Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: Preliminary results
Identifieur interne : 008613 ( Main/Exploration ); précédent : 008612; suivant : 008614Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: Preliminary results
Auteurs : M. Robiony [Italie] ; F. Polini [Italie] ; F. Costa [Italie] ; M. Politi [Italie]Source :
- Journal of oral and maxillofacial surgery [ 0278-2391 ] ; 2002.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Femelle, Gels, Humains, Maladies mandibulaires (), Mandibule (), Mâchoire édentée (), Mâle, Ostéogenèse par distraction (), Pose d'implant dentaire endo-osseux, Reconstruction de crête alvéolaire (), Régénération osseuse, Résorption alvéolaire (), Transfusion de plaquettes, Transplantation osseuse.
- Pascal (Inist)
- Adulte d'âge moyen, Atrophie, Femelle, Gels, Humains, Maladies mandibulaires, Mandibule, Mâchoire édentée, Mâle, Ostéogenèse par distraction, Pose d'implant dentaire endo-osseux, Reconstruction de crête alvéolaire, Régénération osseuse, Résorption alvéolaire, Traitement, Ostéogenèse, Distraction, Thrombocyte, Plasma sanguin, Os, Restauration, Gel, Transfusion de plaquettes, Transplantation osseuse, Voie locale, Stimulation, Formation, Traitement associé, Homme.
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Alveolar Bone Loss (surgery), Alveolar Ridge Augmentation (methods), Atrophy, Blood plasma, Bone, Bone Regeneration, Bone Transplantation, Combined treatment, Dental Implantation, Endosseous, Distraction, Female, Formation, Freeze, Gels, Human, Humans, Jaw, Edentulous (surgery), Local administration, Male, Mandible, Mandible (surgery), Mandibular Diseases (surgery), Middle Aged, Osteogenesis, Osteogenesis, Distraction (methods), Platelet, Platelet Transfusion, Restoration, Stimulation, Treatment.
- MESH :
- chemical : Gels.
- methods : Alveolar Ridge Augmentation, Osteogenesis, Distraction.
- surgery : Alveolar Bone Loss, Jaw, Edentulous, Mandible, Mandibular Diseases.
- Bone Regeneration, Bone Transplantation, Dental Implantation, Endosseous, Female, Humans, Male, Middle Aged, Platelet Transfusion.
Abstract
Purpose: The purpose of this study was to evaluate a new method of restoring severe atrophic mandible using platelet-rich plasma (PRP) during distraction osteogenesis. Materials and Methods: Since 1999, 2 men and 3 women with severe atrophy (Cawood and Howell classes V and VI) of a completely edentulous mandible have been treated with a novel distraction procedure. During the surgery, a mixture of autologous bone graft, harvested from the iliac crest, and an autologous platelet concentrate, obtained from platelet-rich plasma, filled the distraction gap. This mixture constituted an autologous bone-platelet gel that was used to create a useful bony scaffold for distraction regenerate. After a latency period of 15 days, a distraction run of 0.5 mm/d, and a 60-day period of consolidation, the distraction device was removed and implants were placed simultaneously. Results: In all treated patients, planned distraction height was achieved with a considerable enhancement of bony regeneration, and in all cases it was possible to place implants at a planned time. Conclusions: The combination of these recent and innovative regenerative methods seems to be effective in restoring the severe atrophic mandible.
Affiliations:
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Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alveolar Bone Loss (surgery)</term>
<term>Alveolar Ridge Augmentation (methods)</term>
<term>Atrophy</term>
<term>Blood plasma</term>
<term>Bone</term>
<term>Bone Regeneration</term>
<term>Bone Transplantation</term>
<term>Combined treatment</term>
<term>Dental Implantation, Endosseous</term>
<term>Distraction</term>
<term>Female</term>
<term>Formation</term>
<term>Freeze</term>
<term>Gels</term>
<term>Human</term>
<term>Humans</term>
<term>Jaw, Edentulous (surgery)</term>
<term>Local administration</term>
<term>Male</term>
<term>Mandible</term>
<term>Mandible (surgery)</term>
<term>Mandibular Diseases (surgery)</term>
<term>Middle Aged</term>
<term>Osteogenesis</term>
<term>Osteogenesis, Distraction (methods)</term>
<term>Platelet</term>
<term>Platelet Transfusion</term>
<term>Restoration</term>
<term>Stimulation</term>
<term>Treatment</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Gels</term>
<term>Humains</term>
<term>Maladies mandibulaires ()</term>
<term>Mandibule ()</term>
<term>Mâchoire édentée ()</term>
<term>Mâle</term>
<term>Ostéogenèse par distraction ()</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Reconstruction de crête alvéolaire ()</term>
<term>Régénération osseuse</term>
<term>Résorption alvéolaire ()</term>
<term>Transfusion de plaquettes</term>
<term>Transplantation osseuse</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Gels</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Alveolar Ridge Augmentation</term>
<term>Osteogenesis, Distraction</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Alveolar Bone Loss</term>
<term>Jaw, Edentulous</term>
<term>Mandible</term>
<term>Mandibular Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Bone Regeneration</term>
<term>Bone Transplantation</term>
<term>Dental Implantation, Endosseous</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Platelet Transfusion</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Atrophie</term>
<term>Femelle</term>
<term>Gels</term>
<term>Humains</term>
<term>Maladies mandibulaires</term>
<term>Mandibule</term>
<term>Mâchoire édentée</term>
<term>Mâle</term>
<term>Ostéogenèse par distraction</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Reconstruction de crête alvéolaire</term>
<term>Régénération osseuse</term>
<term>Résorption alvéolaire</term>
<term>Traitement</term>
<term>Ostéogenèse</term>
<term>Distraction</term>
<term>Thrombocyte</term>
<term>Plasma sanguin</term>
<term>Os</term>
<term>Restauration</term>
<term>Gel</term>
<term>Transfusion de plaquettes</term>
<term>Transplantation osseuse</term>
<term>Voie locale</term>
<term>Stimulation</term>
<term>Formation</term>
<term>Traitement associé</term>
<term>Homme</term>
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<front><div type="abstract" xml:lang="en">Purpose: The purpose of this study was to evaluate a new method of restoring severe atrophic mandible using platelet-rich plasma (PRP) during distraction osteogenesis. Materials and Methods: Since 1999, 2 men and 3 women with severe atrophy (Cawood and Howell classes V and VI) of a completely edentulous mandible have been treated with a novel distraction procedure. During the surgery, a mixture of autologous bone graft, harvested from the iliac crest, and an autologous platelet concentrate, obtained from platelet-rich plasma, filled the distraction gap. This mixture constituted an autologous bone-platelet gel that was used to create a useful bony scaffold for distraction regenerate. After a latency period of 15 days, a distraction run of 0.5 mm/d, and a 60-day period of consolidation, the distraction device was removed and implants were placed simultaneously. Results: In all treated patients, planned distraction height was achieved with a considerable enhancement of bony regeneration, and in all cases it was possible to place implants at a planned time. Conclusions: The combination of these recent and innovative regenerative methods seems to be effective in restoring the severe atrophic mandible.</div>
</front>
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<affiliations><list><country><li>Italie</li>
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