Histological observations on biopsies harvested following sinus floor elevation using a bioactive glass material of narrow size range.
Identifieur interne : 002D22 ( PubMed/Checkpoint ); précédent : 002D21; suivant : 002D23Histological observations on biopsies harvested following sinus floor elevation using a bioactive glass material of narrow size range.
Auteurs : E S Tadjoedin [Pays-Bas] ; G L De Lange ; P J Holzmann ; L. Kulper ; E H BurgerSource :
- Clinical oral implants research [ 0905-7161 ] ; 2000.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Biopsie, Colorants fluorescents, Femelle, Humains, Implant résorbable, Implants dentaires, Matériaux biocompatibles (), Matériaux biocompatibles (usage thérapeutique), Maxillaire (), Mâchoire édentée (), Ostéocytes (anatomopathologie), Ostéogenèse (physiologie), Pose d'implant dentaire endo-osseux, Remodelage osseux (physiologie), Résorption osseuse (anatomopathologie), Sinus maxillaire (), Sinus maxillaire (anatomopathologie), Substituts osseux (), Substituts osseux (usage thérapeutique), Trame osseuse (anatomopathologie), Transplantation osseuse (), Tétracycline, Verre (), Études de suivi.
- MESH :
- anatomopathologie : Ostéocytes, Résorption osseuse, Sinus maxillaire, Trame osseuse.
- physiologie : Ostéogenèse, Remodelage osseux.
- usage thérapeutique : Matériaux biocompatibles, Substituts osseux.
- Adulte d'âge moyen, Biopsie, Colorants fluorescents, Femelle, Humains, Implant résorbable, Implants dentaires, Matériaux biocompatibles, Maxillaire, Mâchoire édentée, Pose d'implant dentaire endo-osseux, Sinus maxillaire, Substituts osseux, Transplantation osseuse, Tétracycline, Verre, Études de suivi.
English descriptors
- KwdEn :
- Absorbable Implants, Biocompatible Materials (chemistry), Biocompatible Materials (therapeutic use), Biopsy, Bone Matrix (pathology), Bone Remodeling (physiology), Bone Resorption (pathology), Bone Substitutes (chemistry), Bone Substitutes (therapeutic use), Bone Transplantation (methods), Dental Implantation, Endosseous, Dental Implants, Female, Fluorescent Dyes, Follow-Up Studies, Glass (chemistry), Humans, Jaw, Edentulous (surgery), Maxilla (surgery), Maxillary Sinus (pathology), Maxillary Sinus (surgery), Middle Aged, Osteocytes (pathology), Osteogenesis (physiology), Tetracycline.
- MESH :
- chemical , chemistry : Biocompatible Materials, Bone Substitutes.
- chemical , therapeutic use : Biocompatible Materials, Bone Substitutes.
- chemistry : Glass.
- methods : Bone Transplantation.
- pathology : Bone Matrix, Bone Resorption, Maxillary Sinus, Osteocytes.
- physiology : Bone Remodeling, Osteogenesis.
- surgery : Jaw, Edentulous, Maxilla, Maxillary Sinus.
- Absorbable Implants, Biopsy, Dental Implantation, Endosseous, Dental Implants, Female, Fluorescent Dyes, Follow-Up Studies, Humans, Middle Aged, Tetracycline.
