Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.
Identifieur interne : 009345 ( Ncbi/Merge ); précédent : 009344; suivant : 009346Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.
Auteurs : C F Streckfus ; S. Marcus ; S. Welsh ; R S Brown ; G. Cherry-Peppers ; R H BrownSource :
- Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology [ 0904-2512 ] ; 1994.
Descripteurs français
- KwdFr :
- Analyse de variance, Baltimore, Bouche édentée, Diabète (), Diabète (physiopathologie), Diabète de type 1 (physiopathologie), Diabète de type 1 (traitement médicamenteux), Diabète de type 2 (), Diabète de type 2 (physiopathologie), Diétothérapie, Débit sécrétoire, Femelle, Glande parotide (sécrétion), Humains, Immunoglobuline A sécrétoire (analyse), Insuline (usage thérapeutique), Mâle, Population d'origine africaine, Protéines et peptides salivaires (analyse), Salivation, Salive (), Salive (sécrétion), Sujet âgé, Tolbutamide (usage thérapeutique), Électrolytes (analyse), Études cas-témoins.
- MESH :
- analyse : Immunoglobuline A sécrétoire, Protéines et peptides salivaires, Électrolytes.
- physiopathologie : Diabète, Diabète de type 1, Diabète de type 2.
- sécrétion : Glande parotide, Salive.
- traitement médicamenteux : Diabète de type 1.
- usage thérapeutique : Insuline, Tolbutamide.
- Analyse de variance, Baltimore, Bouche édentée, Diabète, Diabète de type 2, Diétothérapie, Débit sécrétoire, Femelle, Humains, Mâle, Population d'origine africaine, Salivation, Salive, Sujet âgé, Études cas-témoins.
English descriptors
- KwdEn :
- African Continental Ancestry Group, Aged, Analysis of Variance, Baltimore, Case-Control Studies, Diabetes Mellitus (physiopathology), Diabetes Mellitus (therapy), Diabetes Mellitus, Type 1 (drug therapy), Diabetes Mellitus, Type 1 (physiopathology), Diabetes Mellitus, Type 2 (physiopathology), Diabetes Mellitus, Type 2 (therapy), Diet Therapy, Electrolytes (analysis), Female, Humans, Immunoglobulin A, Secretory (analysis), Insulin (therapeutic use), Male, Mouth, Edentulous, Parotid Gland (secretion), Saliva (chemistry), Saliva (secretion), Salivary Proteins and Peptides (analysis), Salivation, Secretory Rate, Tolbutamide (therapeutic use).
- MESH :
- chemical , analysis : Electrolytes, Immunoglobulin A, Secretory, Salivary Proteins and Peptides.
- chemical , therapeutic use : Insulin, Tolbutamide.
- geographic : Baltimore.
- chemistry : Saliva.
- drug therapy : Diabetes Mellitus, Type 1.
- physiopathology : Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2.
- secretion : Parotid Gland, Saliva.
- therapy : Diabetes Mellitus, Diabetes Mellitus, Type 2.
- African Continental Ancestry Group, Aged, Analysis of Variance, Case-Control Studies, Diet Therapy, Female, Humans, Male, Mouth, Edentulous, Salivation, Secretory Rate.
Abstract
This study examined parotid salivary flow rate and composition in three groups of differently treated diabetics and a control group of non-diabetics. The study population was composed of edentulous African-Americans at least 65 years of age. Group A was the control, Group B insulin-dependent (Regular Iletin, U-100 qd.), Group C controlled by oral medication (Tolbutamide, 500 mg qd.), and Group D was diet controlled. All diabetic patients had serum glucose values under 250 mg/dl. Salivary flow rates, secretory IgA, electrolytes (Na+, Cl-, K+, Ca++) and total protein concentrations were evaluated. The results showed no significant differences between groups with respect to salivary flow rates, electrolytes and IgA concentrations. Additionally, all diabetic groups demonstrated a significantly lower salivary total protein concentration when compared to the controls. There appears to be no evident decrease in salivary flow rate in these three differently controlled diabetic groups compared with healthy non-diabetics.
