Studies of fluoride retention by oral soft tissues after the application of home-use topical fluorides.
Identifieur interne : 00B067 ( Main/Exploration ); précédent : 00B066; suivant : 00B068Studies of fluoride retention by oral soft tissues after the application of home-use topical fluorides.
Auteurs : D T Zero [États-Unis] ; R F Raubertas ; A M Pedersen ; J. Fu ; A L Hayes ; J D FeatherstoneSource :
- Journal of dental research [ 0022-0345 ] ; 1992.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Analyse de variance, Bouche édentée, Dentifrices, Débit sécrétoire, Femelle, Fluorures (métabolisme), Fluorures topiques (administration et posologie), Fluorures topiques (pharmacocinétique), Gels, Humains, Joue, Langue, Muqueuse de la bouche (métabolisme), Mâle, Plancher de la bouche, Salive (), Salive (sécrétion).
- MESH :
- administration et posologie : Fluorures topiques.
- métabolisme : Fluorures, Muqueuse de la bouche.
- pharmacocinétique : Fluorures topiques.
- sécrétion : Salive.
- Adulte d'âge moyen, Analyse de variance, Bouche édentée, Dentifrices, Débit sécrétoire, Femelle, Gels, Humains, Joue, Langue, Mâle, Plancher de la bouche, Salive.
English descriptors
- KwdEn :
- Analysis of Variance, Cheek, Dentifrices, Female, Fluorides (metabolism), Fluorides, Topical (administration & dosage), Fluorides, Topical (pharmacokinetics), Gels, Humans, Male, Middle Aged, Mouth Floor, Mouth Mucosa (metabolism), Mouth, Edentulous, Saliva (chemistry), Saliva (secretion), Secretory Rate, Tongue.
- MESH :
- chemical , administration & dosage : Fluorides, Topical.
- chemical , metabolism : Fluorides.
- chemical , pharmacokinetics : Fluorides, Topical.
- chemical : Dentifrices, Gels.
- chemistry : Saliva.
- metabolism : Mouth Mucosa.
- secretion : Saliva.
- Analysis of Variance, Cheek, Female, Humans, Male, Middle Aged, Mouth Floor, Mouth, Edentulous, Secretory Rate, Tongue.
Abstract
Previous studies have focused on enamel and plaque as the primary sites of fluoride (F) retention in the mouth. The present study was undertaken to evaluate the role of oral soft tissue as a site of F retention by comparing an edentulous subject panel (n = 9) with a fully dentate panel (n = 10). Unstimulated whole saliva samples were collected by having subjects pool saliva for two min. Samples were collected over a 24-hour period after application of a placebo dentifrice (PD; 0.4 ppm F), fluoride dentifrice (FD; 1100 ppm F), fluoride rinse (FR; 226 ppm F), or fluoride gel (FG; 5000 ppm F) delivered in custom trays. There was no statistically significant difference in salivary flow rate between the two panels for any of the treatments. The edentulous panel had higher salivary F levels than the dentate panel, which reached statistical significance (p less than 0.05) for the FD and FG treatments. In a separate study involving the same treatments, F levels at specific soft-tissue sites were measured over a one-hour period by use of absorbent discs placed in different soft-tissue areas of the mouth. The tongue and lower posterior vestibule retained the highest F levels, followed by the upper posterior buccal vestibule and upper anterior labial vestibule, with the lowest F levels retained in the lower anterior vestibule and the floor of the mouth. There was a strong-to-moderate correlation between whole saliva F concentration and F levels at specific soft-tissue sites. This study establishes the importance of oral soft tissue as the major site of F retention in the mouth.
