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Power spectrum density analysis for the influence of complete denture on the brain function of edentulous patients - pilot study

Identifieur interne : 000660 ( Pmc/Curation ); précédent : 000659; suivant : 000661

Power spectrum density analysis for the influence of complete denture on the brain function of edentulous patients - pilot study

Auteurs : Praveen Perumal [Inde] ; Gopi Naveen Chander [Inde] ; Kuttae Viswanathan Anitha [Inde] ; Jetti Ramesh Reddy [Inde] ; Balasubramanium Muthukumar [Inde]

Source :

RBID : PMC:4919488

Abstract

PURPOSE

This pilot study was to find the influence of complete denture on the brain activity and cognitive function of edentulous patients measured through Electroencephalogram (EEG) signals.

MATERIALS AND METHODS

The study recruited 20 patients aged from 50 to 60 years requiring complete dentures with inclusion and exclusion criteria. The brain function and cognitive function were analyzed with a mental state questionnaire and a 15-minute analysis of power spectral density of EEG alpha waves. The analysis included edentulous phase and post denture insertion adaptive phase, each done before and after chewing. The results obtained were statistically evaluated.

RESULTS

Power Spectral Density (PSD) values increased from edentulous phase to post denture insertion adaption phase. The data were grouped as edentulous phase before chewing (EEG p1-0.0064), edentulous phase after chewing (EEG p2-0.0073), post denture insertion adaptive phase before chewing (EEG p3-0.0077), and post denture insertion adaptive phase after chewing (EEG p4-0.0096). The acquired values were statistically analyzed using paired t-test, which showed statistically significant results (P<.05).

CONCLUSION

This pilot study showed functional improvement in brain function of edentulous patients with complete dentures rehabilitation.