PubMed: 7932247
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pubmed:7932247Le document en format XML
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<term>Aged</term>
<term>Analysis of Variance</term>
<term>Baltimore</term>
<term>Case-Control Studies</term>
<term>Diabetes Mellitus (physiopathology)</term>
<term>Diabetes Mellitus (therapy)</term>
<term>Diabetes Mellitus, Type 1 (drug therapy)</term>
<term>Diabetes Mellitus, Type 1 (physiopathology)</term>
<term>Diabetes Mellitus, Type 2 (physiopathology)</term>
<term>Diabetes Mellitus, Type 2 (therapy)</term>
<term>Diet Therapy</term>
<term>Electrolytes (analysis)</term>
<term>Female</term>
<term>Humans</term>
<term>Immunoglobulin A, Secretory (analysis)</term>
<term>Insulin (therapeutic use)</term>
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<term>Mouth, Edentulous</term>
<term>Parotid Gland (secretion)</term>
<term>Saliva (chemistry)</term>
<term>Saliva (secretion)</term>
<term>Salivary Proteins and Peptides (analysis)</term>
<term>Salivation</term>
<term>Secretory Rate</term>
<term>Tolbutamide (therapeutic use)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de variance</term>
<term>Baltimore</term>
<term>Bouche édentée</term>
<term>Diabète ()</term>
<term>Diabète (physiopathologie)</term>
<term>Diabète de type 1 (physiopathologie)</term>
<term>Diabète de type 1 (traitement médicamenteux)</term>
<term>Diabète de type 2 ()</term>
<term>Diabète de type 2 (physiopathologie)</term>
<term>Diétothérapie</term>
<term>Débit sécrétoire</term>
<term>Femelle</term>
<term>Glande parotide (sécrétion)</term>
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<term>Salive (sécrétion)</term>
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<term>Tolbutamide (usage thérapeutique)</term>
<term>Électrolytes (analyse)</term>
<term>Études cas-témoins</term>
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<term>Immunoglobulin A, Secretory</term>
<term>Salivary Proteins and Peptides</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Insulin</term>
<term>Tolbutamide</term>
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<term>Protéines et peptides salivaires</term>
<term>Électrolytes</term>
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<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Diabetes Mellitus, Type 1</term>
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<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Diabète</term>
<term>Diabète de type 1</term>
<term>Diabète de type 2</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Diabetes Mellitus</term>
<term>Diabetes Mellitus, Type 1</term>
<term>Diabetes Mellitus, Type 2</term>
</keywords>
<keywords scheme="MESH" qualifier="secretion" xml:lang="en"><term>Parotid Gland</term>
<term>Saliva</term>
</keywords>
<keywords scheme="MESH" qualifier="sécrétion" xml:lang="fr"><term>Glande parotide</term>
<term>Salive</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Diabetes Mellitus</term>
<term>Diabetes Mellitus, Type 2</term>
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<term>Tolbutamide</term>
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<keywords scheme="MESH" xml:lang="en"><term>African Continental Ancestry Group</term>
<term>Aged</term>
<term>Analysis of Variance</term>
<term>Case-Control Studies</term>
<term>Diet Therapy</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mouth, Edentulous</term>
<term>Salivation</term>
<term>Secretory Rate</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Analyse de variance</term>
<term>Baltimore</term>
<term>Bouche édentée</term>
<term>Diabète</term>
<term>Diabète de type 2</term>
<term>Diétothérapie</term>
<term>Débit sécrétoire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Population d'origine africaine</term>
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<front><div type="abstract" xml:lang="en">This study examined parotid salivary flow rate and composition in three groups of differently treated diabetics and a control group of non-diabetics. The study population was composed of edentulous African-Americans at least 65 years of age. Group A was the control, Group B insulin-dependent (Regular Iletin, U-100 qd.), Group C controlled by oral medication (Tolbutamide, 500 mg qd.), and Group D was diet controlled. All diabetic patients had serum glucose values under 250 mg/dl. Salivary flow rates, secretory IgA, electrolytes (Na+, Cl-, K+, Ca++) and total protein concentrations were evaluated. The results showed no significant differences between groups with respect to salivary flow rates, electrolytes and IgA concentrations. Additionally, all diabetic groups demonstrated a significantly lower salivary total protein concentration when compared to the controls. There appears to be no evident decrease in salivary flow rate in these three differently controlled diabetic groups compared with healthy non-diabetics.</div>
</front>
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<DateCompleted><Year>1994</Year>
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<Title>Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology</Title>
