier><identifier type="ArticleID">79800104</identifier><accessCondition type="use and reproduction" contentType="copyright">©1979 The International Association of Biological Standardization</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</recordContentSource><recordOrigin>The International Association of Biological Standardization, ©1979</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-1X52D3H2-G/record.json</uri></json:item></metadata></istex></record>Pour manipuler ce document sous Unix (Dilib)
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