Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses
Identifieur interne : 000187 ( Istex/Corpus ); précédent : 000186; suivant : 000188Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses
Auteurs : S. Ludwig ; U. Schultz ; J. Mandler ; W. M. Fitch ; C. ScholtissekSource :
- Virology [ 0042-6822 ] ; 1991.
English descriptors
- Teeft :
- Additional selection pressure, Amino, Amino acid replacements, Amino acid sequences, Amino acids, Avian, Avian influenza viruses, Avian strains, Branch point, Buonagurio, Common ancestor, Correlation factor, Eurasian strains, Evolutionary trees, Fitch, Gammelin, Gene, Gene products, Gene tree, Genetic relatedness, Human influenza, Human strains, Influenza, Influenza virus, Influenza viruses, Krystal, Mandler, Mrna, Nakajima, Nonstructural, Nonstructural proteins, Nucleic acids, Nucleoprotein, Nucleotide, Nucleotide sequence, Nucleotide substitutions, Other strains, Palese, Phylogenetic, Phylogenetic tree, Polymerase, Scholtissek, Selection pressure, Side branch, Substitution, Subtypes, Time axis, Treanor, Viral, Virology, Virus.
Abstract
Abstract: Phylogenetic trees were constructed using 38 sequences of the A group and 10 sequences of the B group of the NS gene of influenza A viruses. Within the A group we found avian as well as mammalian influenza A viruses, while within the B group exclusively avian strains were found. The avian and human NS genes of the A group were derived from a common ancestor existing at about 1912. At 13 positions of the amino acid sequences of the NS1 protein two subtypes of the A group can be differentiated, a human and a non-human subtype. Starting at the time of the introduction of an avian PB1 gene into human strains during the antigenic shift at 1957 the NS1 protein of the human strains came under an enhanced selection pressure which might indicate a cooperation of the NS1 protein with and adaptation of the NS1 protein on the newly introduced PB1 gene. Such a selection pressure on the NS2 protein is completely missing. Comparison of all sequences of the NS1 protein revealed four highly conserved regions within the amino-terminal half of the molecule. One of this regions seems to contain the nuclear migration signal. The carboxy-terminal half is completely variable and seems to be dispensable.
Url:
DOI: 10.1016/0042-6822(91)90985-K
Links to Exploration step
ISTEX:1A5F590BF5C538B49002D72B94CCE126AABD3E20Le document en format XML
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Ludwig</name><affiliation><mods:affiliation>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schultz, U" sort="Schultz, U" uniqKey="Schultz U" first="U." last="Schultz">U. Schultz</name><affiliation><mods:affiliation>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Mandler, J" sort="Mandler, J" uniqKey="Mandler J" first="J." last="Mandler">J. Mandler</name><affiliation><mods:affiliation>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Fitch, W M" sort="Fitch, W M" uniqKey="Fitch W" first="W. M." last="Fitch">W. M. 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Within the A group we found avian as well as mammalian influenza A viruses, while within the B group exclusively avian strains were found. The avian and human NS genes of the A group were derived from a common ancestor existing at about 1912. At 13 positions of the amino acid sequences of the NS1 protein two subtypes of the A group can be differentiated, a human and a non-human subtype. Starting at the time of the introduction of an avian PB1 gene into human strains during the antigenic shift at 1957 the NS1 protein of the human strains came under an enhanced selection pressure which might indicate a cooperation of the NS1 protein with and adaptation of the NS1 protein on the newly introduced PB1 gene. Such a selection pressure on the NS2 protein is completely missing. Comparison of all sequences of the NS1 protein revealed four highly conserved regions within the amino-terminal half of the molecule. One of this regions seems to contain the nuclear migration signal. 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Ludwig</name><affiliations><json:string>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</json:string></affiliations></json:item><json:item><name>U. Schultz</name><affiliations><json:string>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</json:string></affiliations></json:item><json:item><name>J. Mandler</name><affiliations><json:string>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</json:string></affiliations></json:item><json:item><name>W.M. Fitch</name><affiliations><json:string>Department of Ecology and Evolutionary Biology, University of California, Irvine, California 92717, USA</json:string></affiliations></json:item><json:item><name>C. Scholtissek</name><affiliations><json:string>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</json:string></affiliations></json:item></author><arkIstex>ark:/67375/6H6-JQW6XFQ5-B</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>Abstract: Phylogenetic trees were constructed using 38 sequences of the A group and 10 sequences of