DOI: 10.1177/00220345920710090101
PubMed: 1522285
Affiliations:
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Le document en format XML
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Fu</name></author><author><name sortKey="Hayes, A L" sort="Hayes, A L" uniqKey="Hayes A" first="A L" last="Hayes">A L Hayes</name></author><author><name sortKey="Featherstone, J D" sort="Featherstone, J D" uniqKey="Featherstone J" first="J D" last="Featherstone">J D Featherstone</name></author></analytic><series><title level="j">Journal of dental research</title><idno type="ISSN">0022-0345</idno><imprint><date when="1992" type="published">1992</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Analysis of Variance</term><term>Cheek</term><term>Dentifrices</term><term>Female</term><term>Fluorides (metabolism)</term><term>Fluorides, Topical (administration & dosage)</term><term>Fluorides, Topical (pharmacokinetics)</term><term>Gels</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mouth Floor</term><term>Mouth Mucosa (metabolism)</term><term>Mouth, Edentulous</term><term>Saliva (chemistry)</term><term>Saliva (secretion)</term><term>Secretory Rate</term><term>Tongue</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Analyse de variance</term><term>Bouche édentée</term><term>Dentifrices</term><term>Débit sécrétoire</term><term>Femelle</term><term>Fluorures (métabolisme)</term><term>Fluorures topiques (administration et posologie)</term><term>Fluorures topiques (pharmacocinétique)</term><term>Gels</term><term>Humains</term><term>Joue</term><term>Langue</term><term>Muqueuse de la bouche (métabolisme)</term><term>Mâle</term><term>Plancher de la bouche</term><term>Salive ()</term><term>Salive (sécrétion)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Fluorides, Topical</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Fluorides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Fluorides, Topical</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Dentifrices</term><term>Gels</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Fluorures topiques</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Mouth Mucosa</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Fluorures</term><term>Muqueuse de la bouche</term></keywords><keywords scheme="MESH" qualifier="pharmacocinétique" xml:lang="fr"><term>Fluorures topiques</term></keywords><keywords scheme="MESH" qualifier="secretion" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="sécrétion" xml:lang="fr"><term>Salive</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Analysis of Variance</term><term>Cheek</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mouth Floor</term><term>Mouth, Edentulous</term><term>Secretory Rate</term><term>Tongue</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Analyse de variance</term><term>Bouche édentée</term><term>Dentifrices</term><term>Débit sécrétoire</term><term>Femelle</term><term>Gels</term><term>Humains</term><term>Joue</term><term>Langue</term><term>Mâle</term><term>Plancher de la bouche</term><term>Salive</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Previous studies have focused on enamel and plaque as the primary sites of fluoride (F) retention in the mouth. The present study was undertaken to evaluate the role of oral soft tissue as a site of F retention by comparing an edentulous subject panel (n = 9) with a fully dentate panel (n = 10). Unstimulated whole saliva samples were collected by having subjects pool saliva for two min. Samples were collected over a 24-hour period after application of a placebo dentifrice (PD; 0.4 ppm F), fluoride dentifrice (FD; 1100 ppm F), fluoride rinse (FR; 226 ppm F), or fluoride gel (FG; 5000 ppm F) delivered in custom trays. There was no statistically significant difference in salivary flow rate between the two panels for any of the treatments. The edentulous panel had higher salivary F levels than the dentate panel, which reached statistical significance (p less than 0.05) for the FD and FG treatments. In a separate study involving the same treatments, F levels at specific soft-tissue sites were measured over a one-hour period by use of absorbent discs placed in different soft-tissue areas of the mouth. The tongue and lower posterior vestibule retained the highest F levels, followed by the upper posterior buccal vestibule and upper anterior labial vestibule, with the lowest F levels retained in the lower anterior vestibule and the floor of the mouth. There was a strong-to-moderate correlation between whole saliva F concentration and F levels at specific soft-tissue sites. This study establishes the importance of oral soft tissue as the major site of F retention in the mouth.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><noCountry><name sortKey="Featherstone, J D" sort="Featherstone, J D" uniqKey="Featherstone J" first="J D" last="Featherstone">J D Featherstone</name><name sortKey="Fu, J" sort="Fu, J" uniqKey="Fu J" first="J" last="Fu">J. Fu</name><name sortKey="Hayes, A L" sort="Hayes, A L" uniqKey="Hayes A" first="A L" last="Hayes">A L Hayes</name><name sortKey="Pedersen, A M" sort="Pedersen, A M" uniqKey="Pedersen A" first="A M" last="Pedersen">A M Pedersen</name><name sortKey="Raubertas, R F" sort="Raubertas, R F" uniqKey="Raubertas R" first="R F" last="Raubertas">R F Raubertas</name></noCountry><country name="États-Unis"><region name="État de New York"><name sortKey="Zero, D T" sort="Zero, D T" uniqKey="Zero D" first="D T" last="Zero">D T Zero</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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