Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases
Identifieur interne : 002724 ( Pmc/Curation ); précédent : 002723; suivant : 002725Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases
Auteurs : Tara L. Aghaloo ; Sotirios TetradisSource :
- Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons [ 0278-2391 ] ; 2016.
Abstract
Medication-related osteonecrosis of the jaws (MRONJ) is a well-described complication of anti-resorptive and antiangiogenic medications. Although osteonecrosis can be associated with other inciting events and medications, such as trauma, infection, steroids, chemotherapy, and coagulation disorders, these are rarely reported in the literature.
This is a six case series of MRONJ associated with medications other than anti-resorptive or antiangiogenic drugs.
Patient demographics, incitingevent, location, stage, imaging findings, and outcome are reported.
With the continued development and clinical use of new biologic medications for diseases such as cancer and rheumatoid arthritis, it is important to continue to evaluate their effects on the oral cavity. The degree of risk for osteonecrosis in patients taking these new classes of drugs is uncertain but warrants awareness and monitoring.
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DOI: 10.1016/j.joms.2016.07.019
PubMed: 27569557
PubMed Central: 5527276
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases</title><author><name sortKey="Aghaloo, Tara L" sort="Aghaloo, Tara L" uniqKey="Aghaloo T" first="Tara L." last="Aghaloo">Tara L. Aghaloo</name></author><author><name sortKey="Tetradis, Sotirios" sort="Tetradis, Sotirios" uniqKey="Tetradis S" first="Sotirios" last="Tetradis">Sotirios Tetradis</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27569557</idno><idno type="pmc">5527276</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527276</idno><idno type="RBID">PMC:5527276</idno><idno type="doi">10.1016/j.joms.2016.07.019</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">002724</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002724</idno><idno type="wicri:Area/Pmc/Curation">002724</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002724</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases</title><author><name sortKey="Aghaloo, Tara L" sort="Aghaloo, Tara L" uniqKey="Aghaloo T" first="Tara L." last="Aghaloo">Tara L. Aghaloo</name></author><author><name sortKey="Tetradis, Sotirios" sort="Tetradis, Sotirios" uniqKey="Tetradis S" first="Sotirios" last="Tetradis">Sotirios Tetradis</name></author></analytic><series><title level="j">Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons</title><idno type="ISSN">0278-2391</idno><idno type="eISSN">1531-5053</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Purpose</title><p id="P1">Medication-related osteonecrosis of the jaws (MRONJ) is a well-described complication of anti-resorptive and antiangiogenic medications. Although osteonecrosis can be associated with other inciting events and medications, such as trauma, infection, steroids, chemotherapy, and coagulation disorders, these are rarely reported in the literature.</p></sec><sec id="S2"><title>Materials and Methods</title><p id="P2">This is a six case series of MRONJ associated with medications other than anti-resorptive or antiangiogenic drugs.</p></sec><sec id="S3"><title>Results</title><p id="P3">Patient demographics, incitingevent, location, stage, imaging findings, and outcome are reported.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">With the continued development and clinical use of new biologic medications for diseases such as cancer and rheumatoid arthritis, it is important to continue to evaluate their effects on the oral cavity. The degree of risk for osteonecrosis in patients taking these new classes of drugs is uncertain but warrants awareness and monitoring.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8206428</journal-id><journal-id journal-id-type="pubmed-jr-id">5090</journal-id><journal-id journal-id-type="nlm-ta">J Oral Maxillofac Surg</journal-id><journal-id journal-id-type="iso-abbrev">J. Oral Maxillofac. Surg.</journal-id><journal-title-group><journal-title>Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons</journal-title></journal-title-group><issn pub-type="ppub">0278-2391</issn><issn pub-type="epub">1531-5053</issn></journal-meta><article-meta><article-id pub-id-type="pmid">27569557</article-id><article-id pub-id-type="pmc">5527276</article-id><article-id pub-id-type="doi">10.1016/j.joms.2016.07.019</article-id><article-id pub-id-type="manuscript">NIHMS880235</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Aghaloo</surname><given-names>Tara L.</given-names></name><degrees>DDS, MD, PhD</degrees><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Tetradis</surname><given-names>Sotirios</given-names></name><degrees>DDS, PhD</degrees><xref rid="FN3" ref-type="author-notes">†</xref></contrib><aff id="A1">Section of Oral and Maxillofacial Surgery, Division of Diagnostic and Surgical Sciences, UCLA School of Dentistry, Los Angeles, CA</aff></contrib-group><author-notes><corresp id="FN1">Address correspondence and reprint requests to: Dr Aghaloo: Section of Oral and Maxillofacial Surgery, Division of Diagnostic and Surgical Sciences, UCLA School of Dentistry, 10833 LeConte Avenue, CHS Room 53-076, Los Angeles, CA 90095-1668; <email>taghaloo@dentistry.ucla.edu</email></corresp><fn id="FN2"><label>*</label><p>Professor.</p></fn><fn id="FN3"><label>†</label><p>Professor.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>31</day><month>5</month><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>7</month><year>2016</year></pub-date><pub-date pub-type="ppub"><month>1</month><year>2017</year></pub-date><pub-date pub-type="pmc-release"><day>26</day><month>7</month><year>2017</year></pub-date><volume>75</volume><issue>1</issue><fpage>129</fpage><lpage>142</lpage><pmc-comment>elocation-id from pubmed: 10.1016/j.joms.2016.07.019</pmc-comment>
<abstract><sec id="S1"><title>Purpose</title><p id="P1">Medication-related osteonecrosis of the jaws (MRONJ) is a well-described complication of anti-resorptive and antiangiogenic medications. Although osteonecrosis can be associated with other inciting events and medications, such as trauma, infection, steroids, chemotherapy, and coagulation disorders, these are rarely reported in the literature.</p></sec><sec id="S2"><title>Materials and Methods</title><p id="P2">This is a six case series of MRONJ associated with medications other than anti-resorptive or antiangiogenic drugs.</p></sec><sec id="S3"><title>Results</title><p id="P3">Patient demographics, incitingevent, location, stage, imaging findings, and outcome are reported.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">With the continued development and clinical use of new biologic medications for diseases such as cancer and rheumatoid arthritis, it is important to continue to evaluate their effects on the oral cavity. The degree of risk for osteonecrosis in patients taking these new classes of drugs is uncertain but warrants awareness and monitoring.</p></sec></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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