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Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.

Identifieur interne : 009345 ( Ncbi/Curation ); précédent : 009344; suivant : 009346

Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.

Auteurs : C F Streckfus ; S. Marcus ; S. Welsh ; R S Brown ; G. Cherry-Peppers ; R H Brown

Source :

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology [ 0904-2512 ] ; 1994.

RBID : pubmed:7932247

Descripteurs français

KwdFr :
- Analyse de variance, Baltimore, Bouche édentée, Diabète (), Diabète (physiopathologie), Diabète de type 1 (physiopathologie), Diabète de type 1 (traitement médicamenteux), Diabète de type 2 (), Diabète de type 2 (physiopathologie), Diétothérapie, Débit sécrétoire, Femelle, Glande parotide (sécrétion), Humains, Immunoglobuline A sécrétoire (analyse), Insuline (usage thérapeutique), Mâle, Population d'origine africaine, Protéines et peptides salivaires (analyse), Salivation, Salive (), Salive (sécrétion), Sujet âgé, Tolbutamide (usage thérapeutique), Électrolytes (analyse), Études cas-témoins.
MESH :
- analyse : Immunoglobuline A sécrétoire, Protéines et peptides salivaires, Électrolytes.
- physiopathologie : Diabète, Diabète de type 1, Diabète de type 2.
- sécrétion : Glande parotide, Salive.
- traitement médicamenteux : Diabète de type 1.
- usage thérapeutique : Insuline, Tolbutamide.
- Analyse de variance, Baltimore, Bouche édentée, Diabète, Diabète de type 2, Diétothérapie, Débit sécrétoire, Femelle, Humains, Mâle, Population d'origine africaine, Salivation, Salive, Sujet âgé, Études cas-témoins.

English descriptors

KwdEn :
- African Continental Ancestry Group, Aged, Analysis of Variance, Baltimore, Case-Control Studies, Diabetes Mellitus (physiopathology), Diabetes Mellitus (therapy), Diabetes Mellitus, Type 1 (drug therapy), Diabetes Mellitus, Type 1 (physiopathology), Diabetes Mellitus, Type 2 (physiopathology), Diabetes Mellitus, Type 2 (therapy), Diet Therapy, Electrolytes (analysis), Female, Humans, Immunoglobulin A, Secretory (analysis), Insulin (therapeutic use), Male, Mouth, Edentulous, Parotid Gland (secretion), Saliva (chemistry), Saliva (secretion), Salivary Proteins and Peptides (analysis), Salivation, Secretory Rate, Tolbutamide (therapeutic use).
MESH :
- chemical , analysis : Electrolytes, Immunoglobulin A, Secretory, Salivary Proteins and Peptides.
- chemical , therapeutic use : Insulin, Tolbutamide.
- geographic : Baltimore.
- chemistry : Saliva.
- drug therapy : Diabetes Mellitus, Type 1.
- physiopathology : Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2.
- secretion : Parotid Gland, Saliva.
- therapy : Diabetes Mellitus, Diabetes Mellitus, Type 2.
- African Continental Ancestry Group, Aged, Analysis of Variance, Case-Control Studies, Diet Therapy, Female, Humans, Male, Mouth, Edentulous, Salivation, Secretory Rate.

Abstract

This study examined parotid salivary flow rate and composition in three groups of differently treated diabetics and a control group of non-diabetics. The study population was composed of edentulous African-Americans at least 65 years of age. Group A was the control, Group B insulin-dependent (Regular Iletin, U-100 qd.), Group C controlled by oral medication (Tolbutamide, 500 mg qd.), and Group D was diet controlled. All diabetic patients had serum glucose values under 250 mg/dl. Salivary flow rates, secretory IgA, electrolytes (Na+, Cl-, K+, Ca++) and total protein concentrations were evaluated. The results showed no significant differences between groups with respect to salivary flow rates, electrolytes and IgA concentrations. Additionally, all diabetic groups demonstrated a significantly lower salivary total protein concentration when compared to the controls. There appears to be no evident decrease in salivary flow rate in these three differently controlled diabetic groups compared with healthy non-diabetics.

PubMed: 7932247

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C F Streckfus

<affiliation><nlm:affiliation>Epidemiology and Oral Disease Prevention Program, National Institute of Dental Research, NIH, Bethesda, Md 20892.</nlm:affiliation>
<wicri:noCountry code="subField">Md 20892</wicri:noCountry>
</affiliation>

Le document en format XML

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<term>Aged</term>
<term>Analysis of Variance</term>
<term>Baltimore</term>
<term>Case-Control Studies</term>
<term>Diabetes Mellitus (physiopathology)</term>
<term>Diabetes Mellitus (therapy)</term>
<term>Diabetes Mellitus, Type 1 (drug therapy)</term>
<term>Diabetes Mellitus, Type 1 (physiopathology)</term>
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<term>Diabetes Mellitus, Type 2 (therapy)</term>
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<term>Electrolytes (analysis)</term>
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<term>Humans</term>
<term>Immunoglobulin A, Secretory (analysis)</term>
<term>Insulin (therapeutic use)</term>
<term>Male</term>
<term>Mouth, Edentulous</term>
<term>Parotid Gland (secretion)</term>
<term>Saliva (chemistry)</term>
<term>Saliva (secretion)</term>
<term>Salivary Proteins and Peptides (analysis)</term>
<term>Salivation</term>
<term>Secretory Rate</term>
<term>Tolbutamide (therapeutic use)</term>
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<term>Baltimore</term>
<term>Bouche édentée</term>
<term>Diabète ()</term>
<term>Diabète (physiopathologie)</term>
<term>Diabète de type 1 (physiopathologie)</term>
<term>Diabète de type 1 (traitement médicamenteux)</term>
<term>Diabète de type 2 ()</term>
<term>Diabète de type 2 (physiopathologie)</term>
<term>Diétothérapie</term>
<term>Débit sécrétoire</term>
<term>Femelle</term>
<term>Glande parotide (sécrétion)</term>
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<term>Diabetes Mellitus, Type 2</term>
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<term>Analysis of Variance</term>
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<term>Mouth, Edentulous</term>
<term>Salivation</term>
<term>Secretory Rate</term>
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<term>Baltimore</term>
<term>Bouche édentée</term>
<term>Diabète</term>
<term>Diabète de type 2</term>
<term>Diétothérapie</term>
<term>Débit sécrétoire</term>
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<front><div type="abstract" xml:lang="en">This study examined parotid salivary flow rate and composition in three groups of differently treated diabetics and a control group of non-diabetics. The study population was composed of edentulous African-Americans at least 65 years of age. Group A was the control, Group B insulin-dependent (Regular Iletin, U-100 qd.), Group C controlled by oral medication (Tolbutamide, 500 mg qd.), and Group D was diet controlled. All diabetic patients had serum glucose values under 250 mg/dl. Salivary flow rates, secretory IgA, electrolytes (Na+, Cl-, K+, Ca++) and total protein concentrations were evaluated. The results showed no significant differences between groups with respect to salivary flow rates, electrolytes and IgA concentrations. Additionally, all diabetic groups demonstrated a significantly lower salivary total protein concentration when compared to the controls. There appears to be no evident decrease in salivary flow rate in these three differently controlled diabetic groups compared with healthy non-diabetics.</div>
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Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.

Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.

Source :

Descripteurs français

English descriptors

Abstract

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Curation

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