Abstract
We evaluated the bone augmenting capacity of bioactive glass particles, size range 300-355 microns (BG-particles), in human sinus floor elevations using histomorphometrical methods. A total of 10 patients underwent bilateral grafting, using a 1:1 mixture of autogenous bone particles (from iliac crest) and BG-particles at one side (experimental side), and bone particles only at the other side (control side, split mouth design). A total of 72 bone biopsies were taken at the time of fixture installation; that is, 3 patients at 4 months, 3 at 5 months and 3 at 6 months after grafting and 1 patient at 16 months (when she presented again). In each case 6 biopsies were taken, 3 left and 3 right. Histomorphometry showed that in grafts at control sides, trabecular bone was present after 4 months, comprising almost 41% of the tissue volume. This bone contained viable osteocytes and was of mature lamellar type and showed a mature histological appearance. Bone volume continued to increase slightly, to 42% at 5 months, 44% at 6 months and 45% at 16 months. The graft volume at experimental sides consisted at 4 months for 28% of woven and some lamellar bone, and increased to 35% at 5 months and 38% at 6 months, when mainly lamellar bone was found. At 16 months a lamellar bone volume of 45% was found. The BG-particles transformed and became excavated with time, starting at 4 months, and their centers gradually filled with bone tissue. All BG-particles had disappeared by resorption at 16 months after grafting and had been replaced by bone tissue. Parameters of bone turnover (% osteoid surface, % resorption surface, mineral apposition rate as measured by tetracycline labeling) indicated that bone remodeling was very active at both sides, during more than 6 months, despite the mature histological appearance of the bone tissue. From these histological observations, we conclude that a 1:1 mixture of autogenous bone/BG-particles seems a promising alternative to autogenous bone only, when low amounts of bone tissue are available for sinus augmentation.
PubMed: 11168226
Affiliations:
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Kulper</name></author><author><name sortKey="Burger, E H" sort="Burger, E H" uniqKey="Burger E" first="E H" last="Burger">E H Burger</name></author></analytic><series><title level="j">Clinical oral implants research</title><idno type="ISSN">0905-7161</idno><imprint><date when="2000" type="published">2000</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Absorbable Implants</term><term>Biocompatible Materials (chemistry)</term><term>Biocompatible Materials (therapeutic use)</term><term>Biopsy</term><term>Bone Matrix (pathology)</term><term>Bone Remodeling (physiology)</term><term>Bone Resorption (pathology)</term><term>Bone Substitutes (chemistry)</term><term>Bone Substitutes (therapeutic use)</term><term>Bone Transplantation (methods)</term><term>Dental Implantation, Endosseous</term><term>Dental Implants</term><term>Female</term><term>Fluorescent Dyes</term><term>Follow-Up Studies</term><term>Glass (chemistry)</term><term>Humans</term><term>Jaw, Edentulous (surgery)</term><term>Maxilla (surgery)</term><term>Maxillary Sinus (pathology)</term><term>Maxillary Sinus (surgery)</term><term>Middle Aged</term><term>Osteocytes (pathology)</term><term>Osteogenesis (physiology)</term><term>Tetracycline</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Biopsie</term><term>Colorants fluorescents</term><term>Femelle</term><term>Humains</term><term>Implant résorbable</term><term>Implants dentaires</term><term>Matériaux biocompatibles ()</term><term>Matériaux biocompatibles (usage thérapeutique)</term><term>Maxillaire ()</term><term>Mâchoire édentée ()</term><term>Ostéocytes (anatomopathologie)</term><term>Ostéogenèse (physiologie)</term><term>Pose d'implant dentaire endo-osseux</term><term>Remodelage osseux (physiologie)</term><term>Résorption osseuse (anatomopathologie)</term><term>Sinus maxillaire ()</term><term>Sinus maxillaire (anatomopathologie)</term><term>Substituts osseux ()</term><term>Substituts osseux (usage thérapeutique)</term><term>Trame osseuse (anatomopathologie)</term><term>Transplantation osseuse ()</term><term>Tétracycline</term><term>Verre ()</term><term>Études de suivi</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Biocompatible Materials</term><term>Bone Substitutes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Biocompatible Materials</term><term>Bone Substitutes</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Ostéocytes</term><term>Résorption osseuse</term><term>Sinus maxillaire</term><term>Trame osseuse</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Glass</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Bone Transplantation</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Bone Matrix</term><term>Bone Resorption</term><term>Maxillary Sinus</term><term>Osteocytes</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Ostéogenèse</term><term>Remodelage osseux</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Bone