Studies of fluoride retention by oral soft tissues after the application of home-use topical fluorides.
Identifieur interne : 004739 ( PubMed/Corpus ); précédent : 004738; suivant : 004740Studies of fluoride retention by oral soft tissues after the application of home-use topical fluorides.
Auteurs : D T Zero ; R F Raubertas ; A M Pedersen ; J. Fu ; A L Hayes ; J D FeatherstoneSource :
- Journal of dental research [ 0022-0345 ] ; 1992.
English descriptors
- KwdEn :
- Analysis of Variance, Cheek, Dentifrices, Female, Fluorides (metabolism), Fluorides, Topical (administration & dosage), Fluorides, Topical (pharmacokinetics), Gels, Humans, Male, Middle Aged, Mouth Floor, Mouth Mucosa (metabolism), Mouth, Edentulous, Saliva (chemistry), Saliva (secretion), Secretory Rate, Tongue.
- MESH :
- chemical , administration & dosage : Fluorides, Topical.
- chemical , metabolism : Fluorides.
- chemical , pharmacokinetics : Fluorides, Topical.
- chemical : Dentifrices, Gels.
- chemistry : Saliva.
- metabolism : Mouth Mucosa.
- secretion : Saliva.
- Analysis of Variance, Cheek, Female, Humans, Male, Middle Aged, Mouth Floor, Mouth, Edentulous, Secretory Rate, Tongue.
Abstract
Previous studies have focused on enamel and plaque as the primary sites of fluoride (F) retention in the mouth. The present study was undertaken to evaluate the role of oral soft tissue as a site of F retention by comparing an edentulous subject panel (n = 9) with a fully dentate panel (n = 10). Unstimulated whole saliva samples were collected by having subjects pool saliva for two min. Samples were collected over a 24-hour period after application of a placebo dentifrice (PD; 0.4 ppm F), fluoride dentifrice (FD; 1100 ppm F), fluoride rinse (FR; 226 ppm F), or fluoride gel (FG; 5000 ppm F) delivered in custom trays. There was no statistically significant difference in salivary flow rate between the two panels for any of the treatments. The edentulous panel had higher salivary F levels than the dentate panel, which reached statistical significance (p less than 0.05) for the FD and FG treatments. In a separate study involving the same treatments, F levels at specific soft-tissue sites were measured over a one-hour period by use of absorbent discs placed in different soft-tissue areas of the mouth. The tongue and lower posterior vestibule retained the highest F levels, followed by the upper posterior buccal vestibule and upper anterior labial vestibule, with the lowest F levels retained in the lower anterior vestibule and the floor of the mouth. There was a strong-to-moderate correlation between whole saliva F concentration and F levels at specific soft-tissue sites. This study establishes the importance of oral soft tissue as the major site of F retention in the mouth.
