Relationship of periodontal disease and edentulism to stroke/TIA.
Identifieur interne : 001127 ( Ncbi/Merge ); précédent : 001126; suivant : 001128Relationship of periodontal disease and edentulism to stroke/TIA.
Auteurs : J R Elter [États-Unis] ; S. Offenbacher ; J F Toole ; J D BeckSource :
- Journal of dental research [ 0022-0345 ] ; 2003.
Descripteurs français
- KwdFr :
- Accident ischémique transitoire (épidémiologie), Accident vasculaire cérébral (épidémiologie), Adulte, Bouche édentée (épidémiologie), Facteurs de confusion (épidémiologie), Facteurs de risque, Facteurs sexuels, Femelle, Humains, Intervalles de confiance, Maladie coronarienne (épidémiologie), Maladies parodontales (épidémiologie), Mode de vie, Modèles logistiques, Mâle, Odds ratio, Perte d'attache parodontale (épidémiologie), Prévalence, Tabagisme (épidémiologie), États-Unis d'Amérique (épidémiologie), Études transversales.
- MESH :
- épidémiologie : Accident ischémique transitoire, Accident vasculaire cérébral, Bouche édentée, Maladie coronarienne, Maladies parodontales, Perte d'attache parodontale, Tabagisme, États-Unis d'Amérique.
- Adulte, Facteurs de confusion (épidémiologie), Facteurs de risque, Facteurs sexuels, Femelle, Humains, Intervalles de confiance, Mode de vie, Modèles logistiques, Mâle, Odds ratio, Prévalence, Études transversales.
- Wicri :
- geographic : États-Unis.
English descriptors
- KwdEn :
- Adult, Confidence Intervals, Confounding Factors (Epidemiology), Coronary Disease (epidemiology), Cross-Sectional Studies, Female, Humans, Ischemic Attack, Transient (epidemiology), Life Style, Logistic Models, Male, Mouth, Edentulous (epidemiology), Odds Ratio, Periodontal Attachment Loss (epidemiology), Periodontal Diseases (epidemiology), Prevalence, Risk Factors, Sex Factors, Smoking (epidemiology), Stroke (epidemiology), United States (epidemiology).
- MESH :
- geographic , epidemiology : United States.
- epidemiology : Coronary Disease, Ischemic Attack, Transient, Mouth, Edentulous, Periodontal Attachment Loss, Periodontal Diseases, Smoking, Stroke.
- Adult, Confidence Intervals, Confounding Factors (Epidemiology), Cross-Sectional Studies, Female, Humans, Life Style, Logistic Models, Male, Odds Ratio, Prevalence, Risk Factors, Sex Factors.
Abstract
Periodontitis has been shown to increase the systemic inflammatory response, which has been implicated in atherosclerosis and cerebrovascular events. We hypothesized an association between periodontitis or edentulism and Stroke/TIA in the ARIC Study. Data on 9415 dentate and 1491 edentulous adults included demographics, cardiovascular outcomes, lifestyle, laboratory measures, and, for 6436 of the dentate, a dental examination. The dependent variable was Stroke/TIA, and the exposure was extent (%) of attachment level 3+ millimeters (AL). Quartiles of AL and edentulism were compared for Stroke/TIA using odds ratios (OR) and 95% confidence intervals (CI), and confounders were controlled by logistic regression. Stroke/TIA was prevalent in 13.5% of periodontal examinees, 15.6% of dentate non-examinees, and 22.5% of edentulous persons. The highest quartile of AL (OR 1.3, CI 1.02-1.7) and edentulism (OR 1.4, CI 1.5-2.0) were associated with Stroke/TIA.
DOI: 10.1177/154405910308201212
PubMed: 14630902
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pubmed:14630902Le document en format XML
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<front><div type="abstract" xml:lang="en">Periodontitis has been shown to increase the systemic inflammatory response, which has been implicated in atherosclerosis and cerebrovascular events. We hypothesized an association between periodontitis or edentulism and Stroke/TIA in the ARIC Study. Data on 9415 dentate and 1491 edentulous adults included demographics, cardiovascular outcomes, lifestyle, laboratory measures, and, for 6436 of the dentate, a dental examination. The dependent variable was Stroke/TIA, and the exposure was extent (%) of attachment level 3+ millimeters (AL). Quartiles of AL and edentulism were compared for Stroke/TIA using odds ratios (OR) and 95% confidence intervals (CI), and confounders were controlled by logistic regression. Stroke/TIA was prevalent in 13.5% of periodontal examinees, 15.6% of dentate non-examinees, and 22.5% of edentulous persons. The highest quartile of AL (OR 1.3, CI 1.02-1.7) and edentulism (OR 1.4, CI 1.5-2.0) were associated with Stroke/TIA.</div>
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