Remodeling</term><term>Osteogenesis</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Jaw, Edentulous</term><term>Maxilla</term><term>Maxillary Sinus</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Matériaux biocompatibles</term><term>Substituts osseux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Absorbable Implants</term><term>Biopsy</term><term>Dental Implantation, Endosseous</term><term>Dental Implants</term><term>Female</term><term>Fluorescent Dyes</term><term>Follow-Up Studies</term><term>Humans</term><term>Middle Aged</term><term>Tetracycline</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Biopsie</term><term>Colorants fluorescents</term><term>Femelle</term><term>Humains</term><term>Implant résorbable</term><term>Implants dentaires</term><term>Matériaux biocompatibles</term><term>Maxillaire</term><term>Mâchoire édentée</term><term>Pose d'implant dentaire endo-osseux</term><term>Sinus maxillaire</term><term>Substituts osseux</term><term>Transplantation osseuse</term><term>Tétracycline</term><term>Verre</term><term>Études de suivi</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We evaluated the bone augmenting capacity of bioactive glass particles, size range 300-355 microns (BG-particles), in human sinus floor elevations using histomorphometrical methods. A total of 10 patients underwent bilateral grafting, using a 1:1 mixture of autogenous bone particles (from iliac crest) and BG-particles at one side (experimental side), and bone particles only at the other side (control side, split mouth design). A total of 72 bone biopsies were taken at the time of fixture installation; that is, 3 patients at 4 months, 3 at 5 months and 3 at 6 months after grafting and 1 patient at 16 months (when she presented again). In each case 6 biopsies were taken, 3 left and 3 right. Histomorphometry showed that in grafts at control sides, trabecular bone was present after 4 months, comprising almost 41% of the tissue volume. This bone contained viable osteocytes and was of mature lamellar type and showed a mature histological appearance. Bone volume continued to increase slightly, to 42% at 5 months, 44% at 6 months and 45% at 16 months. The graft volume at experimental sides consisted at 4 months for 28% of woven and some lamellar bone, and increased to 35% at 5 months and 38% at 6 months, when mainly lamellar bone was found. At 16 months a lamellar bone volume of 45% was found. The BG-particles transformed and became excavated with time, starting at 4 months, and their centers gradually filled with bone tissue. All BG-particles had disappeared by resorption at 16 months after grafting and had been replaced by bone tissue. Parameters of bone turnover (% osteoid surface, % resorption surface, mineral apposition rate as measured by tetracycline labeling) indicated that bone remodeling was very active at both sides, during more than 6 months, despite the mature histological appearance of the bone tissue. From these histological observations, we conclude that a 1:1 mixture of autogenous bone/BG-particles seems a promising alternative to autogenous bone only, when low amounts of bone tissue are available for sinus augmentation.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">11168226</PMID><DateCompleted><Year>2001</Year><Month>04</Month><Day>26</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0905-7161</ISSN><JournalIssue CitedMedium="Print"><Volume>11</Volume><Issue>4</Issue><PubDate><Year>2000</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Clinical oral implants research</Title><ISOAbbreviation>Clin Oral Implants Res</ISOAbbreviation></Journal><ArticleTitle>Histological observations on biopsies harvested following sinus floor elevation using a bioactive glass material of narrow size range.</ArticleTitle><Pagination><MedlinePgn>334-44</MedlinePgn></Pagination><Abstract><AbstractText>We evaluated the bone augmenting capacity of bioactive glass particles, size range 300-355 microns (BG-particles), in human sinus floor elevations using histomorphometrical methods. A total of 10 patients underwent bilateral grafting, using a 1:1 mixture of autogenous bone particles (from iliac crest) and BG-particles at one side (experimental side), and bone particles only at the other side (control side, split mouth design). A total of 72 bone biopsies were taken at the time of fixture installation; that is, 3 patients at 4 months, 3 at 5 months and 3 at 6 months after grafting and 1 patient at 16 months (when she presented again). In each case 6 biopsies were taken, 3 left and 3 right. Histomorphometry showed that in grafts at control sides, trabecular bone was present after 4 months, comprising almost 41% of the tissue volume. This bone contained viable osteocytes and was of mature lamellar type and showed a mature histological appearance. Bone volume continued to increase slightly, to 42% at 5 months, 44% at 6 months and 45% at 16 months. The graft volume at experimental sides consisted at 4 months for 28% of woven and some lamellar bone, and increased to 35% at 5 months and 38% at 6 months, when mainly lamellar bone was found. At 16 months a lamellar bone volume of 45% was found. The BG-particles transformed and became excavated with time, starting at 4 months, and their centers gradually filled with bone tissue. All BG-particles had disappeared by resorption at 16 months after grafting and had been replaced by bone tissue. Parameters of bone turnover (% osteoid surface, % resorption surface, mineral apposition rate as measured by tetracycline labeling) indicated that bone remodeling was very active at both sides, during more than 6 months, despite the mature histological appearance of the bone tissue. From these histological observations, we conclude that a 1:1 mixture of autogenous bone/BG-particles seems a promising alternative to autogenous bone only, when low amounts of bone tissue are available for sinus augmentation.