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Effectiveness of Hexetidine 0.1% in Eliminating Candida albicans Colonizing Dentures: A Randomized Clinical In Vivo Study

Identifieur interne : 005D94 ( Ncbi/Checkpoint ); précédent : 005D93; suivant : 005D95

Effectiveness of Hexetidine 0.1% in Eliminating Candida albicans Colonizing Dentures: A Randomized Clinical In Vivo Study

Auteurs : Georges Aoun [Liban] ; Ibrahim Nasseh [Liban] ; Maria Saadeh [Liban] ; Antoine Cassia [Liban] ; Antoine Berberi [Liban]

Source :

RBID : PMC:4516077

Abstract

Background:

Effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating C. albicans colonizing dentures.

Materials and Methods:

A total of 40 denture wearers (18 men, 22 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 groups, 1 test, and 1 control. The dentures of the test group were treated by immersion in hexetidine 0.1% while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.

Results:

Reduction in the number of colony-forming units (CFU) of C. albicans after immersion of the dentures with hexetidine 0.1% was evaluated compared to those of the control group.

Conclusion:

Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days.


Url:
PubMed: 26225095
PubMed Central: 4516077


Affiliations:


Links toward previous steps (curation, corpus...)


Links to Exploration step

PMC:4516077

Le document en format XML

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<p>Effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating
<italic>C. albicans</italic>
colonizing dentures.</p>
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<title>Materials and Methods:</title>
<p>A total of 40 denture wearers (18 men, 22 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 groups, 1 test, and 1 control. The dentures of the test group were treated by immersion in hexetidine 0.1% while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.</p>
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<p>Reduction in the number of colony-forming units (CFU) of
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after immersion of the dentures with hexetidine 0.1% was evaluated compared to those of the control group.</p>
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