Url:
DOI: 10.4047/jap.2016.8.3.187
PubMed: 27350852
PubMed Central: 4919488

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PMC:4919488

Le document en format XML

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<title>MATERIALS AND METHODS</title>
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</TEI>
<pmc article-type="research-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Adv Prosthodont</journal-id>
<journal-id journal-id-type="iso-abbrev">J Adv Prosthodont</journal-id>
<journal-id journal-id-type="publisher-id">JAP</journal-id>
<journal-title-group>
<journal-title>The Journal of Advanced Prosthodontics</journal-title>
</journal-title-group>
<issn pub-type="ppub">2005-7806</issn>
<issn pub-type="epub">2005-7814</issn>
<publisher>
<publisher-name>The Korean Academy of Prosthodontics</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27350852</article-id>
<article-id pub-id-type="pmc">4919488</article-id>
<article-id pub-id-type="doi">10.4047/jap.2016.8.3.187</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Power spectrum density analysis for the influence of complete denture on the brain function of edentulous patients - pilot study</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Perumal</surname>
<given-names>Praveen</given-names>
</name>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid" authenticated="true">http://orcid.org/0000-0002-2040-4550</contrib-id>
<name>
<surname>Chander</surname>
<given-names>Gopi Naveen</given-names>
</name>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Anitha</surname>
<given-names>Kuttae Viswanathan</given-names>
</name>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Reddy</surname>
<given-names>Jetti Ramesh</given-names>
</name>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Muthukumar</surname>
<given-names>Balasubramanium</given-names>
</name>
<xref ref-type="aff" rid="A1"></xref>
</contrib>
</contrib-group>
<aff id="A1">Department of Prosthodontics, SRM Dental College, Ramapuram, Chennai, India.</aff>
<author-notes>
<corresp>Corresponding author: Gopi Naveen Chander. Department of Prosthodontics, SRM Dental College, #496, 3rd Main Road, TNHB Colony, Velachery, Chennai -42. India. Tel. 919840749441:
<email>drgopichander@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>6</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>17</day>
<month>6</month>
<year>2016</year>
</pub-date>
<volume>8</volume>
<issue>3</issue>
<fpage>187</fpage>
<lpage>193</lpage>
<history>
<date date-type="received">
<day>12</day>
<month>9</month>
<year>2015</year>
</date>
<date date-type="rev-recd">
<day>01</day>
<month>2</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>24</day>
<month>3</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© 2016 The Korean Academy of Prosthodontics</copyright-statement>
<copyright-year>2016</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">
<license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (
<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>
) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract>
<sec>
<title>PURPOSE</title>
<p>This pilot study was to find the influence of complete denture on the brain activity and cognitive function of edentulous patients measured through Electroencephalogram (EEG) signals.</p>
</sec>
<sec>
<title>MATERIALS AND METHODS</title>
<p>The study recruited 20 patients aged from 50 to 60 years requiring complete dentures with inclusion and exclusion criteria. The brain function and cognitive function were analyzed with a mental state questionnaire and a 15-minute analysis of power spectral density of EEG alpha waves. The analysis included edentulous phase and post denture insertion adaptive phase, each done before and after chewing. The results obtained were statistically evaluated.</p>
</sec>
<sec>
<title>RESULTS</title>
<p>Power Spectral Density (PSD) values increased from edentulous phase to post denture insertion adaption phase. The data were grouped as edentulous phase before chewing (EEG p1-0.0064), edentulous phase after chewing (EEG p2-0.0073), post denture insertion adaptive phase before chewing (EEG p3-0.0077), and post denture insertion adaptive phase after chewing (EEG p4-0.0096). The acquired values were statistically analyzed using paired t-test, which showed statistically significant results (
<italic>P</italic>
<.05).</p>
</sec>
<sec>
<title>CONCLUSION</title>
<p>This pilot study showed functional improvement in brain function of edentulous patients with complete dentures rehabilitation.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Power Spectral Density</kwd>
<kwd>Fast Fourier Transform</kwd>
<kwd>Brain activity</kwd>
<kwd>Geriatric</kwd>
<kwd>Electroencephalography</kwd>
<kwd>Complete denture</kwd>
</kwd-group>
</article-meta>
</front>
<floats-group>
<fig id="F1" orientation="portrait" position="float">
<label>Fig. 1</label>
<caption>
<title>Study procedure flow chart.</title>
</caption>
<graphic xlink:href="jap-8-187-g001"></graphic>
</fig>
<fig id="F2" orientation="portrait" position="float">
<label>Fig. 2</label>
<caption>
<title>Flow chart for EEG measurement.</title>
</caption>
<graphic xlink:href="jap-8-187-g002"></graphic>
</fig>
<fig id="F3" orientation="portrait" position="float">
<label>Fig. 3</label>
<caption>
<title>Data acquisition of EEG.</title>
</caption>
<graphic xlink:href="jap-8-187-g003"></graphic>
</fig>
<fig id="F4" orientation="portrait" position="float">
<label>Fig. 4</label>
<caption>
<title>Flow Chart for EEG Analysis.</title>
</caption>
<graphic xlink:href="jap-8-187-g004"></graphic>
</fig>
<fig id="F5" orientation="portrait" position="float">
<label>Fig. 5</label>
<caption>
<title>Power spectral density value.</title>
</caption>
<graphic xlink:href="jap-8-187-g005"></graphic>
</fig>
<fig id="F6" orientation="portrait" position="float">
<label>Fig. 6</label>
<caption>
<title>Mean values of edentulous phase and post denture insertion adaptive phase before and after chewing.</title>
</caption>
<graphic xlink:href="jap-8-187-g006"></graphic>
</fig>
<table-wrap id="T1" orientation="portrait" position="float">
<label>Table 1</label>
<caption>
<title>Power spectral density (relative units)</title>
</caption>
<alternatives>
<graphic xlink:href="jap-8-187-i001"></graphic>
<table frame="hsides" rules="rows">
<col width="20%" span="1"></col>
<col width="20%" span="1"></col>
<col width="20%" span="1"></col>
<col width="20%" span="1"></col>
<col width="20%" span="1"></col>
<thead>
<tr>
<th valign="top" align="center" rowspan="1" colspan="1">S. NO:</th>
<th valign="top" align="center" rowspan="1" colspan="1">EEG P1</th>
<th valign="top" align="center" rowspan="1" colspan="1">EEG P2</th>
<th valign="top" align="center" rowspan="1" colspan="1">EEG P3</th>
<th valign="top" align="center" rowspan="1" colspan="1">EEG P4</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="center" rowspan="1" colspan="1">1</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.0025</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.0034</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.0038</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.0053</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">2</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0039</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0042</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0051</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0074</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">3</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0095</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0107</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0131</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0188</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">4</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0039</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0042</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0057</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0061</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">5</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0133</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0141</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0133</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0154</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">6</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0062