the B group of the NS gene of influenza A viruses. Within the A group we found avian as well as mammalian influenza A viruses, while within the B group exclusively avian strains were found. The avian and human NS genes of the A group were derived from a common ancestor existing at about 1912. At 13 positions of the amino acid sequences of the NS1 protein two subtypes of the A group can be differentiated, a human and a non-human subtype. Starting at the time of the introduction of an avian PB1 gene into human strains during the antigenic shift at 1957 the NS1 protein of the human strains came under an enhanced selection pressure which might indicate a cooperation of the NS1 protein with and adaptation of the NS1 protein on the newly introduced PB1 gene. Such a selection pressure on the NS2 protein is completely missing. Comparison of all sequences of the NS1 protein revealed four highly conserved regions within the amino-terminal half of the molecule. One of this regions seems to contain the nuclear migration signal. The carboxy-terminal half is completely variable and seems to be dispensable.</abstract><qualityIndicators><refBibsNative>true</refBibsNative><abstractWordCount>207</abstractWordCount><abstractCharCount>1209</abstractCharCount><keywordCount>0</keywordCount><score>9.337</score><pdfWordCount>4853</pdfWordCount><pdfCharCount>35185</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>12</pdfPageCount><pdfPageSize>612.28 x 828 pts</pdfPageSize></qualityIndicators><title>Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses</title><pmid><json:string>1830182</json:string></pmid><pii><json:string>0042-6822(91)90985-K</json:string></pii><genre><json:string>research-article</json:string></genre><serie><title>Proc. Natl. Acad. Sci. 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Ludwig et al.</json:string><json:string>Norton et al., 1987</json:string><json:string>Scholtissek and von HoyningenHuene, 1980</json:string><json:string>Scholtissek et al</json:string><json:string>Nakajima et al</json:string><json:string>Petrov et al., 1977</json:string><json:string>Krystal et al., 1983</json:string><json:string>Alting-Mees and Short, 1989</json:string><json:string>Odagiri and Tobita, 1990</json:string><json:string>Altmllller et al., 1989</json:string><json:string>Hatada et al., 1990</json:string><json:string>Baez et al., 1981</json:string><json:string>Porter et al., 1980</json:string><json:string>Mandler et al., 1990</json:string><json:string>Buonagurio et al., 1986</json:string><json:string>Fitch and Farris (1974)</json:string><json:string>Maniatis et al., 1982</json:string><json:string>Fitch et al., 1991</json:string><json:string>Scholtissek and von Hoyningen-Huene, 1980</json:string><json:string>Lamb and Lai, 1980</json:string><json:string>Gammelin et al., 1990</json:string><json:string>Buonaguiro, 1986</json:string><json:string>Nakajima et al., 1990b</json:string><json:string>Koennecke et al.</json:string><json:string>Nakajima et al., 1987</json:string><json:string>von Hoyningen-Huene and Scholtissek, 1983</json:string><json:string>Gammelin et al., 1989</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/6H6-JQW6XFQ5-B</json:string></ark><categories><wos><json:string>1 - 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Within the A group we found avian as well as mammalian influenza A viruses, while within the B group exclusively avian strains were found. The avian and human NS genes of the A group were derived from a common ancestor existing at about 1912. At 13 positions of the amino acid sequences of the NS1 protein two subtypes of the A group can be differentiated, a human and a non-human subtype. Starting at the time of the introduction of an avian PB1 gene into human strains during the antigenic shift at 1957 the NS1 protein of the human strains came under an enhanced selection pressure which might indicate a cooperation of the NS1 protein with and adaptation of the NS1 protein on the newly introduced PB1 gene. Such a selection pressure on the NS2 protein is completely missing. Comparison of all sequences of the NS1 protein revealed four highly conserved regions within the amino-terminal half of the molecule. One of this regions seems to contain the nuclear migration signal. The carboxy-terminal half is completely variable and seems to be dispensable.</p></abstract></profileDesc><revisionDesc><change when="1991">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-JQW6XFQ5-B/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>YVIRO</jid><aid>9190985K</aid><ce:pii>0042-6822(91)90985-K</ce:pii><ce:doi>10.1016/0042-6822(91)90985-K</ce:doi><ce:copyright type="unknown" year="1991"></ce:copyright></item-info><head><ce:title>Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses</ce:title><ce:author-group><ce:author><ce:given-name>S.</ce:given-name><ce:surname>Ludwig</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>U.</ce:given-name><ce:surname>Schultz</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>J.</ce:given-name><ce:surname>Mandler</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>W.M.