DOI: 10.1177/00220345920710090101
PubMed: 1522285
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Studies of fluoride retention by oral soft tissues after the application of home-use topical fluorides.</title><author><name sortKey="Zero, D T" sort="Zero, D T" uniqKey="Zero D" first="D T" last="Zero">D T Zero</name><affiliation><nlm:affiliation>Department of Oral Sciences, Eastman Dental Center, Rochester, New York 14620.</nlm:affiliation></affiliation></author><author><name sortKey="Raubertas, R F" sort="Raubertas, R F" uniqKey="Raubertas R" first="R F" last="Raubertas">R F Raubertas</name></author><author><name sortKey="Pedersen, A M" sort="Pedersen, A M" uniqKey="Pedersen A" first="A M" last="Pedersen">A M Pedersen</name></author><author><name sortKey="Fu, J" sort="Fu, J" uniqKey="Fu J" first="J" last="Fu">J. Fu</name></author><author><name sortKey="Hayes, A L" sort="Hayes, A L" uniqKey="Hayes A" first="A L" last="Hayes">A L Hayes</name></author><author><name sortKey="Featherstone, J D" sort="Featherstone, J D" uniqKey="Featherstone J" first="J D" last="Featherstone">J D Featherstone</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1992">1992</date><idno type="RBID">pubmed:1522285</idno><idno type="pmid">1522285</idno><idno type="doi">10.1177/00220345920710090101</idno><idno type="wicri:Area/PubMed/Corpus">004739</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004739</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Studies of fluoride retention by oral soft tissues after the application of home-use topical fluorides.</title><author><name sortKey="Zero, D T" sort="Zero, D T" uniqKey="Zero D" first="D T" last="Zero">D T Zero</name><affiliation><nlm:affiliation>Department of Oral Sciences, Eastman Dental Center, Rochester, New York 14620.</nlm:affiliation></affiliation></author><author><name sortKey="Raubertas, R F" sort="Raubertas, R F" uniqKey="Raubertas R" first="R F" last="Raubertas">R F Raubertas</name></author><author><name sortKey="Pedersen, A M" sort="Pedersen, A M" uniqKey="Pedersen A" first="A M" last="Pedersen">A M Pedersen</name></author><author><name sortKey="Fu, J" sort="Fu, J" uniqKey="Fu J" first="J" last="Fu">J. Fu</name></author><author><name sortKey="Hayes, A L" sort="Hayes, A L" uniqKey="Hayes A" first="A L" last="Hayes">A L Hayes</name></author><author><name sortKey="Featherstone, J D" sort="Featherstone, J D" uniqKey="Featherstone J" first="J D" last="Featherstone">J D Featherstone</name></author></analytic><series><title level="j">Journal of dental research</title><idno type="ISSN">0022-0345</idno><imprint><date when="1992" type="published">1992</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Analysis of Variance</term><term>Cheek</term><term>Dentifrices</term><term>Female</term><term>Fluorides (metabolism)</term><term>Fluorides, Topical (administration & dosage)</term><term>Fluorides, Topical (pharmacokinetics)</term><term>Gels</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mouth Floor</term><term>Mouth Mucosa (metabolism)</term><term>Mouth, Edentulous</term><term>Saliva (chemistry)</term><term>Saliva (secretion)</term><term>Secretory Rate</term><term>Tongue</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Fluorides, Topical</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Fluorides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Fluorides, Topical</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Dentifrices</term><term>Gels</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Mouth Mucosa</term></keywords><keywords scheme="MESH" qualifier="secretion" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Analysis of Variance</term><term>Cheek</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mouth Floor</term><term>Mouth, Edentulous</term><term>Secretory Rate</term><term>Tongue</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Previous studies have focused on enamel and plaque as the primary sites of fluoride (F) retention in the mouth. The present study was undertaken to evaluate the role of oral soft tissue as a site of F retention by comparing an edentulous subject panel (n = 9) with a fully dentate panel (n = 10). Unstimulated whole saliva samples were collected by having subjects pool saliva for two min. Samples were collected over a 24-hour period after application of a placebo dentifrice (PD; 0.4 ppm F), fluoride dentifrice (FD; 1100 ppm F), fluoride rinse (FR; 226 ppm F), or fluoride gel (FG; 5000 ppm F) delivered in custom trays. There was no statistically significant difference in salivary flow rate between the two panels for any of the treatments. The edentulous panel had higher salivary F levels than the dentate panel, which reached statistical significance (p less than 0.05) for the FD and FG treatments. In a separate study involving the same treatments, F levels at specific soft-tissue sites were measured over a one-hour period by use of absorbent discs placed in different soft-tissue areas of the mouth. The tongue and lower posterior vestibule retained the highest F levels, followed by the upper posterior buccal vestibule and upper anterior labial vestibule, with the lowest F levels retained in the lower anterior vestibule and the floor of the mouth. There was a strong-to-moderate correlation between whole saliva F concentration and F levels at specific soft-tissue sites. This study establishes the importance of oral soft tissue as the major site of F retention in the mouth.