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Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: Preliminary results

Identifieur interne : 008613 ( Main/Exploration ); précédent : 008612; suivant : 008614

Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: Preliminary results

Auteurs : M. Robiony [Italie] ; F. Polini [Italie] ; F. Costa [Italie] ; M. Politi [Italie]

Source :

RBID : Pascal:02-0373844

Descripteurs français

English descriptors

Abstract

Purpose: The purpose of this study was to evaluate a new method of restoring severe atrophic mandible using platelet-rich plasma (PRP) during distraction osteogenesis. Materials and Methods: Since 1999, 2 men and 3 women with severe atrophy (Cawood and Howell classes V and VI) of a completely edentulous mandible have been treated with a novel distraction procedure. During the surgery, a mixture of autologous bone graft, harvested from the iliac crest, and an autologous platelet concentrate, obtained from platelet-rich plasma, filled the distraction gap. This mixture constituted an autologous bone-platelet gel that was used to create a useful bony scaffold for distraction regenerate. After a latency period of 15 days, a distraction run of 0.5 mm/d, and a 60-day period of consolidation, the distraction device was removed and implants were placed simultaneously. Results: In all treated patients, planned distraction height was achieved with a considerable enhancement of bony regeneration, and in all cases it was possible to place implants at a planned time. Conclusions: The combination of these recent and innovative regenerative methods seems to be effective in restoring the severe atrophic mandible.


Affiliations:


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Le document en format XML

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<term>Alveolar Bone Loss (surgery)</term>
<term>Alveolar Ridge Augmentation (methods)</term>
<term>Atrophy</term>
<term>Blood plasma</term>
<term>Bone</term>
<term>Bone Regeneration</term>
<term>Bone Transplantation</term>
<term>Combined treatment</term>
<term>Dental Implantation, Endosseous</term>
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<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Gels</term>
<term>Humains</term>
<term>Maladies mandibulaires ()</term>
<term>Mandibule ()</term>
<term>Mâchoire édentée ()</term>
<term>Mâle</term>
<term>Ostéogenèse par distraction ()</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Reconstruction de crête alvéolaire ()</term>
<term>Régénération osseuse</term>
<term>Résorption alvéolaire ()</term>
<term>Transfusion de plaquettes</term>
<term>Transplantation osseuse</term>
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<term>Alveolar Ridge Augmentation</term>
<term>Osteogenesis, Distraction</term>
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<term>Mandible</term>
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<term>Bone Regeneration</term>
<term>Bone Transplantation</term>
<term>Dental Implantation, Endosseous</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Adulte d'âge moyen</term>
<term>Atrophie</term>
<term>Femelle</term>
<term>Gels</term>
<term>Humains</term>
<term>Maladies mandibulaires</term>
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<term>Ostéogenèse par distraction</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Reconstruction de crête alvéolaire</term>
<term>Régénération osseuse</term>
<term>Résorption alvéolaire</term>
<term>Traitement</term>
<term>Ostéogenèse</term>
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<term>Restauration</term>
<term>Gel</term>
<term>Transfusion de plaquettes</term>
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<div type="abstract" xml:lang="en">Purpose: The purpose of this study was to evaluate a new method of restoring severe atrophic mandible using platelet-rich plasma (PRP) during distraction osteogenesis. Materials and Methods: Since 1999, 2 men and 3 women with severe atrophy (Cawood and Howell classes V and VI) of a completely edentulous mandible have been treated with a novel distraction procedure. During the surgery, a mixture of autologous bone graft, harvested from the iliac crest, and an autologous platelet concentrate, obtained from platelet-rich plasma, filled the distraction gap. This mixture constituted an autologous bone-platelet gel that was used to create a useful bony scaffold for distraction regenerate. After a latency period of 15 days, a distraction run of 0.5 mm/d, and a 60-day period of consolidation, the distraction device was removed and implants were placed simultaneously. Results: In all treated patients, planned distraction height was achieved with a considerable enhancement of bony regeneration, and in all cases it was possible to place implants at a planned time. Conclusions: The combination of these recent and innovative regenerative methods seems to be effective in restoring the severe atrophic mandible.</div>
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