Effectiveness of Hexetidine 0.1% in Eliminating Candida albicans Colonizing Dentures: A Randomized Clinical In Vivo Study
Identifieur interne : 005D94 ( Ncbi/Merge ); précédent : 005D93; suivant : 005D95Effectiveness of Hexetidine 0.1% in Eliminating Candida albicans Colonizing Dentures: A Randomized Clinical In Vivo Study
Auteurs : Georges Aoun [Liban] ; Ibrahim Nasseh [Liban] ; Maria Saadeh [Liban] ; Antoine Cassia [Liban] ; Antoine Berberi [Liban]Source :
- Journal of International Oral Health : JIOH [ 0976-7428 ] ; 2015.
Abstract
Effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating
A total of 40 denture wearers (18 men, 22 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 groups, 1 test, and 1 control. The dentures of the test group were treated by immersion in hexetidine 0.1% while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.
Reduction in the number of colony-forming units (CFU) of
Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days.
Url:
PubMed: 26225095
PubMed Central: 4516077
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Colonizing Dentures: A Randomized Clinical <italic>In Vivo</italic>
Study</title>
<author><name sortKey="Aoun, Georges" sort="Aoun, Georges" uniqKey="Aoun G" first="Georges" last="Aoun">Georges Aoun</name>
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<author><name sortKey="Berberi, Antoine" sort="Berberi, Antoine" uniqKey="Berberi A" first="Antoine" last="Berberi">Antoine Berberi</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effectiveness of Hexetidine 0.1% in Eliminating <italic>Candida albicans</italic>
Colonizing Dentures: A Randomized Clinical <italic>In Vivo</italic>
Study</title>
<author><name sortKey="Aoun, Georges" sort="Aoun, Georges" uniqKey="Aoun G" first="Georges" last="Aoun">Georges Aoun</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Assistant Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Assistant Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nasseh, Ibrahim" sort="Nasseh, Ibrahim" uniqKey="Nasseh I" first="Ibrahim" last="Nasseh">Ibrahim Nasseh</name>
<affiliation wicri:level="1"><nlm:aff id="aff2">Professor, Department of Oral and Maxillofacial Imaging, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Professor, Department of Oral and Maxillofacial Imaging, School of Dentistry, Lebanese University, Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
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<author><name sortKey="Saadeh, Maria" sort="Saadeh, Maria" uniqKey="Saadeh M" first="Maria" last="Saadeh">Maria Saadeh</name>
<affiliation wicri:level="1"><nlm:aff id="aff3">Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff4">Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut</wicri:regionArea>
<wicri:noRegion>American University of Beirut</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cassia, Antoine" sort="Cassia, Antoine" uniqKey="Cassia A" first="Antoine" last="Cassia">Antoine Cassia</name>
<affiliation wicri:level="1"><nlm:aff id="aff5">Associate Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Associate Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
</affiliation>
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<author><name sortKey="Berberi, Antoine" sort="Berberi, Antoine" uniqKey="Berberi A" first="Antoine" last="Berberi">Antoine Berberi</name>
<affiliation wicri:level="1"><nlm:aff id="aff6">Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
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<series><title level="j">Journal of International Oral Health : JIOH</title>
<idno type="ISSN">0976-7428</idno>
<idno type="eISSN">0976-1799</idno>
<imprint><date when="2015">2015</date>
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<front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background:</title>
<p>Effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating <italic>C. albicans</italic>
colonizing dentures.</p>
</sec>
<sec id="st2"><title>Materials and Methods:</title>
<p>A total of 40 denture wearers (18 men, 22 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 groups, 1 test, and 1 control. The dentures of the test group were treated by immersion in hexetidine 0.1% while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.</p>
</sec>
<sec id="st3"><title>Results:</title>
<p>Reduction in the number of colony-forming units (CFU) of <italic>C. albicans</italic>
after immersion of the dentures with hexetidine 0.1% was evaluated compared to those of the control group.</p>
</sec>
<sec id="st4"><title>Conclusion:</title>
<p>Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days.</p>
</sec>
</div>
</front>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Int Oral Health</journal-id>
<journal-id journal-id-type="iso-abbrev">J Int Oral Health</journal-id>