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">1522285</PMID><DateCompleted><Year>1992</Year><Month>10</Month><Day>14</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>14</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-0345</ISSN><JournalIssue CitedMedium="Print"><Volume>71</Volume><Issue>9</Issue><PubDate><Year>1992</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Journal of dental research</Title><ISOAbbreviation>J. Dent. Res.</ISOAbbreviation></Journal><ArticleTitle>Studies of fluoride retention by oral soft tissues after the application of home-use topical fluorides.</ArticleTitle><Pagination><MedlinePgn>1546-52</MedlinePgn></Pagination><Abstract><AbstractText>Previous studies have focused on enamel and plaque as the primary sites of fluoride (F) retention in the mouth. The present study was undertaken to evaluate the role of oral soft tissue as a site of F retention by comparing an edentulous subject panel (n = 9) with a fully dentate panel (n = 10). Unstimulated whole saliva samples were collected by having subjects pool saliva for two min. Samples were collected over a 24-hour period after application of a placebo dentifrice (PD; 0.4 ppm F), fluoride dentifrice (FD; 1100 ppm F), fluoride rinse (FR; 226 ppm F), or fluoride gel (FG; 5000 ppm F) delivered in custom trays. There was no statistically significant difference in salivary flow rate between the two panels for any of the treatments. The edentulous panel had higher salivary F levels than the dentate panel, which reached statistical significance (p less than 0.05) for the FD and FG treatments. In a separate study involving the same treatments, F levels at specific soft-tissue sites were measured over a one-hour period by use of absorbent discs placed in different soft-tissue areas of the mouth. The tongue and lower posterior vestibule retained the highest F levels, followed by the upper posterior buccal vestibule and upper anterior labial vestibule, with the lowest F levels retained in the lower anterior vestibule and the floor of the mouth. There was a strong-to-moderate correlation between whole saliva F concentration and F levels at specific soft-tissue sites. This study establishes the importance of oral soft tissue as the major site of F retention in the mouth.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zero</LastName><ForeName>D T</ForeName><Initials>DT</Initials><AffiliationInfo><Affiliation>Department of Oral Sciences, Eastman Dental Center, Rochester, New York 14620.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raubertas</LastName><ForeName>R F</ForeName><Initials>RF</Initials></Author><Author ValidYN="Y"><LastName>Pedersen</LastName><ForeName>A M</ForeName><Initials>AM</Initials></Author><Author ValidYN="Y"><LastName>Fu</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Hayes</LastName><ForeName>A L</ForeName><Initials>AL</Initials></Author><Author ValidYN="Y"><LastName>Featherstone</LastName><ForeName>J D</ForeName><Initials>JD</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>DE-08577</GrantID><Acronym>DE</Acronym><Agency>NIDCR NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Dent Res</MedlineTA><NlmUniqueID>0354343</NlmUniqueID><ISSNLinking>0022-0345</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D003802">Dentifrices</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005460">Fluorides, Topical</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005782">Gels</NameOfSubstance></Chemical><Chemical><RegistryNumber>Q80VPU408O</RegistryNumber><NameOfSubstance UI="D005459">Fluorides</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>J Dent Res 1993 Jan;72(1):87</RefSource></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000704" MajorTopicYN="N">Analysis of Variance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002610" MajorTopicYN="N">Cheek</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003802" MajorTopicYN="N">Dentifrices</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005459" MajorTopicYN="N">Fluorides</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005460" MajorTopicYN="N">Fluorides, Topical</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005782" MajorTopicYN="N">Gels</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009060" MajorTopicYN="N">Mouth Floor</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009061" MajorTopicYN="N">Mouth Mucosa</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009066" MajorTopicYN="N">Mouth, Edentulous</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000557" MajorTopicYN="N">secretion</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012636" MajorTopicYN="N">Secretory Rate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014059" MajorTopicYN="N">Tongue</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1992</Year><Month>9</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1992</Year><Month>9</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1992</Year><Month>9</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">1522285</ArticleId><ArticleId IdType="doi">10.1177/00220345920710090101</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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