</ce:given-name><ce:surname>Fitch</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>†</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>C.</ce:given-name><ce:surname>Scholtissek</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>∗</ce:label><ce:textfn>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>†</ce:label><ce:textfn>Department of Ecology and Evolutionary Biology, University of California, Irvine, California 92717, USA</ce:textfn></ce:affiliation></ce:author-group><ce:date-received day="13" month="11" year="1990"></ce:date-received><ce:date-accepted day="16" month="4" year="1991"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Phylogenetic trees were constructed using 38 sequences of the A group and 10 sequences of the B group of the NS gene of influenza A viruses. Within the A group we found avian as well as mammalian influenza A viruses, while within the B group exclusively avian strains were found. The avian and human NS genes of the A group were derived from a common ancestor existing at about 1912. At 13 positions of the amino acid sequences of the NS1 protein two subtypes of the A group can be differentiated, a human and a non-human subtype. Starting at the time of the introduction of an avian PB1 gene into human strains during the antigenic shift at 1957 the NS1 protein of the human strains came under an enhanced selection pressure which might indicate a cooperation of the NS1 protein with and adaptation of the NS1 protein on the newly introduced PB1 gene. Such a selection pressure on the NS2 protein is completely missing. Comparison of all sequences of the NS1 protein revealed four highly conserved regions within the amino-terminal half of the molecule. One of this regions seems to contain the nuclear migration signal. The carboxy-terminal half is completely variable and seems to be dispensable.</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses</title></titleInfo><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Ludwig</namePart><affiliation>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">U.</namePart><namePart type="family">Schultz</namePart><affiliation>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J.</namePart><namePart type="family">Mandler</namePart><affiliation>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W.M.</namePart><namePart type="family">Fitch</namePart><affiliation>Department of Ecology and Evolutionary Biology, University of California, Irvine, California 92717, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Scholtissek</namePart><affiliation>Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1991</dateIssued><copyrightDate encoding="w3cdtf">1991</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">Abstract: Phylogenetic trees were constructed using 38 sequences of the A group and 10 sequences of the B group of the NS gene of influenza A viruses. Within the A group we found avian as well as mammalian influenza A viruses, while within the B group exclusively avian strains were found. The avian and human NS genes of the A group were derived from a common ancestor existing at about 1912. At 13 positions of the amino acid sequences of the NS1 protein two subtypes of the A group can be differentiated, a human and a non-human subtype. Starting at the time of the introduction of an avian PB1 gene into human strains during the antigenic shift at 1957 the NS1 protein of the human strains came under an enhanced selection pressure which might indicate a cooperation of the NS1 protein with and adaptation of the NS1 protein on the newly introduced PB1 gene. Such a selection pressure on the NS2 protein is completely missing. Comparison of all sequences of the NS1 protein revealed four highly conserved regions within the amino-terminal half of the molecule. One of this regions seems to contain the nuclear migration signal. The carboxy-terminal half is completely variable and seems to be dispensable.</abstract><relatedItem type="host"><titleInfo><title>Virology</title></titleInfo><titleInfo type="abbreviated"><title>YVIRO</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1991</dateIssued></originInfo><identifier type="ISSN">0042-6822</identifier><identifier type="PII">S0042-6822(00)X0704-0</identifier><part><date>1991</date><detail type="volume"><number>183</number><caption>vol.</caption></detail><detail type="issue"><number>2</number><caption>no.</caption></detail><extent unit="issue-pages"><start>449</start><end>856</end></extent><extent unit="pages"><start>566</start><end>577</end></extent></part></relatedItem><identifier type="istex">1A5F590BF5C538B49002D72B94CCE126AABD3E20</identifier><identifier type="ark">ark:/67375/6H6-JQW6XFQ5-B</identifier><identifier type="DOI">10.1016/0042-6822(91)90985-K</identifier><identifier type="PII">0042-6822(91)90985-K</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</recordContentSource></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-JQW6XFQ5-B/record.json</uri></json:item></metadata></istex></record>Pour manipuler ce document sous Unix (Dilib)
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