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Relationship of periodontal disease and edentulism to stroke/TIA.

Identifieur interne : 001127 ( Ncbi/Checkpoint ); précédent : 001126; suivant : 001128

Relationship of periodontal disease and edentulism to stroke/TIA.

Auteurs : J R Elter [États-Unis] ; S. Offenbacher ; J F Toole ; J D Beck

Source :

RBID : pubmed:14630902

Descripteurs français

English descriptors

Abstract

Periodontitis has been shown to increase the systemic inflammatory response, which has been implicated in atherosclerosis and cerebrovascular events. We hypothesized an association between periodontitis or edentulism and Stroke/TIA in the ARIC Study. Data on 9415 dentate and 1491 edentulous adults included demographics, cardiovascular outcomes, lifestyle, laboratory measures, and, for 6436 of the dentate, a dental examination. The dependent variable was Stroke/TIA, and the exposure was extent (%) of attachment level 3+ millimeters (AL). Quartiles of AL and edentulism were compared for Stroke/TIA using odds ratios (OR) and 95% confidence intervals (CI), and confounders were controlled by logistic regression. Stroke/TIA was prevalent in 13.5% of periodontal examinees, 15.6% of dentate non-examinees, and 22.5% of edentulous persons. The highest quartile of AL (OR 1.3, CI 1.02-1.7) and edentulism (OR 1.4, CI 1.5-2.0) were associated with Stroke/TIA.

DOI: 10.1177/154405910308201212
PubMed: 14630902


Affiliations:


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pubmed:14630902

Le document en format XML

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<term>Coronary Disease (epidemiology)</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Ischemic Attack, Transient (epidemiology)</term>
<term>Life Style</term>
<term>Logistic Models</term>
<term>Male</term>
<term>Mouth, Edentulous (epidemiology)</term>
<term>Odds Ratio</term>
<term>Periodontal Attachment Loss (epidemiology)</term>
<term>Periodontal Diseases (epidemiology)</term>
<term>Prevalence</term>
<term>Risk Factors</term>
<term>Sex Factors</term>
<term>Smoking (epidemiology)</term>
<term>Stroke (epidemiology)</term>
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<term>Accident vasculaire cérébral (épidémiologie)</term>
<term>Adulte</term>
<term>Bouche édentée (épidémiologie)</term>
<term>Facteurs de confusion (épidémiologie)</term>
<term>Facteurs de risque</term>
<term>Facteurs sexuels</term>
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<term>Logistic Models</term>
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<term>Sex Factors</term>
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<term>Facteurs sexuels</term>
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<term>Intervalles de confiance</term>
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<div type="abstract" xml:lang="en">Periodontitis has been shown to increase the systemic inflammatory response, which has been implicated in atherosclerosis and cerebrovascular events. We hypothesized an association between periodontitis or edentulism and Stroke/TIA in the ARIC Study. Data on 9415 dentate and 1491 edentulous adults included demographics, cardiovascular outcomes, lifestyle, laboratory measures, and, for 6436 of the dentate, a dental examination. The dependent variable was Stroke/TIA, and the exposure was extent (%) of attachment level 3+ millimeters (AL). Quartiles of AL and edentulism were compared for Stroke/TIA using odds ratios (OR) and 95% confidence intervals (CI), and confounders were controlled by logistic regression. Stroke/TIA was prevalent in 13.5% of periodontal examinees, 15.6% of dentate non-examinees, and 22.5% of edentulous persons. The highest quartile of AL (OR 1.3, CI 1.02-1.7) and edentulism (OR 1.4, CI 1.5-2.0) were associated with Stroke/TIA.</div>
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