</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0078</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0099</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0121</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">7</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0021</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0023</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0039</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0042</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">8</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0058</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0119</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0085</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0123</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">9</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0012</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0067</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0042</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0080</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">10</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0016</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0025</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0026</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0054</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">11</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0121</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0131</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0167</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0170</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">12</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0049</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0049</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0032</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0046</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">13</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0026</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0013</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0018</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0032</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">14</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0133</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0143</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0133</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0178</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">15</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0039</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0045</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0042</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0055</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">16</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0082</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0093</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0095</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0096</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">17</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0056</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0058</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0067</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0069</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">18</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0124</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0135</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0114</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0144</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">19</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0067</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0074</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0087</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0089</td>
</tr>
<tr>
<td valign="top" align="center" rowspan="1" colspan="1">20</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0075</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0076</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0078</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.0083</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot>
<fn>
<p>EEG p1: Edentulous phase before chewing, EEG p2: Edentulous phase after chewing, EEG p3: Post denture insertion adaptive phase before chewing, EEG p4: Post denture insertion adaptive phase after chewing.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="T2" orientation="portrait" position="float">
<label>Table 2</label>
<caption>
<title>Paired samples t-test to compare the mean value</title>
</caption>
<alternatives>
<graphic xlink:href="jap-8-187-i002"></graphic>
<table frame="hsides" rules="rows">
<col width="15%" span="1"></col>
<col width="15%" span="1"></col>
<col width="14%" span="1"></col>
<col width="14%" span="1"></col>
<col width="14%" span="1"></col>
<col width="14%" span="1"></col>
<col width="14%" span="1"></col>
<thead>
<tr>
<th valign="middle" align="center" rowspan="1" colspan="1">Pair</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Variables</th>
<th valign="middle" align="center" rowspan="1" colspan="1">N</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Mean</th>
<th valign="middle" align="center" rowspan="1" colspan="1">SD</th>
<th valign="middle" align="center" rowspan="1" colspan="1">t value</th>
<th valign="middle" align="center" rowspan="1" colspan="1">
<italic>P</italic>
value</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="center" rowspan="2" colspan="1">Pair 1</td>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p1</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.00641</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0039</td>
<td valign="middle" align="right" rowspan="2" colspan="1">3.566</td>
<td valign="middle" align="right" rowspan="2" colspan="1">.002</td>
</tr>
<tr>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p3</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0077</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0042</td>
</tr>
<tr>
<td valign="middle" align="center" rowspan="2" colspan="1">Pair 2</td>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p2</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0073</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0039</td>
<td valign="middle" align="right" rowspan="2" colspan="1">4.974</td>
<td valign="middle" align="right" rowspan="2" colspan="1">< .001</td>
</tr>
<tr>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p4</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0096</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0048</td>
</tr>
<tr>
<td valign="middle" align="center" rowspan="2" colspan="1">Pair 3</td>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p1</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0064</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0039</td>
<td valign="middle" align="right" rowspan="2" colspan="1">3.671</td>
<td valign="middle" align="right" rowspan="2" colspan="1">.002</td>
</tr>
<tr>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p2</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0073</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0039</td>
</tr>
<tr>
<td valign="middle" align="center" rowspan="2" colspan="1">Pair 4</td>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p3</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0077</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0042</td>
<td valign="middle" align="right" rowspan="2" colspan="1">5.202</td>
<td valign="middle" align="right" rowspan="2" colspan="1">< .001</td>
</tr>
<tr>
<td valign="middle" align="center" rowspan="1" colspan="1">EEG p4</td>
<td valign="middle" align="center" rowspan="1" colspan="1">20</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0096</td>
<td valign="middle" align="left" rowspan="1" colspan="1">0.0048</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot>
<fn>
<p>EEG p1: Edentulous phase before chewing, EEG p2: Edentulous phase after chewing, EEG p3: Post denture insertion adaptive phase before chewing, EEG p4: Post denture insertion adaptive phase after chewing.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</pmc>
</record>

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