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tadjoedin</LastName><ForeName>E S</ForeName><Initials>ES</Initials><AffiliationInfo><Affiliation>Department of Oral Cell Biology, Academic Center for Dentistry Amsterdam (ACTA), Vrije Universiteit, Amsterdam, van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Lange</LastName><ForeName>G L</ForeName><Initials>GL</Initials></Author><Author ValidYN="Y"><LastName>Holzmann</LastName><ForeName>P J</ForeName><Initials>PJ</Initials></Author><Author ValidYN="Y"><LastName>Kulper</LastName><ForeName>L</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Burger</LastName><ForeName>E H</ForeName><Initials>EH</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D018848">Controlled Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Denmark</Country><MedlineTA>Clin Oral Implants Res</MedlineTA><NlmUniqueID>9105713</NlmUniqueID><ISSNLinking>0905-7161</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001672">Biocompatible Materials</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C073544">Biogran</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018786">Bone Substitutes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015921">Dental Implants</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005456">Fluorescent Dyes</NameOfSubstance></Chemical><Chemical><RegistryNumber>F8VB5M810T</RegistryNumber><NameOfSubstance UI="D013752">Tetracycline</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D020341" MajorTopicYN="N">Absorbable Implants</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001672" MajorTopicYN="N">Biocompatible Materials</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001706" MajorTopicYN="N">Biopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001857" MajorTopicYN="N">Bone Matrix</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016723" MajorTopicYN="N">Bone Remodeling</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001862" MajorTopicYN="N">Bone Resorption</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018786" MajorTopicYN="N">Bone Substitutes</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016025" MajorTopicYN="Y">Bone Transplantation</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003758" MajorTopicYN="N">Dental Implantation, Endosseous</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015921" MajorTopicYN="N">Dental Implants</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005456" MajorTopicYN="N">Fluorescent Dyes</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005898" MajorTopicYN="N">Glass</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007575" MajorTopicYN="N">Jaw, Edentulous</DescriptorName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008437" MajorTopicYN="N">Maxilla</DescriptorName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008443" MajorTopicYN="N">Maxillary Sinus</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010011" MajorTopicYN="N">Osteocytes</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010012" MajorTopicYN="N">Osteogenesis</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013752" MajorTopicYN="N">Tetracycline</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>2</Month><Day>13</Day><Hour>11</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>5</Month><Day>1</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>2</Month><Day>13</Day><Hour>11</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11168226</ArticleId><ArticleId IdType="pii">clr110407</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Pays-Bas</li></country><region><li>Hollande-Septentrionale</li></region><settlement><li>Amsterdam</li></settlement></list><tree><noCountry><name sortKey="Burger, E H" sort="Burger, E H" uniqKey="Burger E" first="E H" last="Burger">E H Burger</name><name sortKey="De Lange, G L" sort="De Lange, G L" uniqKey="De Lange G" first="G L" last="De Lange">G L De Lange</name><name sortKey="Holzmann, P J" sort="Holzmann, P J" uniqKey="Holzmann P" first="P J" last="Holzmann">P J Holzmann</name><name sortKey="Kulper, L" sort="Kulper, L" uniqKey="Kulper L" first="L" last="Kulper">L. Kulper</name></noCountry><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Tadjoedin, E S" sort="Tadjoedin, E S" uniqKey="Tadjoedin E" first="E S" last="Tadjoedin">E S Tadjoedin</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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