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<ArticleTitle>Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.</ArticleTitle>
<Pagination><MedlinePgn>277-9</MedlinePgn>
</Pagination>
<Abstract><AbstractText>This study examined parotid salivary flow rate and composition in three groups of differently treated diabetics and a control group of non-diabetics. The study population was composed of edentulous African-Americans at least 65 years of age. Group A was the control, Group B insulin-dependent (Regular Iletin, U-100 qd.), Group C controlled by oral medication (Tolbutamide, 500 mg qd.), and Group D was diet controlled. All diabetic patients had serum glucose values under 250 mg/dl. Salivary flow rates, secretory IgA, electrolytes (Na+, Cl-, K+, Ca++) and total protein concentrations were evaluated. The results showed no significant differences between groups with respect to salivary flow rates, electrolytes and IgA concentrations. Additionally, all diabetic groups demonstrated a significantly lower salivary total protein concentration when compared to the controls. There appears to be no evident decrease in salivary flow rate in these three differently controlled diabetic groups compared with healthy non-diabetics.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Streckfus</LastName>
<ForeName>C F</ForeName>
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<AffiliationInfo><Affiliation>Epidemiology and Oral Disease Prevention Program, National Institute of Dental Research, NIH, Bethesda, Md 20892.</Affiliation>
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<Author ValidYN="Y"><LastName>Marcus</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
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<Initials>S</Initials>
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<ForeName>R S</ForeName>
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<ForeName>G</ForeName>
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<Author ValidYN="Y"><LastName>Brown</LastName>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
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<NameOfSubstance UI="D007071">Immunoglobulin A, Secretory</NameOfSubstance>
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<CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>J Oral Pathol Med 1994 Nov;23(10):468</RefSource>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D044383" MajorTopicYN="Y">African Continental Ancestry Group</DescriptorName>
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<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D000704" MajorTopicYN="N">Analysis of Variance</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015142" MajorTopicYN="N" Type="Geographic">Baltimore</DescriptorName>
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<MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName>
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<MeshHeading><DescriptorName UI="D003920" MajorTopicYN="N">Diabetes Mellitus</DescriptorName>
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<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
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<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
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<MeshHeading><DescriptorName UI="D004573" MajorTopicYN="N">Electrolytes</DescriptorName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D007071" MajorTopicYN="N">Immunoglobulin A, Secretory</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D009066" MajorTopicYN="N">Mouth, Edentulous</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010306" MajorTopicYN="N">Parotid Gland</DescriptorName>
<QualifierName UI="Q000557" MajorTopicYN="Y">secretion</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000557" MajorTopicYN="Y">secretion</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012471" MajorTopicYN="N">Salivary Proteins and Peptides</DescriptorName>
<QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012472" MajorTopicYN="N">Salivation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012636" MajorTopicYN="N">Secretory Rate</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014044" MajorTopicYN="N">Tolbutamide</DescriptorName>
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<tree><noCountry><name sortKey="Brown, R H" sort="Brown, R H" uniqKey="Brown R" first="R H" last="Brown">R H Brown</name>
<name sortKey="Brown, R S" sort="Brown, R S" uniqKey="Brown R" first="R S" last="Brown">R S Brown</name>
<name sortKey="Cherry Peppers, G" sort="Cherry Peppers, G" uniqKey="Cherry Peppers G" first="G" last="Cherry-Peppers">G. Cherry-Peppers</name>
<name sortKey="Marcus, S" sort="Marcus, S" uniqKey="Marcus S" first="S" last="Marcus">S. Marcus</name>
<name sortKey="Streckfus, C F" sort="Streckfus, C F" uniqKey="Streckfus C" first="C F" last="Streckfus">C F Streckfus</name>
<name sortKey="Welsh, S" sort="Welsh, S" uniqKey="Welsh S" first="S" last="Welsh">S. Welsh</name>
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