<journal-id journal-id-type="publisher-id">JIOH</journal-id>
<journal-title-group><journal-title>Journal of International Oral Health : JIOH</journal-title>
</journal-title-group>
<issn pub-type="ppub">0976-7428</issn>
<issn pub-type="epub">0976-1799</issn>
<publisher><publisher-name>Dentmedpub Research and Printing Co</publisher-name>
<publisher-loc>India</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26225095</article-id>
<article-id pub-id-type="pmc">4516077</article-id>
<article-id pub-id-type="publisher-id">JIOH-7-1</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Research</subject>
</subj-group>
</article-categories>
<title-group><article-title>Effectiveness of Hexetidine 0.1% in Eliminating <italic>Candida albicans</italic>
Colonizing Dentures: A Randomized Clinical <italic>In Vivo</italic>
Study</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Aoun</surname>
<given-names>Georges</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nasseh</surname>
<given-names>Ibrahim</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Saadeh</surname>
<given-names>Maria</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Cassia</surname>
<given-names>Antoine</given-names>
</name>
<xref ref-type="aff" rid="aff5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Berberi</surname>
<given-names>Antoine</given-names>
</name>
<xref ref-type="aff" rid="aff6">6</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
</contrib-group>
<aff id="aff1"><label>1</label>
Assistant Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon</aff>
<aff id="aff2"><label>2</label>
Professor, Department of Oral and Maxillofacial Imaging, School of Dentistry, Lebanese University, Beirut, Lebanon</aff>
<aff id="aff3"><label>3</label>
Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut, Lebanon</aff>
<aff id="aff4"><label>4</label>
Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut, Lebanon</aff>
<aff id="aff5"><label>5</label>
Associate Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon</aff>
<aff id="aff6"><label>6</label>
Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon</aff>
<author-notes><corresp id="cor1"><bold><italic>Correspondence:</italic>
</bold>
Dr. Berberi A. Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon. Email: <email xlink:href="anberberi@gmail.com">anberberi@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><year>2015</year>
</pub-date>
<volume>7</volume>
<issue>Suppl 1</issue>
<fpage>1</fpage>
<lpage>4</lpage>
<history><date date-type="received"><day>28</day>
<month>1</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>20</day>
<month>4</month>
<year>2015</year>
</date>
</history>
<permissions><copyright-statement>Copyright: © Journal of International Oral Health</copyright-statement>
<copyright-year>2015</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><sec id="st1"><title>Background:</title>
<p>Effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating <italic>C. albicans</italic>
colonizing dentures.</p>
</sec>
<sec id="st2"><title>Materials and Methods:</title>
<p>A total of 40 denture wearers (18 men, 22 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 groups, 1 test, and 1 control. The dentures of the test group were treated by immersion in hexetidine 0.1% while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.</p>
</sec>
<sec id="st3"><title>Results:</title>
<p>Reduction in the number of colony-forming units (CFU) of <italic>C. albicans</italic>
after immersion of the dentures with hexetidine 0.1% was evaluated compared to those of the control group.</p>
</sec>
<sec id="st4"><title>Conclusion:</title>
<p>Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days.</p>
</sec>
</abstract>
<kwd-group><kwd><italic>Candida albicans</italic>
</kwd>
<kwd>denture stomatitis</kwd>
<kwd>hexetidine</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Liban</li>
</country>
</list>
<tree><country name="Liban"><noRegion><name sortKey="Aoun, Georges" sort="Aoun, Georges" uniqKey="Aoun G" first="Georges" last="Aoun">Georges Aoun</name>
</noRegion>
<name sortKey="Berberi, Antoine" sort="Berberi, Antoine" uniqKey="Berberi A" first="Antoine" last="Berberi">Antoine Berberi</name>
<name sortKey="Cassia, Antoine" sort="Cassia, Antoine" uniqKey="Cassia A" first="Antoine" last="Cassia">Antoine Cassia</name>
<name sortKey="Nasseh, Ibrahim" sort="Nasseh, Ibrahim" uniqKey="Nasseh I" first="Ibrahim" last="Nasseh">Ibrahim Nasseh</name>
<name sortKey="Saadeh, Maria" sort="Saadeh, Maria" uniqKey="Saadeh M" first="Maria" last="Saadeh">Maria Saadeh</name>
<name sortKey="Saadeh, Maria" sort="Saadeh, Maria" uniqKey="Saadeh M" first="Maria" last="Saadeh">Maria Saadeh</name>
</country>
</tree>
</affiliations>
</record>
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